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ZINZINO AB (PUBL.): INTERIM REPORT FIRST QUARTER 2025

ZINZINO AB (PUBL.): INTERIM REPORT FIRST QUARTER 2025

Yahoo20-05-2025

GOTHENBURG, Sweden, May 20, 2025 /PRNewswire/ --
STRONG SALES GROWTH AND INCREASED EARNINGS IN THE FIRST QUARTER
Revenues in the first quarter of 2025 amounted to SEK 723.7 (454.5) million, corresponding to 59% (15%) growth compared to the corresponding period last year. In local currencies, revenues for the first quarter increased by 60% compared to the corresponding period last year. EBITDA increased to SEK 78.8 (51.7) million and the EBITDA margin amounted to 10.9% (11.4%). During the quarter, the acquisition of Zurvita's assets with associated distributor and customer database was completed. The acquisition consolidates Zinzino's position in North America and adds further growth in the region. In addition, New Zealand was launched as an official market during the quarter. After the end of the quarter, the assets of the US/UK based direct sales company Valentus Global was acquired in order to add increased distribution power in Europe.
JANUARY-MARCH
- Total revenue amounted to SEK 723.7 (454.5) million, corresponding to a growth of 59% (15%)- Gross profit amounted to SEK 223.6 (160.9) million and the gross profit margin was 30.9% (35.4%)- EBITDA amounted to SEK 78.8 (51.7) million and the EBITDA margin was 10.9% (11.4%)- Cash flow from operating activities totalled SEK 21.1 (-1.7) million- Zinzino's Board of Directors proposes a dividend to shareholders of SEK 4.00 (3.00) per share for the financial year 2024, corresponding to a total of SEK 143.1 (102.7) million
Link to the report:https://www.zinzino.com/site/SE/sv-SE/om-oss/investerare/
For more information, please contact:Dag Bergheim Pettersen CEO Zinzino +47 (0) 932 25 700, dag@zinzino.comFredrik Nielsen CFO Zinzino +46 (0) 707 900 174, fredrik.nielsen@zinzino.com
Images for free publication:marketing@zinzino.com
Certified Adviser: DNB Carnegie Investment Bank AB
Zinzino AB (publ.) is obliged to publish this information in compliance with current EU regulations governing market abuse. The information was provided by the above contact person for publication at 10:00 CEST on 20 May 2025.
Zinzino is a global direct selling company from Scandinavia specialising in test-based, personalised supplements and scientific skincare. It is a public limited company with shares listed on Nasdaq First North Premier Growth Market. The company's scientifically proven supplements are available in more than 100 markets worldwide. Zinzino has acquired all the assets of the US health and wellness companies Zurvita and Xelliss. The company is part-owner of the Cypriot olive oil manufacturer Cleanthi Alpha-Olenic LTD and owns the Swiss biotech skincare brand HANZZ+HEIDII, as well as the Norwegian research and production units BioActive Foods AS and Faun Pharma AS. The company is headquartered in Gothenburg, Sweden, with additional offices in Europe, Asia and Australia.
View original content:https://www.prnewswire.com/news-releases/zinzino-ab-publ-interim-report-first-quarter-2025-302460666.html
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The publication of the OptiTROP-Lung03 study in the British Medical Journal marks a major milestone—not only highlighting international recognition of this study outcomes in lung cancer, but also demonstrating the global competitiveness of sac-TMT as a novel TROP2 ADC." Dr. Michael Ge, CEO of Kelun-Biotech, commented: "We are thrilled to see the OptiTROP-Lung03 study published in a top-tier journal. Currently, EGFR-TKIs and chemotherapy remain the standard of care for patients with EGFR-mutant advanced NSCLC, but the challenge of increasing efficacy with manageable tolerability. The results from OptiTROP-Lung03 highlight significant survival benefits with manageable safety profile and suggest that sac-TMT could emerge as a new standard of care for this population. We remain committed to working with our partners to establish sac-TMT as a new standard of care for this patient population and improve outcomes for lung cancer patients worldwide." Registrational Study Led by Kelun-Biotech OptiTROP-Lung03: Sac-TMT monotherapy versus docetaxel for locally advanced or metastatic EGFR-mutant NSCLC after treatment failure with EGFR-TKI and platinum-containing chemotherapy; OptiTROP-Lung04: Sac-TMT monotherapy versus pemetrexed in combination with platinum for locally advanced or metastatic non-squamous NSCLC with EGFR mutations that have failed EGFR-TKI therapy; OptiTROP-Lung05: Sac-TMT combined with pembrolizumab versus chemotherapy combined with pembrolizumab for first-line treatment of