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Medscape
16-07-2025
- Health
- Medscape
New Data on Postoperative Delirium a ‘Call to Action'
Postoperative delirium following noncardiac surgery was linked to a 3.5-fold higher risk for death or major complications, but low-cost interventions focusing on avoiding patient disturbances can mitigate those negative outcomes, a new landmark study showed. An estimated one in 30 patients in the study experienced postoperative delirium, with high levels of variation in incidence rates among hospitals. Researchers said the findings are a 'call to action' to health providers to proactively manage the risks of postoperative delirium. 'This study is not just about identifying a problem, but it's also about giving people a sense of the scope of the problem. When you do that, it kind of energizes people to say okay, let's go out and see if we can do something about this,' principal investigator Laurent Glance, MD, professor and vice-chair for research in the Department of Anesthesiology at the University of Rochester School of Medicine (URMC), Rochester, New York, told Medscape Medical News . The study is the largest to date to examine the clinical implications of postoperative delirium on a national scale and was published online on July 8 in JAMA Network Open . Acute Brain Failure Postoperative delirium was once thought to be a minor and temporary complication. However, that has changed over the past decade. The American Geriatrics Society, which describes postoperative delirium as 'acute brain failure,' recommends the condition be treated as a medical emergency that requires rapid diagnosis and treatment. The cost of managing the condition runs roughly $26 billion to $42 billion in the US each year, and recent studies have linked postoperative delirium to the development of dementia in older adults. For this study, investigators used Medicare claims data from 2017 to 2020 of more than 5.5 million adults over the age of 65 years (mean age, 74.7; 57.2% women). Postoperative delirium was identified based on ICD-10 codes. Postoperative delirium was identified in 3.6% of cases. Patients with delirium were more likely to be male and have comorbidities, including cerebrovascular disease, heart failure, and dementia. Compared to patients without delirium, those with the condition were significantly more likely to experience death or major complications (adjusted odds ratio [aOR], 3.47), non-home discharges (aOR, 3.96) and 30-day mortality (aOR, 2.77; P < .001 for all). Findings were similar even after adjusting for hospital characteristics and excluded the patients admitted in 2020 during the height of the COVID-19 pandemic. 'Opportunity for Improvement' Investigators also found a nearly threefold variation in the rates of postoperative delirium among the 3169 hospitals included in the study. 'When you see that level of variation, what it tells you is that there is an opportunity for improvement,' Glance said. In fact, researchers noted that prior work found that postoperative delirium is preventable in up to 40% of cases. '[Postoperative delirium] is not something that's guaranteed because you're older or because you have multiple medical problems,' lead author Heather Lander, MD and assistant professor in the Department of Anesthesiology and Perioperative Medicine at URMC, Rochester, New York, told Medscape Medical News . 'This is something that we as a healthcare system can identify early,' she added. Variability among institutions could also be due to differences in coding accuracy and delirium screening, instead of reflecting true differences in hospital performance, the investigators wrote. Delirium Often Underreported The incidence of postoperative delirium reported in the study is markedly lower than previously reported rates of roughly 20% for noncardiac surgery patients. The researchers noted that incidence of postoperative delirium is known to be underreported in Medicare claims data. Postoperative delirium can be miscoded as other conditions for financial incentives or go undetected by clinicians, particularly for hypoactive delirium where patients may not show typical symptoms of restlessness or disorientation. Commenting on the finding for Medscape Medical News , Donna Fick, PhD, distinguished professor at Pennsylvania State University College of Nursing, University Park, Pennsylvania, noted that the miscoding of postoperative delirium might underrepresent affected patients in the study. 'When you use ICD-10 codes, claims or administrative data to examine this problem, you're dependent on clinicians coding the delirium, and we know that that's grossly under representative,' said Fick, who was not part of the study. Given the poor health outcomes identified and extrapolated onto a likely higher number of patients affected, this is a 'really important study' to represent delirium impacts on a national scale, Fick added. The authors also did a good job of controlling for important variables, including economic and social determinants of health as well as frailty and comorbidity, she said. Reducing Delirium Rates Investigators also found that patients undergoing surgery in hospitals with a higher rate of postoperative delirium had 1.5-fold higher odds of experiencing it compared to hospitals with lower rates. However, 'the inference from that finding has to be very carefully interpreted,' Esther Oh, MD, PhD, professor and associate director of the Johns Hopkins Memory and Alzheimer's Treatment Center, Baltimore, told Medscape Medical News. Some hospitals that are referral-based will take sicker patients compared to smaller hospitals, and those that have a delirium screening policy will find more delirium as a direct result, Oh noted. Both Oh and Fick supported several low-cost, nonpharmacologic interventions to reduce delirium risk that Glance and colleagues recommended in the study, including avoiding sleep disturbance, sensory support and enhanced screening for at-risk patients. 'It would be our hope eventually that postoperative delirium will be one of the quality metrics that will be used by CMS to evaluate hospital quality,' Glance said. In doing so, public reporting will enhance transparency, awareness and accountability of this issue and hospitals might up their efforts to reduce the rates of postoperative delirium, he added.
