Latest news with #DavidFurman
Time of India
5 days ago
- Health
- Time of India
Stanford longevity expert reverses his age by 10 years with one radical lifestyle shift
What would you do if your body was ageing faster than your birth certificate suggested? For Stanford University 's Dr. David Furman , a leading voice in the science of longevity , the answer lay not in pharmaceuticals or high-tech gadgets, but in nature — and a radical family experiment that turned their lives upside down. According to a report from The Mirror; in 2016, Furman found himself battling chronic migraines and the creeping toll of a stressful lifestyle in urban California. A pioneer of the 1000 Immunomes Project and an associate professor at Stanford, Furman decided to take a cellular deep dive into his own health. The revelations were troubling: though he was chronologically 39, his inflammatory age — a biomarker linked to disease and degeneration — clocked in at 42. As a scientist, he knew what that meant: a heightened risk of early ageing, cognitive decline, and chronic illnesses. As a father, he knew something had to change. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Buy Brass Idols - Handmade Brass Statues for Home & Gifting Luxeartisanship Buy Now Undo Life in the Woods: From Headaches to Healing Furman packed up his life, wife, and two children and moved into a minimalist two-bedroom cabin nestled in Northern California's wilderness. Chairs were banned, industrial cleaners were out, and electricity usage was pared back to the bare minimum. By 7:30 every evening, all overhead lights were turned off and the family lived by candlelight, eschewing screens and devices in favour of analog living. Their daily routine included foraging, organic eating , and fitness rooted in nature. Furman, for instance, began each day with 10 to 15 pull-ups, caught fresh fish from a nearby creek, and snacked on hand-picked berries. Meals featured nutrient-dense, unprocessed foods — raspberries, broccoli, and wild greens became the norm. The lifestyle wasn't just a retreat — it was a rigorous biological experiment, and Furman was both subject and scientist. The Stunning Results: Turning Back the Clock Three years later, Furman ran the same cellular test that once gave him a wake-up call. The results were staggering: his inflammatory age had dropped to 32. In other words, he had turned back the clock by a full decade. Gone were the migraines, replaced by sharper focus, sustained energy, and what Furman describes as 'a lot of productivity.' His academic output surged — he published three research papers in a single year, and felt, in his own words, 'better than ever.' Science Says: Nature Really Does Heal Furman's forest-bound lifestyle wasn't just a personal success story; it echoed a growing body of global research. A 2019 study on 'forest bathing' revealed that time spent in green spaces significantly improves health outcomes and mental wellbeing — even for those with chronic diseases or disabilities. The magic number? Just two hours a week in nature, according to researchers from the University of Exeter. These sessions didn't need to be in remote woodlands — urban parks and beaches had similar effects. What mattered was immersion and consistency. Dr. Mathew White, a wellness researcher at Exeter, underscored the findings: 'It didn't matter where in nature you went... 60 or 90 minutes didn't seem to have the same benefits. It really needed to be at least two hours a week.' Furman's journey is both inspiring and instructive — a testament to the power of nature, simplicity, and conscious living. While not everyone can relocate to the woods, his story invites us to rethink the architecture of our daily routines. Could reversing ageing be as simple as switching off your phone, walking in a park, and eating what the earth gives you? For Dr. David Furman, it wasn't a theory — it was his life. And it changed everything.
