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Do human lungs make blood? Here's what a popular study says
Do human lungs make blood? Here's what a popular study says

Time of India

timea day ago

  • Health
  • Time of India

Do human lungs make blood? Here's what a popular study says

It is a basic principle in biology- blood is made in the bone marrow. It's where the cells(hematopoietic stem cells (HSCs))responsible for generating red blood cells, white blood cells, and platelets reside. But a striking study from researchers at UC San Francisco (UCSF) is rewriting that narrative. According to new findings published in Blood, the lungs also contain active blood-forming stem cells, capable of producing not only red blood cells but also platelets and key immune cells. The discovery could have direct implications for stem cell therapies and transplant medicine. The UCSF research team, backed by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH), first made this groundbreaking discovery in 2017when they found that mouse lungs were generating up to half of the animal's platelets, a surprising contribution for an organ never thought to be involved in hematopoiesis. These cells, structurally and functionally similar to bone marrow HSCs, weren't merely circulating through the lungs, but seemed to be living in there. To test how capable these cells actually were, scientists isolated HSCs from both lung and bone marrow tissue, grew them in laboratory conditions, and observed what they produced. 'Both types of HSCs thrived in our gold-standard stem cell experiment, but the lung HSC colonies made more red blood cells and megakaryocytes, while the bone marrow colonies tended to make more immune cells,' explained Mark Looney, MD, professor of medicine and laboratory medicine at UCSF and senior author of the study. Rethinking the bone marrow transplant Bone marrow transplants have long been used to treat cancers like leukemia and other blood-related conditions. They involve harvesting stem cells from a donor, often via a blood draw, and using them to rebuild a patient's blood system. But the UCSF team found that nearly 1 in 5 stem cells isolated in bone marrow transplants actually carried markers specific to lung-derived HSCs, suggesting that current stem cell harvests may be drawing from more than just the bone marrow. 'For decades, bone marrow transplants have been a lynchpin in the treatment of cancers like leukemia,' Looney said. 'The lung HSCs could prove to be a second and significant reservoir of these precious stem cells.' The team also demonstrated that human lung HSCs could restore bone marrow function in mice, a powerful indication that these cells aren't just present, they are fully operational. Why would lungs make blood? That question remains unanswered, but there are theories. 'The lungs are critical to blood circulation, so it's tantalizing to see the lung HSCs as an emergency reservoir for red blood cell and platelet production,' said Looney. One possibility is that these cells activate during times of stress or injury, when the body's demand for oxygen-carrying red cells or clot-forming platelets spikes. The lungs, always at the center of the oxygen exchange process, could provide a rapid-response supply.

'Blood and Water' star Khosi Ngema announces her engagement: officially off the market
'Blood and Water' star Khosi Ngema announces her engagement: officially off the market

IOL News

time2 days ago

  • Entertainment
  • IOL News

'Blood and Water' star Khosi Ngema announces her engagement: officially off the market

Khosi Ngema is officially off the market as she reveals that she is engaged. Image: Instagram Love is in the air for South African actress and singer Khosi Ngema, who recently revealed her engagement in a heartfelt social media post. Beaming with joy, the Blood & Water star shared the exciting news with her fans, marking a new chapter in both her personal and professional journey. The 25-year-old shared on Instagram how life has been exciting and gave a glimpse of the events that took place in her life, including teasing a new project, heartfelt moments with her loved ones and what her engagement looked like. On the last Instagram carousel, she shared a short clip of the engagement set-up, which had red roses on the ground that led up to a heart which had the words 'Will you marry me?' on it. 'Hellooo, I come baack. Lil bit of life lately… Your girl is ENGAGED! Hello?!! This year has been quite reflective and called me to take a lil hermit break to focus on growing and cooking up some stuff. Video Player is loading. Play Video Play Unmute Current Time 0:00 / Duration -:- Loaded : 0% Stream Type LIVE Seek to live, currently behind live LIVE Remaining Time - 0:00 This is a modal window. Beginning of dialog window. Escape will cancel and close the window. Text Color White Black Red Green Blue Yellow Magenta Cyan Transparency Opaque Semi-Transparent Background Color Black White Red Green Blue Yellow Magenta Cyan Transparency Opaque Semi-Transparent Transparent Window Color Black White Red Green Blue Yellow Magenta Cyan Transparency Transparent Semi-Transparent Opaque Font Size 50% 75% 100% 125% 150% 175% 200% 300% 400% Text Edge Style None Raised Depressed Uniform Dropshadow Font Family Proportional Sans-Serif Monospace Sans-Serif Proportional Serif Monospace Serif Casual Script Small Caps Reset restore all settings to the default values Done Close Modal Dialog End of dialog window. Advertisement Next Stay Close ✕ Ad loading 'It's been interesting, weird, exciting, at times testing and full of surprises. Some I can't wait to share! Anyway, how's the year been for you? Sending kisses! Love K,' she wrote The 'Mama' singer also showed off her stunning round-shaped engagement ring as she posed alongside her partner. Ngema has made her mark in the acting industry after she debuted her career as Fikile Bhele on Netflix's hit series 'Blood and Water' in 2020. Her career has taken off since her debut, and she has appeared on multiple other shows, including 'Meet The Khumalos', 'Invasive' and 'Killer Body Count.' Ngema is among many celebrities in our country who have shared exciting updates about their lives, including announcing pregnancies, getting married or getting engaged. Just this month alone, we had beauty queen Mia le Roux sharing that she got engaged to her partner, reality star Kayleigh Schwark revealing that she's expecting her first child, media personality Ayanda Thabethe announcing that she tied the knot and actress Amanda Manku sharing that she's expecting her second child. It is without doubt that happiness has been soaring celebville as many of them continue to embrace new chapters of parenthood or taking the next step in their romantic relationships. Congratulating Ngema on her joyful announcement were her fans, fellow industry colleagues, friends and family. Actor Thabang Molaba commented: 'Wow man. Congratulations fam!!! So happy for you!' Actress Nefisa Mkhabela wrote: 'Oh my goodness! Congratulations beautiful, sooo happy for you!'

