Latest news with #TC
Yahoo
17 hours ago
- Health
- Yahoo
400 Women Are Suing Pfizer Over Birth Control Shot That Allegedly Gave Them Brain Tumors
Recent research has linked Pfizer's widely-used Depo-Provera birth control shot to massively increased risk of developing brain tumors — and hundreds of women are suing the pharmaceutical giant over it. According to a press release filed on behalf of the roughly 400 plaintiffs in the class action suit, the lawsuit claims that Pfizer and other companies that made generic versions of the injectable contraceptive knew of the link between the shot and the dangerous tumors, but didn't properly warn users. The suit follows a study published by the British Medical Journal last year that found that people who took the progestin-based shot for a year or more were up to 5.6 times more likely to develop meningioma, a slow-building brain tumor that forms, per the Cleveland Clinic, on the meninges, or layers of tissue that covers the brain and spinal cord. Though Pfizer attached warning labels about meningioma to Depo-Provera sold in Canada in 2015 and the UK, Europe, and South Africa after the 2024 study was published, no such label was deployed in the United States — a failure which according to the lawsuit is "inconsistent [with] global safety standards." In an interview with the website DrugWatch, one of the suit's plaintiffs, who was identified by the initials TC, said that she had been "told how great Depo-Provera was" and decided to start it after an unplanned pregnancy that occurred when she'd taken the since-discontinued birth control pill Ortho Tri-Cyclen Lo. "I thought it would be more reliable and convenient since I wouldn't have to take it daily," TC told the site, referencing the four annual injections Depo-Provera requires. "I had no idea it would lead to such serious health problems." After being on the contraceptive shot for three years — and experiencing intense headaches, months-long uterine bleeding, and weight gain — the woman finally consulted her doctor and was diagnosed with meningioma. She's since been undergoing treatment and experienced some relief, but even that experience has been "physically and emotionally draining" because she has to get regular MRIs to monitor the tumor, which likely isn't fatal but still greatly affects her quality of life. "It's a constant worry that the tumor might grow," TC said, "and the appointments feel never-ending." That fear was echoed by others who spoke to the Daily Mail about their meningioma diagnoses after taking Depo-Provera. Unlike TC, Andrea Faulks of Alabama hadn't been on the shots for years when she learned of her brain tumors, which caused her years of anguish. Faulks told the British website that she'd begun taking the medication back in 1993, the year after it was approved by the FDA in the United States. She stopped taking it only a few years later, but spent decades having splitting headaches and experiencing dizziness and tremors. After being dismissed by no fewer than six doctors, the woman finally got an MRI last summer and learned that she had a brain tumor — and is now undergoing radiation to shrink it after all this time. "I know this is something I'm going to have to live with for the rest of my life, as long as I live," Faulks told the Daily Mail. Currently, the class action case against Pfizer on behalf of women like Faulks and TC is in its earliest stages as attorneys representing those hundreds of women with brain tumors start working to make them whole. Even if they receive adequate payouts, however, that money won't take away their suffering, or give them back the years of their life lost to tumors they should have been warned about. More on injectables: This Sleazy GLP-1 Prescription Site Is Using Deepfaked "Before-and-After" Photos of Fake Patients, and Running Ads Showing AI-Generated Ozempic Boxes
The Sun
3 days ago
- Business
- The Sun
Arup experts share trends shaping the future of rail at Asia Pacific Rail
HONG KONG SAR - Media OutReach Newswire - 29 May 2025 - Rail leaders of global sustainable development consultancy Arup from across the Asia Pacific region shared their insights into the future of rail at Asia Pacific Rail 2025, ranging from the role of transit-oriented development in funding rail infrastructure, the use of the latest green and smart technology in transit systems, station transformation, and customer journey planning. Held in Bangkok on 28-29 May 2025, the major rail event in the region was attended by 4,000 people and brought together more than 160 speakers and 200 exhibitors. As moderator of the keynote panel, TC Chew, Managing Director of APAC at Arup, discussed with leaders of key rail organisations in the region the crucial role of Transit-Oriented Development (TOD) in making public-private partnerships (PPPs) financially viable and sustainable, the challenges in implementing TOD as well as opportunities for future regional collaboration. 'Governments are under increasing pressure to look for innovative ways to fund rail projects. TOD could be part of the answer. If planned and designed carefully, TOD can help address challenges such as a growing population and demand for housing and employment, while promoting efficient transport options needed for a long-term sustainable future,' said TC. James Musgrave, APAC Rail Business Leader at Arup, said, 'From the Kowloon Station development in Hong Kong to the Sydney Metro Martin Place integrated station development in Australia, Arup provided strategic planning, design and engineering expertise to maximise the value of investment in transit infrastructure and the positive impact on the community it serves. When we create an impactful TOD, we don't just change how a city moves, we redefine how people live.' Three leaders from Arup also spoke at Asia Pacific 2025 on major topics in railway development: • Alberto Battois, Malaysia Rail Business Leader, on 'Integrated mobility – what next?'; • Carol Lau, Associate Director, on 'New forms of smart and green mass transit systems for medium capacity network - planning and design'; and • Aden Chua, Associate, on 'Digitalising station transformation'. In addition, Arup sponsored the British Embassy Reception, where Arup's clients and partners connected with rail leaders to exchange ideas and share insights. With over 6,400 people in 28 offices across Asia Pacific and direct access to a larger global network, Arup is committed to supporting clients to deliver transformative railways that enhance lives and connectivity across cities and nations.
