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Does Age Affect Care Outcomes in Patients With COPD on NIV?
Does Age Affect Care Outcomes in Patients With COPD on NIV?

Medscape

time11 hours ago

  • Health
  • Medscape

Does Age Affect Care Outcomes in Patients With COPD on NIV?

TOPLINE: Health-related quality of life (HRQOL) did not differ significantly between younger and older patients with chronic obstructive pulmonary disease (COPD) suffering from chronic hypercapnic respiratory failure receiving long-term noninvasive ventilation (NIV), despite a higher comorbidity burden in older patients. METHODOLOGY: Researchers conducted a prospective, observational study to investigate the differences in HRQOL between younger and older patients with COPD and chronic hypercapnic respiratory failure receiving long-term NIV. They enrolled 237 patients between June 2015 and October 2021, with 41.8% enrolled as inpatients and 58.2% as outpatients, categorized into two age groups: younger (< 65 years) and older (≥ 65 years). HRQOL was assessed using the severe respiratory insufficiency (SRI) questionnaire, and factors affecting HRQOL — including anemia, autonomy impairment, exacerbation history, and comorbidities — were evaluated. A five-tier scale categorized autonomy impairments by severity with level 1 denoting minor impairments and level 5 indicating the most severe loss of independence or ability, which pose substantial challenges for nursing care. TAKEAWAY: No significant differences were found in SRI summary scores between age groups, despite older patients having a significantly higher burden of comorbidities (P = .014). Exacerbation frequency had a significant negative impact on SRI scores in both younger and older patients. Anemia was linked to a significant reduction in SRI scores only in younger patients, in whom it was more prevalent (29.1% vs 17.5%; P = .045). Any level of autonomy impairment negatively affected HRQOL in younger patients, whereas only higher levels (level of care ≥ 2) affected HRQOL in older patients. IN PRACTICE: 'Understanding of COPD with comprehensive care plans that address both medical and functional aspects, patient outcomes, and HRQOL might be improved,' the authors wrote. SOURCE: This study was led by Maximilian Zimmermann, Department of Pneumology, Witten/Herdecke University, Cologne, Germany. It was published online on June 7, 2025, in BMC Pulmonary Medicine. LIMITATIONS: The heterogeneity of the study cohort, due to inclusion of both inpatients and outpatients, may have led to variability in clinical status and care settings. Additionally, patients were eligible after 1 month of NIV, most had been on long-term therapy prior to inclusion, which could have influenced the assessment of HRQOL. Because the study was conducted at a single center, the results may not be applied to broader populations. DISCLOSURES: This study did not receive any research funding. The authors reported having no relevant conflicts of interest. This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

Chitkara University's innovation incubator backs 101 startups in 10 years
Chitkara University's innovation incubator backs 101 startups in 10 years

Hindustan Times

time2 days ago

  • Business
  • Hindustan Times

Chitkara University's innovation incubator backs 101 startups in 10 years

Chitkara University's incubation arm, the Chitkara Innovation Incubator Foundation (CIIF), has announced that it has funded 101 startups since its launch in 2015. Startups that have benefitted from CIIF's support include Studycaller, an edtech company that raised ₹ 1 crore from investor Mahavir Pratap Sharma. (HT File) The milestone marks CIIF's growing contribution to India's startup ecosystem through financial support and a structured incubation framework. CIIF offers more than funding—it provides early-stage ventures with mentoring, accelerator programmes, capacity-building support and investor connections. Over the years, it has engaged with over 5,000 startups, evaluated over 500 applications annually and mentored more than 200 ventures. The foundation also maintains a strong network of over 100 industry mentors and investors. Supported by national and state-level institutions including the department of science technology (DST), MeitY Startup Hub, Startup India and Startup Punjab, CIIF backs ventures across sectors such as fintech, healthtech, agritech, cleantech, edtech and deeptech. The focus remains on enabling startups to grow sustainably and address real-world challenges. Madhu Chitkara, pro-chancellor of the varsity, said reaching the 101-startup mark reflects the institution's commitment to building ventures that create real-world impact. 'We will continue to foster innovation, nurture entrepreneurial talent, and help build businesses that drive meaningful change for India and beyond,' she added. Startups that have benefitted from CIIF's support include Studycaller, an edtech company that raised ₹1 crore from investor Mahavir Pratap Sharma. The platform received strategic guidance and investor connections through the incubator. In the deeptech sector, Aumsat has used satellite and AI technologies to address over 2,600 pipeline leaks and map 1.5 lakh kilometers of infrastructure, with support from CIIF including ₹50 lakh in funding. Another startup, Adiabatic, has developed high-performance lithium-ion battery packs and established a manufacturing facility with CIIF's assistance from prototype to production. In healthtech, Svastek's patented respiratory NIV mask attracted ₹2 crore in funding from IAN Angel Fund and was featured on Shark Tank India. CIIF supported the venture in product development and funding facilitation.

