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'New highly-targeted drugs': beanies for brain cancer to fund big project
'New highly-targeted drugs': beanies for brain cancer to fund big project

The Advertiser

time3 days ago

  • Health
  • The Advertiser

'New highly-targeted drugs': beanies for brain cancer to fund big project

The $3.5 million raised through the NRL Beanies for Brain Cancer Round will be used to develop a "big, bold project". Former Newcastle Knights star Mark Hughes, a brain cancer survivor, said it was "time to fund big research projects that have the potential to make a real difference". The Beanie Round has been running for nine years. This year's event in June sold about 130,000 beanies. Mr Hughes considers every beanie to be a symbol of hope. He said the money raised would "give patients the chance to get involved in clinical trials". The Mark Hughes Foundation Centre for Brain Cancer Research will partner with industry and researchers in Queensland to develop "new highly-targeted drugs". The drugs will be "delivered directly to the site of the brain tumour via theranostics". This treatment, which can be used for a range of cancers, involves a PET scanner looking for specific targets on tumour cells. If the targets are present, a radioactive form of the drug is given as an injection. The drug targets the tumour cells while "avoiding healthy areas". Mark Hughes Foundation centre director Mike Fay said "we know radiation works for brain tumours, we just need to make it work better". "Patients want us to be brave and develop and trial new treatments," said Professor Fay, a radiation oncologist. He said the Newcastle-based research centre was "uniquely placed to do novel drug development" and trials in "a small number of patients". Effective drugs could be scaled up "in partnership with pharmaceutical companies". Professor Fay sees patients in the clinic every week who "want and deserve better treatments for brain cancer". If the project is successful, it could be rolled out quickly in clinics across the country. The Mark Hughes Foundation has been funding medical research into brain cancer for 11 years. It's the leading cause of cancer death in Australians under 40 and children under 10. In the Hunter, about 100 to 120 people are diagnosed with brain cancer a year. Across Australia, it's about 2000 people. Only two in 10 of these people will survive five years after diagnosis. Mr Hughes, a two-time premiership winner with the Knights, was diagnosed with brain cancer in 2013. He and wife Kirralee started the foundation in a bid to boost research efforts and survival rates. The couple is known for doing epic adventures in groups to raise money for the foundation. This has included the Kokoda Track, Mount Kilimanjaro, base camp at Mount Everest, Borneo and Tasmania. Last year, the foundation gave $1 million for a new project with Carrie Bickmore's brain cancer mission in Melbourne. At the time, Mr Hughes said a "one-team mentality" was crucial in the fight against brain cancer. His experience in sport inspired his approach to tackling brain cancer. "Playing team sport - you get injured, you get up, go to the physio and get yourself ready to go again next week," he said last year. "I think I've got a bit of that mentality in me. When I got injured, I would get it fixed and tackle life from there." The $3.5 million raised through the NRL Beanies for Brain Cancer Round will be used to develop a "big, bold project". Former Newcastle Knights star Mark Hughes, a brain cancer survivor, said it was "time to fund big research projects that have the potential to make a real difference". The Beanie Round has been running for nine years. This year's event in June sold about 130,000 beanies. Mr Hughes considers every beanie to be a symbol of hope. He said the money raised would "give patients the chance to get involved in clinical trials". The Mark Hughes Foundation Centre for Brain Cancer Research will partner with industry and researchers in Queensland to develop "new highly-targeted drugs". The drugs will be "delivered directly to the site of the brain tumour via theranostics". This treatment, which can be used for a range of cancers, involves a PET scanner looking for specific targets on tumour cells. If the targets are present, a radioactive form of the drug is given as an injection. The drug targets the tumour cells while "avoiding healthy areas". Mark Hughes Foundation centre director Mike Fay said "we know radiation works for brain tumours, we just need to make it work better". "Patients want us to be brave and develop and trial new treatments," said Professor Fay, a radiation oncologist. He said the Newcastle-based research centre was "uniquely placed to do novel drug development" and trials in "a small number of patients". Effective drugs could be scaled up "in partnership with pharmaceutical companies". Professor Fay sees patients in the clinic every week who "want and deserve better treatments for brain cancer". If the project is successful, it could be rolled out quickly in clinics across the country. The Mark Hughes Foundation has been funding medical research into brain cancer for 11 years. It's the leading cause of cancer death in Australians under 40 and children under 10. In the Hunter, about 100 to 120 people are diagnosed with brain cancer a year. Across Australia, it's about 2000 people. Only two in 10 of these people will survive five years after diagnosis. Mr Hughes, a two-time premiership winner with the Knights, was diagnosed with brain cancer in 2013. He and wife Kirralee started the foundation in a bid to boost research efforts and survival rates. The couple is known for doing epic adventures in groups to raise money for the foundation. This has included the Kokoda Track, Mount Kilimanjaro, base camp at Mount Everest, Borneo and Tasmania. Last year, the foundation gave $1 million for a new project with Carrie Bickmore's brain cancer mission in Melbourne. At the time, Mr Hughes said a "one-team mentality" was crucial in the fight against brain cancer. His experience in sport inspired his approach to tackling brain cancer. "Playing team sport - you get injured, you get up, go to the physio and get yourself