TikToker Anna Grace Phelan Dead at 19 After Cancer Battle
Originally appeared on E! Online
The influencer community has lost a beloved member.
TikToker Anna Grace Phelan died May 23 after a battle with brain cancer. The Jefferson, Georgia-based influencer was 19.
"It is with great sadness to announce that our beautiful daughter, Anna Grace Phelan, went home to be with her Lord and Savior Jesus Christ," read a message posted on the influencer's TikTok page. "So many of you have followed her journey through a difficult battle with cancer and bore witness to her powerful testimony of faith."
"Thank you for the countless thousands of prayers for healing and peace," the message continued. "May we all rejoice with the assurance that she is in Heaven now, and she has been healed. Let us also remember that the only path to the promised kingdom of Heaven is through salvation in Jesus Christ."
Anna is survived by her parents, William "Buddy" Phelan and Nadine Phelan, brother Harper David Phelan and other family members.
"I started to experience numbness in the left side of my face and in the right side of my leg," Anna said in a TikTok video posted last August. "We scheduled an MRI appointment of my brain, and that scan did show a lesion on my brain."
Her symptoms soon worsened. "I started losing my balance. I started having vision problems in my left eye, my numbness in my face and on my leg is still here," she continued. "My speech started to seem weird. My head's very foggy."
Anna then underwent a brain biopsy, which revealed she had a tumor. She was soon diagnosed with an inoperable, Grade 4, malignant and aggressive brain tumor called a glioblastoma.
"This is definitely the hardest news I've ever received," she said in a TikTok video in September 2024. "By all means, this is not easy. Just going to trust in the Lord and try and keep pushing forward."
More from E! Online
Duck Dynasty's Phil Robertson Dead at 79 After Alzheimer's Diagnosis
Rosie O'Donnell Reveals Weight Loss Transformation After Using Mounjaro
Bindi Irwin Shares Update on Healing Journey 2 Weeks After Emergency Surgery
Anna, who was born in Orlando, Fla., had documented her brain cancer battle on social media. Her diagnosis came in September 2024, days before she was set to start her freshman year of college, per her GoFundMe page and a month after symptoms began.
"I started to experience numbness in the left side of my face and in the right side of my leg," Anna said in a TikTok video posted last August. "We scheduled an MRI appointment of my brain, and that scan did show a lesion on my brain."
Her symptoms soon worsened. "I started losing my balance. I started having vision problems in my left eye, my numbness in my face and on my leg is still here," she continued. "My speech started to seem weird. My head's very foggy."
Anna then underwent a brain biopsy, which revealed she had a tumor. She was soon diagnosed with an inoperable, Grade 4, malignant and aggressive brain tumor called a glioblastoma.
"This is definitely the hardest news I've ever received," she said in a TikTok video in September 2024. "By all means, this is not easy. Just going to trust in the Lord and try and keep pushing forward."
In her final days, Anna spent increased time with her loved ones. A video of her hanging out with friends in a backyard was also shared to her page May 15.
One day earlier, the TikToker revealed to her followers that her brain tumor had grown and was inoperable. "Keep me in your prayers," she said in her May 14 video. "Thank you all so much."
Anna will be honored at a funeral at a church in Jefferson May 29.
For the latest breaking news updates, click here to download the E! News App
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


Health Line
an hour ago
- Health Line
Ask the Expert: Should I have Biomarker Testing – and Would it Help?
