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Taiwan Targets Blood-Bag Production as China Steps Up Pressure

Taiwan Targets Blood-Bag Production as China Steps Up Pressure

Bloomberg5 hours ago

Taiwan aims to start producing its own blood bags — a key item for saving lives on the battlefield — adding to signs President Lai Ching-te is stepping up preparations for a potential conflict with China.
The Health Ministry has been working closely with other government agencies, including the National Security Council, to enhance Taiwan's medical preparedness for emergencies, Deputy Health Minister Lin Ching-yi told Bloomberg News. Strengthening domestic production capacity for key medical supplies, including blood bags, is a part of the strategy, she said, as was ensuring that imports of medical supplies were secure.

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Clover Initiates Phase I Clinical Trial for RSV + hMPV ± PIV3 Respiratory Combination Vaccine Candidates
Clover Initiates Phase I Clinical Trial for RSV + hMPV ± PIV3 Respiratory Combination Vaccine Candidates

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Clover Initiates Phase I Clinical Trial for RSV + hMPV ± PIV3 Respiratory Combination Vaccine Candidates

-- Potential First-in-Class Respiratory Combination Vaccine Candidates SCB-1022 (RSV + hMPV) and SCB-1033 (RSV + hMPV + PIV3) Enter the Clinical Trial Stage -- SHANGHAI, June 17, 2025 /PRNewswire/ -- Clover Biopharmaceuticals, Ltd. (Clover; HKEX: 02197), a global commercial-stage biotechnology company committed to unleashing the power of innovative vaccines to save lives and improve health around the world, today announced that enrollment of the first participants has been completed in a Phase I clinical trial evaluating SCB-1022 (RSV+hMPV) and SCB-1033 (RSV+hMPV+PIV3) respiratory combination vaccine candidates based on prefusion-stabilized F (PreF)-Trimer subunit vaccine antigens utilizing Clover's Trimer-Tag vaccine technology platform. "We are pleased to announce the Phase I clinical trial initiation of our potential first-in-class combination vaccine candidates SCB-1022 (RSV+hMPV) and SCB-1033 (RSV+hMPV+PIV3), further demonstrating the differentiated value of our validated Trimer-Tag platform," said Joshua Liang, Chief Executive Officer & Board Director of Clover. "While currently approved protein-based RSV vaccines are safe & effective, critical gaps persist globally, including the inability to prevent significant respiratory disease burden caused by other viruses related to RSV such as human metapneumovirus (hMPV) and parainfluenza virus type 3 (PIV3). Thus, we look forward to the clinical trial results for our respiratory combination vaccine candidates in order to maximize our impact on public health globally." In October 2024, Clover announced Phase I results in 70 older adults (60-85 years) for Clover's non-adjuvanted RSV PreF vaccine candidate (SCB-1019) compared head-to-head to GSK's AS01E-adjuvanted RSV vaccine (AREXVY), and results indicated a potential best-in-class combined immunogenicity & tolerability profile of SCB-1019. These results supported the further development and evaluation of SCB-1019 in combination with the PreF-Trimer antigens for hMPV and PIV3, which are also utilizing the Trimer-Tag platform. The ongoing Phase I trial for Clover's combination vaccine candidates is enrolling up to 192 older adults (60-85 years), and the participants will be randomized to receive either SCB-1022 (RSV+hMPV), SCB-1033 (RSV+hMPV+PIV3) or SCB-1019 (RSV) comparator. The study will assess safety, reactogenicity and immunogenicity. About Clover Clover Biopharmaceuticals is a global commercial-stage biotechnology company committed to unleashing the power of innovative vaccines to save lives and improve health around the world. With integrated research and development, manufacturing and commercial capabilities as well as strong partnerships with organizations globally, Clover has a diverse pipeline of candidates that have the potential to meaningfully reduce the burden of vaccine-preventable diseases—and to make more diseases preventable. Clover Forward-looking Statements This press release contains certain forward-looking statements and information relating to us and our subsidiaries that are based on the beliefs of our management as well as assumptions made by and information currently available to our management. When used, the words "aim," "anticipate," "believe," "could," "estimate," "expect," "going forward," "intend," "may," "might," "ought to," "plan," "potential," "predict," "project," "seek," "should," "will," "would" and the negative of these words and other similar expressions, as they relate to us or our management, are intended to identify forward-looking statements. Forward-looking statements are based on our current expectations and assumptions regarding our business, the economy and other future conditions. We give no assurance that these expectations and assumptions will prove to have been correct. Because forward-looking statements relate to the future, they are participant to inherent uncertainties, risks and changes in circumstances that are difficult to predict. Our results may differ materially from those contemplated by the forward-looking statements. They are neither statements of historical fact nor guarantees or assurances of future performance. We caution you therefore against placing undue reliance on any of these forward-looking statements. Any forward-looking statement made by us in this document speaks only as of the date on which it is made. Factors or events that could cause our actual results to differ may emerge from time to time. View original content: SOURCE Clover Biopharma Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