Associated Press
28-05-2025
- Business
- Associated Press
Circulate Health Publishes Results of Multiomics Study Demonstrating Impact of Therapeutic Plasma Exchange on Biological Age in Aging Cell
First-of-its kind trial shows that therapeutic plasma exchange combined with intravenous immunoglobulin reduced biological age on average by 2.6 years, as measured by multi-omics biomarkers NOVATO, Calif., May 28, 2025 /PRNewswire/ -- Circulate Health, the company dedicated to harnessing the potential of therapeutic plasma exchange (TPE) to advance human healthspan and lifespan, today announces the publication of a single blind, human clinical trial in Aging Cell. This groundbreaking study, led by researchers from Circulate and the Buck Institute for Research on Aging provides promising early data on the impact of TPE on biological age, supporting its potential for new disease and longevity applications. 'Unfortunately, most so-called 'longevity interventions' lack proven effectiveness in humans. By conducting clinical trials, we aim to change that—this study marks the first step in demonstrating that plasma exchange can significantly improve key mechanisms of biological aging,' commented Dr. David Furman, senior author of the Aging Cell paper. Therapeutic plasma exchange is a procedure that separates, removes, and replaces patient plasma to treat certain diseases. Multi-omics Analysis Reveals Biomarkers that Contribute to Biological Age Rejuvenation in Response to Therapeutic Plasma Exchange, investigated how TPE impacts biomarkers associated with biological age, including changes across the epigenome, proteome, metabolome, glycome, and immune system, alongside physical measures like balance and strength. Research participants were assigned one of four different treatment groups: 1) biweekly TPE, 2) biweekly TPE with intravenous immunoglobulin (IVIG) 3) monthly TPE or 4) a control group. The study found: 'This is the first interventional multi-omics study to examine the effectiveness of therapeutic plasma exchange modalities,' said Brad Younggren, MD, CEO and Co-founder of Circulate. 'Our findings show that plasma exchange and intravenous immunoglobulin are a powerful tool for biological age rejuvenation and provide compelling evidence that targeted plasma interventions can impact age-related molecular changes.' 'In this study, we examined thousands of molecular signatures to pinpoint key drivers of rejuvenation. Our characterization builds a better understanding of which baseline biomarkers are predictive of treatment response and lays a foundation upon which we can build personalized intervention plans for patients in the future,' said Eric Verdin, MD, President and CEO of the Buck Institute and Co-founder of Circulate. 'We are excited to expand our research to larger populations, increase access to these treatments for eligible patients, and continue to identify areas of unmet need where these therapies can make a meaningful difference.' Clinicians can learn more about Circulate at About Circulate Health Backed by Khosla Ventures, Circulate Health is pioneering technologies to reverse aging and improve health outcomes. About Buck Institute Our success will ultimately change healthcare. At the Buck, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede the ways in which we age. An independent, nonprofit institution, our goal is to increase human healthspan, or the healthy years of life. Globally recognized as the pioneer and leader in efforts to target aging, the number one risk factor serious diseases including Alzheimer's, Parkinson's, cancer, macular degeneration, heart disease, and diabetes, the Buck wants to help people live better longer. Learn more at: View original content: SOURCE Circulate Health
Daily Mail
27-05-2025
- Health
- Daily Mail
A longevity expert says he lowered his biological age by moving his entire family to the forest
A longevity expert has revealed how he managed to de-age himself by a decade simply by changing his address. Ten years ago, Dr David Furman, an associate professor and head of Stanford University's 1000 Immunomes Project, was living in a California city where he suffered migraines and relied on ibuprofen to dampen the pain. Claiming his life was 'pretty stressful', the anti-aging expert believed his body was aging in 'hyperdrive' and he knew his constant headaches were a sign of something more sinister. So, he decided to check if his theory was true and tested his blood for inflammatory markers. Much to his shock, he found while his biological age was 39, his body had the 'inflammatory age' of a 42-year-old man. Disappointed in his results, the scientist knew if he continued to live his life as it was, he would be more susceptible to premature aging, chronic conditions like diabetes and heart disease, as well as mental decline. To prevent this, Dr Furman decided to move to the woods in Southern California with his wife and two kids to improve their health. And with a few lifestyle and dietary changes, in the three years the family lived in the woods, the professor managed to de-age his body by 10 years. Reflecting on his initial diagnosis, Dr Furman told Business Insider: 'I freaked out. Any species that you put in a new environment will develop inflammation as a response to something foreign; we do not escape that reality.' In 2016, the expert