Latest news with #CZ
Forbes
6 days ago
- Health
- Forbes
Chan Zuckerberg Initiative Introduces New GREmLN Model For Genetics
3D illustration of a DNA molecule with sparkling effects symbolizing complexity and genetic ... More diversity. Futuristic concept of genomics, precision medicine, and computational life sciences. If you've been paying attention to modern research and AI, you know that genetics is a major application of this technology to our lives. Alphafold, for which its founders received a Nobel prize in science, is a major example, but it's just the tip of the iceberg when it comes to what AI is doing in healthcare, and in genetics in particular. This month we have a new announcement from the Chan Zuckerberg Initiative backed by Mark Zuckerberg and Melissa Chan that contemplates a brand new system called GREmLN (Gene Regulatory Embedding-based Large Neural model) for identifying cellular behavior. It may help with cancer research and work on other diseases. Part of the project involves an imaging technique, and assistance in developing software for scientists. There's also what CZ calls a 'single cell data set' of 1 billion cells, developed with 10X Genomics and Ultima Genomics. From reading documentation, it sounds like what this means is that teams assembled data on no less than a billion cells, in order to build a collective model of what an average cell would look like and how it would function. The new model, scientists suggest, can help to characterize genetic drivers of disease, and find new ways to restore diseased cells to health. Four Major Goals and Challenges Amongst the announcement of this ground-breaking resource, spokespersons at CZ identify four broader objectives scientists are reaching for: One involves building an AI-based virtual cell model – which GREmLN is presumably instrumental in. Another is 'developing novel imaging technology to map, measure and model complex systems,' which sounds like a similar type of exercise. Reportedly, the teams also hope to figure out how to directly sense inflammation in the body, and to harness the human immune system for various kinds of immunotherapy. Parsing these objectives further, you can see how the new GREmLN model will drive research on what the CZ Institute calls 'molecular logic' or the study of how parts of a cell interact or work together. What are Biohubs? A press release from Chan Zuckerberg also mentions the creation of Biohubs as laboratories fueling collaborative development, or, in the words of spokespersons, 'cross-disciplinary research institutions.' ChatGPT provides a definition of a Biohub, and points out that the Chan Zuckerberg Biohubs are not the same as a series of Biohubs developed by the World Health Organization. 'Biohubs are collaborative research centers designed to accelerate breakthroughs in biomedical science by fostering interdisciplinary cooperation, sharing resources, and facilitating innovation,' the model notes. 'Typically established through partnerships between universities, research institutions, healthcare providers, government agencies, and industry leaders, Biohubs aim to address complex biological and medical challenges by combining expertise across biology, medicine, engineering, computing, and data science. … Prominent examples include the Chan Zuckerberg Biohub, which unites Stanford, UCSF, and UC Berkeley researchers to tackle infectious diseases and advance biomedical knowledge through open science.' Of the WHO Biohubs: 'A totally separate WHO initiative aimed at sharing biological materials (like virus samples with pandemic potential) among member states… So, while (CZ Biohubs and WHO Biohubs) share the 'Biohub' name, their missions, governance, and affiliations are entirely distinct.' The concept, however, is the same – scientists are banding together to do more innovative work on cell structure, for example, in nucleus and mitochondria DNA. A little research shows some of the distinctions between different types of DNA present in a cell. A lot of the DNA is isolated in the nucleus of the cell, but there's also mitochondria, less attached to that central cluster. Literature Weighs In Fans of Madeleine L'Engle's youth fiction in the 1980s will note that her work explored the idea of subcellular entities and their impact on macroscopic systems. Just for fun. I ask ChatGPT about L'Engle's impact on modern cellular and genomic research. 'Madeleine L'Engle's work didn't explicitly prefigure specific contemporary research into genetics or mitochondria, but her writing, particularly A Wrinkle in Time (1962), A Wind in the Door (1973), and the rest of her Time Quintet, did anticipate broad scientific and philosophical themes related to cellular biology, mitochondrial function, interconnectedness, and universal harmony,' the model said. 'In A Wind in the Door, for instance, L'Engle explores the concept of 'farandolae,' fictional microscopic entities within mitochondria, whose harmony or disharmony directly affects the health of living organisms and even the universe. Her vision captured a holistic view of biology, recognizing mitochondria as fundamental life engines, long before mainstream science widely emphasized mitochondria's central role in health, aging, and diseases.' How many readers remember the farandolae, which L'Engle characterized in promoting a kind of social symbiosis that was a more prominent idea in a less data-driven age? 