Latest news with #WesternUniversity
Malaysian Reserve
8 hours ago
- Health
- Malaysian Reserve
Creyos Featured in Alzheimer's Research at AAIC 2025
Findings from Western University, QIMR Berghofer, and Rotman Research Institute underscore the power of Creyos in detecting early risk, validating digital testing, and uncovering markers of cognitive resilience. Used in over 400 peer-reviewed studies, Creyos continues to power cutting-edge brain health research around the world. TORONTO, July 29, 2025 /PRNewswire/ — Creyos, the digital platform trusted by clinicians and researchers to assess brain health with precision and ease, was featured in three independent research presentations at the 2025 Alzheimer's Association International Conference (AAIC). The studies demonstrate how Creyos is helping researchers advance the science of early detection, understand risk, and explore what protects cognitive health as we age. Built on more than 30 years of neuroscience research and validated in over 400 peer-reviewed studies, Creyos enables fast, reliable measurement of key cognitive domains—including memory, attention, reasoning, and executive function. For decades, leading research institutions have leveraged the platform to explore large-scale questions that demand high-quality, scientifically reliable data, with three notable studies chosen for presentation at AAIC this year. 'Creyos wasn't born in a boardroom—it came out of necessity in the lab,' said Adrian Owen, Professor of Cognitive Neuroscience and Imaging at the University of Western Ontario, Chief Scientific Officer at Creyos, and co-author of one of the featured AAIC posters. 'It started as a way to solve a problem I faced in my own research—how to measure cognition in a way that's both rigorous and scalable. Since then, it's been used by hundreds of colleagues around the world, contributing to a growing body of work aimed at understanding cognitive health. It's rewarding to see the role it's playing in advancing research across the field.' Highlights from AAIC presentations included: 1. Early Screening Through Digital TasksWestern University – Adrian Owen, PhDUsing data from over 4,000 older adults, researchers applied machine learning to identify the two most predictive Creyos tasks for detecting age-related cognitive impairment. A screener using attention and working memory tasks matched mild cognitive impairment rates in a validation sample of over 9,000 adults, and correctly identified 100% of 14 participants with a clinical Alzheimer's disease diagnosis. The study positions Creyos as a powerful digital alternative to traditional dementia screening tools. 2. Genetics, Risk, and Online Testing in the PISA StudyQIMR Berghofer – Michelle Lupton, PhDThis study, conducted within the Prospective Imaging Study of Aging (PISA)—one of the world's largest cohorts focused on early Alzheimer's detection—validated the use of the Creyos platform for online cognitive testing in adults aged 42–75. Researchers compared self-administered Creyos assessments with traditional in-person testing and MRI-derived brain morphology measures. Findings showed strong alignment between online and in-person results, including associations with Alzheimer's-related brain changes and genetic risk. The study underscores the potential of online cognitive testing as a scalable, cost-effective tool for early detection and large-scale research in Alzheimer's disease. 3. Cognitive Resilience in Aging AdultsRotman Research Institute – Brian Levine, PhDWhy do some people maintain cognitive function despite age-related pathology or trauma? This study used Creyos to assess over 3,300 individuals across three cohorts. The Grammatical Reasoning task emerged as a potential marker of resilience—strong performance was associated with less excessive reliance on episodic memory strategies and greater resilience following PTSD. These insights point to reasoning ability as a potential buffer against cognitive decline. These studies demonstrate that Creyos is no stranger to rigorous science. The platform's role in the research being showcased at AAIC reflects not only continued trust among the global scientific community but also growing momentum in how cognitive data can support early detection, care planning, and treatment across settings. Creyos is used by healthcare providers in primary care, neurology, and behavioral health to screen for cognitive impairment, monitor longitudinal change, and inform care decisions. With nearly 20 million assessments completed and more than 10,000 providers actively using the platform, Creyos is reshaping how brain health is measured, bridging the gap between research insights and real-world care. About Creyos Creyos, formerly known as Cambridge Brain Sciences, is a pioneering healthcare technology company dedicated to transforming how healthcare providers assess and manage patient brain health. Supporting clinicians and health systems worldwide, the Creyos platform includes objective online tasks, digital behavioral health screeners, and condition-specific assessments that deliver actionable insights, promote early intervention, and enable evidence-based clinical decisions for various cognitive and behavioral health conditions, including dementia, ADHD, depression, anxiety, and others. Backed by 30 years of research and a normative database of over 85,000 participants, the FDA-registered Creyos platform has been published in over 400 peer reviewed studies and is recognized as a scientifically-validated solution for measuring and monitoring patient brain health. For more information about Creyos visit Media Contactcreyos@
