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Shubhanshu Shukla's space research could transform diabetes care on Earth
Shubhanshu Shukla's space research could transform diabetes care on Earth

Time of India

time04-07-2025

  • Health
  • Time of India

Shubhanshu Shukla's space research could transform diabetes care on Earth

Indian astronaut Shubhanshu Shukla is currently aboard the International Space Station, having launched on June 25, 2025, as part of the Axiom Mission 4 (Ax-4). He is involved in pioneering research aimed at transforming how diabetes is monitored and managed in space. In collaboration with Axiom Space and Burjeel Holdings, the experiment focuses on testing Continuous Glucose Monitors (CGMs) and insulin technologies in microgravity. Known as the "Suite Ride" project, this study could pave the way for safer space travel for people with diabetes and also bring new solutions to diabetes care on Earth, especially in remote or underserved areas. With global diabetes cases on the rise, the mission holds promise for both space medicine and everyday healthcare. What the 'Suite Ride' project of Axiom-4 is doing in space The Suite Ride project is testing the use of CGMs, devices that track blood glucose levels in real time, during spaceflight. One or more astronauts on the Ax-4 mission are wearing CGMs for the full two-week duration. The devices are sending data back to Earth to evaluate their accuracy and stability in microgravity. Insulin pens were also sent to the International Space Station, although the astronauts are not using them. The goal is to see how well insulin maintains its potency in space. Blood samples are being collected and analyzed with specialized equipment, all provided by Burjeel Holdings, to compare results and validate the technology. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like 21st Century Skills Start with Confident Communication Planet Spark Learn More Undo Why microgravity offers a unique research opportunity Microgravity creates a different physiological environment, allowing scientists to study the human body in ways that are not possible on Earth. Changes in fluid distribution, muscle mass, and sleep cycles may influence how the body regulates blood sugar and responds to insulin. This could help researchers identify new markers of insulin resistance and understand diabetes at a deeper level. The research also builds on previous findings from missions like Galactic 07, which showed that commercial insulin pens can function in space within international medical standards. How this could change lives on Earth While the long-term goal is to make it possible for astronauts with diabetes to join space missions safely, the benefits of this research are equally valuable on Earth. If CGMs and insulin storage solutions can work reliably in space, they can be adapted for use in harsh or remote locations such as deserts, oil platforms, and rural clinics. Dr. Mohammad Fityan, Chief Medical Officer at Burjeel Holdings, explained that space serves as a testing ground for technologies that could enhance healthcare delivery in low-access regions. With diabetes rising rapidly in areas like the MENA region, where it is expected to increase by 87 percent by 2045, there is a growing need for innovation. What comes next in the research timeline After the mission concludes, researchers will study the collected data to assess how CGMs and insulin performed under space conditions. If the findings are promising, future missions may include astronauts with non-insulin-dependent Type 2 diabetes, followed by those with insulin-dependent diabetes. Dr. Mike Harrison from Axiom Space said this mission is not just about scientific progress in orbit. It is about improving healthcare access on Earth and making space more inclusive for people with chronic conditions. The success of this project could help rewrite the rules of both diabetes care and human spaceflight, bringing us closer to a world where health challenges no longer limit the possibilities of exploration.

Shubhanshu Shukla's space mission could rewrite the rules of diabetes care. Here's how
Shubhanshu Shukla's space mission could rewrite the rules of diabetes care. Here's how

India Today

time02-07-2025

  • Health
  • India Today

Shubhanshu Shukla's space mission could rewrite the rules of diabetes care. Here's how

