Latest news with #CGT
Scoop
5 hours ago
- Business
- Scoop
Gordon Campbell: On Wealth Taxes And Capital Flight
In the wake of the Greens' alternative Budget – and the criticism levelled at it – it seems pretty obvious that when it comes to tax policy, Labour's only election campaign concession to left wing voters is going to be a capital gains tax (CGT). A wealth tax is not on the cards. Yet in the run-up to next year's election, even a CGT is going to be demonised as a plunge into radicalism. It is a sign of just how restrictive the politics of progressive taxation are in New Zealand.
Yahoo
16 hours ago
- Business
- Yahoo
Medable Introduces Long-Term Follow-Up Model for Cell & Gene Therapy (CGT) Trials to Reduce Costs and Improve Patient Access
New digital-first solution enables patient engagement and retention while maintaining scientific rigor throughout 15-year CGT trials PALO ALTO, Calif., May 28, 2025--(BUSINESS WIRE)--Medable Inc., a leading technology platform provider for decentralized clinical trials, today unveiled its digital-first Long-Term Follow-Up (LTFU) model for cell and gene therapy (CGT) trials. Medable's platform reduces the burden on patients and sites involved in complex CGT trials and enhances scientific integrity with sustainable data capture across the FDA-required 15-year follow-up period for certain CGTs, including those using genome-editing techniques like CRISPR-Cas9. This extended monitoring period is essential for tracking delayed adverse events, understanding the durability of the therapy, and ensuring the long-term impact on patients – but can add significant hardships. CGTs offer transformative potential yet they also require prolonged safety monitoring, often spanning 15 years post-treatment. Traditional models for LTFU impose logistical and financial challenges on participants, contributing to lower participation and high attrition rates over time. According to a 2024 survey conducted by the Emily Whitehead Foundation and Catalyst Healthcare Consulting, 20% of CAR T-cell therapy patients stop participating in long-term follow-up altogether, with 80% of that group ceasing participation at or after five years post-treatment. Distance to sites, lack of awareness about local follow-up options, and burdensome travel are frequently cited as key barriers. "Long-term follow-up is essential to ensure the durability and safety of advanced therapies, but the current system isn't working for patients or sponsors," said Dr. Pamela Tenaerts, Chief Medical Officer at Medable. "With our new LTFU model, we're reimagining how post-treatment data is captured - putting patients at the center while ensuring scientific and regulatory rigor." Medable's digital-first LTFU offering includes: Remote and Hybrid Patient Interaction: Patients can engage in follow-up through flexible virtual, in-person, or blended formats that meet their individual needs and life circumstances. Seamless Transition from Parent Trials: Integrated workflows and data continuity ensure a frictionless handoff from interventional studies to long-term observational follow-up. Patient-First Data Capture and Adherence Monitoring: Leveraging mobile technology, patient reported questionnaires and local healthcare providers to track key endpoints and ensure consistent participation over time. Personalized Patient Communication: Ongoing engagement through tailored content, reminders, and support tools to build trust and maintain long-term connection. By embracing a digital, patient-centric approach, Medable's model addresses key gaps in traditional LTFU execution – improving retention, increasing diversity, and reducing the long-term cost burden for both sponsors and sites. Learn more about Medable's new digital-based LTFU model at American Society of Clinical Oncology's (ASCO) 2025 Annual Meeting (May 30-June 3) in Chicago at Medable Booth #10105. About Medable Medable is on a mission to get effective therapies to people faster. Its digital clinical trials platform enhances speed, scale, and patient access in clinical research, accelerating medicines for thousands of conditions without treatment or cure. Awarded Best Digital Health Solution by the Galien Foundation, Medable's platform has been deployed in nearly 400 trials in 70 countries and 120 languages, serving more than one million patients globally. Medable is a privately held, venture-backed company headquartered in Palo Alto, California, and was listed for the second year in a row on the Inc. 5000 in 2024. View source version on Contacts Media Contact: Lisa Barbadora, Barbadora INK for Medable+1 (610) 420-3413lbarbadora@ / media@
Gulf Today
19 hours ago
- Politics
- Gulf Today
French teacher suspended for 2 months after holding minute's silence in class for Gaza victims
