Latest news with #Sanger


Miami Herald
27-07-2025
- Miami Herald
Accused drunk boater crashes into another boat, killing one, California cops say
A fatal collision between two boats on the Colorado River led to the arrest of a man accused of boating while intoxicated, California sheriff's officials reported. A 22-foot Cheetah deck boat crashed into an 18-foot Sanger vessel that was adrift on the river near Needles at 5:32 p.m. Friday, July 25, the San Bernardino County Sheriff's Office said in a news release. Weston Stewart, 38, who was on the 18-foot boat, suffered serious injuries in the collision, deputies said. Rescuers began CPR, but he was later pronounced dead at a hospital. Bruce Southworth, 43, who authorities say was operating the other boat, faces a charge of negligent use of a watercraft while intoxicated; causing injury, deputies said. An investigation into the crash continues. Detectives ask anyone with information to call 760-326-9200. Needles is about a 255-mile drive northeast from Los Angeles.


Business Wire
10-07-2025
- Health
- Business Wire
Sanger Sequencing of Borrelia burgdorferi flaB Gene Paralogs Can Detect a Single Bacterium for the Diagnosis of Lyme Disease Spirochetemia, Reported Milford Molecular Diagnostics Laboratory
MILFORD, Conn.--(BUSINESS WIRE)--Sin Hang Lee, M.D., director of Milford Molecular Diagnostics Laboratory in Milford, Conn., announces that the Borrelia burgdorferi spirochetes invading the blood stream of the patients at the early localized stage of Lyme disease have duplicate flaB gene paralogs in their chromosome. For Sanger sequencing-based diagnosis of Lyme disease spirochetemia, the flaB gene with its paralogs is a more sensitive chromosomal target than the 16S rRNA gene aiming to detect a single Borrelia burgdorferi bacterium in venous blood specimens, as reported in an article published in Frontier in Bioscience-Scholar The article emphasizes the importance of timely differential centrifugation of the whole blood specimens to isolate the platelet fraction, which contains the spirochetes, for DNA extraction because delayed centrifugation allows the highly mobile spirochetes to attach to and invade the lymphocytes in the test tube at ambient temperature, then to be lost in the buffy coat. These findings are based on a study of the platelet-rich plasma specimens from 145 people, including 98 symptomatic patients, residing in Lyme disease-endemic areas in the United States during a Lyme disease season in 2023. Based on the findings of this study, Dr. Lee has sent an open letter to the director of the Centers for Disease Control and Prevention urging the CDC to assist the hospital laboratories located in Lyme-disease endemic areas to implement methods to detect spirochetemia for early diagnosis and timely treatment of Borrelia burgdorferi infections Milford Molecular Diagnostics Laboratory is CLIA-certified. Its 'nested PCR and direct automated DNA sequencing-based method for qualitative detection/identification of Borrelia burgdorferi (Lyme disease) and Borrelia miyamotoi in whole blood specimens' is also approved by the New York State Department of Health for residents of the State of New York, said Dr. Lee. Healthcare providers and laboratories interested in DNA sequencing-based diagnosis of Lyme disease spirochetemia for their patients may obtain more information by contacting Milford Molecular Diagnostics Laboratory via


