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Health Line
6 days ago
- Health
- Health Line
GLP-1 Drugs May Cause Dehydration, Experts Say, Especially In Extreme Heat
Experts say people who take GLP-1 weight loss medications should stay hydrated, particularly when temperatures are high. The mechanisms of GLP-1 drugs that help reduce appetite, as well as their side effects, may lead to dehydration. Dehydration can cause symptoms such as dizziness and a dry throat, as well as potentially lead to cramps and even seizures. Dehydration could be a potential side effect of taking GLP-1 medications like Ozempic and Mounjaro. Experts say dehydration can easily occur as people lose weight with GLP-1 drugs, as their hunger and thirst impulses are tamped down by these medications. 'Dehydration is a serious risk when taking GLP-1 medications,' Kais Rona, MD, a bariatric surgeon of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California, told Healthline. 'A reduction in hunger drive may be associated with a reduction in thirst drive as well. Patients can develop dehydration rather quickly while taking these medications.' Rona and other experts emphasize that dehydration is not a direct result of taking the GLP-1 drugs. Rather, dehydration develops because of the medication's mechanisms to lower the body's desire for food and consequently liquids. Here's what you need to know about staying hydrated while taking GLP-1 drugs, particularly during rising temperatures. GLP-1 side effects may cause dehydration Common side effects from GLP-1 drugs, such as nausea, vomiting, and diarrhea, can exacerbate dehydration. 'These medications work by reducing appetite and slowing down gut function, which not only result in a reduction in food intake, but a reduction in fluid intake as well,' Rona explained. 'Furthermore, the most common side effects associated with GLP-1 medications are gastrointestinal symptoms such as nausea, constipation, and vomiting.' These symptoms, he added, may exacerbate dehydration. 'GLP-1 drugs slow gastric emptying, leading to early satiety, and making you less likely to drink adequate fluids regularly,' said Michael Snyder, MD, a bariatric surgeon and an obesity specialist at FuturHealth. 'They can also increase the risk of nausea, vomiting, diarrhea, constipation, and other GI side effects — all of which can be made worse by dehydration.' Jessica Crandall Snyder, a registered dietitian and a medical advisor to FuturHealth, noted the issue is even more important in warmer weather. 'GLP-1s can interfere with your body's natural hunger and thirst cues, meaning you might not feel thirsty even when your body needs fluids,' she told Healthline. 'They may also impact thermoregulation, making it harder for the body to cool itself effectively. In hot weather, that could increase the risk of overheating or even heat-related illness.' Zhaoping Li, MD, a professor of clinical medicine and the chief of the Division of Clinical Nutrition at the University of California Los Angeles, said GLP-1 drugs can also cause people to urinate more often. That can also lead to dehydration. 'You need to be careful,' Li told Healthline. Health dangers from dehydration Dehydration occurs when the body doesn't adequately replace the fluids it loses when sweating and urinating. You can also become low on fluids if you have an illness, especially one that causes fever. People who are more likely to become dehydrated include: athletes older adults people working in hot weather infants and young children people with chronic conditions people who live at high altitudes The symptoms of dehydration include: increased thirst dry mouth fatigue dizziness dry skin headache In more serious cases, dehydration can cause a rapid heart beat and rapid breathing. Li said a person who is dehydrated may also develop low blood pressure. 'In addition, as you urinate, you can lose calcium, potassium, and salt,' she said. Dehydration can lead to cramps and even seizures, especially if there is electrolyte imbalance. Rona said there are a variety of serious ailments that can also be produced by dehydration. 'Dehydration can result in significant electrolyte abnormalities, which may present as vague symptoms such as confusion, decrease in energy levels, fatigue, or muscle spasms,' he said. 'Inadequate hydration can also worsen constipation, which is a common side effect of the medication. Lastly, severe dehydration can lead to blood pressure abnormalities as well as kidney injury, which can sometimes result in permanent kidney damage if not addressed urgently.' Tips to stay hydrated On their website, officials at Reviv Lounge, a weight loss treatment center in Wisconsin, discuss the importance of hydration while taking GLP-1 medications. 'Water is essential for nearly every function in your body, but it plays a particularly crucial role when you're actively trying to lose weight,' they say. They also note that when the body is low on fluids, it can hold onto excessive sodium, which can cause bloating and water retention. Staying hydrated is key to maintaining overall health. A 2023 study concluded that hydration can also help with healthy aging. In general, it's recommended that males drink 13 cups of water per day and women drink nine cups of water per day. Experts interviewed by Healthline agreed it's important to stay hydrated while taking weight loss medications. 