Weight-loss drugs may lower cancer risk in people with diabetes, a study suggests
Excess body weight can raise the risk of certain cancers, leading researchers to wonder whether blockbuster drugs like Wegovy, Ozempic and Zepbound could play a role in cancer prevention.
Now, a study of 170,000 patient records suggests there's a slightly lower risk of obesity-related cancers in U.S. adults with diabetes who took these popular medications compared to those who took another class of diabetes drug not associated with weight loss.
This type of study can't prove cause and effect, but the findings hint at a connection worth exploring. More than a dozen cancers are associated with obesity.
'This is a call to scientists and clinical investigators to do more work in this area to really prove or disprove this,' said Dr. Ernest Hawk of MD Anderson Cancer Center in Houston, who was not involved in the study.
The findings were released Thursday by the American Society of Clinical Oncology and will be discussed at its annual meeting in Chicago. The study, funded by the National Institutes of Health, was led by Lucas Mavromatis, a medical student at New York University's Grossman School of Medicine.
'Chronic disease and chronic disease prevention are some of my passions,' said Mavromatis, a former research fellow with an NIH training program.
GLP-1 receptor agonists are injections used to treat diabetes, and some are also approved to treat obesity. They work by mimicking hormones in the gut and the brain to regulate appetite and feelings of fullness. They don't work for everyone and can produce side effects that include nausea and stomach pain.
In the study, researchers analyzed data from 43 U.S. health systems to compare two groups: people with obesity and diabetes who took GLP-1 drugs and other people with the same conditions who took diabetes drugs like sitagliptin. The two groups were equal in size and matched for other characteristics.
After four years, those who took GLP-1 drugs had a 7% lower risk of developing an obesity-related cancer and an 8% lower risk of death from any cause compared to those who took the other type of diabetes drug. There were 2,501 new cases of obesity-related cancer in the GLP-1 group compared to 2,671 cases in the other group.
The effect was evident in women, but not statistically significant in men. The study couldn't explain that difference, but Mavromatis noted that differences in blood drug concentration, weight loss, metabolism or hormones could be at play.
___
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute's Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Reuters
34 minutes ago
- Reuters
Indivior to delist from London Stock Exchange, maintain Nasdaq listing
June 2 (Reuters) - Pharma firm Indivior (INDV.L), opens new tab said on Monday it will cancel its secondary listing on the London Stock Exchange, effective July 25, maintaining its primary listing on the Nasdaq to reduce costs and better align with its U.S.-centric business. The company, known for its opioid addiction treatment, joins a growing number of companies delisting from London, as lower valuations and weak investor appetite continue to drive firms toward U.S. markets. Shares of Indivior, which floated in London in late 2014, have dropped more than 60% from record highs hit in June 2018. The company said over 80% of its revenue now comes from the U.S., with the Nasdaq (NDAQ.O), opens new tab accounting for about 75% of recent trading volumes. The delisting aims to streamline operations and reflect the company's strategic focus on the U.S. market, it said. Indivior moved its primary listing to the United States last year. The decision to delist from London comes just months after Indivior overhauled its management. Earlier this year, it appointed David Wheadon as chair and Joe Ciaffoni as CEO.