When an Air India flight crashed into a medical campus, surviving doctors rushed to save lives
When an Air India flight crashed into a medical campus, surviving doctors rushed to save lives

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When an Air India flight crashed into a medical campus, surviving doctors rushed to save lives

AHMEDABAD, India — Navin Chaudhary had just begun eating his meal when a loud bang startled him. He turned back to see a massive fire taking over the dining area where he and other trainee doctors had assembled for lunch. The blaze approaching him, he rushed toward a window and jumped. From the ground, looking upward, the sight of the Air India plane's tail cone hanging from the burning building propelled Chaudhary and fellow medical students into action. 'There was fire and many were injured,' said Chaudhary. He said he felt lucky to survive but knew he had a task at hand. He rushed to the hospital's intensive care unit, where the injured, most of whom had burns, were wheeled in on stretchers. 'I felt that as a doctor I could save someone's life,' he said. 'I was safe. So I thought, whatever I can do, I should.' At least 270 died when the Air India flight crashed into the campus of a medical college in Ahmedabad shortly after takeoff on Thursday. Only one passenger among the 242 aboard survived. At least 29 others on the ground, including five medical students inside the hostel, were also killed. Many believe that the death toll would have been higher if it had not been for the intervention of the trainee doctors and students who emerged from the smouldering hostel and rushed to save their colleagues. Akshay Zala, a senior medical student, said the crash felt 'like an earthquake.' 'I could hardly see anything as thick plumes of smoke and dust engulfed everything. I was barely able to breathe,' he said. Zala rushed to safety, running through dust and smoke. He cleaned and bandaged a wound on his left leg then joined others at the medical college's trauma center to treat the injured. On Monday, the crash site teemed with excavators and workers clearing the debris. Officials inspected the building in search of clues that could enable the investigators to figure out what led to the tragedy. Barely a kilometer (less than a mile) away, trainee doctors who survived one of India's worst aviation disasters were still working to identify the victims through DNA testing. Indian authorities have so far handed over the remains of 47 victims The bodies of 92 others have also been identified through DNA matching and will be transferred to relatives soon. College dean Minakshi Parikh said that many of the doctors who pulled their colleagues out of the debris, later that day went back to their duties to save as many lives as they could. 'They did that and that spirit has continued till this moment,' Parikh said. Images of the hostel's dining area shortly after the crash showed parts of the aircraft and pieces of luggage strewn on the floor. Dining plates still containing food lay on the few dusty tables that were left intact by the impact. 'So that is human nature, isn't it? When our own people are injured, our first response is to help them,' Parikh said. 'So the doctors who managed to escape ... the first thing that they did was they went back in and dug out their colleagues who were trapped inside.' 'They might not even have survived because the rescue teams take time coming,' she added.

This puffer jacket uses light and sound to lull you to sleep anywhere
This puffer jacket uses light and sound to lull you to sleep anywhere

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time3 hours ago

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This puffer jacket uses light and sound to lull you to sleep anywhere