'It is very important to prioritize hydration when taking a GLP-1 medication,' said Rona. 'Water with or without natural flavors and electrolyte-based fluids are the preferred sources of hydration. It is important to reduce the intake of sugary beverages as well as carbonated beverages, which can sometimes exacerbate the gastrointestinal side effects of the medication,' he added. 'It is critical to know your hydration needs and keep track of your intake,' Michael Snyder noted. 'This is the same as we recommend for anyone following a dietary regimen, but more so if you are on GLP-1 medications, since they can notably affect hydration status.' Jessica Crandell Snyder shared some practical advice for people taking GLP-1 medications. 'Start with a comprehensive plan, not just the medication. Stay hydrated and drink electrolyte-rich fluids if you're experiencing GI symptoms,' she said. 'If you are nauseated, take small, frequent sips of cold beverages. Continue to prioritize high protein meals and stay in close communication with your healthcare provider, especially in the early weeks or if digestive symptoms persist. GLP-1s are powerful tools, but they're most effective when supported by lifestyle shifts,' she recommended. What to know about GLP-1 medications GLP-1 medications fall into two categories. Ozempic, Rybelsus, and Wegovy contain the active ingredient semaglutide. Ozempic and Rybelsus are used for type 2 diabetes. While Ozempic is often prescribed off-label for weight loss, Wegovy is approved by the FDA for weight loss. Mounjaro and Zepbound contain the active ingredient tirzepatide. Mounjaro has been approved to treat type 2 diabetes, while Zepbound has been approved by the Food and Drug Administration (FDA) for weight loss. In the past three years, numerous studies have lauded the weight loss benefits of GLP-1 drugs. In addition, researchers have reported that GLP-1 drugs can help: reduce the risk of some cancers reduce the risk of a heart attack curb addictive behaviors such as smoking and alcoholism reduce rheumatoid arthritis flare-ups However, these GLP-1 drugs can produce side effects. Among them: nausea and vomiting diarrhea constipation abdominal pain indigestion Li said it's important to drink plenty of fluids and consume enough protein when taking GLP-1 drugs. In fact, a recent study reported that protein can help prevent muscle loss caused by GLP-1 drugs. 'They are plenty of reasons for people to take weight loss medications, but you need to be careful,' Li said.
STV News
16-07-2025
- Health
- STV News
'People think my wife is drunk but she's living with a rare brain disease'
Glenn Stewart is a full-time carer to his wife Rona, who lives with progressive supranuclear palsy The little-known neurological condition is often mistaken for drunkenness as it causes people to lose their balance Scientists in Edinburgh say a recent study could mark a step forward in slowing the disease's progression They have examined how a crucial protein, called tau, spreads in the brain Glenn and Rona say more awareness of the condition is needed in Scotland An Edinburgh couple have welcomed new research into a rare and little-known neurological condition that is often mistaken for drunkenness. Glenn Stewart is a full-time carer to his wife Rona, who lives with progressive supranuclear palsy, or PSP. Researchers say the condition is like a mixture of motor neurone disease and Alzheimer's, affecting around one in every 18,000 people. It cannot be cured but scientists at the University of Edinburgh believe they may be on the cusp of a breakthrough. Glenn and Rona have been together for over 50 years. They were high school sweethearts who built a life in Edinburgh. STV News Glenn and Rona Stewart have been together since high school. But when Rona began to fall regularly, it soon became clear something was seriously wrong. 'My balance is terrible,' Rona told STV News. 'I can't get up from the chair anymore. Glenn does everything. I sit and do nothing. It's horrendous, it's very frustrating.' Now Glenn is her full-time carer, helping Rona to the bathroom every half an hour. They face the same quiet battle daily – not just with the disease, but with how people perceive it. 'When she would fall in public, people just assumed she was drunk,' said Glenn. 'One time she fell backwards on the steps and broke her vertebrae. I wasn't there to catch her. 'It's one of those situations where people don't step in to help because they think it's something else. We need more awareness in Scotland. Most of the research is happening down south.' Supplied Glenn Stewart and his wife Rona. PSP is a degenerative brain condition that affects movement, balance, vision and speech. Researchers describe it as a cross between motor neurone disease and Alzheimer's. There is no cure but scientists at the University of Edinburgh say a recent study could mark a step forward in slowing the disease's progression. STV News Scientists in Edinburgh believe they may be on the cusp of a breakthrough. Thanks to brain tissue donations, researchers are now able to examine how a crucial protein, called tau, spreads in the brain. Its buildup is known to contribute to both PSP and Alzheimer's. Scientists examined synapses in donated post-mortem brain tissue samples from people who died with PSP. They found evidence of tau inside synaptic connections and its presence was linked to synapse death, suggesting the toxic protein was killing these connections. Tara Spires-Jones, professor of neurodegeneration and director of the Centre for Discovery Brain Sciences at the University of Edinburgh, said: 'We want to understand why synapses are dying and how tau moves from one part of the brain to another. 