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Business Standard
15-07-2025
- Business
- Business Standard
InMobi expects Glance biz to catch up with advertising revenue in 2 years
To be sure, Glance already operates a lock-screen content and a product discovery platform. Besides this, the consumer business also includes Roposo, Nostra, and 1Weather with 350 mn active users premium Avik Das Bengaluru Listen to This Article Global mobile advertising firm InMobi Group expects its subsidiary Glance to match its core advertising business in revenue within the next two years, despite currently contributing only a third. The company is banking on the rapid adoption of its newly launched Glance AI platform globally, with special focus on the US. The app is an AI-native commerce platform powered by proprietary AI models, which is expected to change the way people shop and reshape how intelligence drives decision-making. 'Both businesses will be of equal size in the next 24 months, and Glance will also turn profitable next year,' Naveen Tewari,


Time of India
03-07-2025
- Business
- Time of India
Glance appoints Amit Bansal to spearhead the future of AI led commerce with Roposo
Glance, the consumer technology company pioneering AI native experiences, today announced the appointment of Amit Bansal as Senior Vice President & General Manager of Roposo, its next generation commerce platform that empowers individuals to launch and scale personalized, content-driven leadership appointment comes as Glance prepares to accelerate its vision with Glance AI, a transformative AI commerce platform built to change the way the world shops. By harnessing generative AI, real-time content orchestration, and immersive visual intelligence, Glance AI offers a discovery first experience that connects users to products through inspiration, not just intent. In his role, Amit will be responsible to scale Roposo into a future-ready, AI led commerce ecosystem that merges content and communities, enabling millions of digital storefronts to thrive in a rapidly evolving market. He will also work closely with Glance and InMobi's broader global platforms to drive innovation and market expansion. 'India is at an inflection point, and Glance is building what comes next.' said Naveen Tewari, Founder & CEO, InMobi & Glance. 'As content, AI, and commerce converge, a whole new paradigm of discovery led shopping is emerging; one that's immersive, intelligent, and deeply personal. Amit has a rare ability to build at scale with bold vision, and we're excited to have him lead this pivotal next chapter for Roposo.' Amit brings over two decades of experience in shaping India's digital commerce landscape. Most recently, as Founder & CEO of Solv, he built one of the country's leading B2B commerce platforms, serving over 400,000 MSMEs and achieving $650M in GMV and $24M in ARR, all on a capital efficient, zero inventory model. Under his leadership, Solv fostered a high trust, performance driven culture with best-in-class team engagement and leadership scores. Prior to that, Amit played critical roles in shaping the country's digital journey, from helping Flipkart scale into a $15B enterprise, to leading rapid expansion at Reliance Retail, and building Ezmall from the ground up. His work has consistently focused on unlocking access, opportunity, and scale for businesses and consumers alike. 'Glance isn't just building a product; it's architecting a new digital economy.' said Amit Bansal, SVP & GM, Roposo. 'We're shifting from transactional commerce to a world where discovery, content and AI define how people shop and how entrepreneurs grow. Roposo has the potential to power millions of vibrant storefronts, and I'm excited to lead its journey in shaping the future of commerce.'


