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What a grieving mother's story shows us about the fentanyl crisis in Indianapolis

What a grieving mother's story shows us about the fentanyl crisis in Indianapolis

Yahoo3 days ago

The piercing chirps and fluttering of parakeets echo through the single-family home in east Indianapolis.
Diane Holt, 73, cares for Pretty Boy and Pretty Girl like she would children, keeping their long, white cage just feet from her bed ("They're my pride and joy," she says).
They've been her only solace in the three tormented years since the death of her son, Gregory, on Feb. 15, 2022.
Greg's death was among thousands in Marion County and her story gives a snapshot into the lasting effects of the ongoing fentanyl crisis.
From Holt's granddaughter's phone call asking why police cars and an ambulance were parked outside Greg's house. The officer informing her Greg died from an overdose. And the dried tears on her only son's cheeks as he laid wrapped in the white body bag.
He still had years left in his life to cook, travel or fish – his favorite activities, she said. He appeared sober when she saw him at Christmas months earlier.
Instead, Holt watched her son become entombed at 48 years old. He left behind four children.
Losing a child so suddenly has made Holt a recluse. She copes with the grief by sleeping and her body language shows the emotional toll: Her shoulders hunch over her thin frame when she sits. Her eyes rarely look up from the ground. Her voice is barely audible.
Murder is what happened to her son, she'll say in her soft voice. She wants the person who supplied him the deadly cocktail of fentanyl and methamphetamine to land behind bars before she dies. She's asked the police, prosecutor's office and local media for help. She never gets answers − at least the one she wants.
'Justice is what I need,' she says. 'Greg had a right to live.'
Holt's story mirrors the experience of thousands of families across Indianapolis.
Drugs killed more people in the city in the past three years than homicides and car crashes combined −more than 2,000 people, to be exact. But these deaths rarely break through the crowd of daily headlines splashed with the latest shootings and violent crime.
The main culprit behind these deaths is fentanyl, a powerful opioid being laced in street drugs. In many cases, the user doesn't know the highly lethal drug is in their supply.
Fentanyl is hidden in many ways. It's being mixed into counterfeit pills disguised to look like prescription Xanax or Adderall. It's being added to cocaine, heroin and methamphetamine. The goal each time is to give a stronger high to the more hardened addict, but also ensnare the casual user. But in many cases, people die from the potent drug.
The introduction of fentanyl in the streets has created a crisis that federal investigators say is the worst they've seen in decades – far worse than the crack cocaine epidemic that gripped the nation for more than two decades.
As one deputy coroner explained: Crack cocaine created a generation of addicts and a crime wave. Fentanyl, on the other hand, is 'just death."
Holt doesn't believe her son intentionally took fentanyl. Greg's habit mostly involved a rotation of heroin, methamphetamine and cocaine. The only hint lies in his autopsy report, where the people who were with Greg in his final moments told the coroner's office they had taken methamphetamine earlier that morning − no mention of fentanyl. The report refers to his death as an "accident."
In her waiting, Holt has seen families like hers on the evening TV news rejoicing about an arrest in their relative's overdose. In those moments, the sadness washes over her again. She wants the same. But when her family has asked police whether the bystanders to Greg's death could be prosecuted, they're told the harsh reality: Jailing drug dealers who cause an overdose are among the hardest cases to prove in court.
'The coroner's office must have determined there was not enough to say it was a murder,' an Indianapolis police captain told the family in an email. 'I'm sorry that you're having to go through this.'
Law enforcement officials often say overdose investigations are some of the most complicated cases to bring an arrest and secure a conviction. For an overdose case to stand a chance, investigators must tie a person's death to the dealer who gave them the substance.
A person may also have multiple drugs in their system, each from a different dealer. Pinpointing the drug that caused a person to overdose and die, then determining where the drugs came from, can quickly become like finding a needle in a haystack.
Indiana's law targeting drug dealers is also relatively new. Police across the state are navigating how to secure an arrest in the complex and often lengthy investigations.
On a sunny March morning in 2023, Holt and her family huddled near Greg's tomb deep in the grounds of Washington East Park Cemetery.
His remains lie in the top row of the mausoleum, forcing an observer to crane their neck to see. Holt rests on a bench below, her hands tucked in the pocket of her oversized sweatshirt that swallows up her small frame.
'I hadn't heard of it until after he died,' she said, referring to fentanyl.
'I have,' Holt's daughter, Bennie, responded. A distant relative of her boyfriend died from a fatal dose just weeks earlier.
'That really opened my eyes,' she said.
The deadly traces of fentanyl found during Greg's toxicology exam leads the family to refer to the drugs that ended his life as a 'kill shot.'
It's part of what makes his death particularly cruel, says Greg's sister, Michele Alarcon. If her brother had intentionally taken the fentanyl-laced mix, she'd have more peace, she says. Instead, the family is plagued with the visions and sounds of him overdosing.
'I hope when they close their eyes at night, they hear that gurgling in their head,' Bennie chimes in, referring to the bystanders to Greg's death.
Holt nods her head, her eyes still looking to the ground.
'I can't help but think his death has been treated like a folding of the page and moving on,' she said. 'But that just hasn't been how I felt.'
In the years IndyStar has followed Holt, much of the answers about her son's overdose death remain. Who gave him the drugs? Why hasn't anyone been arrested? What evidence was left behind?
But much has changed around her. In Indiana, attitudes about addiction are evolving. On April 10, 2025, Gov. Mike Braun signed a bill decriminalizing test strips that detect traces of fentanyl - something users have long feared carrying under threat of prosecution. The bill will take effect on July 1, 2025.
Federal dollars left over from a settlement against opioid makers are starting to trickle down into programs combating addiction. Fatal overdoses continue to decline after years of record deaths. Experts credit the drop to the multiple fronts assigned to tackle the issue, including wider access to drug treatment programs and access to naloxone, the opioid reversal drug sold under the brand name Narcan.
In Marion County, Prosecutor Ryan Mears announced his intent to hold more dealers accountable as they make strides in learning the new law. In the first few years of the law being on the books, Indianapolis police only made two arrests under the dealing resulting in death law. Since then, police across the Indianapolis metro have locked up more than 20 people in fatal overdoses. At least nine have resulted in convictions.
But even as the city has made strides in lowering fentanyl overdoses, another drug has come onto the scene. Xylazine, an animal tranquilizer, has compounded the problem by increasing the risk of drug poisoning when used with fentanyl.
And the drop in overdoses, while successful, has only made a dent in fatal drug poisonings. In 2024, 506 people died in Marion County still died from suspected drug overdose.
Holt, in many ways, feels like she's withered away, too, since Greg's death.
Some days, caring for her parakeets is the only flicker of joy in the day. They make her feel needed, something she's longed for since her children reached adulthood.
So she clings to her birds, and the prospect she may get answers about the moments before Greg died.
'I'm not real religious,' she said. 'But I have hope.'
Contact reporter Sarah Nelson at sarah.nelson@indystar.com
This article originally appeared on Indianapolis Star: What a grieving mother's story tells us about Indianapolis' fentanyl crisis