Biomarker testing in colorectal cancer can help assess inherited risk and identify characteristics that may influence the disease's growth, spread, and response to treatment. Colorectal cancer (CRC) starts in the colon or rectum of the large intestine. Your doctor may refer to it as 'colon cancer' or 'rectal cancer,' depending on where the cancer develops first, but both of these diagnoses are included under the banner of CRC. CRC is treatable, and biomarker testing is a part of precision medicine in your comprehensive treatment plan. Biomarker testing in CRC can help detect cancer in its earliest, most treatable stages. It can also provide important details about cancer after a diagnosis that influence treatment and outcomes. Dr. Smitha Krishnamurthi, a gastrointestinal oncology specialist with the Cleveland Clinic, talks with Healthline about biomarker testing and who it's recommended for. What is biomarker testing? Biomarker testing refers to testing of the colorectal cancer to find out if there are certain changes in the cancer's genes and proteins that could impact prognosis [outlook] and treatment. What are the most common biomarkers, and what do they show? Biomarkers in CRC measure a variety of different biological processes and states. Each biomarker provides important details about the cancer's growth, spread, or treatment response. DNA mismatch repair Hospital pathology labs now commonly test all initial biopsies or surgical specimens of colorectal cancer for the presence of DNA mismatch repair proteins. This is done via immunohistochemistry (IHC) staining of the slides to look for [the] expression of four mismatch repair proteins: MLH1, PMS2, MSH2, and MSH6. If one or two of these proteins are missing, then the cancer has deficient DNA mismatch repair. Microsatellite instability (MSI) This is a polymerase chain reaction (PCR) or next-generation sequencing (NGS) test [that looks] for abnormalities in microsatellite regions of the cancer DNA. The test can be done on a tumor specimen or blood (liquid biopsy). Microsatellites are short, repeated sequences of DNA. If the cancer has [atypical] DNA mismatch repair, errors will appear in microsatellite regions of DNA in the form of missing bases or extra bases added to the DNA sequence. RAS gene mutations (mutations in KRAS and NRAS genes) This testing can be performed by PCR or NGS testing of the tumor or NGS testing of blood (liquid biopsy). RAS is a very important oncogene, meaning that it is a gene that, when mutated, drives cancer cell proliferation and survival. Mutations in RAS genes are found in up to 50% of colorectal cancers. BRAF V600E gene mutation This testing can be performed by PCR or NGS testing of the tumor or NGS testing of blood (liquid biopsy). The BRAF V600E protein can also be detected by IHC. BRAF is another oncogene, so when it is mutated, it leads to cancer cell proliferation and survival. BRAF V600E mutations occur in about 8% to 10% of colorectal cancers and are more common in right-sided cancers. HER2 protein overexpression by IHC or gene amplification by NGS HER2 is another oncogene — gene amplification leads to [the] overexpression of the HER2 protein. Overexpression of HER2 leads to increased signaling via the epidermal growth factor receptor pathway, leading to cancer cell proliferation and survival. PIK3CA PIK3CA is another oncogene. Mutations in PIK3CA and a related gene, PIK3R1, lead to cancer cell proliferation and survival. Mutations in PIK3CA and PIK3R1 are typically found via NGS. PTEN PTEN is a tumor suppressor gene, [which typically] suppresses cancer growth. When the PTEN gene is mutated, the protein is not expressed, and that leads to [the] proliferation of cancer. PTEN gene mutations are typically found via NGS. Who should have biomarker testing done? All patients with colorectal cancer should have testing of their cancer for DNA mismatch repair (or microsatellite instability) soon after diagnosis. This is important for patients with cancers of all stages. Patients with early stage colorectal cancer should have testing of their cancers for mutations in PIK3CA, PTEN, and PIK3R1 by the time they finish adjuvant treatment or after surgery if [they're] not having adjuvant treatment. Patients with metastatic colorectal cancer should have next-generation sequencing of the cancer soon after diagnosis, as the results may impact the initial systemic treatment. The NGS results are also useful for identifying clinical trial eligibility. Comorbidities will not affect the results of these biomarkers, so they should not affect the timing and decision making about ordering these tests. How does biomarker testing help the treatment and outcome of a diagnosis? Biomarkers can impact your treatment choices and outcomes. They can help doctors decide which medications will be the most effective, identify inherited features in cancer, and determine if adjuvant or additional therapies would improve outcomes. Immunotherapy responsiveness It is critical to know if a cancer has deficient DNA mismatch repair (dMMR) or high microsatellite instability (MSI-H) because these cancers can respond dramatically to immunotherapy in the early stage and metastatic settings. For example, patients with rectal cancer that is dMMR or MSI-H may have a complete clinical response with immunotherapy and may be able to avoid radiation and surgery. Thus, this testing needs to be done early, before treatment starts. Identifying Lynch syndrome Another important reason for testing for dMMR or MSI-H is to identify cancers caused by Lynch syndrome. Lynch syndrome is the most common type of inherited colorectal cancer and is caused by germline mutations in the genes that code for the DNA mismatch repair proteins or in another related gene called EPCAM. Most cancers with deficient mismatch repair or MSI-H are not caused by Lynch syndrome and occur sporadically. We don't want to