'Wherever tau goes, brain cells die. Age is the biggest risk factor and science is the only way to fight back.' The team hope their work could eventually lead to a treatment that slows PSP's march, giving patients more time and independence. It's a discovery that's come too late for Rona, but she and Glenn are determined to make the most of every moment together. 'We've been together for 56 years,' said Glenn. 'We love one another. That's what keeps us going.' Get all the latest news from around the country Follow STV News Scan the QR code on your mobile device for all the latest news from around the country
Time of India
12-07-2025
- Entertainment
- Time of India
ILY:1 Rona opens up about saesang fans; shares ordeal about getting stalked
Rona of the K-pop group ILY:1 made headlines after revealing how saesang fans have been stalking her and coming to her house. The idol shared a plea to the public to help her in the matter. Rona shared her experience with a saesang fan who has been bothering her and the group for quite some time. On July 8, the member took to a popular fan forum application to share her ordeal with fans. The idol shared that currently she has been undergoing a lot of stress lately due to a fan who has been stalking her and even obtained access to her phone number, address, and even came to visit her at her house. Rona also added that this individual has been leaking her information to other people as well and has been breaching her privacy and security. Her statement on the fan forum read, 'I've always thought of Only:1 as truly close friends and family, so I shared my daily life with you all. I talked about good things, fun things, what I did today — everything'. 'But I didn't know that doing that would lead to my personal information leaking. People now know my phone number, where I live, our schedule… they even came to see me and found out personal details about me, and now they're telling others…I'm really scared and don't know what to do…I know I should always try to be careful with everything I say and do, so I'm really sorry that it ended up like this…' she continued. She also requested that this kind of behaviour come to an end, as she and all of the members have been worried about their safety. She also issued an apology and shared, 'It's true that I should've been more careful, but I really hope this doesn't happen again. I wish it would stop. Even if you did it out of affection, this isn't right…I really love Korea, and I wanted to be here for a long time, but now Korea feels so scary. My hands are still shaking from fear… Because of this, I'm scared of growing distant from Only:1, too'. Fans have been showing concern over the matter, and have also been urging the idol's management agency to take strict action against the saesang fans and anyone who has leaked her information as well.
Toronto Sun
13-06-2025
- Lifestyle
- Toronto Sun
Colin and Justin: Live large, pay less
Wallpapering, reupholstering an existing sofa and chairs, repainting the fireplace and coffee table, and installing $20 drapery panels from a hotel surplus store, revived this formerly drab lounge. Reviews and recommendations are unbiased and products are independently selected. Postmedia may earn an affiliate commission from purchases made through links on this page. Ten ways to add style without breaking the bank This advertisement has not loaded yet, but your article continues below. THIS CONTENT IS RESERVED FOR SUBSCRIBERS ONLY Subscribe now to read the latest news in your city and across Canada. Unlimited online access to articles from across Canada with one account. Get exclusive access to the Toronto Sun ePaper, an electronic replica of the print edition that you can share, download and comment on. Enjoy insights and behind-the-scenes analysis from our award-winning journalists. Support local journalists and the next generation of journalists. Daily puzzles including the New York Times Crossword. SUBSCRIBE TO UNLOCK MORE ARTICLES Subscribe now to read the latest news in your city and across Canada. Unlimited online access to articles from across Canada with one account. Get exclusive access to the Toronto Sun ePaper, an electronic replica of the print edition that you can share, download and comment on. Enjoy insights and behind-the-scenes analysis from our award-winning journalists. Support local journalists and the next generation of journalists. Daily puzzles including the New York Times Crossword. REGISTER / SIGN IN TO UNLOCK MORE ARTICLES Create an account or sign in to continue with your reading experience. Access articles from across Canada with one account. Share your thoughts and join the conversation in the comments. Enjoy additional articles per month. Get email updates from your favourite authors. THIS ARTICLE IS FREE TO READ REGISTER TO UNLOCK. Create an account or sign in to continue