Geeky Gadgets
36 minutes ago
- Geeky Gadgets
Unlock this Secret Workflow Hack that Combines Claude 4 & Gemini 2.5
What if the secret to unlocking your most productive workflow wasn't about choosing the best tool, but about how you combine them? In a world where artificial intelligence is reshaping how we work, the pairing of Claude 4 and Gemini 2.5 offers a innovative approach that many professionals are overlooking. Imagine seamlessly transitioning from raw data analysis to polished storytelling, or from technical precision to strategic insight—all within one integrated system. These two AI powerhouses, each with their own unique strengths, aren't just tools; they're collaborative partners that can transform the way you tackle complex projects. Yet, most people miss the opportunity to harness their full potential together. In this perspective, Grace Leung explores how Claude 4 and Gemini 2.5 complement each other to create a workflow that's both efficient and impactful. You'll discover how Gemini's technical prowess in processing multimodal data and Claude's strategic depth in refining insights can work in tandem to elevate your results. Whether you're managing large datasets, crafting compelling narratives, or making high-stakes decisions, this workflow offers a fresh way to approach your challenges. By the end, you might just rethink how you integrate AI into your daily processes—and uncover untapped possibilities hiding in plain sight. Claude 4 & Gemini 2.5 Synergy What Makes Each AI Model Unique? Claude 4 and Gemini 2.5 are designed to address different challenges, making them ideal partners for a wide range of workflows. Their distinct strengths complement each other, allowing users to tackle complex tasks with greater ease and precision. Gemini 2.5: Renowned for its speed, scalability, and ability to handle large datasets, Gemini 2.5 is a robust tool for technical and data-intensive tasks. Its extensive context window allows it to process multimodal inputs, including text, images, and structured data. This makes it particularly valuable for analyzing complex datasets, building prototypes, or managing large-scale projects. Gemini's technical efficiency ensures reliable and consistent results, even under demanding conditions. Renowned for its speed, scalability, and ability to handle large datasets, Gemini 2.5 is a robust tool for technical and data-intensive tasks. Its extensive context window allows it to process multimodal inputs, including text, images, and structured data. This makes it particularly valuable for analyzing complex datasets, building prototypes, or managing large-scale projects. Gemini's technical efficiency ensures reliable and consistent results, even under demanding conditions. Claude 4: Focused on strategy, storytelling, and detailed analysis, Claude 4 excels in refining insights and crafting polished outputs. Its autonomous memory system enables it to maintain contextual understanding across multiple stages of a project, making sure seamless updates and continuity. Claude is particularly effective for high-level decision-making, creating visually engaging presentations, and developing narratives that resonate with audiences. How to Combine Their Strengths To fully harness the potential of Claude 4 and Gemini 2.5, a sequential workflow that uses their individual strengths is recommended. This approach ensures that each model contributes its unique capabilities to the overall process. 1. Begin with Gemini 2.5: Start by using Gemini to process and analyze large datasets or multimodal inputs. Its technical precision and scalability provide a solid foundation for your project, allowing you to extract raw insights and identify key patterns efficiently. 2. Transition to Claude 4: Once the data has been processed, shift to Claude for deeper analysis, storytelling, and strategic refinement. Claude's ability to contextualize information and present it in a compelling manner ensures that your outputs are both insightful and impactful. This workflow allows you to combine Gemini's technical expertise with Claude's strategic depth, resulting in outputs that are both data-driven and contextually rich. By dividing tasks according to each model's strengths, you can save time while making sure high-quality results. The Workflow Most People Miss : Claude 4 + Gemini 2.5 Watch this video on YouTube. Explore further guides and articles from our vast library that you may find relevant to your interests in Claude 4. Practical Applications The integration of Claude 4 and Gemini 2.5 offers fantastic potential across various industries. Their combined capabilities can be applied to a wide range of scenarios, enhancing workflows and delivering superior outcomes. Strategic Dashboards: Use Gemini to analyze large datasets and extract raw insights. Claude can then organize these insights into actionable intelligence, complete with visual aids and strategic recommendations tailored to decision-makers. Use Gemini to analyze large datasets and extract raw insights. Claude can then organize these insights into actionable intelligence, complete with visual aids and strategic recommendations tailored to decision-makers. Audience Intelligence: Process customer data with Gemini to uncover trends, behaviors, and preferences. Claude can interpret this data to craft targeted messaging and develop marketing campaigns that resonate with specific audiences. Process customer data with Gemini to uncover trends, behaviors, and preferences. Claude can interpret this data to craft targeted messaging and develop marketing