Associated Press
4 days ago
- Business
- Associated Press
Arup experts share trends shaping the future of rail at Asia Pacific Rail
HONG KONG SAR - Media OutReach Newswire - 29 May 2025 - Rail leaders of global sustainable development consultancy Arup from across the Asia Pacific region shared their insights into the future of rail at Asia Pacific Rail 2025, ranging from the role of transit-oriented development in funding rail infrastructure, the use of the latest green and smart technology in transit systems, station transformation, and customer journey planning. Arup experts gathered at Asia Pacific Rail 2025, exploring how to transform rail across the region. Held in Bangkok on 28-29 May 2025, the major rail event in the region was attended by 4,000 people and brought together more than 160 speakers and 200 exhibitors. As moderator of the keynote panel, TC Chew, Managing Director of APAC at Arup, discussed with leaders of key rail organisations in the region the crucial role of Transit-Oriented Development (TOD) in making public-private partnerships (PPPs) financially viable and sustainable, the challenges in implementing TOD as well as opportunities for future regional collaboration. 'Governments are under increasing pressure to look for innovative ways to fund rail projects. TOD could be part of the answer. If planned and designed carefully, TOD can help address challenges such as a growing population and demand for housing and employment, while promoting efficient transport options needed for a long-term sustainable future,' said TC. James Musgrave, APAC Rail Business Leader at Arup, said, 'From the Kowloon Station development in Hong Kong to the Sydney Metro Martin Place integrated station development in Australia, Arup provided strategic planning, design and engineering expertise to maximise the value of investment in transit infrastructure and the positive impact on the community it serves. When we create an impactful TOD, we don't just change how a city moves, we redefine how people live.' Three leaders from Arup also spoke at Asia Pacific 2025 on major topics in railway development: In addition, Arup sponsored the British Embassy Reception, where Arup's clients and partners connected with rail leaders to exchange ideas and share insights. With over 6,400 people in 28 offices across Asia Pacific and direct access to a larger global network, Arup is committed to supporting clients to deliver transformative railways that enhance lives and connectivity across cities and nations. Hashtag: #Rail #TransitOrientedDevelopment #Arup Wechat: Arup奥雅纳 The issuer is solely responsible for the content of this announcement. Arup Arup is a global built environment consultancy with advisory and technical expertise across more than 150 disciplines. We create safe, resilient, and regenerative places, bringing a Total Design approach to our work for our clients.