Wales Online
25-06-2025
- Wales Online
Eurostar passengers face delays after two tragic incidents
Eurostar passengers face delays after two tragic incidents Two separate incidents has caused widespread disruption to Eurostar services between London and Paris Eurostar passengers are facing delays (Image: Belga/AFP via Getty Images ) Eurostar passengers experienced delays of up to seven hours after two individuals were tragically struck by trains. The distressing incident on Tuesday caused significant disruption for those travelling between London St Pancras International and Gare Du Nord in Paris, with many journeys cancelled entirely. The operator warned that the disruption was expected to continue on Wednesday, June 25. "Due to two persons struck by trains near Lille Europe, we've delays and cancellations to our services all evening," Eurostar announced on X, adding: "We apologise to everyone affected and advise changing your journey for a different travel date." Services between London and Paris were suspended shortly after 3pm. One train, scheduled to arrive in Paris before 6pm, was still navigating the tunnels in northern France at 9.45pm, as reported by the Telegraph. These delays followed two separate incidents; the first reportedly occurred between Lille and Paris around 5pm, and the second between Lille and Arras, according to local media, reports Yorkshire Live. This morning, Eurostar cautioned via X that while trains will be running today, there are a "few cancellations" and "a lot of passengers travelling." Article continues below It added: "So the situation might still be difficult." Eurostar has been left with no choice but to axe multiple train services - specifically the 9007, 9013, 9023, 9008, and 9018 - owing to a perfect storm of issues afflicting the rail network. For our free daily briefing on the biggest issues facing the nation, sign up to the Wales Matters newsletter here Passengers are reeling from the consequences of yesterday's disruption and hold-ups at railway stations in the UK and France, only to have their woes worsened by the theft of a vital cable close to Lille. Travellers expecting to board trains scheduled for 4.01pm, 6.01pm, and 8.01pm today have been hit by severe delays and cancellations, leading to a chorus of discontent on social media, with many now demanding refunds. A distraught passenger vented on social media: "I've been on the 9032 for seven hours and we're still not in Paris," inquiring, "Will we get full compensation?" Another disgruntled commuter threatened: "I'm going to need my full ticket refunded plus compensation. Five hours on board and now another three-hour delay." As the situation continues to unfold, passenger Naomi Sanger revealed to KentOnline how her 4.31pm train out of Paris's Gare Du Nord station failed to depart, deserting her at the station. Taking to the social media platform X, Ms. Sanger disclosed dwindling resources, including food and water, as well as the station's struggling air conditioning system. This current turmoil is not the only issue to impact Eurostar recently on Wednesday, June 14. Article continues below A tragic fatality on a French railway line occurred on leading to nearly a dozen Eurostar services facing significant delays or outright cancellations on that same route.


Economic Times
28-05-2025
- Entertainment
- Economic Times
Burnt ends: Singapore
At Burnt Ends, chef Dave Pynt brings fire and finesse to the table - literally. Known for its modern Australian barbecue, this Michelin-starred hotspot in Singapore revolves around an open-concept wood-fired oven, where ingredients are grilled, smoked and kissed with flame until they reach smoky, caramelised perfection. The Sanger is the crowd favourite for good reasons. A generous heap of pulled pork shoulder is tucked into a fluffy brioche bun, slathered with chipotle aioli and topped with crunchy coleslaw. It's messy, meaty and satisfying - every bite balances richness with spice. For something lighter, consider the smoked quail eggs or the beef marmalade toast, both showcasing Pynt's clever use of smoke and texture. Dessert may seem like an afterthought at a place known for barbecue. But the Marshmallow is unmissable. Torched until golden with a charred exterior, it's creamy, sweet and delicately smoky, with a surprising but welcome hint of orange. Whether you're there for a long lunch or a quick indulgence, Burnt Ends serves up fire-powered comfort with sophistication. One visit, and you'll understand why the queues form before the doors even open.


Time of India
28-05-2025
- Entertainment
- Time of India
Burnt ends: Singapore
At Burnt Ends, chef Dave Pynt brings fire and finesse to the table - literally. Known for its modern Australian barbecue , this Michelin-starred hotspot in Singapore revolves around an open-concept wood-fired oven , where ingredients are grilled, smoked and kissed with flame until they reach smoky, caramelised Sanger is the crowd favourite for good reasons. A generous heap of pulled pork shoulder is tucked into a fluffy brioche bun, slathered with chipotle aioli and topped with crunchy coleslaw. It's messy, meaty and satisfying - every bite balances richness with spice. For something lighter, consider the smoked quail eggs or the beef marmalade toast, both showcasing Pynt's clever use of smoke and may seem like an afterthought at a place known for barbecue. But the Marshmallow is unmissable. Torched until golden with a charred exterior, it's creamy, sweet and delicately smoky, with a surprising but welcome hint of orange. Whether you're there for a long lunch or a quick indulgence, Burnt Ends serves up fire-powered comfort with sophistication. One visit, and you'll understand why the queues form before the doors even open.