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Novo Nordisk's obesity drug Wegovy debuts in Thailand

Novo Nordisk's obesity drug Wegovy debuts in Thailand

Reuters28-04-2025

BANGKOK, April 28 (Reuters) - Novo Nordisk (NOVOb.CO), opens new tab has launched its hugely popular weight-loss drug Wegovy in Thailand, an executive of the Danish drugmaker's local subsidiary said on Monday, marking the injectable drug's first entry into the Southeast Asian market.
First launched in 2021, Wegovy helped make Novo Nordisk Europe's most valuable listed company until recently, worth $615 billion at its peak.
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Wegovy is available in more than a dozen countries including the United States, Japan and China, with Thailand becoming its latest market.
"We actually received the Thai FDA approval already in 2023," said Enrico Canal Bruland, vice president and general manager of Novo's Thai subsidiary. He noted that Novo was making Wegovy available in Thailand ahead of rival Eli Lilly 's (LLY.N), opens new tab Zepbound weight loss drug.
Bruland declined to provide details on Wegovy's pricing in Thailand, which has a population of around 66 million, or Novo Nordisk's plans for expansion into other Southeast Asian markets.
Wegovy is currently available for prescription in private hospitals around the country and will be available soon in public hospitals, Bruland said.
"Over the last four years, we have invested approximately 500 million Thai baht in clinical trials in Thailand," he said.
Novo Nordisk's diabetes drug Ozempic, which contains the same active ingredient as Wegovy, is already available in Thailand.
About 42% of Thailand's adult population is considered obese, and the rate of obesity in school children surged from 5.8% to 15% within two decades, according to data from the country's health ministry.
"If we then look at the economic impact that this has, approximately 1 percent of GDP is used for health-related costs that come with obesity and productivity loss," Bruland said.
"We believe with this innovation, we can make a big difference and hopefully bend this curve."

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Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) WEIGHT loss jabs could prevent a medication taken by millions of women from working - and increase patients' risk of cancer. The British Menopause Society said the jabs could cause hormone imbalance in women taking hormone replacement therapy (HRT), particularly for those with obesity, putting them 'at increased risk of womb cancer'. 1 Women commonly take a progesterone pill along with oestrogen patches or cream Credit: Getty It follows warnings to women on weight loss medications to take effective contraception, as the jabs could render the pill less effective. That's because weight loss drugs Wegovy and Mounjaro - as well as diabetes jab Ozempic - can delay the absorption of pills taken orally, as well slowing down the passage of food through the gut. Guidance suggests women taking HRT in pill form may also be at risk. 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They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients' sugar levels are too high. Can I get them? NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics. Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure. GPs generally do not prescribe the drugs for weight loss. Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk. Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health. Are there any risks? Yes – side effects are common but most are relatively mild. Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea. Dr Sarah Jarvis, GP and clinical consultant at said: 'One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.' Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia. Evidence has so far been inconclusive about whether the injections are damaging to patients' mental health. Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines. But she also stressed that the biggest risk factor for womb cancer was obesity - meaning that on the whole, weight loss jabs can cut the risk of disease. 'These drugs reduce the risk of cancer,' Prof Mukherjee said. 'But if they are prescribed to a woman who's on oestrogen through the skin, and she might already have womb thickening because she's living with obesity, and she's not absorbing the progesterone because she's been put on a weight-loss injection, she's potentially getting loads of oestrogen on top of her thickened womb lining, and that could potentially unmask cancers that are there or drive an early cancer to a more advanced stage.' The BMS put together the guidelines after calls from GPs for advice to give to patients. Dr Janet Barter, the president of the Faculty of Sexual and Reproductive Healthcare, told The Telegraph that weight loss jabs can cause side effects such as "vomiting and severe diarrhoea in some patients'. 'Obviously this could render any medication, such as HRT tablets or oral contraception, ineffective if there hasn't been enough time for them to be fully absorbed,' she said. 'If these side-effects are occurring, then people should discuss the matter with their doctor or specialist clinician to find the combination of drugs that's right for them.' Sun Health has contacted Novo Nordisk and Eli Lilly - the makers of Wegovy and Mounjaro - for comment. It follows warnings from the Medicines and Healthcare products Agency (MHRA) that GLP-1 weight loss drugs could reduce the absorption of contraceptives, due to the fact they slow down the emptying of the stomach. The watchdog also said the jabs should not be used during pregnancy, while trying to conceive or breastfeeding, over fears they could lead to miscarriage or birth defects. The MHRA explained: 'This is because there is not enough safety data to know whether taking the medicine could cause harm to the baby.' Dr Bassel Wattar, a consultant gynaecologist and medical director of clinical trials at Anglia Ruskin University, told The Sun: 'It's not the medication itself, but the weight loss that helps regulate a woman's hormones allowing her ovaries to function properly again. 'Pregnancy is more of a happy side effect.'

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