CTV News
11 hours ago
- Health
- CTV News
Knee surgery changes course of common knee problem, according to local researchers
London-based study shows that a specialized knee surgery can prevent knee replacement. CTV's Reta Ismail has more. Researchers at Western have made significant progress treating a common knee issue, allowing some to avoid knee replacement. People suffering with knee osteoarthritis, a condition which brings pain, stiffness and sometimes the need for joint replacement surgery, can undergo a surgical operation called high tibial osteotomy. 'So in the surgery, they'll take that maligned limb, so that bowed limb, and actually straighten it to shift loads away from the most damaged compartment of the knee,' said Dr. Trevor Birmingham, professor and Canada research chair in musculoskeletal rehabilitation in Western's faculty of health sciences. The study is led by researchers at Western University and the Fowler Kennedy Sport Medicine Clinic. A two-year clinical trial followed 145 patients and compared those who had HTO and non-surgical therapy with those who only had therapy. The results showed that HTO slowed joint damage, reduced pain and improved movement. This is the first real evidence that a treatment can cand the course of osteoarthritis. The surgery is less common than joint replacement, but the researchers believe it needs more attention to help people in their 50s with specific alignment issues. - With files from CTV's Reta Ismail
Yahoo
a day ago
- Health
- Yahoo
Creyos Featured in Alzheimer's Research at AAIC 2025
Findings from Western University, QIMR Berghofer, and Rotman Research Institute underscore the power of Creyos in detecting early risk, validating digital testing, and uncovering markers of cognitive resilience. Used in over 400 peer-reviewed studies, Creyos continues to power cutting-edge brain health research around the world. TORONTO, July 29, 2025 /PRNewswire/ -- Creyos, the digital platform trusted by clinicians and researchers to assess brain health with precision and ease, was featured in three independent research presentations at the 2025 Alzheimer's Association International Conference (AAIC). The studies demonstrate how Creyos is helping researchers advance the science of early detection, understand risk, and explore what protects cognitive health as we age. Built on more than 30 years of neuroscience research and validated in over 400 peer-reviewed studies, Creyos enables fast, reliable measurement of key cognitive domains—including memory, attention, reasoning, and executive function. For decades, leading research institutions have leveraged the platform to explore large-scale questions that demand high-quality, scientifically reliable data, with three notable studies chosen for presentation at AAIC this year. "Creyos wasn't born in a boardroom—it came out of necessity in the lab," said Adrian Owen, Professor of Cognitive Neuroscience and Imaging at the University of Western Ontario, Chief Scientific Officer at Creyos, and co-author of one of the featured AAIC posters. "It started as a way to solve a problem I faced in my own research—how to measure cognition in a way that's both rigorous and scalable. Since then, it's been used by hundreds of colleagues around the world, contributing to a growing body of work aimed at understanding cognitive health. It's rewarding to see the role it's playing in advancing research across the field." Highlights from AAIC presentations included: 1. Early Screening Through Digital TasksWestern University – Adrian Owen, PhDUsing data from over 4,000 older adults, researchers applied machine learning to identify the two most predictive Creyos tasks for detecting age-related cognitive impairment. A screener using attention and working memory tasks matched mild cognitive impairment rates in a validation sample of over 9,000 adults, and correctly identified 100% of 14 participants with a clinical Alzheimer's disease diagnosis. The study positions Creyos as a powerful digital alternative to traditional dementia screening tools. 2. Genetics, Risk, and Online Testing in the PISA StudyQIMR Berghofer – Michelle Lupton, PhDThis study, conducted within the Prospective Imaging Study of Aging (PISA)—one of the world's largest cohorts focused on early Alzheimer's detection—validated the use of the Creyos platform for online cognitive testing in adults aged 42–75. Researchers compared self-administered Creyos assessments with traditional in-person testing and MRI-derived brain morphology measures. Findings showed strong alignment between online and in-person results, including associations with Alzheimer's-related brain changes and genetic risk. The study underscores the potential of online cognitive testing as a scalable, cost-effective tool for early detection and large-scale research in Alzheimer's disease. 