‘Fantastic Four' Star Julia Garner Says She's ‘Gonna Still Do My Job' Amid Backlash to Silver Surfer Genderswap
‘Fantastic Four' Star Julia Garner Says She's ‘Gonna Still Do My Job' Amid Backlash to Silver Surfer Genderswap

Yahoo

time15-07-2025

  • Entertainment
  • Yahoo

‘Fantastic Four' Star Julia Garner Says She's ‘Gonna Still Do My Job' Amid Backlash to Silver Surfer Genderswap

Julia Garner doesn't care what people think about her playing Silver Surfer in 'The Fantastic Four: First Steps.' While speaking to BBC at the film's London premiere, Garner was asked about the initial response from some fans who thought a man should play the Silver Surfer. The 'Wolf Man' star said she didn't pay much mind to the discourse and focused on delivering her best version of the character. More from Variety Pedro Pascal Says 'I'm More Aware' of Backlash Over 'Fantastic Four' Casting 'Than Anything I've Ever Done': 'He's Too Old. He's Not Right. He Needs to Shave' 'The Fantastic Four' Director Matt Shakman Reveals the 'Magical' Comics That Inspired the Film in 'Small and Large Ways' (EXCLUSIVE) Anthony Boyle to Play Sam Bankman-Fried Opposite Julia Garner as Caroline Ellison in Netflix's FTX Series 'The Altruists' 'I said, 'I'm just going to still do my job,'' she said of the backlash. She also noted that she plays a variation on the character, adding, 'Also, it's Shalla-Bal, so it's different.' Shalla-Bal, first seen in 'The Silver Surfer' #1 in 1968, is the female counterpart to Norrin Radd, who was featured in 2007's 'Fantastic Four: Rise of the Silver Surfer.' In that film, the humanoid alien was played by Doug Jones and voiced by Laurence Fishburne. As the BBC notes, after the first 'Fantastic Four' trailer debuted, the response to Garner's Surfer was overwhelmingly positive. Garner said she was excited to see the hype from fans. 'I was just happy that people are resonating with it, just like any other project,' Garner added. 'I'm grateful to be at this dance, to be completely honest with you.' Other cast members include Pedro Pascal as Reed Richards, aka Mr. Fantastic; Vanessa Kirby as Sue Storm, aka the Invisible Woman; Joseph Quinn as Johnny Storm, aka the Human Torch; and Ebon Moss-Bachrach as Ben Grimm, aka the Thing. Ralph Ineson plays Galactus, while Paul Walter Hauser, Natasha Lyonne and John Malkovich round out the cast. Best of Variety Final Emmy Predictions: Talk Series and Scripted Variety - New Blood Looks to Tackle Late Night Staples Oscars 2026: George Clooney, Jennifer Lopez, Julia Roberts, Wagner Moura and More Among Early Contenders to Watch New Movies Out Now in Theaters: What to See This Week

Trividia Health, Inc. Announces Preferred Listing of the TRUE METRIX® Blood Glucose Meter and Test Strips for Pennsylvania's Medicaid Recipients
Trividia Health, Inc. Announces Preferred Listing of the TRUE METRIX® Blood Glucose Meter and Test Strips for Pennsylvania's Medicaid Recipients