'The young farandolae cannot fill an adult role, so they maintain a parasitic existence on the adult farae,' writes a poster on Literature Stack Exchange, where human readers get together to ruminate on different aspects of a text. 'In fact, so long as they are under the influence of the Echthroi, they revel in their parasitism. It is all taking and no giving…' In any case, ChatGPT provides this summary: 'Though not predictive in a literal scientific sense, L'Engle's imaginative storytelling prefigured ideas in modern genetics and mitochondrial research—particularly notions of cellular symbiosis, bioenergetics, systemic interconnectedness, and the vital relationship between microscopic structures and macrocosmic health.' Driving Further Change It's easy to see how these partnerships will allow scientists to work more proactively on disease solutions. I thought this news was worth covering as we move through a banner year for artificial intelligence in healthcare. We are finding use cases everywhere, from diagnosis, to scheduling, to the kinds of research that support these clinical solutions. That's a feather in AI's cap. However, we just might still have a place for the philosophical, sometimes fictional portrayal of such systems, as in L'Engle's work that leans more into the speculative than the technical approach. What do you think?
Cision Canada
23-07-2025
- Business
- Cision Canada
Think Like Vitalik, Trade Like Buffett: Edgen Reconceptualizes How Retail Investors Navigate Digital Assets
Edgen's Megabrain Injects Iconic Minds Into Everyday Crypto Decisions HONG KONG, July 23, 2025 /CNW/ -- Edgen, an AI-driven market intelligence platform, is redefining how retail investors navigate digital assets. Edgen's foundational architecture, powered by its proprietary Efficient Decision Guidance Model (EDGM), is purpose-built to process vast market inputs from on-chain transactions to social media pulses and return coherent, contextual guidance within seconds. Where traditional analytics platforms rely on charts and data grids, Edgen frames insight in motion, real-time, conversational, and synthesized. Today, Edgen launches its latest feature, Megabrain Investors' Picks, a first-of-its-kind feature that simulates how globally recognized investors and public figures might evaluate specific crypto assets. With one query, users can receive AI-generated opinions "as if" they were speaking to Warren Buffett, Vitalik Buterin, Nancy Pelosi, Binance's CZ, and other widely followed financial minds. Megabrain Investors' Picks addresses the growing need for retail investors, who are often operating with limited context and are experiencing information overload, struggling to make confident decisions in a highly volatile market. It is not a chatbot nor a parody, and not quite financial advice either, although for many retail investors overwhelmed by opinion noise, it might function like something close. At its core, Megabrain compresses massive amounts of public information like speeches, historical decisions, known holdings, quotes, etc., into stylized, fast-response simulations. The voices are fictionalized, but the tone and positioning reflect a very real investing logic. "Retail investors are over-informed but under-aligned," said Sean Tao, CEO & Co-Founder of Edgen. "There's no shortage of analysis online, but what's often missing is personality-guided inference, such as how someone like Warren Buffett would react, not just what the market did. These nuances are valuable, especially for those making decisions alone." The feature doesn't bury users in data, nor does it attempt to predict prices. Instead, it offers contextual tone, the kind that institutional players absorb over years of watching a portfolio manager speak, or observing how certain personalities lean when markets shift. Unlike static market reports or long-form analysis, Megabrain Investors' Picks invites rapid comparison. By asking the same question across multiple personalities, users can watch the philosophical spread unfold. For example, Buffett's caution against Trump's enthusiasm, or Buterin's nuance against CZ's pragmatism. It becomes a live case study in sentiment divergence, delivered in natural language and without pretense. Edgen has already been gradually positioning itself as a crypto-native insights layer with mass accessibility features like Edgen Search (real-time token data plus conversational summaries), Portfolio AI, and narrative tools that interpret sentiment shifts. Megabrain adds the missing layer: Voice Opinions. It may be simulated, but it is specific, sharp, and occasionally surprising. About Edgen Edgen is the leading AI-powered market intelligence operating system in the crypto space. Through its proprietary Efficient Decision Guidance Model (EDGM), the platform transforms high-barrier institutional-grade strategies into universally accessible smart tools. Pioneering the "Cognition-as-a-Service" (CaaS) architecture, Edgen integrates modular AI agents, real-time social sentiment analysis, and on-chain analytics to empower retail traders and independent analysts to navigate crypto markets with institutional-grade precision. Backed by crypto-native funds such as Framework Ventures and North Island Ventures, Edgen's technical team combines former Wall Street quantitative trading experts and core Web3 protocol developers, collectively building the cognitive infrastructure for next-generation open finance.
