Duke vs Arizona prediction, picks for 2025 men's NCAA Tournament Sweet 16
Duke vs Arizona prediction, picks for 2025 men's NCAA Tournament Sweet 16 It's Duke vs Arizona in the 2025 NCAA Tournament Sweet 16. See our expert picks and predictions for the March Madness bracket, along with how to watch and game time.
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Duke, Arkansas, and Houston headline Men's Sweet 16
With the Sweet 16 upon us, USA Today Sports' Mackenzie Salmon previews a few of the top matchups we're most looking forward to.
Sports Seriously
The 2025 men's NCAA Tournament is in full swing. After starting with 68 teams, the field is down to 16. A Sweet 16, that is.
Tournament action continues with the Sweet 16 on Thursday, featuring a matchup between Duke and Arizona in the East Region.
The Duke Blue Devils earned a No. 1 seed in the 2025 March Madness bracket. They knocked off the Mount St. Mary's Mountaineers in the first round and the Baylor Bears in the Round of 32 to reach this point. Duke's opponent, the 4-seeded Arizona Wildcats, defeated the Akron Zips and the Oregon Ducks en route to this showdown in Newark, N.J.
Duke ranks as the best team in the KenPom rankings, sporting the best offense and fourth-best defense. Meanwhile, Arizona ranks 13th overall with the 12th-ranked offense and 28th-ranked defense.
Here's how our experts see Thursday's Sweet 16 clash playing out. Be sure to check out USA TODAY's complete March Madness bracket predictions to see our team's picks for every game. While you're at it, don't forget to read our tournament bold predictions and upset picks.
Duke vs. Arizona picks and predictions
It's a clean sweep. None of our experts are predicting an upset in this contest. AZ Central's Jeremy Cluff is backing Arizona to cover the 8.5-point spread while USA TODAY's Craig Meyer and Fayetteville Observer's Rodd Baxley and Duke Wire's Ryan Haley are all laying the points with Duke. Cluff and Baxley are also on the under 155.5-point total.
Duke vs. Arizona date, start time, where to watch
Game Day: Thursday, March 27, 2025
Thursday, March 27, 2025 Game Time: 9:39 p.m. ET
9:39 p.m. ET Location: Prudential Center in Newark, New Jersey
Prudential Center in Newark, New Jersey TV Channel: CBS
CBS Live Stream: Fubo - Watch Now!
Watch Duke vs. Arizona on Fubo
Duke vs. Arizona odds
Odds as of Monday, March 24 via BetMGM.
Spread: Duke -8.5 (-115)
Duke -8.5 (-115) Moneyline Favorite: Duke -425
Duke -425 Moneyline Underdog: Arizona +325
Arizona +325 Total: 153.5
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