ready to go again next week," he said last year. "I think I've got a bit of that mentality in me. When I got injured, I would get it fixed and tackle life from there." The $3.5 million raised through the NRL Beanies for Brain Cancer Round will be used to develop a "big, bold project". Former Newcastle Knights star Mark Hughes, a brain cancer survivor, said it was "time to fund big research projects that have the potential to make a real difference". The Beanie Round has been running for nine years. This year's event in June sold about 130,000 beanies. Mr Hughes considers every beanie to be a symbol of hope. He said the money raised would "give patients the chance to get involved in clinical trials". The Mark Hughes Foundation Centre for Brain Cancer Research will partner with industry and researchers in Queensland to develop "new highly-targeted drugs". The drugs will be "delivered directly to the site of the brain tumour via theranostics". This treatment, which can be used for a range of cancers, involves a PET scanner looking for specific targets on tumour cells. If the targets are present, a radioactive form of the drug is given as an injection. The drug targets the tumour cells while "avoiding healthy areas". Mark Hughes Foundation centre director Mike Fay said "we know radiation works for brain tumours, we just need to make it work better". "Patients want us to be brave and develop and trial new treatments," said Professor Fay, a radiation oncologist. He said the Newcastle-based research centre was "uniquely placed to do novel drug development" and trials in "a small number of patients". Effective drugs could be scaled up "in partnership with pharmaceutical companies". Professor Fay sees patients in the clinic every week who "want and deserve better treatments for brain cancer". If the project is successful, it could be rolled out quickly in clinics across the country. The Mark Hughes Foundation has been funding medical research into brain cancer for 11 years. It's the leading cause of cancer death in Australians under 40 and children under 10. In the Hunter, about 100 to 120 people are diagnosed with brain cancer a year. Across Australia, it's about 2000 people. Only two in 10 of these people will survive five years after diagnosis. Mr Hughes, a two-time premiership winner with the Knights, was diagnosed with brain cancer in 2013. He and wife Kirralee started the foundation in a bid to boost research efforts and survival rates. The couple is known for doing epic adventures in groups to raise money for the foundation. This has included the Kokoda Track, Mount Kilimanjaro, base camp at Mount Everest, Borneo and Tasmania. Last year, the foundation gave $1 million for a new project with Carrie Bickmore's brain cancer mission in Melbourne. At the time, Mr Hughes said a "one-team mentality" was crucial in the fight against brain cancer. His experience in sport inspired his approach to tackling brain cancer. "Playing team sport - you get injured, you get up, go to the physio and get yourself ready to go again next week," he said last year. "I think I've got a bit of that mentality in me. When I got injured, I would get it fixed and tackle life from there." The $3.5 million raised through the NRL Beanies for Brain Cancer Round will be used to develop a "big, bold project". Former Newcastle Knights star Mark Hughes, a brain cancer survivor, said it was "time to fund big research projects that have the potential to make a real difference". The Beanie Round has been running for nine years. This year's event in June sold about 130,000 beanies. Mr Hughes considers every beanie to be a symbol of hope. He said the money raised would "give patients the chance to get involved in clinical trials". The Mark Hughes Foundation Centre for Brain Cancer Research will partner with industry and researchers in Queensland to develop "new highly-targeted drugs". The drugs will be "delivered directly to the site of the brain tumour via theranostics". This treatment, which can be used for a range of cancers, involves a PET scanner looking for specific targets on tumour cells. If the targets are present, a radioactive form of the drug is given as an injection. The drug targets the tumour cells while "avoiding healthy areas". Mark Hughes Foundation centre director Mike Fay said "we know radiation works for brain tumours, we just need to make it work better". "Patients want us to be brave and develop and trial new treatments," said Professor Fay, a radiation oncologist. He said the Newcastle-based research centre was "uniquely placed to do novel drug development" and trials in "a small number of patients". Effective drugs could be scaled up "in partnership with pharmaceutical companies". Professor Fay sees patients in the clinic every week who "want and deserve better treatments for brain cancer". If the project is successful, it could be rolled out quickly in clinics across the country. The Mark Hughes Foundation has been funding medical research into brain cancer for 11 years. It's the leading cause of cancer death in Australians under 40 and children under 10. In the Hunter, about 100 to 120 people are diagnosed with brain cancer a year. Across Australia, it's about 2000 people. Only two in 10 of these people will survive five years after diagnosis. Mr Hughes, a two-time premiership winner with the Knights, was diagnosed with brain cancer in 2013. He and wife Kirralee started the foundation in a bid to boost research efforts and survival rates. The couple is known for doing epic adventures in groups to raise money for the foundation. This has included the Kokoda Track, Mount Kilimanjaro, base camp at Mount Everest, Borneo and Tasmania. Last year, the foundation gave $1 million for a new project with Carrie Bickmore's brain cancer mission in Melbourne. At the time, Mr Hughes said a "one-team mentality" was crucial in the fight against brain cancer. His experience in sport inspired his approach to tackling brain cancer. "Playing team sport - you get injured, you get up, go to the physio and get yourself ready to go again next week," he said last year. "I think I've got a bit of that mentality in me. When I got injured, I would get it fixed and tackle life from there."