A teacher in France has been suspended for nearly two months after holding a minute's silence for Gaza victims in her class. The physics and chemistry teacher at the Janot-Curie high school in Sens, Yens, was told by the local education authority that she failed to respect the principle of neutrality when she was suspended on 31 March. On 25 March, days after resumed Israeli strikes ended the ceasefire in the Gaza Strip, the teacher is accused by the Dijon education authority of having organised a minute of silence for the Palestinians killed in the week before. This was done on her own 'personal initiative', the education authority told The Independent – but this claim has been disputed by teaching unions. "Respecting neutrality is a duty for civil servants, enshrined in their status, and any failure to comply with this obligation triggers disciplinary proceedings," the authority explained. But the education branches of French unions FO, CGT and Sud insist that the students had requested the silence. 'The teacher agreed, at the end of her class, to observe this time of homage with the students who wished to do so," they said. A child cries as Palestinians gather to receive a hot meal at a food distribution point in the Nuseirat camp for refugees in the central Gaza Strip on May 24, 2025. Agence France-Presse "We demand that this teacher be reinstated immediately, that all charges be dropped, and that her dignity be officially restored in the eyes of the school, staff, and parents," the unions added in a joint statement. Equally outraged were political figures including the first-secretary of the Socialist Party (PS), Olivier Faure. 'A minute of silence requested by the students, with those who do not want to join being able to withdraw, to pay tribute to the victims in Gaza, and it is the teacher who is suspended... really???' he wrote on X. 'We are standing on our heads.' It comes as France's relationship with Israel becomes increasingly strained, after Israeli ministers responded furiously to condemnation by Western allies over its actions in the Gaza Strip, including the previous 11-week blockade on aid and its resumed offensive. Strongest condemnation President Emmanuel Macron joined the UK and Canada in issuing their strongest condemnation yet of Netanyahu's government. A statement demanded Israeli Prime Minister Benjamin Netanyahu halt his 'egregious' actions in Gaza, threatening 'concrete actions' over the 'intolerable' human suffering inflicted on the enclave. Following the fatal shooting of two Israeli embassy staffers in Washington DC on Wednesday night, Netanyahu echoed earlier statements by fellow ministers laying the blame at the door of the UK, France and Canada. 'I say to President Macron, Prime Minister Carney and Prime Minister Starmer: When mass murderers, rapists, baby killers and kidnappers thank you, you're on the wrong side of justice,' he wrote on social media. 'You're on the wrong side of humanity and you're on the wrong side of history.' The Independent
The Herald Scotland
5 days ago
- Business
- The Herald Scotland
What is the best way to save for your grandchildren?
A junior ISA is one of the most popular ways of saving money for grandchildren. These accounts offer tax-free growth, meaning any interest or gains are not subject to capital gains tax (CGT). Contributions can be made up to a specific annual limit of £9,000 and the money is accessible by your grandchild when they turn 18. The benefit of a junior ISA is that the money doesn't form part of your estate, which means it won't be subject to inheritance tax (IHT). This assumes that any gifts made to the junior ISA fall under the IHT gifting allowances or otherwise you survive for seven years from the date of the gift. A junior SIPP (self-invested personal pension) is another a great way to invest for your grandchild's long-term financial future. Unlike junior ISAs, a junior SIPP is designed specifically for retirement savings. The key benefit of a junior SIPP is the tax relief on contributions. You can contribute up to £2,880 per tax year and the government adds 20% basic rate tax relief, boosting the total contribution to £3,600. However, the funds are locked in until your grandchild reaches at least 57 years old. While this may seem a long way off, the advantage of starting early is the significant compound growth over the years, which could potentially result in a substantial retirement fund. A junior SIPP can be a fantastic way to ensure your grandchild has a comfortable retirement, even if they don't have the means to contribute themselves. Once your grandchild turns 18, a lifetime ISA (LISA) can be a valuable tool to help them save for their first home or retirement. The government offers a 25% bonus annually on contributions, which can be a significant