logo
The UK's own global health security depends on continued investment in disease research

The UK's own global health security depends on continued investment in disease research

Telegraph25-04-2025

By 2040, the £3 billion of global health research and development (R&D) funding invested by the United Kingdom since 1994 will have saved 1.43 million lives, averted 99 million disability-adjusted life years (DALYs) and prevented 183 million cases of neglected disease.
Behind each one of the numbers is a person, a family, a community whose lives have been saved or changed for the better. We believe that as one of the richest nations in the world, the UK has an ethical responsibility to take a lead on breakthroughs in neglected diseases.
But the case for continued support and investment is much stronger than just ethical responsibility; there are widespread and measurable economic and social benefits not only in the countries where these diseases occur but in the UK itself.
A new report, by Impact Global Health in collaboration with Liverpool School of Tropical Medicine, found that the UK directly benefits from R&D investment into diseases like malaria, HIV and tuberculosis.
It shows that the UK economy would gain an additional boost of £7.7 billion and 4,000 additional jobs by 2040 from public funding of neglected disease R&D. Some £6 billion has already been gained but around £1.5 billion, equivalent to an average of £100 million a year, is yet to be felt and is contingent on funding being sustained.
And the benefits to the UK of investment in global health do not stop there.
Now is the time for bold action
Covid-19, and the West African Ebola epidemic demonstrated that infections don't recognise geographic borders. Nobody is safe from future pandemics until everybody has access to effective diagnostics, drugs and treatments and robust health systems.
Put simply: the UK's own global health security depends on continued investment in this early pipeline of global health R&D.
Yet 2025 has been a challenging year for global health – with significant cuts announced to critical funding internationally and continued uncertainty about future investment. Already, many projects have been forced to pause or stop, causing a direct negative impact on the people and communities which are most in need.
In an age where there are multiple calls on government and other budgets, global health R&D could be seen, mistakenly, as an easy target. But the impact of R&D funding in the UK and across the globe should not be underestimated.
This latest research clearly shows how this funding has already significantly improved health outcomes and positively impacted individual lives and wider society. We must keep this momentum to realise these benefits into the future.
There is a very real risk that funding cuts now or in the future will reduce the impact of what has already been achieved and will lose the opportunity to develop new products, save even more lives and create even more sustained economic benefit. Any reduction in investment could rapidly unravel the substantial progress made to date, leaving future advances in life-saving interventions in jeopardy.
Now is the time for bold action to protect critical investment in this area. Every pound of funding lost will negatively impact the UK economy, make the UK more vulnerable to future pandemics, and most importantly, expose the most vulnerable communities around the world to greater health threats.
The UK has been a leader in funding and conducting research and development targeted at neglected diseases over the last two decades. Along with saving countless lives within some of the world's poorest communities, that investment has had real health and economic benefits in the UK.

Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

Awkward! How the new chairman of Reform UK called party leader Nigel Farage 'an idiot' and branded his comments about HIV-infected migrants using the NHS 'prejudiced'
Awkward! How the new chairman of Reform UK called party leader Nigel Farage 'an idiot' and branded his comments about HIV-infected migrants using the NHS 'prejudiced'

Daily Mail​

time8 hours ago

  • Daily Mail​

Awkward! How the new chairman of Reform UK called party leader Nigel Farage 'an idiot' and branded his comments about HIV-infected migrants using the NHS 'prejudiced'

Reform UK's new chairman once called leader Nigel Farage an 'idiot', it emerged last night. Dr David Bull, who was unveiled as Zia Yusuf's replacement, also branded as 'prejudiced' comments that Mr Farage had made about HIV-infected migrants using the NHS. The remarks surfaced just hours after Dr Bull gave his maiden speech as chairman and threatened to overshadow his appointment, while at a Press conference unveiling the new chairman, Mr Farage unexpectedly ruled out putting the return of the death penalty on Reform's manifesto at the next general election. Dr Bull's comments, first reported by The Daily Telegraph, were made on social media in 2014. He posted them after Mr Farage, then leader of his previous party UKIP, suggested that HIV-positive immigrants should not be allowed to come to the UK and receive treatment on the NHS. He said it should not be used as a 'global health service', adding: 'I do not think people with life-threatening diseases should be treated by our National Health Service, and that is an absolute essential condition for working out a proper immigration policy.' Sharing an article about Mr Farage's comments, Dr Bull wrote on X/ Twitter: 'Nigel Farage's comments are ill-judged, prejudiced and dangerous. HIV can affect anyone regardless of sex, race and class.' In the post, still visible online, he added: '#idiot #unhelpful.' Dr Bull, 56, is a long-time ally of Mr Farage and has held roles in both Reform and its former iteration, the Brexit Party. He served as an MEP for North West England between 2019 and 2020. Mr Farage said that Dr Bull would bring 'terrific verve, energy, enthusiasm' to his new role. Mr Yusuf plunged the party into turmoil on Thursday after announcing his shock resignation on social media, giving Mr Farage only ten minutes' notice. He said he was quitting after attacking one of his own MPs, Sarah Pochin, for calling for a burka ban during Prime Minister's Questions. But just 48 hours after leaving, he said he was returning to the party. The 38-year-old businessman said his resignation had been 'born of exhaustion' after working for the party for 11 months 'without a day off'. He will now lead Reform's Elon Musk-inspired Doge unit, which the party says will root out wasteful spending in the ten councils it controls, starting in Kent. The decision not to include anything in Reform's manifesto about the death penalty will likely disappoint millions of its voters. A poll by the think-tank More In Common in January found nearly eight in ten of its backers support it 'for certain crimes'. Mr Farage said 'nothing on the death penalty will be part of [Reform] party policy' and that 'personally I don't think I could ever support it'. He said he was opposed because of hundreds of 'quite serious miscarriages of justice' having emerged since the 70s, adding that he believed it will become a big national issue because of polling suggesting younger generations are increasingly in favour. It may lead to suspicions that Mr Farage is trying to make Reform UK appear less Right-wing and controversial as it increasingly tries to target Labour voters. It also emerged that Reform lost nearly 3,500 members in the past week amid the Yusuf fiasco.