Yahoo
16-07-2025
- Business
- Yahoo
Rigetti Demonstrates Industry's Largest Multi-Chip Quantum Computer; Halves Two-Qubit Gate Error Rate
BERKELEY, Calif., July 16, 2025 (GLOBE NEWSWIRE) -- Rigetti Computing, Inc. (Nasdaq: RGTI) ('Rigetti' or the 'Company'), a pioneer in full-stack quantum-classical computing, today announced that it has achieved its mid-year performance milestone of 99.5% median two-qubit gate* fidelity on its modular 36-qubit system, a 2x reduction in median two-qubit gate error rate from Rigetti's previous best results on its 84-qubit single chip Ankaa™-3 system. Composed of four 9-qubit chips ('chiplets') tiled together, the 36-qubit system is based on Rigetti's proprietary modular chip technology and unlocks the Company's path to building a 100+ qubit chiplet-based system. Rigetti plans to launch its 36-qubit system on August 15, and remains on track to release its 100+ qubit chiplet-based system at 99.5% median two-qubit gate fidelity before the end of 2025. 'We benefit from the many advantages of superconducting qubits, including gate speeds more than 1,000x faster than other modalities like ion trap and pure atoms, and scalability. By leveraging well-known techniques from the semiconductor industry, we've developed proprietary technology that we believe is critical to enable scaling to higher qubit count systems,' says Dr. Subodh Kulkarni, Rigetti CEO. 'We look forward to sharing more updates when we release our operating results for the second quarter of 2025.' *Rigetti implemented CZ gates, which are a commonly used two-qubit gate for executing quantum circuits and have equivalent computational power to iSWAP gates. About RigettiRigetti is a pioneer in full-stack quantum computing. The Company has operated quantum computers over the cloud since 2017 and serves global enterprise, government, and research clients through its Rigetti Quantum Cloud Services platform. In 2021, Rigetti began selling on-premises quantum computing systems with qubit counts between 24 and 84 qubits, supporting national laboratories and quantum computing centers. Rigetti's 9-qubit Novera™ QPU was introduced in 2023 supporting a broader R&D community with a high-performance, on-premises QPU designed to plug into a customer's existing cryogenic and control systems. The Company's proprietary quantum-classical infrastructure provides high-performance integration with public and private clouds for practical quantum computing. Rigetti has developed the industry's first multi-chip quantum processor for scalable quantum computing systems. The Company designs and manufactures its chips in-house at Fab-1, the industry's first dedicated and integrated quantum device manufacturing facility. Learn more at Rigetti Computing Media Contact:press@ Cautionary Language Concerning Forward-Looking StatementsCertain statements in this communication may be considered 'forward-looking statements' within the meaning of the federal securities laws, including statements with respect to the Company's expectations with respect to its future success and performance, including expectations that the performance milestone unlocks the Company's path to building a 100+ qubit chiplet-based system, expectations to launch its 36-qubit system on August 15, expectations to release its 100+ qubit chiplet-based system at 99.5% median two-qubit gate fidelity before the end of 2025, expectations to benefit from the advantages of superconducting qubits, the belief that the developed proprietary technology is critical to enable scaling to higher qubit count systems, the belief that Rigetti's demonstration is the largest multi-chip quantum computer, and the potential of the Company's business and quantum computing generally. These forward-looking statements are based upon estimates and assumptions that, while considered reasonable by the Company and its management, are inherently uncertain. Factors that may cause actual results to differ materially from current expectations include, but are not limited to: the Company's ability to achieve milestones, technological advancements, including with respect to its technology roadmap; the ability of the Company to obtain government contracts successfully and in a timely manner and the availability of government funding; the potential of quantum computing; the success of the Company's partnerships and collaborations, including the strategic collaboration with Quanta; the Company's ability to accelerate its development of multiple generations of quantum processors; the outcome of any legal proceedings that may be instituted against the Company or others; the ability to maintain relationships with customers and suppliers and attract and retain management and key employees; costs related to operating as a