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Cellares and Mitsui Fudosan Announce the First IDMO Smart Factory for Commercial-Scale Cell Therapy Manufacturing in Japan
Cellares and Mitsui Fudosan Announce the First IDMO Smart Factory for Commercial-Scale Cell Therapy Manufacturing in Japan

Business Wire

time7 days ago

  • Business
  • Business Wire

Cellares and Mitsui Fudosan Announce the First IDMO Smart Factory for Commercial-Scale Cell Therapy Manufacturing in Japan

SOUTH SAN FRANCISCO, Calif. & TOKYO--(BUSINESS WIRE)-- Cellares, a pioneer in automated cell therapy manufacturing, in collaboration with Mitsui Fudosan, announces the establishment of Japan's first next-gen commercial production site for CAR-T cell therapies. The facility is under construction in Kashiwa City, a vibrant urban center located approximately 30 kilometers northeast of central Tokyo in Chiba Prefecture. As part of the extensive Tokyo metropolitan region, Kashiwa serves as a booming biotech hub. This groundbreaking Integrated Development and Manufacturing Organization (IDMO) Smart Factory is expected to provide employment to 350 people while enabling scalable and cost-effective cell therapy manufacturing, addressing an urgent need for patients in Japan and neighboring regions. The facility, set to open in partnership with Mitsui Fudosan, will utilize Cellares' state-of-the-art technology platforms, the Cell Shuttle™ and Cell Q™, to automate cell therapy manufacturing and quality control. The technology reduces batch prices by up to 50% and eliminates the manufacturing bottlenecks faced by conventional CDMOs that use manual processes. Additionally, the entire Smart Factory will be integrated and optimized to eliminate any downstream bottlenecks as well. 'Cellares' new facility in Kashiwa City will enable our pharma clients to supply Japan from Japan. Manufacturing cell therapies locally simplifies cold chain logistics, accelerates vein-to-vein time and reduces cost,' said Fabian Gerlinghaus, CEO and Co-Founder of Cellares. 'Our Japanese IDMO Smart Factory is part of a broader strategy to be a global manufacturing partner for our clients and meet the total patient demand for cell therapies around the world.' The new site's impact extends beyond patient care. By accelerating the availability of CAR-T treatments, this initiative has the potential to help advance the development and approval of CAR-T therapeutics in Japan. Once the IDMO Smart Factory is online, technical transfers between Cellares facilities in other regions are expected to be a seamless, rapid, software-enabled process. Thanks to fully automated processes on standardized technologies, tech transfer can now happen at digital speed. Dr. Toshihiko Doi, the Chairperson of the Kashiwa-no-ha Life Science Committee, shared, 'For cancer patients in Japan, the establishment of this facility provides access to cutting-edge therapies that can make a critical difference in their fight against diseases. It marks a significant step toward eliminating the drug delivery lag time that has been a challenge for rare disease and oncology treatments.' Mitsui Fudosan's robust network in Japan's life sciences industry has been instrumental in enabling this collaboration, ensuring the smooth dissemination of information to the pharmaceutical industry, government agencies, and the broader healthcare community. This announcement represents Cellares' commitment to expanding its footprint in Japan, paving the way for further collaborations and innovations. For more information, visit About Cellares Cellares is the first Integrated Development and Manufacturing Organization (IDMO) and takes an Industry 4.0 approach to mass manufacturing the living drugs of the 21st century. The company is developing and operating integrated technologies for cell therapy manufacturing to accelerate access to life-saving cell therapies. The company's Cell Shuttle™ integrates all the technologies required for the entire manufacturing process in a flexible and high-throughput platform that delivers end-to-end automation. While the Cell Shuttle automates cell therapy manufacturing, the Cell Q™ automates quality control at high throughput, both for in-process and release QC. Cell Shuttles™ and Cell Qs™ will be deployed in Cellares' Smart Factories around the world, enabling each Smart Factory to produce 10 times as many cell therapy batches as a conventional CDMO with the same facility size and headcount. Partnering with Cellares enables academic medical centers, biotechnology companies, and pharmaceutical companies to accelerate cell therapy development and scale out manufacturing, lower process failure rates, lower manufacturing costs, and meet global patient demand. The company is headquartered in South San Francisco, California with its first commercial-scale IDMO Smart Factory in Bridgewater, New Jersey. Cellares is building a global network of IDMO Smart Factories, with additional facilities under construction in Europe and Japan. The company is backed by world-class investors and has raised over $355 million in financing. For more information about Cellares, please visit About Mitsui Fudosan Co. Mitsui Fudosan is working to create new industries during this time of change in society and the economy. As a "Platformer," the company provides "Places" and "Communities" that bring together the ideas of companies, society, and individuals. In April 2024, it launched a Group's New Long-Term Vision, setting a strategy to explore areas beyond real estate. To support this, Innovation Promoting Division was established to drive innovation and help create new industries. At Kashiwa-no-ha Smart City, Mitsui Fudosan works with the public, private, and academic sectors to create a community where people can live healthy lives and where new life science industries can grow.