campaigns that resonate with specific audiences. AI-Powered Speaking Coaching: Analyze speaking patterns and presentation data using Gemini. Claude can refine scripts, suggest improvements, and even generate audio for practice sessions, helping users enhance their communication skills. Analyze speaking patterns and presentation data using Gemini. Claude can refine scripts, suggest improvements, and even generate audio for practice sessions, helping users enhance their communication skills. Visual Storytelling for Presentations: Gemini provides the data analysis needed for creating charts, graphs, and visuals. Claude transforms these into compelling narratives, making sure that presentations are both informative and engaging. Gemini provides the data analysis needed for creating charts, graphs, and visuals. Claude transforms these into compelling narratives, making sure that presentations are both informative and engaging. Collaborative Critique Workflow: Let Gemini generate initial outputs, such as drafts or prototypes, and have Claude critique and enhance them. This iterative process ensures polished, high-quality deliverables that meet professional standards. Why This Workflow Works The effectiveness of this workflow lies in the complementary nature of Claude 4 and Gemini 2.5. Gemini handles the heavy lifting of data processing and analysis, providing a strong technical foundation. Claude, on the other hand, refines and contextualizes the results, adding strategic depth and narrative clarity. This division of labor not only streamlines the workflow but also ensures that the final outputs are both accurate and meaningful. By combining these models, you can achieve a balance between technical precision and strategic insight. This approach is particularly valuable for professionals who need to manage complex projects, make data-driven decisions, or communicate findings effectively. Additional Insights Claude 4's autonomous memory system plays a crucial role in managing project contexts, making sure that no detail is overlooked, even in multi-stage workflows. This feature is especially useful for long-term projects that require consistent updates and contextual understanding. Meanwhile, Gemini's ability to process multimodal inputs and scale efficiently makes it indispensable for handling data-heavy tasks. Together, these models provide a comprehensive solution for professionals seeking to optimize their workflows with AI. Rather than viewing Claude 4 and Gemini 2.5 as standalone tools, consider them as collaborative partners. Their combined strengths allow you to approach tasks with both technical accuracy and strategic foresight. By integrating these models into your workflow, you can elevate your work to new levels of efficiency and impact. Whether you're analyzing data, crafting narratives, or making high-level decisions, this duo offers a powerful way to achieve your goals. Media Credit: Grace Leung Filed Under: AI, Guides Latest Geeky Gadgets Deals Disclosure: Some of our articles include affiliate links. If you buy something through one of these links, Geeky Gadgets may earn an affiliate commission. Learn about our Disclosure Policy.
Geeky Gadgets
36 minutes ago
- Geeky Gadgets
Trae AI: The Free AI Coding Tool That's Smarter Than Your IDE
What if your coding environment could think, adapt, and evolve alongside your projects—without costing you a dime? Enter Trae AI, a free alternative to traditional coding IDEs that's redefining the way developers approach their work. Unlike its well-known competitors like Visual Studio Code, Trae AI doesn't just stop at being functional; it's designed to be fantastic. With features like customizable coding agents and seamless integration of innovative AI models, this platform promises to streamline workflows, boost productivity, and empower developers to tackle even the most complex challenges. Whether you're debugging intricate code or experimenting with AI-driven applications, Trae AI offers a modern solution that's as versatile as it is powerful. In this breakdown, Prompt Engineering explore how Trae AI sets itself apart from the crowd. From its innovative Multi-Contextual Prompt Systems (MCPS) to its robust privacy measures, this IDE is packed with tools that cater to both the creative and technical needs of developers. You'll discover how Trae AI's AI model compatibility can push the boundaries of your projects and why its thoughtful design makes it accessible for developers of all skill levels. But is it truly the free, all-in-one solution it claims to be? Let's unpack its features, benefits, and potential limitations to see if Trae AI lives up to its bold promise of being the ultimate coding companion. Overview of Trae AI IDE TL;DR Key Takeaways : Trae AI is a free, modern IDE designed to rival platforms like Visual Studio Code, offering advanced customization, seamless AI integration, and robust privacy measures. Customizable coding agents with Multi-Contextual Prompt Systems (MCPS) streamline workflows, improve precision, and adapt to specific project needs. Supports integration with advanced AI models like Gemini 2.5 Pro, GPT-4.1, and Cloud 3.5 Sonnet, along with custom AI models via API keys for innovation and experimentation. Features include a clean user interface, real-time code execution previews, integrated web search, and tools for diverse projects like text-to-image generation and REST API integration. Emphasizes data privacy and security with local data storage, encrypted transmissions, and regional compliance options, making sure a secure development