Often described as one of the world's most sleep-deprived nations, Japan repeatedly ranks last, or near last, in international surveys and studies on sleep duration and quality. One design firm has developed a creative solution that it believes can give real power to naps. Its 'smart' puffer jacket concept is intended to optimize short naps by providing bespoke sound and lighting based on the user's biometric data, such as heart rate and body temperature, which is gathered by a wearable ring. 'We realized that sleep is a very personal thing,' said Dai Miyata, creative art director of Konel, which developed the jacket in collaboration with the sleep technology division at NTT DX Partners, a digital consulting firm. 'You can't force someone to sleep, they have to fall asleep on their own. So, we started thinking, is there something we can create that helps people ease into sleep on their own terms?' The ZZZN sleep apparel is designed to be worn day-to-day as a normal jacket, albeit an oversized one, but users can also activate 'sleep mode' by putting up the hood when they want a snooze on their commute home. Not yet intended as a consumer product, a conceptual prototype of the invention will be on display from June 24 until July 7 at Expo 2025 Osaka, where visitors will be able to test it out for themselves. Miyata hopes that the innovation will make people 'more curious about sleep,' and spark conversations about how to approach rest better. 'It's such a familiar part of life, yet there's still so much we don't know about it,' he added. Konel began developing the jacket last year with a grant from Japan's Ministry of Economy, Trade and Industry, as part of a program to transform personal healthcare data into usable services and products. 'With Japan being one of the most sleep-deprived countries, we've been thinking about how to tackle this issue through business initiatives,' said Teppei Ogata, production manager for NTT DX Partners' sleep technology division. The company's previous efforts didn't lead to significant behavior changes, Ogata said: so instead, they decided to take a 'fun and creative' approach coming up with the playful concept of 'portable sleep.' The jacket is based on 'yogi,' a quilted kimono worn which was popular in the Edo period (1615–1868) for sleeping, particularly in winter. While yogi is often compared to pajamas, it's 'closer to something you could fall asleep in, and then just wake up and go,' said Miyata. 'It's more like a fusion of clothing and bedding.' With a deep hood for privacy, the ZZZN jacket has an inbuilt system that converts the wearer's biometric data into light and sound. It uses red light to induce sleep, while blue light is intended to suppress melatonin to wake the body up. Minyata said the light pulses at rates that mimic slow breathing patterns, to promote deeper sleep, and are accompanied by 'neuromusic' with frequencies that 'act directly on brain waves to aid sleep.' Some preliminary studies have found that music or sounds of certain frequencies could improve sleep, although more research is needed. The biometric ring continues to monitor the wearer's stress as they doze off. 'If the person's stress level significantly decreases, the same light and sound are maintained, but if their stress doesn't decrease much, the system switches to sounds that are even more effective at promoting sleep,' said Miyata. While the jacket might seem like a gimmick, it's rooted in a real problem. A study published this year found that the nation was ranked last on sleep duration out of 20 nations, with an average nightly sleep duration 94 minutes shorter than France, which topped the rankings. One analysis of the economic cost of poor sleep (measured in reduced productivity, traffic accidents from tiredness, and other accidents or injuries) found that Japan loses up to $138 billion a year, which equates to around 3% of its GDP. Lack of sleep is so widespread that some schools and offices have reportedly introduced nap breaks into the day, and it's not unusual to see people sleeping in public, known as 'inemuri.' According to the Mayo Clinic, short naps of around 20 minutes can improve alertness, mood, and memory. However, napping for longer periods can disrupt your sleep cycle, and deeper stages of sleep are harder to wake up from, causing grogginess. It's not just Japan that struggles to sleep: Singapore and South Korea also have short sleep duration, while in the US, more than 50 million people (or about 15% of the total population) struggle with sleep disorders, and one-third of adults are not getting the recommended amount of sleep. A recent study found that the optimal amount of sleep appears to vary between countries, depending on cultural norms. But while it noted that those who slept close to their 'cultural ideal sleep duration,' scored best in health metrics, it also found that within individual countries, people who slept longer were healthier Miyata emphasizes that innovations like the puffer jacket are not a substitute for a good night's rest. 'We're not saying take naps so you can get by on fewer hours of sleep, but rather that by breaking up sleep intelligently, people who only get six hours of sleep might be able to get closer to eight hours, which is a positive outcome,' he said, adding: 'This isn't about solving sleep issues just so people can work more. Rather, this is a concept model aimed at creating a culture that values sleep.' The jacket, which was initially unveiled at Milan Design Week in April, is currently a 'conceptual prototype' — so while visitors to the 'Future Life Village' at Expo 2025 Osaka will be able to try it out, it's operated manually by Miyata and his team rather than adapting to each user's biometric data. Whether the conceptual sleep tech will become commercially available is still to be seen, but Ogata believes that the 'sleep system' could be adopted by regular apparel manufacturers and integrated into existing clothing products. 'We've started efforts to create collaborative products like co-branded items aimed at establishing a new kind of sleepwear value, using this system,' he said. Ogata would also like to further personalize the jacket's responses — for example, offering different music tracks for waking up. He hopes that the jacket will help to shift the cultural perception around sleep; and perhaps give some of its early users at the expo a high-tech rest. 'It really does feel like entering a personal space. You feel completely shut off from the noise of everyday life,' he added. Additional reporting by Mai Takiguchi, CNN.

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