Andhra Pradesh government launched ‘One Family, One Entrepreneur', to foster a culture of entrepreneurship in every household, says MSME Minister
Andhra Pradesh government launched ‘One Family, One Entrepreneur', to foster a culture of entrepreneurship in every household, says MSME Minister

The Hindu

time24-05-2025

  • Business
  • The Hindu

Andhra Pradesh government launched ‘One Family, One Entrepreneur', to foster a culture of entrepreneurship in every household, says MSME Minister

Minister for Micro, Small and Medium Enterprises (MSME) Kondapalli Srinivas launched Confederation of Indian Industry (CII) Andhra Pradesh Entrepreneurs Development Forum and CII Tirupati Entrepreneurs Development Forum in Tirupati on Saturday. He also unveiled the CII Project 'Abhivrudhi Padham lo Swarna Andhra Pradesh Nuthana Prayanam.' Addressing the gathering, he said, 'The A.P. government has launched the flagship programme 'One Family, One Entrepreneur', with a mission to foster a culture of entrepreneurship in every household. This initiative plays a pivotal role in the development of MSMEs as drivers of self-reliance, innovation and job creation.' The Minister further said, 'In a landmark move under Phase 1, the Chief Minister has inaugurated MSME Parks and Flatted Factory Complexes in 11 Assembly constituencies and the foundation stones were laid in 39 other constituencies at Narempeta village in Atmakur mandal of SPSR Nellore district on 1st May, 2025.' 'In order to sustain the annual growth rate exceeding 15% and achieving $2.4-trillion economy, as mandated under Swarna Andhra@2047, the Chief Minister has reiterated the need for establishment of at least one MSME Park in each constituency for extending infrastructural support by developing plug and play facilities, approach road and power, which would reduce the initial capital costs,' he added. Tirupati District Collector S. Venkateswar said, 'At present, the growth in Tirupati is 18% and there are more than 15,000 MSMEs in the district generating 2.5 lakh employment which is more than the large industries in the district.' S. Narendra Kumar, vice-chairman, CII Andhra Pradesh, said, 'India must create 7.85 million non-farm sector jobs annually by 2030. Microenterprises, being the engine of job growth in dynamic economies, are vital to meeting this challenge. A.P.'s focus on mass entrepreneurship is aligned with national employment goals.' CII project 'The project titled 'Abhivruddhi Patham Lo Swarna Andhra Pradesh' (A new journey towards development) is the first major step by the CII as a part of its Centre of Excellence on Employment and Livelihood (CEL). This has been officially launched with the support from the State government and Volvo Group Trust,' he informed.

Obituary: David Johansen, musician
Obituary: David Johansen, musician

Otago Daily Times

time18-05-2025

  • Entertainment
  • Otago Daily Times

Obituary: David Johansen, musician

American singer, songwriter and actor, David Johansen, poses for a portrait circa 1980 at The Old Waldorf in San Francisco, California. Inspired by British glam rock and inspirational to the emergence of punk rock, David Johansen was the face of influential United States band the New York Dolls. A New York native, Johansen gravitated to Andy Warhol's Factory scene. Having cut his teeth in several bands and the theatre industry, Johansen's break came in 1971 when the Dolls then singer Johnny Thunders opted to stick to his bass. Their raucous lifestyle, androgynous look and wild-eyed hard rock earned them a cult following but not commercial success. The band's last show was in December 1976, just before the many bands who had taken their cue from the Dolls look and sound started to make it big. Johansen went solo, with limited success, although his blues/swing alter ego Buster Poindexter did trouble the lower reaches of the charts and one single, a cover of Hot Hot Hot, made the US top 20. The surviving New York Dolls reformed in 2004 for a London festival, touring until 2011. Johansen was also an accomplished actor whose credits included appearances in the films Scrooged and Freejack, as well as TV shows Oz and The Equaliser. David Johansen died on February 28 aged 75. — APL/agencies