Indian astronaut Shubhanshu Shukla is currently part of a historic mission aboard the International Space Station (ISS), participating in over 60 scientific experiments as part of the Axiom Mission 4 (Ax-4). Among them is a study that could reshape how we understand and manage diabetes: not just in space, but also on years, people with insulin-dependent diabetes have been excluded from space missions because of the challenges of managing blood sugar levels in a zero-gravity environment. The Ax-4 mission is now rethinking that 'SUITE RIDE' PROJECT: A STEP TOWARD INCLUSION A major highlight of the Ax-4 mission is a research project called Suite Ride, designed to study how glucose metabolism is affected by ultimate goal is to make it safe for people with diabetes to live and work in space."Suite Ride is investigating how the space environment affects glucose metabolism in the human body. This can enhance our understanding of diabetes and other metabolic diseases that impact blood sugar regulation," Dr. Mohammad Fityan, Clinical Lead for the Suite Ride project (Ax-4) from Burjeel Holdings, Chief Medical Officer, Burjeel Medical City, told Dr. Mohammad Fityan (right), Clinical Lead of the Burjeel–Ax-4 Space Health Research, with Gavin D'Elia (L), Global Head Of Pharma at Axiom Space and Dr. Lucie Low, Chief Scientist for Axiom Space at Kennedy Space Center. advertisementBurjeel Holdings, the research collaborator behind the project, partnered with Axiom Space to explore how Continuous Glucose Monitors (CGMs) and insulin fare in space. These tools are already revolutionising diabetes care on SPACE IS A GAME-CHANGER FOR DIABETES RESEARCHMicrogravity provides an environment that allows scientists to study the body without the usual gravitational pressures. This makes it possible to observe glucose metabolism in an entirely new light."Microgravity allows us to study metabolism without the influence of gravity. Changes in muscle mass, fluid distribution, and circadian rhythm offer new insights into glucose metabolism and insulin sensitivity. This may lead to the identification of novel pathways and early biomarkers for insulin resistance," said Dr. studying healthy individuals in space, scientists can create a foundation for understanding how diabetes behaves in such conditions, an essential step toward future space travel for those with chronic THE STUDY WORKS ABOARD ISSDuring the two-week mission, one or more astronauts are wearing CGMs for the entire duration. These devices continuously monitor blood glucose levels and send data back to Earth. The Ax-4 crew members aboard the International Space Station. (Photo: Nasa) "One or more astronauts are wearing CGMs for the entire duration of the mission. Readings are continuously monitored, and data is being collected. Insulin pens were sent on the flight, but astronauts are not using them. We are testing the viability and stability of insulin in the space environment. Point-of-care blood samples are also being taken during the mission to validate glucose levels. Lancets, needles, and blood glucose analyzers (i-STAT) were provided by Burjeel Holdings," said Dr. BARRIERS FOR DIABETICS IN SPACEDr. Fityan explained the current barriers that keep people with diabetes from going to space:Glucose variability and hypoglycemia can be life-threatening in space, where immediate medical help isn't challenges due to storage temperatures, fluid shifts, and inconsistent absorption in need for extremely accurate glucose control, which is hard to maintain on long Ax-4 mission is helping scientists understand how healthy metabolism behaves in microgravity and whether CGMs can be safely used by astronauts with diabetes in future CARE ON EARTHThe findings from Ax-4 are not just for future astronauts. They could also benefit people on Earth, especially in remote or underserved areas. advertisementThis study could lead to:Remote monitoring platforms for real-time metabolic glucose monitors for extreme or low-resource predictive models for personal diabetes drug targets to improve insulin sensitivity."This research helps expand eligibility for spaceflight, not by lowering standards, but by creating technologies and protocols that enable safe participation for individuals with chronic conditions, such as insulin-dependent diabetes," Dr. Fityan told NEXT?Once the mission returns, researchers will analyse the data to determine the next steps."We hope this research opens the door to future studies, including sending the first astronaut with diabetes into space and exploring other metabolic and chronic conditions," said Dr. Ax-4 mission, with Shubhanshu Shukla on board, could mark a historic event, one where space is accessible even for those managing chronic conditions like diabetes, and where the lessons from above help save lives back on Earth.- EndsTune InMust Watch

UAE-led diabetes research initiative embarks on space mission
UAE-led diabetes research initiative embarks on space mission