Business Wire

time07-07-2025

  • Health
  • Business Wire

Trividia Health, Inc. Announces Preferred Listing of the TRUE METRIX® Blood Glucose Meter and Test Strips for Pennsylvania's Medicaid Recipients

FT. LAUDERDALE, Fla.--(BUSINESS WIRE)--Trividia Health, Inc., announced today that its TRUE METRIX® Self-Monitoring Blood Glucose Systems are preferred on all Managed Medicaid Plans and Fee-for-Service Medicaid in Pennsylvania effective July 7 th, 2025. The TRUE METRIX ® portfolio provides a level of performance rooted in science, research and continuous technological advancements. TRUE METRIX Test Strips feature TRIPLE SENSE TECHNOLOGY ®, which ensures clinically accuracy and confidence in results. TRUE METRIX Test Strips are made in the United States, with manufacturing facilities in Fort Lauderdale, Florida. Trividia Health is the largest US manufacturer of pharmacy branded products for people with diabetes. For over 40 years, Trividia Health has been unwavering in its commitment to advance diabetes care. Our team is driven to provide innovative and affordable solutions to help the millions of people living with diabetes manage their blood glucose levels. 'Alongside our pharmacy and distribution partners, Trividia Health's priority is providing accessibility through national coverage with a local presence. Having the TRUE METRIX Self-Monitoring Blood Glucose Meters and Test Strips as preferred products within Pennsylvania allows patients the ability to test with confidence and manage their diabetes,' said Jonathan Chapman, President and CEO of Trividia Health. The TRUE METRIX products are widely available throughout Pennsylvania and are sold under the TRUE METRIX brand name as well as the brand names of the nation's premier retail drug stores, distributors, and independent pharmacies. About Trividia Health Trividia Health, Inc., is a global health and wellness company based in Fort Lauderdale, Florida and a leading developer, manufacturer and marketer of advanced performance and digital management products for people with diabetes. With products sold under TRUE and store brand labels, the company is the partner and supplier of affordable, high-quality blood glucose monitoring and health and wellness solutions for the world's leading retail pharmacies, distributors and mail service providers. For more information, please visit:

Top music professor AXED from Glasgow music school after 16 years over relationship with female student
Top music professor AXED from Glasgow music school after 16 years over relationship with female student

Scottish Sun

time15-06-2025

  • Entertainment
  • Scottish Sun

Top music professor AXED from Glasgow music school after 16 years over relationship with female student

He was the head of jazz for 16 years and was awarded with an OBE in 2019 DISMISSED Top music professor AXED from Glasgow music school after 16 years over relationship with female student Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) A TOP jazz professor has been sacked from a Glasgow music school after 16 years amid allegations over a relationship with a female student. Professor Tommy Smith was given the boot from his post as head of jazz at the Royal Conservatoire of Scotland (RCS) in Glasgow after the claims flagged to bosses. Sign up for Scottish Sun newsletter Sign up 2 Saxophonist Tommy Smith was sacked from his post as Head of Jazz at the RCS Credit: Alamy 2 The Royal Conservatoire of Scotland said it had launched a probe into the claims The prestigious music institution, which boasts King Charles as its patron, launched a probe into the claims and confirmed Smith has since been dismissed. The 58-year-old saxophonist, originally of Wester Hailes in Edinburgh, had been at the helm of jazz studies at the RCS for 16 years. In 2019, Smith was awarded an OBE for services to Jazz from Her Majesty Queen Elizabeth II. He founded the Scottish National Jazz Orchestra and the Tommy Smith Youth Jazz Orchestra, had a global touring career, numerous solo albums and established a record label in his name. A source close to the Conservatoire revealed that the allegations related to his relationship with a female student who was over the age of 18. They told the Scottish Mail on Sunday: "Tommy is a very self-confident man which, coupled with his reputation, gives him a definite magnetism in jazz circles. "But it came as a shock when somebody with such standing ended up being suspended from what is a very prestigious post. "The tip-off to the Royal Conservatoire came from a third party and, given the nature of the allegations, they had little option other than to suspend Tommy. "We all hoped a brilliant musician and tutor could get back to work as soon as possible. "It's hard to overestimate what he has done for jazz in Scotland. He's a generational talent. Dick Halligan performs Spinning Wheel with Blood, Sweat & Tears in 1969 "But the Conservatoire clearly couldn't see a way back for him." A spokesperson for the Royal Conservatoire of Scotland said: "Following a disciplinary investigation and hearing, Tommy Smith has been dismissed. RCS has robust policies in place to ensure the safety and wellbeing of students and staff.' Tommy Smith was contacted for comment.

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