Millions raised for Mark Hughes Foundation in Beanie for Brain Cancer round
Millions raised for Mark Hughes Foundation in Beanie for Brain Cancer round

The Advertiser

time30-06-2025

  • Health
  • The Advertiser

Millions raised for Mark Hughes Foundation in Beanie for Brain Cancer round

THE RUGBY league community banded together to raise a whopping $3.5 million in the Beanies for Brain Cancer round of the NRL. The initiative led by the Mark Hughes Foundation (MHF) saw a sea of purple and grey beanies on Friday, June 27, at McDonald Jones Stadium when the Knights took on the Raiders, and across all NRL matches for the weekend. This year's funds surpassed the $3.1 million raised in 2024, with over 130,000 beanies sold and Sportsbet donating $1000 for each of the 60 tries scored during Round 17. MHF founder Mark Highes said it never ceased to amaze him how much this round meant to the rugby league community. "The reality of living with brain cancer and the devastating effects that it has on so many Australians is something that would be easy to find overcoming, but this is never the case for the rugby league community," he said. "Every beanie is a symbol of hope, and we now have 3.5 million more reasons to tackle this insidious disease harder than before." NRL CEO Andrew Abdo said he was proud of how the community had stepped up in the fight against brain cancer. "This is a time when fans put aside their rivalries and come together in a wonderful show of support for a very worthy cause," he said. "Congratulations to the Mark Hughes Foundation for the work they have done in leading fundraising and research into fighting brain cancer." Also contributing to the fundraising was a 70-strong Big Three Trek contingent that tackled the 150km walk from Rugby League Central in Sydney to Newcastle to raise over $335,000 across three days. Novocastrian Scott Hingston successfully ran from AAMI Park in Melbourne to Newcastle, completing an epic 1100km journey, running 24 marathons in 12 days to raise awareness and $116,000 for brain cancer research. THE RUGBY league community banded together to raise a whopping $3.5 million in the Beanies for Brain Cancer round of the NRL. The initiative led by the Mark Hughes Foundation (MHF) saw a sea of purple and grey beanies on Friday, June 27, at McDonald Jones Stadium when the Knights took on the Raiders, and across all NRL matches for the weekend. This year's funds surpassed the $3.1 million raised in 2024, with over 130,000 beanies sold and Sportsbet donating $1000 for each of the 60 tries scored during Round 17. MHF founder Mark Highes said it never ceased to amaze him how much this round meant to the rugby league community. "The reality of living with brain cancer and the devastating effects that it has on so many Australians is something that would be easy to find overcoming, but this is never the case for the rugby league community," he said. "Every beanie is a symbol of hope, and we now have 3.5 million more reasons to tackle this insidious disease harder than before." NRL CEO Andrew Abdo said he was proud of how the community had stepped up in the fight against brain cancer. "This is a time when fans put aside their rivalries and come together in a wonderful show of support for a very worthy cause," he said. "Congratulations to the Mark Hughes Foundation for the work they have done in leading fundraising and research into fighting brain cancer." Also contributing to the fundraising was a 70-strong Big Three Trek contingent that tackled the 150km walk from Rugby League Central in Sydney to Newcastle to raise over $335,000 across three days. Novocastrian Scott Hingston successfully ran from AAMI Park in