Time of India
01-07-2025
- Business
- Time of India
Glance appoints Amit Bansal to spearhead the future of AI led commerce with Roposo
Glance , the consumer technology company pioneering AI native experiences, has announced the appointment of Amit Bansal as senior vice president and general manager of Roposo , its next generation commerce platform that empowers individuals to launch and scale personalised, content-driven storefronts. This leadership appointment comes as Glance prepares to accelerate its vision with Glance AI , a transformative AI commerce platform built to change the way the world shops. By harnessing generative AI, real-time content orchestration, and immersive visual intelligence, Glance AI offers a discovery first experience that connects users to products through inspiration, not just intent. In his role, Bansal will be responsible to scale Roposo into a future-ready, AI led commerce ecosystem that merges content and communities, enabling millions of digital storefronts to thrive in a rapidly evolving market. He will also work closely with Glance and InMobi 's broader global platforms to drive innovation and market expansion. 'India is at an inflection point, and Glance is building what comes next,' said Naveen Tewari, founder and chief executive officer, InMobi and Glance. 'As content, AI, and commerce converge, a whole new paradigm of discovery led shopping is emerging; one that's immersive, intelligent, and deeply personal. Amit has a rare ability to build at scale with bold vision, and we're excited to have him lead this pivotal next chapter for Roposo.' Bansal brings over two decades of experience in shaping India's digital commerce landscape. Most recently, as founder and chief executive officer of Solv, he built one of the country's leading B2B commerce platforms. Prior to that, Bansal played critical roles in shaping the country's digital journey, from helping Flipkart scale into a USD 15B enterprise, to leading rapid expansion at Reliance Retail, and building Ezmall from the ground up. His work has consistently focused on unlocking access, opportunity, and scale for businesses and consumers alike. 'Glance isn't just building a product; it's architecting a new digital economy,' said Bansal. 'We're shifting from transactional commerce to a world where discovery, content and AI define how people shop and how entrepreneurs grow. Roposo has the potential to power millions of vibrant storefronts, and I'm excited to lead its journey in shaping the future of commerce.'


Time of India
25-06-2025
- Business
- Time of India
InMobi appoints Kunal Nagpal as chief business officer overseeing InMobi's ad businesses
InMobi has announced the appointment of Kunal Nagpal to the role of chief business officer , with responsibility over InMobi's advertising businesses . This newly created position marks a pivotal step in enhancing the company's advertising initiatives across InMobi's diverse portfolio, including Glance AI , an immersive generative AI commerce platform, along with InMobi Global Exchange and InMobi DSP . Armed with a new unified Go-To-Market (GTM) strategy and poised to elevate customer and partner experiences across various regions, InMobi boasts a cohesive, dynamic brand identity in an ever-evolving advertising landscape. 'We are on a transformative journey to build a stronger, more unified team and the ability to better adapt to market needs," says Abhay Singhal, co-founder and chief executive officer of InMobi Advertising. "Centralising our advertising GTM across all product lines is essential for maintaining our growth momentum, and Kunal's proven expertise with the company across InMobi Exchange positions him as the perfect leader for this initiative.' Nagpal has played a pivotal role in the year-over-year growth of InMobi Exchange—developing it into the second largest full-funnel mobile sell-side platform in the industry—during the past five years, overseeing and guiding its expansion efforts beyond a mobile and in-app focus, a leading contender in the global advertising space. In his new role, Nagpal will spearhead the monetisation efforts for Glance, the company's commerce inspiration platform, and oversee the integration of InMobi Exchange, InMobi DSP, and the company's first-party advertising platform. This alignment of resources sets the stage for a comprehensive and integrated approach that aims to deliver immense value to marketers worldwide. 'The drive to redefine advertising through innovation requires strong leadership and bold strategies,' says Kunal Nagpal, chief business officer, InMobi's advertising businesses. 'I am eager to embrace this challenge and collaborate with our incredible teams to generate even more value for our partners and customers.' This organisational evolution highlights InMobi's belief in the power of synergised strategies and dedicated teams, mirroring a broader industry trend toward greater integration and cooperation within the advertising ecosystem, the company stated in a press release.