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‘Tumor Destroyer' shows promising results at Corewell Health

‘Tumor Destroyer' shows promising results at Corewell Health

Yahoo27-05-2025

GRAND RAPIDS, Mich. (WOOD) — Corewell Health has recently acquired a new tool to help treat patients with certain liver cancers, and the first treatments appear to be a success.
The tool was developed by , a company that spawned out of the done at the University of Michigan. It has been billed as a but Corewell Health radiologist James Morrison says the key to the tool is its precision.
'(It's) completely non-invasive, and unlike other non-invasive technologies, it doesn't damage any of the surrounding tissue. So, we can be very focused on the cancer itself and preserve as much of the normal tissue as much as possible,' Morrison told News 8.
The tool uses focused ultrasound pulses to destroy its target. The ultrasound causes bubbles to grow in the tiny gas pockets within the target tissue, causing it to expand and eventually collapse under stress, destroying the cells.
Tumor Destroyer? FDA approves tool that uses ultrasound to fight cancer
'But you could stick your hand through the beam and, as long as you're not at that one point in space, it's not going to damage any of the normal tissue,' he explained.
The by the U.S. Food and Drug Administration in 2023 and, for now, can only be used to treat cancers in the liver, but experts are confident the tool will work in other parts of the body and that approval will expand.
'Next will be the kidney and then beyond that, things like pancreatic cancer and other places in the body,' Morrison said.
Corewell Health doctors have already treated multiple patients with the HistoSonics tool and, so far, the treatments appear to be a success.
Latest trial of University of Michigan's 'tumor destroyer' exceeds goals
'Our first few patients, we (wanted to be) extra precautious and keep them in for observation. But in the future, they will go home the same day. It's well tolerated,' he said. 'Everything went smoothly. Even more smoothly than expected. … The tumor was completely ablated.'
Corewell Health is one of roughly 30 hospitals in the country to offer the new treatment.
Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

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Fungus in "agroterrorism" arrest already widely prevalent in U.S., researcher says
Fungus in "agroterrorism" arrest already widely prevalent in U.S., researcher says

CBS News

time16 minutes ago

  • CBS News

Fungus in "agroterrorism" arrest already widely prevalent in U.S., researcher says

The fungus labeled a "potential agroterrorism weapon" in a recent arrest touted by the Trump administration likely originated in North America and is already widely prevalent around the country, a researcher who studied the fungus for the federal government says. University of Michigan researcher Yunqing Jian and her boyfriend, Zunyong Liu, were charged with trying to smuggle strains of a fungus called Fusarium graminearum into the United States. Jian worked at the University of Michigan, according to officials, and Liu works at a Chinese university. The two have co-authored research into the fungus. "I can confirm that the FBI arrested a Chinese national within the United States who allegedly smuggled a dangerous biological pathogen into the country," FBI Director Kash Patel said Tuesday in a post on X. While the pathogens in the cultures seen in this photo may look similar, DNA data indicates they represent distinctly different species within the Fusarium graminearum complex. Photo by Keith Weller, USDA Agricultural Research Service According to charging documents in the case, Liu told customs officers he was trying to continue his research with the strains at the University of Michigan lab that Jian worked in, skirting the rules that require paperwork and safeguards to safely import fungi for studies. F. graminearum is already widely prevalent across the U.S. in native grasses around the country as well as crops, scientists say. It spreads and thrives usually during wet weather, causing a common crop disease called Fusarium head blight or head scab, according to the U.S. Department of Agriculture's Agricultural Research Service. "It's extremely prevalent in North America. It likely arose in North America, so it's not like a foreign agent coming in. And it's already causing a lot of problems in U.S. agriculture," Harold Kistler, an adjunct professor at the University of Minnesota, told CBS News. On the left, a healthy wheat head stands in contrast to the one on the right, which is inoculated with Fusarium graminearum and shows severe symptoms of Fusarium head blight disease. Photo by Keith Weller, USDA Agricultural Research Service Kistler said scientists believe F. graminearum likely originated in North America, because all of its closest relatives have been found on the continent. "Graminearum itself is distributed worldwide, and likely because of the distribution of grain from North America worldwide," he said. Kistler previously worked as a researcher for the USDA's Agricultural Research Service, studying fungi like F. graminearum and the crop disease it causes. While at the agency, he co-authored research with Liu and Jian uncovering new molecular clues to how the disease might be mitigated. "It's a real problem. The problem is because there's no naturally occurring resistance to the disease. And people have been trying for decades to find resistance. It's just a tough nut to crack," Kistler said of the head blight caused by F. graminearum. Farmers in the U.S. rely on a number of methods to mitigate the risk of F. graminearum, including the use of fungicides, though scientists have worried about the possibility of mutations that could make the fungicides less effective. "The fungicides are not cheap. So it's extra cost to farmers. But it's worth it because, without it, their crops could be completely lost. Not only due to yield reduction, but because what grain they may have would be contaminated with these toxins," Kistler said. Billions of dollars were lost to epidemics caused by the fungus in the 1990s, researchers and agriculture officials estimate. The Food and Drug Administration monitors for the toxins that are produced by fungi like F. graminearum, including deoxynivalenol, also called vomitoxin or DON, which can cause vomiting and diarrhea in humans who ingest too much of it. "It is not possible to completely avoid the presence of DON in wheat. DON is sometimes found in wheat grown under normal weather conditions, however, the fungus thrives in cool, wet conditions," the FDA said in a 2010 advisory to states and grain groups. Kistler said U.S. distributors also test grain for the presence of the toxins to prevent there being too much of it in the food supply. "If it's too high, they will reject it. They won't buy it. Or they will reduce the amount that they'll pay for it. If it's just marginal, they can blend it with grain that doesn't have the toxin to get below the limit of what's considered safe," he said.