Melbourne to Newcastle, completing an epic 1100km journey, running 24 marathons in 12 days to raise awareness and $116,000 for brain cancer research. THE RUGBY league community banded together to raise a whopping $3.5 million in the Beanies for Brain Cancer round of the NRL. The initiative led by the Mark Hughes Foundation (MHF) saw a sea of purple and grey beanies on Friday, June 27, at McDonald Jones Stadium when the Knights took on the Raiders, and across all NRL matches for the weekend. This year's funds surpassed the $3.1 million raised in 2024, with over 130,000 beanies sold and Sportsbet donating $1000 for each of the 60 tries scored during Round 17. MHF founder Mark Highes said it never ceased to amaze him how much this round meant to the rugby league community. "The reality of living with brain cancer and the devastating effects that it has on so many Australians is something that would be easy to find overcoming, but this is never the case for the rugby league community," he said. "Every beanie is a symbol of hope, and we now have 3.5 million more reasons to tackle this insidious disease harder than before." NRL CEO Andrew Abdo said he was proud of how the community had stepped up in the fight against brain cancer. "This is a time when fans put aside their rivalries and come together in a wonderful show of support for a very worthy cause," he said. "Congratulations to the Mark Hughes Foundation for the work they have done in leading fundraising and research into fighting brain cancer." Also contributing to the fundraising was a 70-strong Big Three Trek contingent that tackled the 150km walk from Rugby League Central in Sydney to Newcastle to raise over $335,000 across three days. Novocastrian Scott Hingston successfully ran from AAMI Park in Melbourne to Newcastle, completing an epic 1100km journey, running 24 marathons in 12 days to raise awareness and $116,000 for brain cancer research. THE RUGBY league community banded together to raise a whopping $3.5 million in the Beanies for Brain Cancer round of the NRL. The initiative led by the Mark Hughes Foundation (MHF) saw a sea of purple and grey beanies on Friday, June 27, at McDonald Jones Stadium when the Knights took on the Raiders, and across all NRL matches for the weekend. This year's funds surpassed the $3.1 million raised in 2024, with over 130,000 beanies sold and Sportsbet donating $1000 for each of the 60 tries scored during Round 17. MHF founder Mark Highes said it never ceased to amaze him how much this round meant to the rugby league community. "The reality of living with brain cancer and the devastating effects that it has on so many Australians is something that would be easy to find overcoming, but this is never the case for the rugby league community," he said. "Every beanie is a symbol of hope, and we now have 3.5 million more reasons to tackle this insidious disease harder than before." NRL CEO Andrew Abdo said he was proud of how the community had stepped up in the fight against brain cancer. "This is a time when fans put aside their rivalries and come together in a wonderful show of support for a very worthy cause," he said. "Congratulations to the Mark Hughes Foundation for the work they have done in leading fundraising and research into fighting brain cancer." Also contributing to the fundraising was a 70-strong Big Three Trek contingent that tackled the 150km walk from Rugby League Central in Sydney to Newcastle to raise over $335,000 across three days. Novocastrian Scott Hingston successfully ran from AAMI Park in Melbourne to Newcastle, completing an epic 1100km journey, running 24 marathons in 12 days to raise awareness and $116,000 for brain cancer research.