Al Etihad

time25-06-2025

  • Health
  • Al Etihad

UAE-led diabetes research initiative embarks on space mission

25 June 2025 22:55 SREENIVASA REDDY (ABU DHABI)In a milestone for the UAE's scientific aspirations, a pioneering healthcare research initiative has been launched into space aboard Axiom Space's Ax-4 mission, which took off from Kennedy Space Centre in Florida after several delays. Central to the mission is Suite Ride, a novel research effort developed in partnership between Abu Dhabi-based Burjeel Holdings and Axiom Space, aiming to redefine the potential of space travel for individuals living with insulin-dependent diabetes mellitus (IDDM)—a condition previously seen as incompatible with Ax-4 mission has now set course for the International Space Station (ISS), where its four-member international crew will undertake 14 days of scientific work in microgravity. Their agenda includes conducting technology demonstrations and biomedical research that promise to advance knowledge across multiple Suite Ride study is designed to test the effectiveness of Continuous Glucose Monitors (CGMs)—now standard for diabetes management—under conditions of microgravity. These monitors will collect real-time glucose data throughout the mission, with comprehensive protocols spanning the preflight, inflight and postflight phases. In addition, the mission will examine how insulin behaves in space, evaluating its stability and potency after the scientific component of the project is Dr Mohammad Fityan, Chief Medical Officer at Burjeel Medical City and Clinical Lead for the Burjeel–Ax-4 Space Health Research. Working closely with Axiom Space's team, Dr Fityan will analyse CGM data to understand how these technologies perform in orbit, with the aim of translating the findings into practical healthcare solutions on Earth.'After months of preparation, we're excited to see our research project take flight aboard Ax-4. We're confident that the valuable insights gained will help improve healthcare access in underserved and hard-to-reach communities around the world, including in the MENA region,' said Dr commemorate the occasion, Burjeel Medical City is hosting a special exhibition highlighting the Suite Ride initiative, offering the UAE public and scientific circles an opportunity to engage with the broader implications of space health research. The UAE Embassy in Washington, D.C. also recently featured the project as a notable milestone in the country's growing role in human the Suite Ride mission is taking place against the backdrop of a steep rise in diabetes prevalence. The International Diabetes Federation projects 783 million cases by 2045, with the MENA region expected to see an 87% increase—underlining the urgent need for advanced remote healthcare technologies. Commanded by NASA astronaut Peggy Whitson, the Ax-4 mission crew includes Mission Pilot Shubhanshu Shukla (India) and Mission Specialists Sławosz Uznański-Wiśniewski (ESA/Poland) and Tibor Kapu (Hungary). Collectively, they are set to conduct over 60 experiments sourced from 31 countries.

Diabetes To Methi & Moong Dal: Axiom 4 Will Help ISRO Study These Things
Diabetes To Methi & Moong Dal: Axiom 4 Will Help ISRO Study These Things