3. Cognitive Resilience in Aging AdultsRotman Research Institute – Brian Levine, PhDWhy do some people maintain cognitive function despite age-related pathology or trauma? This study used Creyos to assess over 3,300 individuals across three cohorts. The Grammatical Reasoning task emerged as a potential marker of resilience—strong performance was associated with less excessive reliance on episodic memory strategies and greater resilience following PTSD. These insights point to reasoning ability as a potential buffer against cognitive decline. These studies demonstrate that Creyos is no stranger to rigorous science. The platform's role in the research being showcased at AAIC reflects not only continued trust among the global scientific community but also growing momentum in how cognitive data can support early detection, care planning, and treatment across settings. Creyos is used by healthcare providers in primary care, neurology, and behavioral health to screen for cognitive impairment, monitor longitudinal change, and inform care decisions. With nearly 20 million assessments completed and more than 10,000 providers actively using the platform, Creyos is reshaping how brain health is measured, bridging the gap between research insights and real-world care. About Creyos Creyos, formerly known as Cambridge Brain Sciences, is a pioneering healthcare technology company dedicated to transforming how healthcare providers assess and manage patient brain health. Supporting clinicians and health systems worldwide, the Creyos platform includes objective online tasks, digital behavioral health screeners, and condition-specific assessments that deliver actionable insights, promote early intervention, and enable evidence-based clinical decisions for various cognitive and behavioral health conditions, including dementia, ADHD, depression, anxiety, and others. Backed by 30 years of research and a normative database of over 85,000 participants, the FDA-registered Creyos platform has been published in over 400 peer reviewed studies and is recognized as a scientifically-validated solution for measuring and monitoring patient brain health. For more information about Creyos visit Media Contactcreyos@ View original content to download multimedia: SOURCE Creyos Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
CBC
2 days ago
- Climate
- CBC
Saturday storms produced three tornadoes near Goderich, tornado researchers confirm
3 eyewitness videos show storm, suspected tornado in southwestern Ontario 1 day ago Duration 1:29 A strong supercell thunderstorm that crossed parts of southwestern Ontario on Saturday produced three separate tornadoes in the span of an hour, researchers with Western University's Northern Tornadoes Project confirmed Monday. All three tornadoes spawned between 6:30 p.m. and 7:30 p.m. on Saturday near Goderich as the storm system came ashore from Lake Huron. The first tornado occurred on the lake as a waterspout, about 14 kilometres northwest of Bayfield, according to coordinates provided by Northern Tornadoes Project (NTP). "Then it weakened a bit, and once it got on shore, it started producing a tornado again at Porter's Hill ... then it intensified again and produced another tornado further inland near Harlock," said David Sills, NTP's director. The three tornadoes produced minor damage on land, and have been classified as EF-0 in strength, the weakest rating on the enhanced Fujita scale. No injuries have been reported, Sills said. NTP conducted a ground and drone survey of the area on Sunday to document damage and to chart the paths of the two land tornadoes. "The one bit of structural damage we know about from the tornado near Porter's Hill was a structure that had its roof peeled back," along Sharpes Creek Line, Sills said. Damage to a coverall building and to trees was also reported. That twister had wind speeds of at least 124 km/h, and travelled 6.24 kilometres with a maximum path width of 190 metres, he said. "The other tornado that hit Harlock was really impressive visually, but only produced weak damage — basically 90 km/h, a few tree branches broken," he said. It travelled nearly 4.7 kilometres with a maximum path width of 330 metres. CBC News spoke with several residents on Sunday who recalled there being a calm before the storm's quick arrival. "We sat down to have dinner, and all of a sudden my mom was like, 'You need to get to your safe place,'" said Deobrah Caira who lives near Blyth in the area where the third tornado touched down. "I said, 'It's all clear and sunny outside.' Sure enough, I looked outside, and I saw this cloud formation rotating, coming toward us." A short time later, the family took cover in the home's centre hallway as the tornado ripped by their property. "The doors were shaking on their hinges. The whole house was shaking," Caira said. The passing tornado dissipated through a field behind the family's property, but not before it damaged a 150-year-old tree and tossed Caira's roadside vegetable stand down the driveway. "There was a bit of confusion ... because there was a large marine tornado warning issued as the tornado over the lake was happening. I think quite a few people on shore got that warning," Sills said. "But as the tornado moved onshore, there didn't appear to be a tornado warning issued then. When it came on shore, I don't think there was any warning or watch in effect, at that point." The three tornadoes followed an EF-1 rated downburst that occurred in Mitchell on Thursday which damaged several barns, power pole, trees, and crops.
CTV News
2 days ago
- Climate
- CTV News
‘Downburst' confirmed near Mitchell
Ground photo of the worst damage point with the roof removed from a drive shed - winds assessed at 150 km/hr. (Source: Northern Tornadoes Project) A storm that ripped through Mitchell on July 24 has been categorized as a downburst. According to the Northern Tornadoes Project out of Western University, damage to several barns, power poles, trees and crops was reported in after a storm passed through — no injuries were reported. Damage assessed an EF1 downburst, with an estimated maximum wind speed of 150 km/h. Intermittent damage was found over an area approximately 13.4 km long and up to 8.6 km wide.