'Special': 475 stadium staff to don beanies for annual NRL round
'Special': 475 stadium staff to don beanies for annual NRL round

The Advertiser

time23-06-2025

  • Sport
  • The Advertiser

'Special': 475 stadium staff to don beanies for annual NRL round

McDonald Jones Stadium will be a sea of purple and grey on Friday for the annual Beanie for Brain Cancer NRL round. All 475 stadium staff, including security guards, ticket attendants and food and beverage workers, will don a beanie when the Knights take on the Raiders at home. The bulk purchase equates to more than $10,000 raised for the Mark Hughes Foundation. It's the first time stadium owner Venues NSW has bought beanies for all staff, having supported the fundraiser in other ways in previous years. "When it all started to really kick off, we used to put the beanie sign out on the front of the venue and rename the stadium for beanie round," Mr Mantle said. "That was obviously great for building awareness when it was required, but as the foundation has grown, it's now naturally recognised, so it probably hasn't got the cut through that it used to have. "We looked at an opportunity to see how we could better reinvest that funding. "The best way we thought we could do that was to invest in the beanies, so we've purchased a beanie for every single event staff." Mark Hughes said he was very grateful for the support. "To see every staff member wearing our beanies here next Friday night will just make it that much more special," he said. The event will also be boosted by the arrival of participants on the annual Big Three trek, who walk from Sydney to McDonald Jones Stadium over three days, as well as Scott Hingston, who is running 1100km from Melbourne to Newcastle. Both initiatives have each raised more than $50,000 for the Mark Hughes Foundation. Hughes said the beanies fundraiser had gone from strength to strength each year. "We've come a long way," he said. "We've learned so much, and without the support of the good people who buy our beanies and support us in different ways, it doesn't happen." "I just see the beanies everywhere. People walk on the beach, walk on the streets. It's really overwhelming to see the support out there. "It's all about giving hope to brain cancer. So, people wearing their old beanies, people buying new beanies, it really is special." Mr Mantle is expecting a solid crowd for the much-loved NRL round. "Fortunately for us at the moment, the Knights are very well supported," he said. "We're on an average of just below 20,000 per game. So I'd expect well above 20,000. "I hope everybody comes in with the beanie on or if they don't have already have one, they purchase one on the night. I think it'll be amazing. "It's incredible to see how big this has gotten, and no doubt it could get so much bigger thanks to the work that Mark and Kirralee do with the foundation." McDonald Jones Stadium will be a sea of purple and grey on Friday for the annual Beanie for Brain Cancer NRL round. All 475 stadium staff, including security guards, ticket attendants and food and beverage workers, will don a beanie when the Knights take on the Raiders at home. The bulk purchase equates to more than $10,000 raised for the Mark Hughes Foundation. It's the first time stadium owner Venues NSW has bought beanies for all staff, having supported the fundraiser in other ways in previous years. "When it all started to really kick off, we used to put the beanie sign out on the front of the venue and rename the stadium for beanie round," Mr Mantle said. "That was obviously great for building awareness when it was required, but as the foundation has grown, it's now naturally recognised, so it probably hasn't got the cut through that it used to have. "We looked at an opportunity to see how we could better reinvest that funding. "The best way we thought we could do that was to invest in the beanies, so we've purchased a beanie for every single event staff." Mark Hughes said he was very grateful for the support. "To see every staff member wearing our beanies here next Friday night will just make it that much more special," he said. The event will also be boosted by the arrival of participants on the annual Big Three trek, who walk from Sydney to McDonald Jones Stadium over three days, as well as Scott Hingston, who is running 1100km from Melbourne to Newcastle. Both initiatives have each raised more than $50,000 for the Mark Hughes Foundation. Hughes said the beanies fundraiser had gone from strength to strength each year. "We've come a long way," he said. "We've learned so much, and without the support of the good people who buy our beanies and support us in different ways, it doesn't happen." "I just see the beanies everywhere. People walk on the beach, walk on the streets. It's really overwhelming to see the support out there. "It's all about giving hope to brain cancer. So, people wearing their old beanies, people buying new beanies, it really is special." Mr Mantle is expecting a solid crowd for the much-loved NRL round. "Fortunately for us at the moment, the Knights are very well supported," he said. "We're on an average of just below 20,000 per game. So I'd expect well above 20,000. "I hope everybody comes in with the beanie on or if they don't have already have one, they purchase one on the night. I think it'll be amazing. "It's incredible to see how big this has gotten, and