Chief Minister Chandrababu Naidu will launch 10 MSME Parks, lay stone for 40 more in A.P. on May 1, says Kondapalli Srinivas
Chief Minister Chandrababu Naidu will launch 10 MSME Parks, lay stone for 40 more in A.P. on May 1, says Kondapalli Srinivas

The Hindu

time29-04-2025

  • Business
  • The Hindu

Chief Minister Chandrababu Naidu will launch 10 MSME Parks, lay stone for 40 more in A.P. on May 1, says Kondapalli Srinivas

The Government of Andhra Pradesh is all set to inaugurate 10 MSME Parks and lay foundation for another 40 on May 1, 2025. 'The MSME Parks in Anakapalli, Pileru and other areas, which are ready in all aspects, will be dedicated to the people by Chief Minister N. Chandrababu Naidu at the Atmakur MSME Park in Nellore district. He will also lay the foundation for construction of the proposed 40 parks,' Kondapalli Srinivas, Minister for MSME, told The Hindu here on Tuesday. Of the ambitious target of constructing 175 MSME Parks in each Assembly constituency, the government completed 10, he said. Besides laying the stone for 40 more parks, it was proposed to commence work on 45 additional parks in six months and take up work on the remaining parks after one year. 'The government aims to complete all the parks in three years,' Mr. Srinivas said. 'Interested persons may apply for allotment of land in the 10 parks from May 1,' Mr. Srinivas said. The government was planning to designate sectoral MSME Parks, among the 175, depending on the demand and resources available in the respective areas. At the same time, he said the government would encourage private MSME Parks as well, he said. The Minister said the government planned to construct at least one Flatted Factory Complex (FFC) in each constituency, which would be of help to the micro industries having an investment of about ₹20 lakh. 'Both the MSMEs and FFCs will nourish the economy by creating employment and industrial opportunities,' Mr. Srinivas said. The government negotiated with the bankers to provide ₹1.28 lakh crore loan to the MSMEs for the 2025-26 Financial Year, he said, adding that it was about 48% higher than the previous year's loan limit of ₹87,000 crore for the sector. He said the bankers accepted the proposal of the government at the State Level Bankers' Committee (SLBC) meeting on Tuesday.

Full 2025 Galway Folk Festival line-up revealed featuring Lloyd Cole, Martha Wainwright and many more
Full 2025 Galway Folk Festival line-up revealed featuring Lloyd Cole, Martha Wainwright and many more

Irish Independent

time25-04-2025

  • Entertainment
  • Irish Independent

Full 2025 Galway Folk Festival line-up revealed featuring Lloyd Cole, Martha Wainwright and many more

A spokesperson for the festival promises an 'unforgettable experience' highlighted by two 'must-see headline performances'. According to the spokesperson: 'Renowned singer-songwriter Lloyd Cole will perform an intimate, Irish festival-exclusive show at the Town Hall Theatre. "Meanwhile, Montreal's celebrated singer Martha Wainwright will mark the 20th anniversary of her ground-breaking debut album with a full live performance, including hits like the iconic Bloody Mother Fucking A**hole, Factory, and When The Day Is Short. "These powerful songs, which established Martha as an undeniable talent, continue to resonate with audiences worldwide.' Other note-worthy acts featured on this years' line-up include: Fionn Regan, The Scratch, KÍLA, Seanchoíche, Ultan Conlon, Laura Duff, The Half Room, Tadhg Williams, and many more. In addition to the ticketed shows, festival-goers can enjoy free daytime events over the weekend. Cuppa Tea TV returns with The Market Stage, while Culture Vultures, hosted by Tony Clayton-Lea, will feature engaging conversations with special guests. The Youth in Music stage will showcase the rising stars of folk, while The Little Room of Folk and Westend Sessions offer intimate performances and vibrant sessions.' Speaking about the festival's return for a fourth edition, festival directors Gary Monroe and Peter O'Sullivan said: 'We're excited to return for our fourth year of celebrating folk, roots, and traditional music. The support for the festival has been amazing, with ticket sales from all over the world. This year is our biggest festival to date and we're delighted to expand the free weekend daytime events which are family friendly and will have something for everyone from pop up shows to food stalls and stalls from our friends at the Tiny Traders Village.' Tickets for all events can be purchased through the festival's website.

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