Latest news with #Bronchiectasis
Globe and Mail
15-05-2025
- Health
- Globe and Mail
Bronchiectasis Pipeline Appears Robust With 15+ Key Pharma Companies Actively Working in the Therapeutics Segment
DelveInsight's, 'Bronchiectasis Pipeline Insight 2025' report provides comprehensive insights about 15+ companies and 15+ pipeline drugs in Bronchiectasis pipeline landscape. It covers the pipeline drug profiles, including Bronchiectasis clinical trials and nonclinical stage products. It also covers the Bronchiectasis pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. Discover the latest drugs and treatment options in the Bronchiectasis Pipeline. Dive into DelveInsight's comprehensive report today! @ Bronchiectasis Pipeline Outlook Key Takeaways from Bronchiectasis Pipeline Report In May 2025, Jiangsu HengRui Medicine Co., Ltd. announced a study to Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of RSS0343 Tablets in Patients With Non-cystic Fibrosis Bronchiectasis. In May 2025, Genentech Inc. announced a phase I study to Evaluate the Safety, Tolerability, and Activity of Inhaled GDC-6988 in Patients With Muco-Obstructive Disease. In May 2025, Mannkind Corporation conducted a phase 3 study of the Efficacy and Safety of Clofazimine Inhalation Suspension When Added to Guideline-Based Therapy in Participants With Nontuberculous Mycobacterial Infection. DelveInsight's Bronchiectasis Pipeline report depicts a robust space with 15+ active players working to develop 15+ pipeline therapies for Bronchiectasis treatment. The leading Bronchiectasis Companies such as AstraZeneca, Insmed Incorporated, SolAeroMed, Boehringer Ingelheim, CSL Behring, Thirty Respiratory Limited, RedHill Biopharma Limited, Chiesi Farmaceutici S.p.A., Armata Pharmaceuticals, Alaxia, Parion Sciences, Santhera Pharmaceuticals, Zambon S.p.A. and others. Promising Bronchiectasis Pipeline Therapies such as Clofazimine Inhalation Suspensio, Ambroxol hydrochloride 30 mg, N-acetylcysteine (NAC) 600 mg, AG1321001 (drug), EZ-2053, GDC-6988, RSS0343 Tabella and others. Stay ahead with the most recent pipeline outlook for Bronchiectasis. Get insights into clinical trials, emerging therapies, and leading companies with DelveInsight @ Bronchiectasis Treatment Drugs Bronchiectasis Emerging Drugs Profile Benralizumab: AstraZeneca Benralizumab is a monoclonal antibody used to treat eosinophilic asthma. Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils and basophils. Currently, being evaluated in Phase III stage of clinical trial evaluation to treat Non-cystic Fibrosis Bronchiectasis. S1226: SolAeroMed S1226 formulation consists of aerosolized carbon dioxide (CO2) and nebulized perflubron; which is delivered into the lung. The delivery of this formulation results in an immediate relaxant effect on the patient's constricted airways, supported by a lowering of surface tension in inflamed areas (resulting in enhanced bronchial dilation) and possible clearing of mucus plugs of blocked rescue treatment works on both physiological and biophysical principles offering a unique approach to relieving airway obstruction. CO2 is a potent, but short acting bronchial smooth muscle relaxant. Perflubron is a non-toxic (biocompatible) medical perfluorocarbon with mucolytic and surfactant properties that acts synergistically with CO2 to provide a much greater and more prolonged broncho-dilatory effect. The drug product is hypothesized to open constricted airways through at least three distinct mechanisms. Firstly, through the relaxant effect of CO2 (alone and dissolved into perflubron) on constricted airway smooth muscle; secondly, by lowering surface tension in the inflamed airways; and finally by possibly facilitating penetration and lubrication of mucus plugs, thus enhancing mucociliary clearance. Furthermore it works by an entirely different mechanism to the ß-adrenergic agonists and thus complements, rather than replaces, existing treatments. Brensocatib: Insmed Brensocatib is a small molecule, oral, reversible inhibitor of dipeptidyl peptidase I (DPP1) being developed by Insmed for the treatment of patients with bronchiectasis. DPP1 is an enzyme responsible for activating neutrophil serine proteases (NSPs), such as neutrophil elastase, in neutrophils when they are formed in the bone marrow. Neutrophils are the most common type of white blood cell and