public company; changes in applicable laws or regulations; the possibility that the Company may be adversely affected by other economic, business, or competitive factors; the Company's estimates of expenses and profitability; the evolution of the markets in which the Company competes; the ability of the Company to implement its strategic initiatives and expansion plans; the expected use of proceeds from the Company's past and future financings or other capital; the sufficiency of the Company's cash resources; unfavorable conditions in the Company's industry, the global economy or global supply chain, including rising inflation and interest rates, deteriorating international trade relations, political turmoil, natural catastrophes, warfare and terrorist attacks; and other risks and uncertainties set forth in the section entitled 'Risk Factors' and 'Cautionary Note Regarding Forward-Looking Statements' in the Company's Annual Report on Form 10-K for the year ended December 31, 2024 and Quarterly Report on Form 10-Q for the quarter ended March 31, 2025 and other documents filed by the Company from time to time with the Securities and Exchange Commission. These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Forward-looking statements speak only as of the date they are made. Readers are cautioned not to put undue reliance on forward-looking statements, and the Company assumes no obligation and does not intend to update or revise these forward-looking statements other than as required by applicable law. The Company does not give any assurance that it will achieve its in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Buzz Feed
13-07-2025
- Entertainment
- Buzz Feed
Affordable Luxury: 34 Items That Feel High-End
A CZ tennis bracelet that — according to reviewers — can pass for real-deal diamonds, especially when incorporated in a sparkly stack. A pair of Beckham Hotel Collection pillows because you haven't replaced yours in ohhh, three or four years? If they have sweat marks and unexplained stains... they're a lost cause, boo. A longline sports bra that reviewers swear by as it offers loads of support, isn't see-through, and its quality is on par with much more expensive options from Athleta and Lululemon. Le Gushe's 24K Gold Eye Patches — they stimulate collagen production, reduce dark circles and puffiness, and restore elasticity. They're less than $1 per set but they're also gold, so they feel extra luxe. A pair of $15 oval sunnies reviewers say may or may not look like a $500+ Celine pair 👀 and I'm right there with them. A bottle of Elizavecca's Collagen Coating Hair Protein Treatment which works just like a hair mask to repair your locks in five minutes flat. The Ceramide 3- and collagen-packed formula repairs all types of hair whether you've got over-processed tresses or 4c hair that's susceptible to dryness. Reviewers even say the $9 product is comparable to Olaplex No. 3! A TikTok-beloved, gold-plated paperclip necklace that reviewers say can even withstand frequent showers and trips to the beach! LivaClean Superstar pimple patches if you love the look of Starface patches, but can't stomach throwing even more money at your acne. Paying for clear skin is just the worst, isn't it?? A set of cylindrical wineglasses that'll make you feel R–I–C–H even if you're just throwing back some Two-Buck Chuck. A Simple Modern tumbler if you're looking for an option that will keep your drink cold for 24+ hours and don't really care about the name brand. 🤷♀️ It also comes in a bunch of pretty pastels and checkerboard prints, sooo it's really a no-brainer. A Baccarat Rouge 540-inspired moisturizing body wash so you can still take a moment to treat yourself even if you don't have time for an everything shower. Reviewers say the white jasmine, red currant, and sweet amber scent lasts on their skin all day and even delightfully lingers in their bathroom. Some faux-pearl statement earrings that look like they were bought from a boutique in Tahiti, but really, all you did was click "Buy Now" on Amazon and they showed up at your door in 24 hours. Some Glamnetic press-on nails which come in various lengths, shapes, and styles, and — the most important "and" there is — reviewers say they last for two+ weeks!!! Eos' Shea Butter Vanilla Cashmere body lotion — an affordable pick TikTokers are tripping over themselves to get as they swear it moisturizes and smells as good as much more expensive options from brands like Philosophy and Bath & Body Works. A dazzling cubic zirconia ring that looks *just* like the one you've seen on the hand of many a celeb and influencer... but for $10. Just keep it away from water (and maybe don't wear it to Solidcore classes if you sweat a lot), and you'll get your money's worth. A pair of lightweight legging-style joggers reviewers say are comparable to Lululemon Align Joggers — but for less than 30 bucks, so you can girl math two more Pilates classes into your weekly budget! A beaded shoulder bag you'll immediately treat as well as your firstborn child so it stays in the best condition imaginable. It's v similar to options from Staud if you love the look but simply can't afford the brand! Or a faux-leather bag that can straight up pass for Polène's Cyme. Despite its low price point, reviewers say the quality and detail — from the stitching to the hardware — is there. 