and his family moved to a two-bedroom cabin close to a creek in parts of a nearby forest in the San Gregorio area of Northern California that was about a half-hour drive from Stanford. Their house had no chairs, no plastics and no industrial cleaning products. The couple also stopped using all electronics and turned off bright overhead lights at 7.30pm every night, instead lighting candles to start winding down for bed. Dr Furman recalled: 'We haven't evolved looking at a screen and having an electrical light and sitting in a chair.' Several studies suggest excessive screen time, particularly from phones, tablets, and computers can negatively impact cognitive function, decrease physical activity and damage retinal cells, as well as disrupt sleep. A 2021 Springer Nature study found increased use of screens among adults between 18 to 25 years old may harm learning, memory and mental health, as well as increase the risk of early neurodegeneration. A 2024 study in the Journal of the American Medical Directors Association found adults who watched television for five hours or more per day had a 28 percent increased risk of developing brain-related diseases such as Parkinson's disease. Dr Furman would also complete a daily workout of 10 to 15 pull-ups before work every day, and on his days off, he would play in the dirt with his kids, fish for salmon in the creek and forage for berries. The anti-aging expert would also pack healthy lunches of salmon lettuce wraps with a side of blueberries for work - all of which have been proven to be full of magnesium, omega-3 and antioxidants that can help improve brain health. Dr Furman also opted to rely on fresh, organic foods like raspberries and broccoli to 'feed the microbiome' rather than take vitamins and mineral supplements - and a balanced microbiome has been associated with improved mental health and a decreased risk of cancer. Raspberries are known to be a great source of antioxidants, fiber, and vitamin C while broccoli is a rich source of fiber, vitamin C, vitamin K and sulforaphane - a plant compound with potential cancer-fighting properties. Dr Furman reflected: 'I was feeling great, very energetic, and no more headaches.' His health wasn't the only thing that improved. Dr Furman told Business Insider: 'I was sharp, better than ever. Just a lot of productivity.' He had managed to publish three papers within a year - which was times more than his normal amount. After spending three years in the forest, Dr Furman decided to once again check his blood for inflammatory markers and see if his health had improved. Much to his surprise, the now 42-year-old scientist had managed to bring down his 'inflammatory age' to 32 - a whole decade younger than his actual biological age. And he may have the forest to thank. A 2019 study found 'forest bathing' -immersing yourself in nature - for at least 120 minutes every seven days promotes wellbeing. The research was carried out by the University of Exeter and it analyzed two-year's worth of data from more than 20,000 people who took part in the Natural England's Monitor of Engagement with the Natural Environment Survey. Results - published in the journal Scientific Reports - revealed those who spent at least two hours a week in nature were more likely to report being in good health. This is compared to those who did not venture into the outdoors at all on a typical week. The study's forest bathers also reported having a higher psychological wellbeing. Even those with chronic illnesses or disabilities benefited from time outside. The scientists said two hours a week is a 'realistic target' for most, particularly when it can be broken up into several short visits over the seven days. Dr Mathew White, an environmental psychologist and senior health and wellness lecturer at the University of Exeter, said: 'You could go for a walk for two hours on a Sunday or you could go for four lots of 30 minute [walks] during lunchtimes during the week. 'And it didn't matter where in nature you went. It could be on the beach, it could be in an urban park or it could be in a woodland. 'Doing 60 or 90 minutes didn't seem to have the same benefits at all. It really needed to be at least two hours a week.' The results applied to both men and women, as well as across adults of all ages, occupations and ethnicities.
Business Insider
24-05-2025
- Entertainment
- Business Insider
Grilling season is here. Chefs share tips to make the best burgers.
Welcome back to our Saturday edition! Are you headed to the movie theater this weekend to see Tom Cruise's next big flick, "Mission: Impossible — The Final Reckoning"? Find out why he's had such staying power. Hint: It rhymes with punts. On the agenda: Living in the forest for four years shaved a decade off a researcher's biological age. Rich Americans are booking fancy vacations. Everyone else is cutting back. Morgan Wallen is the man of the moment because of his controversies, not in spite of them. A week on Mexico's "Happy Coast," the hidden getaway of the wealthy. But first: It's cookout time. If this was forwarded to you, sign up here. Download Business Insider's app here. This week's dispatch It's time to sizzle and serve Summer, is that you? :squints: With Memorial Day on Monday serving as the unofficial kick-off for summer, it's my favorite time of the year — grilling season. Get