News18

time25-06-2025

  • Health
  • News18

Diabetes To Methi & Moong Dal: Axiom 4 Will Help ISRO Study These Things

Last Updated: Axiom Mission 4: NASA and Indian Space Research Organisation (ISRO) are collaborating to launch several scientific investigations The Axiom Mission 4, including Indian astronaut Shubhanshu Shukla which was launched on Wednesday, is set to conduct major research, including 60 scientific studies and activities representing 31 countries, including the US, India, Poland, Hungary, Saudi Arabia, Brazil, Nigeria, UAE, and nations across Europe. The research will cover space agriculture (e.g. methi, moong daal), tardigrade biology, muscle loss prevention, glucose regulation (Suite Ride diabetes study), cognitive/computer interaction, and more. This will be the most research and science-related activities conducted on an Axiom Space mission aboard the International Space Station to date. NASA and ISRO (Indian Space Research Organisation) are collaborating to launch several scientific investigations. These studies include examining muscle regeneration, growth of sprouts and edible microalgae, survival of tiny aquatic organisms, and human interaction with electronic displays in microgravity. WHAT ISRO WILL STUDY The Axiom-4 mission also sets the tone for ISRO's own Gaganyaan Mission, a project to send a 3-day manned mission to the Low Earth Orbit (LEO) of 400 km with a crew of three members and bring them safely back to Earth. Shukla's Axiom-4 mission is set to offer a ray of hope for diabetics to travel to space, as a UAE-based healthcare provider is conducting an experiment on how glucose behaves in microgravity conditions. As part of the 'Suite Ride" experiment planned by Burjeel Holdings and Axiom Space, some astronauts of the Axiom-4 mission will be wearing continuous glucose monitors during their 14-day stay on board the orbital lab. The studies of the behaviour of glucose and insulin in microgravity conditions will help scientists develop wearable technologies for astronauts and patients who are bedridden or have limited mobility due to illnesses such as paralysis. 'We are trying just to see if there is any change or fluctuation to the blood-sugar levels while they are in space," Mohammad Fityan, chief medical officer at Burjeel Holdings, Abu Dhabi, told PTI. The astronauts will also carry insulin pens in refrigerated and ambient temperatures to examine how the molecules respond to microgravity conditions. Currently, the National Aeronautics and Space Administration (NASA) does not allow insulin-dependent diabetics to travel to space. There are no official exclusions for non-insulin-dependent diabetics, but so far, no astronaut with diabetes has travelled to space. With PTI, ANI Inputs Get Latest Updates on Movies, Breaking News On India, World, Live Cricket Scores, And Stock Market Updates. Also Download the News18 App to stay updated! tags : deep space ISRO nasa Location : New Delhi, India, India First Published: June 25, 2025, 12:01 IST News explainers Diabetes To Methi & Moong Dal: Axiom 4 Will Help ISRO Study These Things | Explained

Axiom-4 astronauts to study insulin behaviour in microgravity, revolutionise diabetes treatment
Axiom-4 astronauts to study insulin behaviour in microgravity, revolutionise diabetes treatment

Time of India

time21-06-2025

  • Health
  • Time of India

Axiom-4 astronauts to study insulin behaviour in microgravity, revolutionise diabetes treatment

New Delhi: Indian astronaut Shubhanshu Shukla's Axiom-4 mission to the International Space Station (ISS) is set to offer a ray of hope for diabetics to travel to space, as a UAE-based healthcare provider is conducting an experiment on how glucose behaves in microgravity part of the "Suite Ride" experiment planned by Burjeel Holdings and Axiom Space, some astronauts of the Axiom-4 mission will be wearing continuous glucose monitors during their 14-day stay on board the orbital lab. The studies of the behaviour of glucose and insulin in microgravity conditions will help scientists develop wearable technologies for astronauts and patients who are bedridden or have limited mobility due to illnesses such as paralysis. "We are trying just to see if there is any change or fluctuation to the blood-sugar levels while they are in space," Mohammad Fityan, chief medical officer at Burjeel Holdings, Abu Dhabi, told PTI. The astronauts will also carry insulin pens in refrigerated and ambient temperatures to examine how the molecules respond to microgravity conditions. "We are hoping that if we learn something about the metabolism or the effect, we will bring some information and we can do something for our patients on Earth," Fityan said. Currently, the National Aeronautics and Space Administration (NASA) does not allow insulin-dependent diabetics to travel to space. There are no official exclusions for non-insulin-dependent diabetics, but so far, no astronaut with diabetes has travelled to space. "It has the potential to transform the future of space travel for astronauts with insulin-dependent diabetes mellitus (IDDM), a condition historically considered disqualifying for space missions," Fityan said. He said the study will pave the way for several innovative technologies and treatment approaches for developing advanced glucose-monitoring tools optimised for extreme or low-activity environments, improving wearable tech for both astronauts and patients with limited mobility on Earth. It will also help identify new pharmacologic targets by observing how metabolic and hormonal responses change in microgravity, leading to drugs that enhance insulin sensitivity or mimic the benefits of exercise in sedentary individuals. The AI-powered predictive models based on real-time physiologic data in space can be adapted to personalise diabetes care on Earth by forecasting insulin needs or metabolic shifts with higher accuracy. The research will also help develop remote monitoring platforms for continuous metabolic-data capture that could revolutionise diabetes care in underserved or remote areas on Earth as well as in tele-health settings.

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