play an essential role in pathogen destruction and inflammatory mediation. In chronic inflammatory lung diseases, neutrophils accumulate in the airways and result in excessive active NSPs that cause lung destruction and inflammation. Brensocatib may decrease the damaging effects of inflammatory diseases such as bronchiectasis by inhibiting DPP1 and its activation of NSPs. The Bronchiectasis Pipeline Report Provides Insights into The report provides detailed insights about companies that are developing therapies for the treatment of Bronchiectasis with aggregate therapies developed by each company for the same. It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Bronchiectasis Treatment. Bronchiectasis Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects. Bronchiectasis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Bronchiectasis market Explore groundbreaking therapies and clinical trials in the Bronchiectasis Pipeline. Access DelveInsight's detailed report now! @ New Bronchiectasis Drugs Pulmonary Fibrosis Companies AstraZeneca, Insmed Incorporated, SolAeroMed, Boehringer Ingelheim, CSL Behring, Thirty Respiratory Limited, RedHill Biopharma Limited, Chiesi Farmaceutici S.p.A., Armata Pharmaceuticals, Alaxia, Parion Sciences, Santhera Pharmaceuticals, Zambon S.p.A. and others. Bronchiectasis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as Inhalation Inhalation/Intravenous/Oral Intranasal Intravenous Intravenous/ Subcutaneous NA Oral Oral/intranasal/subcutaneous Parenteral Subcutaneous Bronchiectasis Products have been categorized under various Molecule types such as Antibody Antisense oligonucleotides Immunotherapy Monoclonal antibody Peptides Protein Recombinant protein Small molecule Stem Cell Vaccine Unveil the future of Bronchiectasis Treatment. Learn about new drugs, pipeline developments, and key companies with DelveInsight's expert analysis @ Bronchiectasis Market Drivers and Barriers Scope of the Bronchiectasis Pipeline Report Coverage- Global Bronchiectasis Companies- AstraZeneca, Insmed Incorporated, SolAeroMed, Boehringer Ingelheim, CSL Behring, Thirty Respiratory Limited, RedHill Biopharma Limited, Chiesi Farmaceutici S.p.A., Armata Pharmaceuticals, Alaxia, Parion Sciences, Santhera Pharmaceuticals, Zambon S.p.A. and others. Bronchiectasis Pipeline Therapies- Clofazimine Inhalation Suspensio, Ambroxol hydrochloride 30 mg, N-acetylcysteine (NAC) 600 mg, AG1321001 (drug), EZ-2053, GDC-6988, RSS0343 Tabella and others. Bronchiectasis Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination Bronchiectasis Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III Get the latest on Bronchiectasis Therapies and clinical trials. Download DelveInsight's in-depth pipeline report today! @ Bronchiectasis Companies, Key Products and Unmet Needs Table of Content Introduction Executive Summary Bronchiectasis: Overview Pipeline Therapeutics Therapeutic Assessment Bronchiectasis – DelveInsight's Analytical Perspective Late Stage Products (Phase III) Benralizumab: AstraZeneca Drug profiles in the detailed report….. Mid Stage Products (Phase II) S1226: SolAeroMed Drug profiles in the detailed report….. Early Stage Products (Phase I) CSL787: CSL Behring Drug profiles in the detailed report….. Preclinical and Discovery Stage Products AP-PA02: Armata Pharmaceuticals Drug profiles in the detailed report….. Inactive Products Bronchiectasis Key Companies Bronchiectasis Key Products Bronchiectasis- Unmet Needs Bronchiectasis- Market Drivers and Barriers Bronchiectasis- Future Perspectives and Conclusion Bronchiectasis Analyst Views Bronchiectasis Key Companies Appendix About Us DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve. Media Contact Company Name: DelveInsight Business Research LLP Contact Person: Yash Bhardwaj Email: Send Email Phone: 09650213330 Address: 304 S. Jones Blvd #2432 City: Las Vegas State: NV Country: United States Website:
Daily Mail
22-04-2025
- Entertainment
- Daily Mail
Superfit Iris Law proves she can put herself in pole position as she shows off her skills and washboard abs in new pole dancing clip