with your reading experience. Access articles from across Canada with one account Share your thoughts and join the conversation in the comments Enjoy additional articles per month Get email updates from your favourite authors Don't have an account? Create Account Now, perhaps than previously, the credit crunch is pressing ever harder. Priorities are undoubtedly changing, and, accordingly, consumers are appraising ways in which to moderate spend, without compromising style. To this end, we've assembled a precis of simple things to keep your home space abreast of style, without breaking the bank. 1. First up, you don't need a degree in interior design to operate a paintbrush: you might be surprised by just how much a lick of paint can muster an entirely new aesthetic. DIY stores such as Rona and Home Hardware merchant own brand quality paint at affordable price points, so head on in, grab a few tester pots and plan a brighter future. Alternatively, be inspired by pricier Farrow and Ball product and have paint mixed to match, using in the in store system at Home Depot. Your noon-hour look at what's happening in Toronto and beyond. By signing up you consent to receive the above newsletter from Postmedia Network Inc. Please try again This advertisement has not loaded yet, but your article continues below. 2. Switching up orientation, moving furniture around your room, or transitioning pieces from one zone to another are all easy way to change the feel of what you already have, with a zero spend. Shops do it all the time to make you think their stock is regularly changing: they call it 'rotation' or 'merchandising'. We call it common sense and making the best of what you already have. 3. Purge the clutter to amplify valuable space. Do a charity shop run and help others as you help yourself. Mindful that cleaning costs nothing, let light flood in by running a cloth around windows, kitchens and bathrooms. And don't forget matters olfactory; make sure your space smells good to help freshen the overall feel. Elbows up – find some of Canada's best home scenting products at The brand's entire range is available for shipping cross Canada. This advertisement has not loaded yet, but your article continues below. 4. 'Reversion' (re use, repaint, reupholster etc) to bring new life to redundant possessions. Pop new pictures in old frames – and old pictures in new frames – and remember that card mounts will transform even the most basic artwork. That old wardrobe might look fab with a new colour scheme, and your jaded bedroom chair will look great if you grab a few metres of fabric and wield that trusty staple gun. 5. New cushions and textiles will transform your existing sofa, whilst a change of linen will instantly alter your bedroom mood. Similarly, new towels and scented candles will transform your bathroom. 6. Shop smart via discount outlets, second hand stores and Facebook Marketplace, all of which are the C+J holy grail when looking for good deals. Be cognizant that second hand doesn't have to mean second best, and that 'previously enjoyed' is one of the best forms of recycling. This advertisement has not loaded yet, but your article continues below. 7. Don't be shy to ask for discounts. As we like to say; 'If you don't ask, you don't get.' Buy seasonally, research when big box stores have sales, and shop accordingly. 8. Interspersing lower cost items with indulgent items creates the impression that everything is similarly extravagant. We love the cut of Armani jackets, for example, and whilst they occupy the pricier end of our wardrobe, they're 'best value' on a 'dollars per wear' basis as they're rarely off our backs. Teamed with Old Navy jeans and crisp white shirts from Zara, the look is 100% high end. Whilst the foregoing example is sartorial, the same rules apply to the home, so use smoke 'n' mirrors and trick out your space on a budget. 9. Think 'double duty' bang for your buck. Choose padded storage cubes which make handy extra seating and buy reversible cushions and throws to change your look on a whim. And make sure you choose a coffee table that has in built secret stash zones for toys and magazines. This advertisement has not loaded yet, but your article continues below. 10. Get the look on a shoestring. Use replicas of the real thing (laminate 'wood' flooring instead of solid timber, or ceramic tiling instead of stone) to save cash without sacrificing aesthetics. As we've opined on myriad occasions, it's not how much is spent, rather how – and where – it's spent that transacts the biggest difference. *Cue imagery of two Scotsmen finding a penny, fighting over it tug of war style, and inadvertently inventing copper wire. Hey, we're not tight, we're just, em, careful. Watch for Colin and Justin on Citytv's Breakfast Television and Colin and Justin's Sub- Zero Reno on Paramount Plus TV. Find the Colin and Justin Home Collection in stores across Canada. Visit Sunshine Girls Columnists Toronto Maple Leafs Toronto & GTA World
CBC
06-06-2025
- Business
- CBC
Dramatic footage captures moment iconic Robertson Trading post burns in La Ronge, Sask.
Video from La Ronge, Sask., shows firefighting crews trying to save two businesses — Robertson Trading Post and Rona hardware store — using ground and aerial equipment. Both businesses were destroyed on June 3, 2025.
