Latest news with #VitaminD3
Business Standard
15 hours ago
- Business
- Business Standard
Fermenta Announces Granting of CEP by EDQM for VITADEE™ 100 SD, Enabling Accelerated Global Growth
PRNewswire Thane (Maharashtra) [India], July 30: Fermenta Biotech Limited ("Fermenta"), a pioneer in pharmaceutical and nutritional ingredients; one of the world's leading manufacturers of Vitamin D3, is pleased to announce that it has received the Certificate of Suitability (CEP) by the European Directorate for the Quality of Medicines & Healthcare (EDQM) for its Spray-Dried variant, VITADEE™ 100 SD - CHOLECALCIFEROL CONCENTRATE (POWDER FORM) 100, 000 IU/g being manufactured at its Kullu, Himanchal Pradesh facility. Fermenta now becomes one of the only two companies globally to hold a CEP for this variant of Vitamin D3. The approval underscores Fermenta's adherence to the stringent European Pharmacopoeial Standards for manufacturing and product quality. Commenting on the achievement, Mr Prashant Nagre, Managing Director of Fermenta, shared: "As we enter our 75th year, receiving the CEP for VITADEE™ 100 SD marks a significant milestone for Fermenta. It reinforces our commitment to the benchmarks of regulatory compliance by growing our product portfolio whilst strengthening our position as an established global partner in the field of Vitamin D3. This accreditation also enables us to move further up the value chain and stands as yet another testament to our focus on excellence, innovation, and trust." This recognition further enhances Fermenta's international footprint and our capability to deliver products that meet the highest global quality and regulatory standards. It represents another step forward in our mission to expand our global presence and create meaningful impact across the health and nutrition industry. About Fermenta Biotech Limited : Founded in 1951, Fermenta Biotech Limited (Fermenta) possesses a growing portfolio of nutrition including Customized Premixes, Fortified Rice Kernel (FRK) and other nutritional ingredients. Apart from its nutrition portfolio, Fermenta is one of the world's leading manufacturers of Vitamin D3. It caters to over 400 customers across 60 countries with a worldwide distribution network for a variety of applications such as pharmaceuticals, dietary and nutritional supplements, food, animal nutrition and rodenticides. Fermenta's manufacturing facilities in Kullu, Dahej and Tirupati are certified by global accreditations, and its world class R & D centre is located at Thane. Fermenta also possesses expertise in green chemistry such as enzymes for antibiotic synthesis, other niche APIs and environmental solutions. For more information about Fermenta and its business, please visit our website Safe Harbor : Statements in this document relating to future status, events, or circumstances, including but not limited to statements about plans and objectives, the progress and results of research and development, potential project characteristics, project potential and target dates for project related issues are forward-looking statements based on estimates and the anticipated effects of future events on current and developing circumstances. Such statements are subject to numerous risks and uncertainties and are not necessarily predictive of future results. Actual results may differ materially from those anticipated in the forward-looking statements. Fermenta assumes no obligation to update forward-looking statements to reflect actual results, changed assumptions or other factors.