Iris Law has shared one of her hidden talents in a new social media clip as she revealed that she can pole dance. The model, 24, showcased her skills in the new video which she posted to Instagram this week among a highlight reel of what she has been up to recently. Iris, who's the daughter of Hollywood's Jude Law and actress Sadie Frost, could be seen showing off her flexibility with a move called the 'side-saddle superman'. The impressive move involves bringing your legs up behind you so that you are flying in a horizontal position. Iris has previously said of her training programme: 'I really like running on a running machine, spinning and hot yoga', before adding pole dancing to her regime. The star also shared some racy snaps from a recent getaway to her Instagram Story, posing topless as she ate nectarines by the sea. Iris also set pulses racing as she posed topless alongside a stunning pal while soaking up the sun in her latest eye popping photo dump to mark Earth Day. She took to Instagram on Monday with a slew of snaps from her many getaways and modelled skimpy swimmer before removing her bikini top to flash ample side boob. Iris and her friend sat on rocks overlooking the clear blue ocean while snacking on fruit before heading back into the cooling water. The model continued to showcase her jaw-dropping figure and taut abs as she later slipped into another tiny two piece and beamed for the camera. Wherever she was in the world Iris made sure to make the most of her lavish location, as she enjoyed a boat trip and dined on traditional dishes as well as a spot of Yoga. She captioned the post: 'Earthday tomorrow so thank you. it's too much'. Iris' mum Sadie, 59, is also a yoga enthusiast and has ditched her 90s party girl label for leggings and fitness, rebranding herself as a yoga-teaching film director. The actress and former socialite, who is a mother of four and grandmother to one, not only had A-lister party pals but she was also married to British heartthrob, Jude Law and Spandau Ballet guitarist Gary Kemp. Reflecting on her partying days in a new interview, Sadie has revealed the hedonistic lifestyle also had an impact on her health as she went onto suffer from both anxiety and asthma. She has now credited yoga with helping her manage her anxiety and panic attacks, which she attributes in part to her childhood lung disease, Bronchiectasis. She told OK Magazin e of her changing friendships: 'Before, I would operate in a group, a clan, a crew. I still have some very healthy friendships, but I actually enjoy my own time, too.' 'I've always struggled with certain breathing situations because I had asthma and that caused anxiety', she added. 'So for me, yoga, meditation, diet and breathing have always been really important because if I'm out of balance or out of sync, not connected to myself and to my breath, I'm going to be a very unbalanced, unhappy person.' She then went on to reveal that she has gained a group of 'yogi friends' and still has a very close bond with her long-term best friends like Zoe Grace, Frances Ruffelle and Rosemary Ferguson. Sadie made her big-screen debut in Empire State in 1987, but it was her role as Lucy Westenra in Francis Ford Coppola's Bram Stoker's Dracula four years later that made her a household name. Throughout the 1990s, she also appeared in several music videos, including Pulp's Common People. Iris dined on traditional dishes as well as taking in a spot of Yoga Living in north London at the time, she became a key figure in the party-loving Primrose Hill set, alongside Donna Air, the Gallagher brothers, Jude Law, Patsy Kensit, and Jonny Lee Miller. In recent years, her focus has shifted from the social scene to her deep commitment to yoga, regularly traveling to India to further her knowledge of the Jivamukti method. Sadie is currently celebrating major success as the director of the critically acclaimed documentary film Twiggy, which explores the life and career of British icon Dame Twiggy Lawson. She has worked hard for this achievement but she has credited her approach to health and wellness for allowing her to truly enjoy it. Alongside her professional accomplishments, she is also embracing her role as a grandmother to her first grandchild, Daya Wildrose Mallory Kemp, the daughter of her eldest son Finlay and his wife Charlotte Mallory. The mother-of-four also shares three children with ex Jude their son Rafferty, 28, daughter Iris, 24 and youngest Rudy, 22. She also was in an on-off relationship with businessman Darren Strowger for eight years, before Sadie confirmed she was single in an interview last year.