no doubt it could get so much bigger thanks to the work that Mark and Kirralee do with the foundation." McDonald Jones Stadium will be a sea of purple and grey on Friday for the annual Beanie for Brain Cancer NRL round. All 475 stadium staff, including security guards, ticket attendants and food and beverage workers, will don a beanie when the Knights take on the Raiders at home. The bulk purchase equates to more than $10,000 raised for the Mark Hughes Foundation. It's the first time stadium owner Venues NSW has bought beanies for all staff, having supported the fundraiser in other ways in previous years. "When it all started to really kick off, we used to put the beanie sign out on the front of the venue and rename the stadium for beanie round," Mr Mantle said. "That was obviously great for building awareness when it was required, but as the foundation has grown, it's now naturally recognised, so it probably hasn't got the cut through that it used to have. "We looked at an opportunity to see how we could better reinvest that funding. "The best way we thought we could do that was to invest in the beanies, so we've purchased a beanie for every single event staff." Mark Hughes said he was very grateful for the support. "To see every staff member wearing our beanies here next Friday night will just make it that much more special," he said. The event will also be boosted by the arrival of participants on the annual Big Three trek, who walk from Sydney to McDonald Jones Stadium over three days, as well as Scott Hingston, who is running 1100km from Melbourne to Newcastle. Both initiatives have each raised more than $50,000 for the Mark Hughes Foundation. Hughes said the beanies fundraiser had gone from strength to strength each year. "We've come a long way," he said. "We've learned so much, and without the support of the good people who buy our beanies and support us in different ways, it doesn't happen." "I just see the beanies everywhere. People walk on the beach, walk on the streets. It's really overwhelming to see the support out there. "It's all about giving hope to brain cancer. So, people wearing their old beanies, people buying new beanies, it really is special." Mr Mantle is expecting a solid crowd for the much-loved NRL round. "Fortunately for us at the moment, the Knights are very well supported," he said. "We're on an average of just below 20,000 per game. So I'd expect well above 20,000. "I hope everybody comes in with the beanie on or if they don't have already have one, they purchase one on the night. I think it'll be amazing. "It's incredible to see how big this has gotten, and no doubt it could get so much bigger thanks to the work that Mark and Kirralee do with the foundation." McDonald Jones Stadium will be a sea of purple and grey on Friday for the annual Beanie for Brain Cancer NRL round. All 475 stadium staff, including security guards, ticket attendants and food and beverage workers, will don a beanie when the Knights take on the Raiders at home. The bulk purchase equates to more than $10,000 raised for the Mark Hughes Foundation. It's the first time stadium owner Venues NSW has bought beanies for all staff, having supported the fundraiser in other ways in previous years. "When it all started to really kick off, we used to put the beanie sign out on the front of the venue and rename the stadium for beanie round," Mr Mantle said. "That was obviously great for building awareness when it was required, but as the foundation has grown, it's now naturally recognised, so it probably hasn't got the cut through that it used to have. "We looked at an opportunity to see how we could better reinvest that funding. "The best way we thought we could do that was to invest in the beanies, so we've purchased a beanie for every single event staff." Mark Hughes said he was very grateful for the support. "To see every staff member wearing our beanies here next Friday night will just make it that much more special," he said. The event will also be boosted by the arrival of participants on the annual Big Three trek, who walk from Sydney to McDonald Jones Stadium over three days, as well as Scott Hingston, who is running 1100km from Melbourne to Newcastle. Both initiatives have each raised more than $50,000 for the Mark Hughes Foundation. Hughes said the beanies fundraiser had gone from strength to strength each year. "We've come a long way," he said. "We've learned so much, and without the support of the good people who buy our beanies and support us in different ways, it doesn't happen." "I just see the beanies everywhere. People walk on the beach, walk on the streets. It's really overwhelming to see the support out there. "It's all about giving hope to brain cancer. So, people wearing their old beanies, people buying new beanies, it really is special." Mr Mantle is expecting a solid crowd for the much-loved NRL round. "Fortunately for us at the moment, the Knights are very well supported," he said. "We're on an average of just below 20,000 per game. So I'd expect well above 20,000. "I hope everybody comes in with the beanie on or if they don't have already have one, they purchase one on the night. I think it'll be amazing. "It's incredible to see how big this has gotten, and no doubt it could get so much bigger thanks to the work that Mark and Kirralee do with the foundation."

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