environment. Customizable Coding Agents for Enhanced Productivity A standout feature of Trae AI is its customizable coding agents, which are designed to streamline workflows and improve precision. These agents use Multi-Contextual Prompt Systems (MCPS) to handle complex, multi-layered instructions, allowing you to adapt tools and workflows to specific tasks. This level of customization ensures that your coding environment evolves alongside your projects, whether you're debugging intricate code, scripting automation processes, or developing APIs. By tailoring these agents to your unique requirements, you can significantly boost both productivity and accuracy, making Trae AI a powerful tool for developers seeking efficiency. Seamless AI Model Integration for Advanced Development Trae AI supports a wide range of advanced AI models, including Gemini 2.5 Pro, GPT-4.1, and Cloud 3.5 Sonnet. This compatibility allows you to select the model that best aligns with your project goals, making sure optimal performance and precision. Additionally, the platform offers the flexibility to integrate custom AI models via API keys, allowing experimentation and innovation. This feature is particularly beneficial for developers working on AI-driven applications, machine learning projects, or other innovative technologies. By providing seamless integration with these models, Trae AI enables you to push the boundaries of what is possible in software development. Free Cursor Alternative Trae AI Coding Assistant Gain further expertise in AI Coding IDE by checking out these recommendations. Features That Simplify and Enhance Your Workflow Trae AI is equipped with a robust set of features designed to simplify coding tasks and enhance overall productivity. Key highlights include: A clean and intuitive user interface that assists easy navigation and efficient project management. that assists easy navigation and efficient project management. Integrated web search capabilities , allowing you to access relevant information without leaving the IDE. , allowing you to access relevant information without leaving the IDE. Preconfigured MCPS options for quick access to documentation, examples, and templates . . Real-time code execution and output previews, allowing you to test and refine your code efficiently. These features work cohesively to create a seamless development experience, saving you time and effort while making sure high-quality results. Whether you're a beginner or an experienced developer, Trae AI's thoughtful design makes it accessible and practical for a wide range of users. Versatility Across Diverse Projects Trae AI's versatility makes it an ideal choice for a broad spectrum of applications. For example, the platform supports the development of text-to-image generators by integrating APIs such as Google's Gemini API. With built-in tools for image generation, regeneration, and downloading, Trae AI caters to both creative and technical projects. Additionally, its support for REST APIs simplifies the integration of external services, allowing you to expand the scope of your projects. Whether you're building innovative applications or managing routine tasks, Trae AI provides the tools and flexibility needed to bring your ideas to life. Privacy and Security: A Foundational Priority Trae AI places a strong emphasis on data privacy and security, making sure that your work remains protected at all times. The platform stores data locally and uses temporary uploads only for processing tasks, minimizing the risk of unauthorized access. All transmissions are encrypted, and strict access controls are implemented to safeguard your files. Furthermore, regional data deployment options allow you to comply with local regulations, making Trae AI a reliable choice for developers handling sensitive or confidential information. This commitment to security ensures peace of mind, allowing you to focus on your projects without concerns about data breaches or compliance issues. Optimized Usability for Developers of All Levels Designed with both simplicity and functionality in mind, Trae AI is particularly well-suited for small to medium-sized projects. Features such as code diffs and inline editing make it easy to track changes and refine your work, while the platform's extensive customization options allow you to tailor the environment to your specific needs. Although some AI models may have rate limits, Trae AI's comprehensive feature set ensures that it remains a strong alternative to traditional IDEs. Best of all, the platform is completely free, making it accessible to developers of all experience levels, from beginners to seasoned professionals. A Modern IDE Built for Today's Developers Trae AI stands out as a robust and secure coding IDE that prioritizes customization, functionality, and user experience. By integrating advanced AI models, customizable coding agents, and strong privacy measures, it offers a comprehensive solution for developers seeking a modern and efficient coding environment. Whether you're working on innovative AI applications, creative projects, or routine programming tasks, Trae AI equips you with the tools and flexibility to succeed. With its free access and versatile features, Trae AI is a valuable resource for developers looking to enhance their workflows and achieve their goals. Media Credit: Prompt Engineering Latest Geeky Gadgets Deals Some of our articles include affiliate links. If you buy something through one of these links, Geeky Gadgets may earn an affiliate commission. Learn about our Disclosure Policy