out the burgers. Get out the hot dogs. And if you'd rather not eat meat, get out the vegetables. Luckily for you, BI's Lifestyle team has been speaking with various chefs for tips on how to ensure people will be coming back to your grill asking for more. Chef Alissa Fitzgerald tells BI that a good burger starts with the kind of beef you buy. Try to aim for beef with " 80% meat and 20% fat," allow them to thaw completely, and don't season them too early. "Right before placing it on the grill, take a large pinch of kosher salt and gently cover the outside of the patty with a thin layer," she suggests. "Add the burger salt-side down on the grill and sprinkle some on the other side." If you're putting other types of meat on the grill, however, like steaks, you'll want to season them "a few hours before you plan on cooking it and let it sit in the fridge," Chef Marcus Jacobs tells BI. Meanwhile, when grilling chicken, Jacobs suggests creating a "blend of salt, white and black pepper, paprika, coriander, and several different types of chilies." No matter how you season or what you're throwing on the grill, check out the chefs' other tips to make sure you're not the talk of the neighborhood for the wrong reason. Touching grass David Furman When David Furman discovered his body was prematurely aging because of stress, he and his family moved to a one-room cabin in the woods to reset. Furman changed what they ate and how he exercised, and scaled back use of electronics. To his delight, the experiment worked: It dramatically improved his longevity and energy. He continues to reap the benefits now, even after leaving the forest. Plus, his family loved the lifestyle. Travel is for the rich now Almost half of summer travelers this year make over $100,000, according to a Deloitte survey. The wealth gap is growing, and middle-income vacationers are either staying home or opting for more budget-friendly trips. Even as demand wavers, luxury travel is booming. New accommodations are under construction, and "luxury" short-term rentals are increasing in price faster than other listings. But the stark divide may not last forever. Morgan Wallen's country There's nothing sonically special about Morgan Wallen's music, and he has a habit of attracting controversy. Still, in the wake of scandals involving slurs and disorderly conduct, Wallen is more popular than ever. That's because Wallen's messiness is a key part of his brand, writes BI's Callie Ahlgrim. Fans see his scandals as proof of his authenticity, and he embodies an idea of freedom. Why it pays to be the problem. A Happy Coast hideaway A 155-mile stretch of Mexico's Pacific coast is a quiet vacation hot spot for the ultrawealthy. Costalegre, Spanish for "Happy Coast," is practically impossible to reach — for those without a private jet, at least. BI's Monica Humphries spent a week resort-hopping in Costalegre. Each had a different appeal, from the neighborhood feel and star-studded history at Careyes to the ATVs and private beaches at Las Alamandas. Meet luxury and nature. What we're watching this weekend "Sirens": Julianne Moore, "The White Lotus" actor Meghann Fahy, and "House of the Dragon" standout Milly Alcock all star in Netflix's new dark comedy set in a beachside town. "The Last of Us": Season two of HBO's TV show adaptation of the popular video game series ends this weekend. "Nine Perfect Strangers": Nicole Kidman returns as a wellness guru in season two of the Hulu series, this time set in the Austrian Alps. See the full list Deals we love Memorial Day savings: Mattresses are almost always on sale, but our deal experts know that Memorial Day is when we see the steepest discounts. Here are the best mattress deals for the holiday weekend. Business (Insider) casual: Our men's style editors are here to help you look sharp at the office without feeling stiff. Check out our brand-new guide to the best men's business casual clothes for work. Le Creuset vs. Staub: Our kitchen experts hate to break it to you, but there's a reason the more expensive option is better. Here's why we recommend Le Creuset. More of this week's top reads: I stayed at a luxurious resort in Barbados with my young daughter. From the private pool to the stunning beach, our stay was nearly perfect. Keke Palmer said she didn't feel adequately paid in Hollywood until Jordan Peele's 'Nope' — two decades into her career. Four sandal trends that are in this summer and four that are out, according to stylists and designers. The patent behind a $182 cult-favorite skincare product recently expired. So where are all the dupes? I visited the most expensive city in Utah and spotted five signs of over-the-top wealth and luxury. Beyoncé and Sabrina Carpenter's choreographer shares how she gets her clients so fit they can sing and dance — in just 12 weeks. Five style mistakes a menswear designer wishes you would stop making. A 56-year-old personal trainer on how to build muscle after 40 — with rucking, body weight exercises, and short workouts. I visited Universal's new theme park, Epic Universe. I see why some people wouldn't like it, but I'd happily go back. The BI Today team: Dan DeFrancesco, deputy editor and anchor, in New York City. Grace Lett, editor, in New York. Lisa Ryan, executive editor, in New York. Amanda Yen, associate editor, in New York. Elizabeth Casolo, fellow, in Chicago.