Time of India
4 days ago
- Health
- Time of India
Feeling low, weak or have constant body pain? Vitamin D might be to blame: Try this trio that every expert would agree on
There's something about sunlight that makes everything feel a little better. But behind that warm glow lies a nutrient with great power, Vitamin D3. It's called the 'sunshine vitamin,' but calling it just that sells it short. Tired of too many ads? go ad free now Because in reality, Vitamin D3 behaves more like a hormone than a simple nutrient. It influences the bones, immune system, mood, and even heart health. But here's the twist, D3 can't do its job alone. Without the right support team, even a daily supplement or dose of sunshine might not work as expected. This is the story of Vitamin D3, and the quiet heroes that help it shine. The real role of vitamin D3 Vitamin D3 helps the body absorb calcium, something that's crucial for healthy bones. That much is widely known. But what's less talked about is its role in immune function, brain health, and even mental clarity. It supports the immune system in recognising threats more efficiently and may help reduce the risk of infections. Some early research also hints at its involvement in reducing the risk of autoimmune conditions and mood disorders like depression. So yes, while D3 is vital for bones, it's also quietly guarding other corners of the body. The calcium traffic controller no one talks about There's a surprising fact about calcium: it doesn't always know where to go. And that's where Vitamin K2 steps in. It acts like a GPS, guiding calcium to the bones and teeth, where it strengthens structure, and keeping it away from arteries and soft tissues, where it could cause harmful buildup. A lack of K2 can mean that calcium ends up where it doesn't belong, contributing to stiff arteries and heart-related issues. That's why K2 is often paired with D3 in smart supplementation plans. On its own, D3 increases calcium absorption, but without K2, that calcium may wander. Why is magnesium important? Here's a truth that surprises many: Vitamin D3 can remain 'inactive' in the body if magnesium levels are too low. In simple terms, without magnesium, the body can't activate D3 to do its work. Tired of too many ads? go ad free now And magnesium isn't just an assistant. It also supports over 300 enzyme reactions, influences mood, muscle relaxation, and helps with quality sleep. Low magnesium can lead to fatigue, irritability, and restless nights, signs that are often blamed on stress but could be due to this silent deficiency. Why the D3-K2-Magnesium trio works best together Together, Vitamin D3, K2, and magnesium form a protective triangle: D3 increases calcium absorption. K2 ensures calcium reaches the right places. Magnesium activates D3 and supports many body functions. Relying on D3 alone without checking on the other two can lead to imbalances and possibly missed health benefits. That's why combining all three, either through food or supplementation, makes all the difference. Natural sources that deserve a spot on the plate Good health can often begin at the dining table: For Vitamin D3: fatty fish, egg yolks, and fortified dairy. For Vitamin K2: aged cheese, butter, eggs, and fermented foods. For Magnesium: pumpkin seeds, almonds, spinach, and dark leafy greens. Even with the best diet, sunshine still plays a role. Midday sunlight for 10–20 minutes, a few times a week, helps the skin naturally produce D3. However, darker skin tones, high pollution, sunscreen use, and limited outdoor time can all reduce the body's ability to make enough. When food and sunlight aren't enough? Sometimes, lifestyle, geography, or health conditions make it hard to meet the body's needs naturally. In such cases, supplements that combine D3 and K2, along with separate magnesium support, might offer a practical solution. But quality matters. Not all supplements are made equal, and blindly taking high doses isn't always safe. Blood levels, lifestyle, and existing health conditions must all be considered. That's where guidance from a healthcare provider becomes invaluable. [Disclaimer: This article is for informational purposes only and should not be taken as medical advice. Always consult a qualified healthcare provider before making changes to diet, lifestyle, or supplements-especially when dealing with nutrient deficiencies or chronic health concerns.]
Indian Express
23-07-2025
- Health
- Indian Express
42-year-old had severe vitamin B12, Vitamin D deficiency despite diabetes medication: What caused it?