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24 arrested in major Central Jersey drug bust, prosecutor announces
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Eating this popular fruit daily may support postmenopausal heart and metabolic health
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Eating this popular fruit daily may support postmenopausal heart and metabolic health

Eating fresh mango every day may help to boost women's postmenopausal heart and metabolic health, researchers said Tuesday. They found that eating about 1.5 cups of the sweet fruit a day for two weeks significantly reduced blood pressure and cholesterol among postmenopausal women living with obesity. Both blood pressure and cholesterol are key indicators of heart health. 'Risk factors like high blood pressure and unhealthy cholesterol are key contributors to cardiovascular disease, but a nutrient-rich diet that includes fresh fruit, like mango, has long been shown to help reduce those risks,' Dr. Roberta Holt, an associate researcher at UC Davis, said in a statement. 'This study shows that even short-term changes — like eating fresh mangos daily — can make a measurable impact on chronic disease risk in certain populations.' Holt was a co-author of the research which was published Tuesday in the Journal of the American Nutrition Association. The study was supported through an unrestricted grant from the National Mango Board, although the board had no influence over the study. To reach these conclusions, they examined the health of 24 women between the ages of 50 to 70 years old who were overweight or obese. Before the study period, the authors instructed them to refrain from eating mangos. Over two weeks, the researchers collected baseline measurements, measurements when consumption began during a second visit to their lab, and then more measurements at the third visit. The women ate mangos in the mornings and the evenings. Two hours after consumption, their resting blood pressure dropped and there was a reduction in average arterial pressure. After consuming mangos every day for two weeks, their total cholesterol was slashed by nearly 13 points and their bad cholesterol dropped by the same amount. A smaller follow-up with just six participants from the initial study examined insulin and sugar levels after eating the same amount of mango with 83 grams of white bread. The researchers found the women's blood sugar levels rose significantly less after eating mango than after eating white bread. Insulin levels also responded more favorably to mango. Although mangos are high in natural sugar compared to other fruits, they also provide crucial vitamins and other nutrients. Additional research is needed to determine the effects of mango consumption of heart and metabolic health, but the benefits could aid the 1.3 million U.S. women undergoing menopause: a period when the risk of heart disease rises significantly. Women spend up to 40 percent of their lives in this life stage, and nearly half of American women are affected by cardiovascular disease. 'Post-menopausal women face distinct metabolic changes that can impact their risk of developing cardiovascular disease,' said Holt. 'These findings help to identify targeted dietary strategies, like eating fresh mangos daily, to aid this at-risk population and support cardiovascular wellness and potential reductions in chronic disease risk.'

