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Associated Press
17 minutes ago
- Associated Press
AP top stories June 3
The Associated Press is an independent global news organization dedicated to factual reporting. Founded in 1846, AP today remains the most trusted source of fast, accurate, unbiased news in all formats and the essential provider of the technology and services vital to the news business. More than half the world's population sees AP journalism every day.


TechCrunch
18 minutes ago
- TechCrunch
Unity CTO Steve Collins steps down after six months
Steve Collins, the CTO of the game engine developer Unity, is stepping down, a company representative confirmed to TechCrunch. He joined Unity just six months ago after serving as CTO of King, the mobile gaming company behind Candy Crush. According to Unity, Collins made the decision to leave the company of his own accord. 'We can confirm that Steve Collins has decided to leave Unity for personal reasons,' a company representative said. 'We're grateful for his contributions. As we continue our transformation, we're confident our world-class tech team will keep driving the strategy forward.' Unity has faced much internal strife over the last few years. In fall 2023, the company announced controversial changes to its pricing model that enraged the developer community. Though some of these changes were walked back, the company's CEO John Riccitiello resigned as a result. Months later, Unity laid off 25% of its staff, amounting to 1800 jobs. Though Unity now has some distance from those events, some game developers remain distrusting of the company. Collins' departure is not necessarily related to the Unity's struggles, but another executive shakeup could prove disruptive. Techcrunch event Save now through June 4 for TechCrunch Sessions: AI Save $300 on your ticket to TC Sessions: AI—and get 50% off a second. Hear from leaders at OpenAI, Anthropic, Khosla Ventures, and more during a full day of expert insights, hands-on workshops, and high-impact networking. These low-rate deals disappear when the doors open on June 5. Exhibit at TechCrunch Sessions: AI Secure your spot at TC Sessions: AI and show 1,200+ decision-makers what you've built — without the big spend. Available through May 9 or while tables last. Berkeley, CA | REGISTER NOW


Gizmodo
20 minutes ago
- Gizmodo
Smoking Weed and Eating Edibles Share This Surprising Health Risk
A new study has found a startling link between chronic cannabis use and increased risk of cardiovascular disease—regardless of whether you smoke it or consume edibles. The finding challenges commonly held beliefs about the health impacts of tetrahydrocannabinol (THC), which many see as a relatively harmless drug—especially when ingested. The study, published Wednesday, May 28 in the journal JAMA Cardiology, found that THC smokers suffer from significantly worse artery function than non-users. They observed the same effect in edible consumers, though their arteries were not as severely affected. In either case, vascular function was reduced by roughly half compared to those who do not use cannabis, according to a statement from the University of California, San Francisco. 'Scientifically, this THC result is really interesting but boy does it screw up the public health messaging,'' co-author Matt Springer, a cardiovascular researcher at UCSF, reportedly said to lead author and UCSF physician-scientist Leila Mohammadi when he saw the data. These results add to a growing body of evidence that suggests long-term weed use can lead to cardiovascular damage and life-threatening events such as heart attacks and strokes, though experts still lack consensus on its precise impacts. A 2024 study published in the Journal of the American Heart Association found that people who consume cannabis daily had a 25% increased risk of heart attack and a 42% increased risk of stroke compared to non-users. For this new study, researchers investigated how cannabis impacts vascular function. To isolate the effects of chronic cannabis use, they recruited 55 otherwise healthy adults aged 18 to 50 who did not use any form of nicotine and were not frequently exposed to secondhand smoke. These participants were sorted into three groups: marijuana smokers, edible users, and non-users. Those in the two cannabis user groups reported taking the drug at least three times per week, either exclusively through smoking or edibles. To assess the participants' vascular function, the researchers measured dilation of the brachial artery—located in the upper arm—to determine whether it could properly expand in response to increased blood flow. To that end, they used an inflatable forearm cuff to briefly block blood flow to the artery, then used ultrasound to measure its diameter before and after inflating the cuff. Matt Springer, a cardiovascular researcher at UCSF whose lab led the study, told Live Science that his test offers a 'window into the future.' When blood vessels cannot fully dilate, he said, the risk of heart attack and other poor cardiovascular outcomes increases. Participants who did not consume cannabis showed an average vessel dilation—represented as the percent change from the baseline measurement of artery diameter—of 10.4%. This value was significantly reduced among weed smokers and edible users, who showed an average vessel dilation of 6.0% and 4.6%, respectively. For reference, average values for brachial artery dilation in healthy individuals typically range from 8.0% to 15%. In a previous study, Springer's lab found similarly reduced levels of vessel dilation among e-cigarette and cigarette smokers. To better understand how THC causes this change, the researchers ran lab tests to determine how endothelial cells—which form the linings of blood vessels and release nitric oxide to trigger dilation—responded to the participants' blood samples. These tests revealed that the blood of chronic cannabis smokers inhibited nitric oxide production in the cells, which may explain why these participants showed reduced vessel dilation. This effect was not observed in edible consumers, however, suggesting that ingestible THC may impact arterial function via an entirely separate mechanism. Figuring out what that mechanism may be will require further research. What's more, subsequent studies will need to reproduce these findings in a larger population to validate the results. Within the last several years, cannabis use among U.S. adults has reached new heights, according to the NIH's National Institute on Drug Abuse. As such, investigating the health effects of THC is more important than ever before—especially as mounting evidence challenges perceptions of weed as a harmless high.