A 42-year-old man, with uncontrolled type 2 diabetes, came to us complaining of persistent fatigue, tingling in his hands and feet and trouble walking. This meant that his blood sugar had begun to damage his nerves. Predictably his HbA1c count (average blood sugar of three months) was 9.2 per cent (poorly controlled diabetes). But what surprised me was his vitamin counts: Vitamin B12: 123 pg/mL (severely deficient), Vitamin D3: 8 ng/mL (deficient) and magnesium: 1.5 mg/dL (low). So what was he doing wrong? The man had been taking Metformin for years without B12 supplementation. His diet lacked dairy and fruits due to misconceptions about managing blood sugar. After starting vitamin B12 injections and vitamin D supplementation, along with improved diets and diabetes control, his symptoms of neuropathy significantly improved over four months. This case underlines the importance of looking beyond just blood sugar numbers as vitamin deficiencies can mimic or aggravate diabetic complications. Beyond its direct effects on glucose metabolism, diabetes can also interfere with nutrient absorption, leading to several micronutrient deficiencies. Over time, these deficiencies can worsen diabetic complications such as neuropathy, poor wound healing and cardiovascular issues. Why do people with diabetes develop vitamin deficiencies? This is because of increased urinary losses. High blood sugar levels lead to a condition called osmotic diuresis, where the kidneys excrete more water and, along with it, water-soluble vitamins such as Vitamin B1 (thiamine), Vitamin B12, and Vitamin C. This effect is more pronounced in poorly controlled diabetes. Diabetes can cause gastroparesis, or delayed stomach emptying, which affects digestion and absorption of nutrients. Long-term use of Metformin, a common diabetes medication, is also known to interfere with Vitamin B12 absorption in the intestines. Chronic low-grade inflammation in diabetic patients increases the body's need for antioxidants like Vitamin C, Vitamin E and selenium. However, these nutrients are often depleted faster than they can be replenished. Type 2 diabetes is commonly associated with obesity and fatty liver, both of which impair fat metabolism. This affects the absorption of fat-soluble vitamins like A, D, E, and K. Dietary restrictions or poor diet People with diabetes often limit their food choices, sometimes avoiding fruits or certain carbohydrates due to fear of sugar spikes. This can unintentionally lead to insufficient intake of essential vitamins and minerals. Most common deficiencies Vitamin D deficiency is common as it is linked with insulin resistance and immune dysfunction. Vitamin B12 deficiency is common, especially those on Metformin, and can cause fatigue, memory loss, and worsening neuropathy. Thiamine (Vitamin B1) deficiency can lead to worsening diabetic neuropathy and cardiac issues. Magnesium is an important co-factor for insulin signalling. But this is often lost through urine in diabetics. What can patients and caregivers do? Do not miss your routine screening, especially for B12 and Vitamin D in long-term diabetes patients or those on Metformin. Include nutrient-rich foods like green leafy vegetables, low-sugar fruits, dairy, nuts, and seeds. Under the supervision of a healthcare provider, appropriate supplementation can prevent long-term complications. Also, periodic assessment of the side effects of diabetic medications is essential. Diabetes management is not just about sugar — it's about complete nutritional care. (Dr Chaturvedi is senior endocrinologist, Apollo Hospitals, New Delhi)
Time of India
21-07-2025
- Health
- Time of India
Side effects of Vitamin D shots and why no one talks about its link with blocked arteries
Vitamin D is known as "sunshine vitamin", and serves two essential purposes for human health: bone development and immune system support. However, even in a tropical country like India, Vitamin D deficiency is extremely common, due to factors like poor diet, limited sun exposure, and remaining indoors. While there are pills for the deficiency, doctors sometimes administer Vitamin D injections to patients with extremely low levels, since these enter the bloodstream directly. However, do you know that these injections can have serious side effects, including blocked arteries? Let's take a look.. What Are Vitamin D Shots Doctors administer Vitamin D3 shots to patients who need strong vitamin D therapy, because their levels are critically low, or their bodies fail to absorb the vitamin through food or pills. The high dose of Vitamin D3 injected into your muscles delivers the treatment directly to your bloodstream, which accelerates deficiency correction. Common Side Effects of Vitamin D Shots Most individuals experience no issues with vitamin D injections, yet potential side effects exist: The most common side effect is pain or swelling that develops at the injection site which resolves itself within several hours or days. The area may become bruised when people receive multiple injections, which results in discomfort at the injection site. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Earn Upto 5k Daily By This Method of Intraday Trading TradeWise Learn More Undo Some people might experience nausea together with vomiting, when vitamin D accumulation exceeds safe levels. When people experience excessive vitamin D levels in their bodies, they often develop vomiting and stomach nausea. The symptoms of headache and dizziness tend to be mild, yet they can become bothersome if they persist for a longer period. Some people develop constipation, while others experience a dry metallic taste in their mouth. Excessive vitamin D consumption leads to decreased hunger and subsequent weight reduction, and muscle weakness in the body. A few individuals experience mood variations and mental confusion, together with cognitive difficulties. Rare instances of high doses may result in heart rhythm alterations, which produce fast or slow or irregular heartbeats. When vitamin D levels become excessive in the blood, it leads to both increased thirst and more frequent urination. Excessive consumption of vitamin D over time can create dangerous calcium levels, which damage the kidneys and produce kidney stones. The Severe Health Risks of Vitamin D Toxicity People who receive frequent or large vitamin D shots face a higher risk of developing vitamin D toxicity, because their levels become excessively high. The medical condition known as vitamin D toxicity or "hypervitaminosis D" develops when the body receives excessive amounts of this vitamin. The following signs appear during this condition: Confusion or disorientation Extreme tiredness High calcium in the blood (hypercalcemia): causes confusion, vomiting, kidney stones, heart issues Severe dehydration Why No One Talks About Blocked Arteries and Vitamin D Your body uses vitamin D to absorb calcium for bone health maintenance. Elevated vitamin D levels create a situation where calcium starts accumulating beyond bones, and enters other body regions such as blood vessels. Arterial Calcification: How Vitamin D May Be Linked The medical term arterial calcification describes the process of artery blockage through calcium accumulation. The process of arterial stiffening through atherosclerosis occurs when arteries become more prone to blockages. Scientific research shows that taking excessive doses of vitamin D creates conditions where calcium forms deposits in arteries, instead of bones leading to future heart disease development. Research: What Does the Science Say Observational studies demonstrate that very low vitamin D levels are connected with higher heart risks, even though research on vitamin D supplements and injections for heart disease prevention remains inconclusive. Studies of high vitamin D dosages in animals sometimes show arterial calcification, but the results do not consistently apply to human subjects. Research demonstrates that vitamin D toxicity from excessive doses or prolonged use, results in elevated blood calcium levels which can cause arterial calcification and potentially lead to blocked arteries. Research indicates that Vitamin D deficiency poses risks to the heart, but high or excessive intake in people who do not require it, does not offer clear cardiovascular benefits and could potentially cause harm. Are Vitamin D Shots Safe for Your Arteries The majority of people experience no harm from receiving a single shot or undergoing short-term medical treatment under doctor supervision. But: People who have heart disease together with a history of kidney stones and elevated blood calcium levels, require extra attention during treatment. The risk increases when patients receive prolonged or high-dose injections without blood testing. Sources WebMD The National Institutes of Health (NIH) Cleveland Clinic and Mayo Clinic MedlinePlus
Evening Standard
16-07-2025
- Health
- Evening Standard
The best subscription services to streamline your life
All-in-one multivitamins are so last century. These personalised vitamin stacks are the latest, hi-tech way to get all the nutrients you need, without needlessly gulping down the ones you don't. If you're looking for one tablet to suit all ills, these 3D-printed stacks won't fit the bill but they are perfect if you want a supplement designed for your unique needs, according to your diet, deficiencies and individual goals. Before ordering, you fill in an easy quiz to work out exactly what will be in your stack. This covers how well you're sleeping, how much exercise you do, how often you travel abroad, whether you wear glasses and if you suffer from a range of complaints including depression, IBS and low libido. You'll also select your top two priorities, whether that's to lose weight, manage stress better or delay ageing. A box of personalised vitamin stacks arrives in the post soon after and will be delivered every 28 days if you take out a subscription. Each one is vegan and sugar-free and includes a combination of seven nutrients, selected to best suit your needs. Ours included the unusual Scutell-Up to help relieve stress and regulate sleep, vegan Vitamin D3 to boost natural immunity and support muscle function and Vitamin B12 (Cyanocobalamin) to increase energy levels.