👏 A tube of E.l.f. Halo Glow Liquid Filter — a $14 alternative to Charlotte Tilbury's Hollywood Flawless Filter — with a hyaluronic acid- and squalane-infused formula that beautifully blurs pores and leaves you dewy and radiant. A shower lamp so you can take your baths up a notch in the ambiance department. I don't care what anyone says, I won't hear ANY bath slander, OK?? In the eternal words of Meredith Marks, "You don't go after my marriage. You don't go after my bathtub." NYX Fat Oil Lip Drip — a TikTok-approved Dior alternative that delivers the perfect pout for under 10 bucks! It can be worn alone for a subtle look or layered over other lip products for a full glam moment. A coffee syrup dispenser set so you can feel like you're drinking a $7 cold brew from that trendy coffee shop in town when, in reality, you didn't spend a dime and made it yourself. So basically... it's a step toward being even more financially responsible. A stretchy bodycon pencil dress that'll basically feel like a second skin. Some reviewers say they were considering splurging on the Skims version until they tried this and loved it just as much! A tinted lip balm reviewers confirm is just as good as Clinique's $25 "Black Honey" — but you get two for just $9! You can stow one away for later use or even bless a friend with your bounty. Hanes Ultimate ankle socks — an affordable alternative to Aritzia's TNA line that still delivers a low crew cut and cushioned design that ensures all-day comfort. A popular checkerboard throw blanket that's garnered comparisons to Barefoot Dreams' much more expensive option. Since you're saving so much, you might as well buy one for your couch, one for your bed, one for your guest bed... A baroque-inspired mirror (with a gorg gilded frame) if you've long dreamt of owning ***that*** Anthropologie mirror but don't want to take out a second mortgage on your home in order to do so. A colorful pan — from BuzzFeed's Goodful line — that's not just cute, but has the ability to kick all of your other dented and scratched pots to the curb as it can pan fry, sauté, sear, boil, simmer, blanche, braise, poach, deep fry, stew... and more but I'll stop myself there. The Gym People's pullover fleece sweatshirt if you like the look of Lululemon's oversized scuba hoodies but can't bear to part with $118. Under $40 won't And a set of amber glass soap dispensers that look a whole lot like the ones from Aesop, but won't run you over $40 a pop. Fill 'em with your products of choice and get ready for loads of compliments for guests! MagicMinerals AirBrush Foundation — a worthy alternative to Dior's (discontinued 🪦) Airflash. This two-piece airbrush foundation and kabuki brush delivers a lightweight, buildable, flawless finish. Reviewers say a little goes a long way, too, so you don't have to worry about the spray-on formula going too fast. A floral cottagecore rug or mat that — for the first week, at least — will have you staring down at the floor in awe. Reviews compare it to Rifle Paper Co. options, but note that the price is way more palatable! A sunrise alarm clock reviewers say is super comparable to Hatch's as it offers seven nature sounds and slowly wakes you up over the course of 30 minutes by mimicking a sunrise. An Amazon Basics 6-quart Dutch oven that people compare to budget-busting versions from Le Creuset, Staub, and Lodge. Cutting costs here means you can invest more in ingredients!
Bloomberg
11-07-2025
- Business
- Bloomberg
Binance Aided Trump Crypto Firm Before Founder CZ Sought Pardon
One of the Trump family's crypto ventures has received key behind-the-scenes help from the world's largest digital-asset exchange, whose founder is a convicted felon now seeking a presidential pardon. Binance wrote the basic code to power USD1, a stablecoin launched by the Trumps' World Liberty Financial Inc., according to three people familiar with the matter. They asked not to be named because the arrangement was private. Later, Binance's founder and principal owner, Changpeng Zhao, said publicly that he had applied for a pardon. CZ, as he's known, pleaded guilty in 2023 to failing to maintain an effective anti-money-laundering program.