When to Choose Strattera Over Adderall
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When to Choose Strattera Over Adderall

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While some patients respond better to one, others may experience fewer adverse effects or more rapid relief with the alternative. Consulting a healthcare provider is essential to tailor the choice to individual needs and medical history. Strattera and Adderall are both approved by the FDA for treating ADHD but function in very different ways. Adderall is a stimulant composed of amphetamine salts that work by increasing the levels of dopamine and norepinephrine in the brain. This results in improved attention, reduced impulsivity, and greater overall concentration. On the other hand, Strattera is a selective norepinephrine reuptake inhibitor (NRI), which means it primarily boosts norepinephrine without significantly impacting dopamine levels. Unlike Adderall, Strattera is not a controlled substance and carries a much lower risk of abuse. One of the primary reasons to choose Strattera over Adderall is when there's a concern about substance misuse or a history of addiction. Adderall is a Schedule II controlled substance due to its high potential for abuse and dependency. For individuals with a history of substance use disorder, Adderall may pose a serious risk. Strattera, being non-stimulant and non-addictive, offers a safer alternative. It allows for effective ADHD management without the risk of reinforcing addictive behaviors, making it particularly useful in populations vulnerable to stimulant misuse. Many individuals with ADHD also suffer from comorbid mental health conditions like anxiety or depression. In such cases, Strattera may be a better option than Adderall. Stimulants like Adderall can exacerbate anxiety symptoms in some patients, leading to increased restlessness, jitteriness, or panic attacks. Strattera, on the other hand, has shown some efficacy in improving symptoms of anxiety and may also provide mild antidepressant effects due to its norepinephrine-enhancing properties. Choosing Strattera can help manage both ADHD and accompanying mood or anxiety disorders without worsening either condition. Adderall, especially the immediate-release version, has a relatively short duration of action, requiring multiple doses throughout the day. Even the extended-release versions may wear off by late afternoon or evening. In contrast, Strattera is taken once daily and offers 24-hour symptom coverage. This can be particularly advantageous for individuals who need consistent control over their ADHD symptoms throughout the day and into the evening. Students, working professionals, or parents managing multiple responsibilities might find this steady effect preferable to the peaks and troughs associated with stimulant medications. While stimulants are effective for many people, they also come with a host of potential side effects, including insomnia, appetite suppression, irritability, increased heart rate, and elevated blood pressure. For some individuals, these side effects can be intolerable or even dangerous, particularly if they have underlying cardiovascular issues. Strattera generally has a milder side effect profile and is not associated with the same degree of appetite suppression or cardiovascular stimulation. Although it has its own set of side effects, such as nausea or fatigue, these are often more manageable and tend to lessen over time. In some clinical scenarios, a non-stimulant medication like Strattera is the preferred first-line treatment. For example, in younger children (especially those under six years of age), stimulants may not be recommended due to potential side effects and lack of data on long-term safety. Pediatricians may opt for Strattera as a gentler initial approach. Additionally, parents who are concerned about the stigma or potential long-term effects of stimulant use may feel more comfortable starting their child on a non-stimulant option. Stimulants such as Adderall can interfere with sleep, especially if taken later in the day. Sleep disturbances are a common complaint among stimulant users and can contribute to irritability, mood swings, and worsening of ADHD symptoms. Strattera is less likely to cause sleep disruption and may even help improve sleep quality for some patients. For individuals who already struggle with insomnia or erratic sleep patterns, Strattera may be the better treatment choice. One of the key differences between Adderall and Strattera is how quickly they take effect. Adderall typically produces noticeable results within hours, making it ideal for patients seeking immediate symptom relief. Strattera, however, requires several days to weeks to build up in the system and reach full therapeutic effect. For patients and clinicians willing to adopt a slower, more gradual treatment approach, this delayed onset can be worthwhile, especially given Strattera's longer-term stability and lower side effect profile. Because Adderall is a controlled substance, it comes with regulatory burdens such as limited refills, stricter prescribing rules, and potential stigma. Some patients or caregivers may prefer a treatment that does not involve these complications. Strattera, being non-controlled, can be prescribed more freely and refilled more easily. This can improve medication adherence and reduce the hassle associated with frequent doctor visits or pharmacy restrictions. In some cases, clinicians may not be completely certain whether a patient's symptoms are primarily due to ADHD or another condition such as anxiety, depression, or trauma-related disorders. 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Consulting with a knowledgeable healthcare provider is crucial in determining which medication best aligns with the patient's needs and long-term goals. TIME BUSINESS NEWS

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