Daily Mail
21-04-2025
- Entertainment
- Daily Mail
Iris Law poses TOPLESS alongside a stunning pal while soaking up the sun in latest eye-popping photo dump
Iris Law set pulses racing as she posed topless alongside a stunning pal while soaking up the sun in her latest eye popping photo dump to mark Earth Day. The 24-year-old daughter of Jude Law and Sadie Frost took to Instagram on Monday with a slew of snaps from her many getaways and modelled skimpy swimmer before removing her bikini top to flash ample side boob. Iris and her friend sat on rocks overlooking the clear blue ocean while snacking on fruit before heading back into the cooling water. The model continued to showcase her jaw-dropping figure and taut abs as she later slipped into another tiny two piece and beamed for the camera. Wherever she was in the world Iris made sure to make the most of her lavish location, as she enjoyed a boat trip and dined on traditional dishes as well as a spot of Yoga. She captioned the post: 'Earthday tomorrow so thank you. it's too much'. Iris' mum Sadie, 59, is also a yoga enthusiast and has ditched her 90s party girl label for leggings and fitness, rebranding herself as a yoga-teaching film director. The actress and former socialite, who is a mother of four and grandmother to one, not only had A-lister party pals but she was also married to British heartthrob, Jude Law and Spandau Ballet guitarist Gary Kemp. Reflecting on her partying days in a new interview, Sadie has revealed the hedonistic lifestyle also had an impact on her health as she went onto suffer from both anxiety and asthma. She has now credited yoga with helping her manage her anxiety and panic attacks, which she attributes in part to her childhood lung disease, Bronchiectasis. She told OK Magazin e of her changing friendships: 'Before, I would operate in a group, a clan, a crew. I still have some very healthy friendships, but I actually enjoy my own time, too.' 'I've always struggled with certain breathing situations because I had asthma and that caused anxiety', she added. 'So for me, yoga, meditation, diet and breathing have always been really important because if I'm out of balance or out of sync, not connected to myself and to my breath, I'm going to be a very unbalanced, unhappy person.' She then went on to reveal that she has gained a group of 'yogi friends' and still has a very close bond with her long-term best friends like Zoe Grace, Frances Ruffelle and Rosemary Ferguson. She captioned the post: 'Earthday tomorrow so thank you. it's too much'. Sadie made her big-screen debut in Empire State in 1987, but it was her role as Lucy Westenra in Francis Ford Coppola's Bram Stoker's Dracula four years later that made her a household name. Throughout the 1990s, she also appeared in several music videos, including Pulp's Common People. Living in north London at the time, she became a key figure in the party-loving Primrose Hill set, alongside Donna Air, the Gallagher brothers, Jude Law, Patsy Kensit, and Jonny Lee Miller. In recent years, her focus has shifted from the social scene to her deep commitment to yoga, regularly traveling to India to further her knowledge of the Jivamukti method. Sadie is currently celebrating major success as the director of the critically acclaimed documentary film Twiggy, which explores the life and career of British icon Dame Twiggy Lawson. She has worked hard for this achievement but she has credited her approach to health and wellness for allowing her to truly enjoy it. Alongside her professional accomplishments, she is also embracing her role as a grandmother to her first grandchild, Daya Wildrose Mallory Kemp, the daughter of her eldest son Finlay and his wife Charlotte Mallory. The mother-of-four also shares three children with ex Jude their son Rafferty, 28, daughter Iris, 24 and youngest Rudy, 22.