Suspected Chinese bioterrorists smuggled dangerous agent into US in boots, officials say
Suspected Chinese bioterrorists smuggled dangerous agent into US in boots, officials say

Fox News

time2 hours ago

  • Fox News

Suspected Chinese bioterrorists smuggled dangerous agent into US in boots, officials say

One of the two Chinese nationals arrested for allegedly smuggling a toxic crop-killing pathogen, which also has devastating health effects on humans, stuffed the noxious fungus into her boots while entering the United States in 2022, documents show. According to an arrest affidavit for University of Michigan post-doctoral research fellow Yunqing Jian and her boyfriend, Zunyong Liu, Jian first brought Fusarium graminearum, described as a "potential agroterrorism weapon" in scientific literature, in August 2022. A transcribed WeChat conversation between Jian and Liu shows Liu instructing Jian on how to smuggle the fungus, according to the affidavit. Liu: "Teacher Liang's seeds must be placed well." Jian: "Where to put it? I only have one pair of shoes. The insole cannot be pulled off." Liu: "Did you bring just one pair of shoes?" Jian: "3 pair, wear one pair." Liu: "Where did the seeds get put? In the tube?" Jian: "I put them in my Martin boots… in a small bag. The ziplock bag. Very small." Liu: "That's good… Just put it in your shoes." Jian: "I stuffed them in the shoes." Fusarium graminearum creates "head blight," a disease of wheat, barley, maize and rice, and "is responsible for billions of dollars in economic losses worldwide each year," according to the Department of Justice. It is also toxic to humans, and can cause vomiting, liver damage, and "reproductive defects in humans and livestock." The affidavit, which said Jian has been attempting to smuggle the pathogen into the United States since she began post-doctoral studies funded by China in 2022, also accuses Jian of asking a third party to send her Fusarium graminearum in January 2024. "There are usually no problems," Jian said in a message to the third person. "Rest assured. I have mailed these before." That third person allegedly shipped the package, and hid the samples in a statistics textbook. The package was intercepted before it arrived. Jian is accused of lying on a student visa application about what exactly she planned to study in the United States. The latest smuggling attempt took place in July 2024, when Liu entered the United States at the Detroit Metropolitan Airport on a tourist visa under the guise of visiting his girlfriend, Jian, authorities said. U.S. Customs and Border Protection (CBP) flagged Liu upon his arrival, searched his luggage and conducted an interview. The luggage search "revealed a wad of tissues crumpled up in a small pocket in Liu's backpack," according to the affidavit. "The tissues concealed a note in Chinese, a round piece of filter paper with a series of circles drawn on it, and four clear plastic baggies with small clumps of reddish plant material inside," the affidavit continues. An FBI laboratory test found that the filter paper contained Fusarium graminearum, and the baggies of material contained fibrous material that was infected with Fusarium graminearum, authorities said. "In addition, the laboratory identified 10 separate samples from the filter paper," the affidavit says. "Each sample had a hand drawn circle around it, and each circle was labeled with a code containing letters and/or numbers. The sample labeled '06172' was identified by the FBI laboratory to contain the DNA sequence for Fusarium graminearum." Liu initially denied knowingly putting the pathogen in his bag, but later admitted to doing it intentionally, authorities said. He allegedly revealed his entire scheme to the investigators, including telling them that he planned to use the same laboratory that Jian used at the University of Michigan to conduct research. He said that some days during his visit, the lab would be open for use, according to the affidavit, and other days, Jian planned to let him in. Jian and Liu have been charged with conspiracy, smuggling goods into the United States, false statements and visa fraud. "This case is a sobering reminder that the Chinese Communist Party continues to deploy operatives and researchers to infiltrate our institutions and target our food supply, an act that could cripple our economy and endanger American lives," FBI Director Kash Patel told Fox News Digital in a statement. "Smuggling a known agroterrorism agent into the U.S. is not just a violation of law, it's a direct threat to national security. I commend the FBI Detroit Division and our partners at CBP for stopping this biological threat before it could do real damage." The University of Michigan released a statement regarding the incident on Wednesday. "As one of the world's leading public research institutions, the University of Michigan is dedicated to advancing knowledge, solving challenging problems and improving nearly every facet of the human experience. Our research enterprise across all three campuses is united in this commitment to serving the people of Michigan and the world," the school said. "We strongly condemn any actions that seek to cause harm, threaten national security or undermine the university's critical public mission. It is important to note that the university has received no funding from the Chinese government in relation to research conducted by the accused individuals. We have and will continue to cooperate with federal law enforcement in its ongoing investigation and prosecution." READ THE FULL AFFIDAVIT