miss patients with Lynch syndrome, however, because they can benefit from counseling about [the] prevention of Lynch syndrome-related cancers such as uterine cancer, ovarian cancer, and gastric cancer, in addition to colorectal cancer. When a patient is diagnosed with Lynch syndrome, family members can then be tested to see if they have Lynch syndrome. Recommendations for cancer screening at early stages are made for individuals with Lynch syndrome, and early screening can be lifesaving. Identifying treatment resistance Mutations in KRAS and NRAS make cancers resistant to anti-epidermal growth factor receptor therapy. Cancers with KRAS G12C mutations can be treated with a regimen that targets this mutation (adagrasib plus cetuximab or sotorasib plus panitumumab). There are also many clinical trials now studying RAS gene inhibitors in patients with metastatic colorectal cancer that have been previously treated. Cancers with BRAF V600E tend to be aggressive and less sensitive to chemotherapy. There is a Food and Drug Administration (FDA)-approved regimen targeting BRAF V600E (encorafenib plus cetuximab) in metastatic colorectal cancer that improves survival when added to first-line FOLFOX chemotherapy. It also improves survival as a second-line treatment after chemotherapy. Greater response to targeted and adjuvant therapy Metastatic colorectal cancers that demonstrate [the] overexpression or gene amplification of HER2 can be treated with a targeted regimen of tucatinib plus trastuzumab after initial chemotherapy. Another targeted treatment available for metastatic colorectal cancers that overexpress HER2 by IHC is trastuzumab deruxtecan. Patients with early stage colorectal cancer with mutations in the PIK3CA, PIK3R1, or PTEN genes should be treated with aspirin 160 milligrams daily for 3 years after adjuvant therapy or after surgery if [they're] not having adjuvant therapy. The ALASCCA trial, presented at ASCO GI [American Society of Clinical Oncology – Gastrointestinal Cancer] in 2025, compared a placebo to aspirin in this patient population and found that aspirin significantly lowered the rate of cancer recurrence at 3 years. This is rather new data. Oncologists are starting to order NGS testing for patients with early stage cancers in order to obtain this biomarker information. What should you ask your doctor? It's always OK to ask your doctor about biomarker testing and what it means for you. Important questions to consider include: Is my cancer dMMR/MSI-H? Am I a candidate for immunotherapy? Patients with early stage colorectal cancer should ask if aspirin therapy will be recommended based on biomarker testing. Patients with metastatic colorectal cancer should ask for the results of RAS/BRAF/HER2 testing and overall NGS testing results.
Yahoo
an hour ago
- Yahoo
Palantir and TeleTracking Team Up to Enhance Healthcare Operations Using AI-Driven Insights
TeleTracking Technologies, a leading provider of healthcare operations platforms, has teamed up with Palantir Technologies Inc. (NASDAQ:PLTR), known for its expertise in artificial intelligence systems. The two companies have formed a strategic partnership with the goal of transforming how hospitals and health systems make operational decisions, ultimately creating long-term value for healthcare providers around the world. The collaboration will integrate TeleTracking's Operations IQ platform with Palantir Technologies Inc. (NASDAQ:PLTR)'s AI-driven tools, including Foundry and AIP. This combined solution is expected to equip hospitals with near real-time, actionable insights to improve staffing efficiency, speed up decision-making, and ensure that patient needs remain the top priority. As healthcare systems continue to face increasing demands to enhance capacity and coordination without expanding their physical footprint, this partnership represents a significant step forward. By bringing together TeleTracking's operational strengths and Palantir Technologies Inc. (NASDAQ:PLTR)'s cutting-edge technology, the two aim to usher in a new era of intelligent, scalable, and efficient healthcare delivery. Alex Karp, CEO at Palantir Technologies Inc. (NASDAQ:PLTR) made the following comment: 'This partnership with TeleTracking represents the AI revolution in healthcare we are in the midst of—where we continue to move closer to a world where all hospitals and health systems are embracing, implementing and operating with an AI-powered approach, helping to streamline operations allowing for increased focus on providing the best level of care.' Palantir Technologies Inc. (NASDAQ:PLTR) is an American publicly traded company that focuses on developing software platforms designed for analyzing large volumes of data. While we acknowledge the potential of PLTR as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an extremely cheap AI stock that is also a major beneficiary of Trump tariffs and onshoring, see our free report on the best short-term AI stock. READ NEXT: and Disclosure. None. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
an hour ago
- Yahoo
New Iowa law expands cancer coverage for firefighters
A bill intended to expand cancer coverage for firefighters in Iowa is now law. Gov. Kim Reynolds signed House File 969. The bill expands the definition of cancer to include all types of cancer. Currently, only 14 cancers are currently included in coverage for firefighters, police officers and emergency responders. First responders with one of those types cancers are able to qualify for disability and death benefits. Before the passage of the bill, those with other types of cancers were not. Iowa firefighters Brian Stoaks, Mike Broderick and Malcolm Cortner all passed away from cancer. Their families and friends continued the fight until the bill passed. The bill was shot down last year. For more information, click here. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.