PD-L1-positive locally advanced or metastatic NSCLC; OptiTROP-Lung06: Sac-TMT combined with pembrolizumab versus chemotherapy combined with pembrolizumab for the first-line treatment of PD-L1-negative locally advanced or metastatic non-squamous NSCLC; OptiTROP-Lung07: First-line treatment of locally advanced or metastatic NSCLC with EGFR mutations by sac-TMT in combination with ositinib. Registrational Study Led by MSD NSCLC not achieving a pCR after neoadjuvant therapy followed by surgery. NSCLC expressing PD-L1 >50% pre-treated NSCLC with EGFR mutations or other genomic alterations EGFR-mutated, advanced non-squ NSCLC progressed on prior EGFR-TK metastatic sg NSCLC About sac-TMT Sac-TMT, a core product of the Company, is a novel human TROP2 ADC in which the Company has proprietary intellectual property rights, targeting advanced solid tumors such as NSCLC, BC, gastric cancer (GC), gynecological tumors, among others. Sac-TMT is developed with a novel linker to conjugate the payload, a belotecan-derivative topoisomerase I inhibitor with a drug-to-antibody-ratio (DAR) of 7.4. Sac-TMT specifically recognizes TROP2 on the surface of tumor cells by recombinant anti-TROP2 humanized monoclonal antibodies, which is then endocytosed by tumor cells and releases KL610023 intracellularly. KL610023, as a topoisomerase I inhibitor, induces DNA damage to tumor cells, which in turn leads to cell-cycle arrest and apoptosis. In addition, it also releases KL610023 in the tumor microenvironment. Given that KL610023 is membrane permeable, it can enable a bystander effect, or in other words kill adjacent tumor cells. In May 2022, the Company licensed the exclusive rights to MSD (the tradename of Merck & Co., Inc., Rahway, NJ, USA) to develop, use, manufacture and commercialize sac-TMT in all territories outside of Greater China (includes Mainland China, Hong Kong, Macao, and Taiwan). To date, two indications for sac-TMT have been approved and marketed in China for the treatment of adult patients with unresectable locally advanced or metastatic TNBC who have received at least two prior systemic therapies (at least one of them for advanced or metastatic setting) based on the OptiTROP-Breast01 study and EGFR mutation-positive locally advanced or metastatic non-squamous NSCLC following progression on EGFR-TKI therapy and platinum-based chemotherapy based on the OptiTROP-Lung03 study. Sac-TMT became the first domestic ADC with global intellectual property rights to be fully approved for marketing. It is also the world's first TROP2 ADC to be approved for marketing in a lung cancer indication. In addition, two new indication applications for sac-TMT for the treatment of adult patients with EGFR-mutant locally advanced or metastatic NSCLC who progressed after treatment with EGFR-TKI therapy and with unresectable locally advanced, metastatic hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-) BC who have received prior endocrine therapy and other systemic treatments in the advanced or metastatic setting were accepted by the National Medical Products Administration (NMPA), and were reviewed via the priority review and approval process. As of today, the Company has initiated 8 registrational clinical studies in China. MSD has initiated 14 ongoing Phase 3 global clinical studies of sac-TMT as a monotherapy or with pembrolizumab or other agents for several types of cancer. These studies are sponsored and led by MSD. About Kelun-Biotech Kelun-Biotech( a holding subsidiary of Kelun Pharmaceutical ( which focuses on the R&D, manufacturing, commercialization and global collaboration of innovative biological drugs and small molecule drugs. The company focuses on major disease areas such as solid tumors, autoimmune, inflammatory, and metabolic diseases, and in establishing a globalized drug development and industrialization platform to address the unmet medical needs in China and the rest of world. The Company is committed to becoming a leading global enterprise in the field of innovative drugs. At present, the Company has more than 30 ongoing key innovative drug projects, of which 3 projects have been approved for marketing, 1 project is in the NDA stage, and more than 10 projects are in the clinical stage. The company has established one of the world's leading proprietary ADC platforms, OptiDC™, and has 1 ADC project approved for marketing, 1 ADC project in NDA stage, and multiple ADC and novel coupled drug products in clinical or preclinical research stage. For more information, please visit Media: klbio_pr@ View original content to download multimedia: SOURCE Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

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