boost. Each year, until they turn 50, your grandchild can contribute up to £4,000 and they'll receive a bonus of up to £1,000, making it an attractive option for young adults just starting to save. All interest accumulated within a LISA is tax-free too. A LISA can act as a stepping stone toward helping your grandchild get on the property ladder or saving for their future retirement. While the funds can't be accessed until age 60 (unless used for a first home purchase), it's an investment that can grow significantly over time. When thinking 'what is the best way to leave money to my grandchildren' it's important to consider the potential IHT implications. The amount you 'gift' to your grandchildren could be subject to IHT, depending on how much you leave and when you leave it. However, there are several ways to reduce this potential liability, such as gifting money directly to grandchildren through ISAs or trusts. By making gifts to grandchildren within your annual capital gift allowance – up to £3,000 a year - or setting up a trust, you can reduce the value of your estate, ensuring that more of your wealth passes to the next generation without being impacted by IHT. It's also possible to use other exemptions such as regular gifts from surplus income. Any gifts made that fall outside of these allowances are subject to the 'seven-year rule,' meaning they will only fall outside of your estate once you have survived for seven years from the date of the gift. The best way to leave money to your children or grandchildren depends on your family's wealth, your goals and your wishes for how the money should be used. There is no one-size-fits-all approach, but with careful planning, you can create a strategy that helps you achieve both your own financial goals and those of your grandchildren. Paul Hancock is a senior wealth planner at Canaccord Wealth
The Independent
5 days ago
- Politics
- The Independent
Teacher suspended after holding minute's silence for Gaza victims
A teacher in France has been suspended for nearly two months after holding a minute's silence for Gaza victims in her class. The physics and chemistry teacher at the Janot-Curie high school in Sens, Yens, was told by the local education authority that she failed to respect the principle of neutrality when she was suspended on 31 March. On 25 March, days after resumed Israeli strikes ended the ceasefire in the Gaza Strip, the teacher is accused by the Dijon education authority of having organised a minute of silence for the Palestinians killed in the week before. This was done on her own 'personal initiative', the education authority told The Independent - but this claim has been disputed by teaching unions. "Respecting neutrality is a duty for civil servants, enshrined in their status, and any failure to comply with this obligation triggers disciplinary proceedings," the authority explained. But the education branches of French unions FO, CGT and Sud insist that the students had requested the silence. 'The teacher agreed, at the end of her class, to observe this time of homage with the students who wished to do so," they said. "We demand that this teacher be reinstated immediately, that all charges be dropped, and that her dignity be officially restored in the eyes of the school, staff, and parents," the unions added in a joint statement. Equally outraged were political figures including the first-secretary of the Socialist Party (PS), Olivier Faure. 'A minute of silence requested by the students, with those who do not want to join being able to withdraw, to pay tribute to the victims in Gaza, and it is the teacher who is suspended... really???' he wrote on X. 'We are standing on our heads.' It comes as France's relationship with Israel becomes increasingly strained, after Israeli ministers responded furiously to condemnation by Western allies over its actions in the Gaza strip, including the previous 11-week blockade on aid and its resumed offensive. President Emmanuel Macron joined the UK and Canada in issuing their strongest condemnation yet of Netanyahu's government. A statement demanded Israeli prime minister Benjamin Netanyahu halt his 'egregious' actions in Gaza, threatening 'concrete actions' over the 'intolerable' human suffering inflicted on the enclave. Following the fatal shooting of two Israeli embassy staffers in Washington DC on Wednesday night, Mr Netanyahu echoed earlier statements by fellow ministers l aying the blame at the door of the UK, France and Canada. 'I say to President Macron, Prime Minister Carney and Prime Minister Starmer: When mass murderers, rapists, baby killers and kidnappers thank you, you're on the wrong side of justice,' he wrote on social media. 'You're on the wrong side of humanity and you're on the wrong side of history.'