3 acute flaccid paralysis cases reported in Sambhajinagar
3 acute flaccid paralysis cases reported in Sambhajinagar

Time of India

time3 days ago

  • Health
  • Time of India

3 acute flaccid paralysis cases reported in Sambhajinagar

Chhatrapati Sambhajinagar: Health authorities in Phulambri taluka have diagnosed three children from a local hamlet with Acute Flaccid Paralysis (AFP). The children — aged two-and-a-half, nine and 11 years old, rapidly developed weakness and reduced muscle strength. After initial treatment at a local hospital, the children were transferred to a private hospital in Chhatrapati Sambhajinagar on Saturday. District health officer Dr. Abhay Dhanorkar said while all three are confirmed cases of AFP, the underlying cause could be polio, Guillain-Barré Syndrome (GBS), or another post-viral infection. "An 11-year-old boy has already tested negative for GBS and is recovering," he said. "The lab results for the other two children are still pending. As part of a thorough investigation, stool samples from all three children have been sent to the National Institute of Virology (NIV) in Pune for further analysis," he added. Health authorities have also been collecting samples of drinking water in the village Mauje Khambatvasti for lab testing. "We have collected water samples from the homes of the three children and neighbouring houses. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Many Are Watching Tariffs - Few Are Watching What Nvidia Just Launched Seeking Alpha Read More Undo Also, mass screening of villagers is being carried out," Dhanorkar said. "The hamlet has a population of around 400, and nobody has reported major health complaints so far,"he added. According to the health authorities, the nine-year-old boy first developed weakness and reduced muscle strength on July 12, following which his family consulted with the local doctors. Later, another 11-year-old boy complained of similar health issues on July 16, and another 2.5-year-old suffered similar conditions the following day.

One more suspected Nipah case reported in Palakkad
One more suspected Nipah case reported in Palakkad

The Hindu

time16-07-2025

  • Health
  • The Hindu

One more suspected Nipah case reported in Palakkad

One more suspected Nipah case was reported in the district on Wednesday, prompting health officials to take swift action to prevent the spread of the virus. The State has seen a recent surge in Nipah cases with four infections being reported in less than three weeks from adjoining districts of Palakkad and Malappuram. In the latest case, the son of a 58-year-old man from Kumaramputhur who succumbed to the deadly virus at Moulana Hospital, Perinthalmanna, on Saturday last, was found Nipah positive in the initial test done at Government Medical College Hospital laboratory at Manjeri. Health Minister Veena George said that further tests would be conducted for final confirmation. However, health officials on Wednesday began tracing the people who had contacted the infected person in the last couple of weeks. She said a route map of the infected person was prepared and counter measures were in full swing the prevent the spread of the virus. 'He was on the contact list of the person who died of Nipah and was in isolation. His family tree was also prepared. We will ensure that his family gets utmost psychological support and care,' said Ms. George. The Minister said that 723 people across the State were under observation for Nipah. As many as 51 were identified as contacts of the latest person who tested positive during the initial investigation. While 212 people are in quarantine in Malappuram district, 394 people in Palakkad are under observation, said Ms. George. In Kozhikode, 114 people are in isolation when Ernakulam district has two and Thrissur one in isolation. The Minister said that 10 persons in isolation are under treatment in Malappuram and seven in Palakkad. She said 84 samples tested negative in Malappuram so far. Palakkad district has so far reported three Nipah cases including the suspected one. When one affected person succumbed to the virus, two are currently under treatment. Health workers visited 1,568 houses in Nipah reported area at Kumaramputhur on Wednesday and completed their fever survey. The number calls reaching the Nipah control cell saw an increase on Wednesday. Officials said they got 42 calls, the largest on a single day. The samples of 150 bats collected by a team of scientists from the National Institute of Virology (NIV), Pune, were sent for testing. The district animal husbandry officials too collected animal samples from within a kilometre radius of the Nipah infected person. District Supply Officer said here on Wednesday that direct ration supply was ensured for 872 families within the containment zone. District Collector G. Priyanka warned people in containment zones against crowding and moving out without masks. The Nipah control room can be reached round the clock at 0491 2504002. For counselling, people can reach out to 75109 05080.

Kerala: 32-year-old man tests positive for Nipah
Kerala: 32-year-old man tests positive for Nipah

Hans India

time16-07-2025

  • Health
  • Hans India

Kerala: 32-year-old man tests positive for Nipah

Palakkad: A 32-year-old man on Wednesday tested positive for Nipah and is currently under treatment at the Palakkad Medical College hospital. Notably, his father recently passed away and was Nipah positive. The test results came out on Wednesday. The test was done at a centre in Malappuram district. Generally, all samples are first tested and then sent to the National Institute of Virology (NIV) and the authorities are now waiting for that result too. This is the third case being registered in Palakkad. A woman from there is being treated at the Kozhikode Medical College hospital. Currently, there are 374 people in the district who are under constant medical observation. The authorities have now identified three village councils in the districts and four wards in Mannarakad area which have been converted into high risk areas and some areas have been converted into containment zones. The local health and police officials are on high alert and are leaving nothing to chance as multiple teams of health workers are conducting door-to-door visits to monitor symptoms and educate residents on preventive measures. The use of face masks has been made mandatory for patients, caregivers, and healthcare personnel. As a precautionary measure, at present Malappuram, Kozhikode, Ernakulam, Thrissur, Kannur, and Wayanad districts are on alert. Earlier on Wednesday, a tense moment was witnessed when a local resident lost his cool after he was stopped by two police officials who were on duty in a containment area. Angered by the way the police personnel behaved with him, a brawl broke out between them and, after intervention by others, peace finally prevailed. Health authorities continue to stress the need for vigilance, early detection, and adherence to safety protocols to prevent further transmission of the zoonotic virus, believed to be spread by fruit bats.

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