Arabian Post
4 days ago
- Business
- Arabian Post
Arup experts share trends shaping the future of rail at Asia Pacific Rail
Arup experts gathered at Asia Pacific Rail 2025, exploring how to transform rail across the region. HONG KONG SAR – Media OutReach Newswire – 29 May 2025 – Rail leaders of global sustainable development consultancy Arup from across the Asia Pacific region shared their insights into the future of rail at Asia Pacific Rail 2025, ranging from the role of transit-oriented development in funding rail infrastructure, the use of the latest green and smart technology in transit systems, station transformation, and customer journey planning. Held in Bangkok on 28-29 May 2025, the major rail event in the region was attended by 4,000 people and brought together more than 160 speakers and 200 exhibitors. As moderator of the keynote panel, TC Chew, Managing Director of APAC at Arup, discussed with leaders of key rail organisations in the region the crucial role of Transit-Oriented Development (TOD) in making public-private partnerships (PPPs) financially viable and sustainable, the challenges in implementing TOD as well as opportunities for future regional collaboration. ADVERTISEMENT 'Governments are under increasing pressure to look for innovative ways to fund rail projects. TOD could be part of the answer. If planned and designed carefully, TOD can help address challenges such as a growing population and demand for housing and employment, while promoting efficient transport options needed for a long-term sustainable future,' said TC. James Musgrave, APAC Rail Business Leader at Arup, said, 'From the Kowloon Station development in Hong Kong to the Sydney Metro Martin Place integrated station development in Australia, Arup provided strategic planning, design and engineering expertise to maximise the value of investment in transit infrastructure and the positive impact on the community it serves. When we create an impactful TOD, we don't just change how a city moves, we redefine how people live.' Three leaders from Arup also spoke at Asia Pacific 2025 on major topics in railway development: Alberto Battois, Malaysia Rail Business Leader, on 'Integrated mobility – what next?'; Carol Lau, Associate Director, on 'New forms of smart and green mass transit systems for medium capacity network – planning and design'; and Aden Chua, Associate, on 'Digitalising station transformation'. In addition, Arup sponsored the British Embassy Reception, where Arup's clients and partners connected with rail leaders to exchange ideas and share insights. With over 6,400 people in 28 offices across Asia Pacific and direct access to a larger global network, Arup is committed to supporting clients to deliver transformative railways that enhance lives and connectivity across cities and nations. Hashtag: #Rail #TransitOrientedDevelopment #Arup Wechat: Arup奥雅纳 The issuer is solely responsible for the content of this announcement. Arup Arup is a global built environment consultancy with advisory and technical expertise across more than 150 disciplines. We create safe, resilient, and regenerative places, bringing a Total Design approach to our work for our clients.
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Business Standard
21-05-2025
- Health
- Business Standard
Broken heart syndrome: Men face twice the death risk, say researchers
Have you ever felt like your heart is actually breaking from grief, loss or emotional shock? Science now says there might be more truth to that feeling than you think—especially for men. A recent large-scale study titled High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men, published in the J ournal of the American Heart Association, reveals that men are more than twice as likely to die from a condition widely known as 'broken heart syndrome'—medically called Takotsubo cardiomyopathy (TC). What exactly is Takotsubo cardiomyopathy? Takotsubo cardiomyopathy is a temporary heart condition triggered when emotional or physical stress causes the heart's main pumping chamber to change shape and weaken. It mimics a heart attack but without blocked arteries. The name 'Takotsubo' comes from a Japanese octopus trap, which the affected heart chamber resembles when ballooned. This syndrome is most commonly set off by emotional trauma such as the death of a loved one, a breakup or severe shock following surgery or accidents. What did the study reveal about gender-based differences? Researchers analysed data from nearly 200,000 adult patients hospitalised with Takotsubo cardiomyopathy in the US between 2016 and 2020. Although 83 per cent of those diagnosed were women, men had a significantly higher in-hospital death rate. What complications are linked to broken heart syndrome? Takotsubo cardiomyopathy can result in serious complications. According to the study: 35.9 per cent developed congestive heart failure 20.7 per cent had atrial fibrillation 6.6 per cent experienced cardiogenic shock 5.3 per cent suffered a stroke 3.4 per cent went into cardiac arrest These complications significantly increase mortality risk—especially in men—and may leave lasting effects even after recovery. Why are men more vulnerable despite lower diagnosis rates? There are several reasons men may face higher mortality from this condition: Underdiagnosis: Historically considered a 'woman's condition', TC may be missed or misdiagnosed in men Physical stress triggers: Men are more likely to experience physical rather than emotional stress, which may indicate more severe underlying illnesses Hormonal factors: Oestrogen in women is believed to provide some protective effect against stress-induced cardiac events The study recommends more focused research to understand these disparities and improve diagnosis and care pathways for men. Is the condition becoming more common across age groups? Yes. Hospitalisations related to Takotsubo cardiomyopathy have increased steadily from 2016 to 2020, especially among those aged 46–60. The rise may reflect better awareness and diagnosis but could also point to growing levels of emotional and physical stress in modern life. How can emotional stress lead to cardiac complications? The connection between emotional distress and cardiac health is well established. For women, emotional trauma is often the primary trigger. For men, physical stress—such as infection or surgery—is more commonly the cause. Physical triggers are often associated with worse outcomes, helping explain the gender-based disparity in death rates. What can individuals do to reduce the risk? While stress cannot always be avoided, steps can be taken to reduce its impact on heart health: Speak openly about your emotions—don't internalise distress Seek help after trauma or loss—professional therapy matters Adopt stress-management habits such as exercise, meditation and rest Monitor physical health closely, especially if you have pre-existing heart risks Why emotional health is heart health This study underscores that emotional health isn't just a mental wellness issue—it has tangible effects on cardiovascular health. Men in particular must be more aware, as their symptoms may be overlooked and their outcomes worse.