What is Fusarium graminearum, the fungus US authorities say was smuggled in from China?

time2 hours ago

What is Fusarium graminearum, the fungus US authorities say was smuggled in from China?

NEW YORK -- Federal prosecutors charged two Chinese researchers on Tuesday with smuggling a crop-killing fungus into the U.S. last summer — charges that come amid heightened political tensions between the two countries and as the Trump administration moves to revoke visas from visiting Chinese students. Yunqing Jian and Zunyong Liu are charged with conspiracy, smuggling, making false statements and visa fraud for allegedly bringing the fungus Fusarium graminearum into the U.S. Jian, 33, was booked in a Detroit federal court. Liu, 34, is thought to be in China. According to the FBI, Liu had small baggies of the fungus stashed in his backpack when he flew to the U.S. last year and, after claiming ignorance about the plant material inside them, said he was planning to use it for research at a University of Michigan lab where Jian worked and where Liu previously worked. Fusarium graminearum causes a disease called Fusarium head blight that can wipe out cereal crops such as wheat, barley and maize and rice — it inflicts $1 billion in losses annually on U.S. wheat and barley crops, according to the U.S. Department of Agriculture. It isn't the only fungus to cause Fusarium head blight, but it's the most common culprit in the U.S. The fungus infects plants early in the growing season, shriveling wheat grains and blanching crop heads a whitish-tan color. It also causes a toxin to accumulate in wheat kernels that can make them unsafe for people and livestock to eat. Nicknamed 'vomitoxin' because it's most known for causing livestock to throw up, it can also cause diarrhea, abdominal pain, headache and fever in animals and people. Wheat and other grain crops are screened for various toxins, including Fusarium graminearum, before they can be used to feed animals and humans. Farmers have to throw out any infected grains, which can cause devastating losses. 'It's one of the many problems that farmers have to deal with that risks their livelihood,' said David Geiser, a Fusarium expert at Penn State. Although Jian and Liu are accused of smuggling Fusarium graminearum into the country, the fungus is already prevalent in the U.S. — particularly in the east and Upper Midwest — and scientists have been studying it for decades. Researchers often bring foreign plants, animals and even strains of fungi to the U.S. to study them, but they must file certain permits before moving anything across state or national borders. Studying the genes of a foreign fungus strain, for example, can help scientists learn how it tolerates heat, resists pesticides or mutates. 'We look at variations among individuals just like we do humans,' said Nicole Gauthier, a plant pathologist at the University of Kentucky who studies Fusarium. That said, it's unclear why the Chinese researchers might have wanted to bring that strain of Fusarium graminearum into the U.S. and why they didn't fill out the proper paperwork to do so. ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute's Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

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