US aid cuts threaten South Africa's status as powerhouse of HIV and tuberculosis research
US aid cuts threaten South Africa's status as powerhouse of HIV and tuberculosis research

Telegraph

time17 hours ago

  • Telegraph

US aid cuts threaten South Africa's status as powerhouse of HIV and tuberculosis research

South Africa risks losing its status as a powerhouse of HIV and tuberculosis research as sweeping American funding cuts jeopardise dozens of experimental trials. At least 27 HIV trials and another 20 TB trials in the country have been put at risk by Donald Trump's deep cuts to foreign assistance and global health spending, new analysis shows. Loss of the trials would hit research projects looking for new vaccines into both infections, as well as new long-lasting protective medicines and studies into the best way to treat children. Having intense HIV and TB epidemics as well as world class universities and research institutes has made South Africa a leader in combating the two diseases. Yet while the research has often been led by South African scientists, it has overwhelmingly been conducted with international funding, particularly with 20 years of generous United States government aid spending. Prof Salim Abdool Karim, director of the Centre for the Aids Program of Research in South Africa, said: 'The US is such a big player in our country – South Africa is a powerhouse in medical research because of what the US spends.' The bulk of funding for research came from the US National Institutes of Health (NIH), with the country receiving an estimated £111m ($150m) each year. Prof Ntobeko Ntusi, the president and chief executive of the South African Medical Research Council (SAMRC), said earlier this year: 'In many ways the South African health research landscape has been a victim of its own success, because for decades we have been the largest recipients of both [official development assistance] funding from the US for research [and] also the largest recipients of NIH funding outside of the US.' Now, unless alternative sources of money can be found, South African academic and research institutes could lose about 30 per cent of their annual income and may be forced to lay off hundreds of staff, the analysis found. 'There's been a huge dependence on US funding. The loss of it for South Africa means the cancellation of a huge amount of research,' said Tom Ellman, director of the MSF's Southern Africa Medical Unit (SAMU). The joint analysis by Treatment Action Group (TAG) and Doctors Without Borders (MSF) of NIH-funded research found 39 TB and HIV clinical research sites are under threat, placing at least 27 HIV trials and 20 TB trials at risk. The effect of cuts could be wider still, with research also funded through other US channels, including the US President's Emergency Plan for Aids Relief (Pepfar), which has been slashed by Donald Trump's administration. Global research 'in peril' Lindsay McKenna, TB project co-director of TAG said: 'Public funding from the US government to South Africa is the scaffold on which pharmaceutical companies, philanthropies, and other governments invest in transformative TB and HIV science.' 'These ongoing funding disruptions by the US government don't just affect US-funded research projects, they put in peril a much wider ecosystem of global research.' Dr Ellman said a combination of the infections found in South Africa, its research base and its strong grass roots activism had combined, with US funding, to make the country so prominent in research. He said: 'For years, South Africa has spearheaded the research and development of critical innovative medical tools for the prevention, diagnosis, treatment and care of HIV and TB which have saved lives not just within South Africa's borders, but also in communities worldwide.' The country has more HIV patients than any other, with an estimated 8 million currently infected and 105,000 deaths annually. The high prevalence of HIV goes hand-in-hand with a high prevalence of tuberculosis, because TB takes advantage of patients' weakened immune systems. Tuberculosis is the biggest cause of death among those with HIV in South Africa, which recorded 54,000 TB deaths in 2023. At the same time, the country has strong research institutions and universities, and a history of medical innovation, including conducting the first heart transplant in 1969. Finally, the history of the apartheid struggle, and later the fight in the early 2000s to get antiretroviral drugs in the face of government AIDS denialism, has produced well-organised and politically-engaged health activists. According to the joint analysis, HIV trials now at risk include studies into using broadly neutralising antibodies (bNAbs) to find a cure, and also trials into long-lasting anti-HIV preventative jabs. The Brilliant Consortium, a collaboration of African researchers led by the SAMRC working to develop an HIV vaccine, lost all funding even as it was about to begin an early stage vaccine trial. Dr Ellman said: 'I think it would be a disaster if we gave up on the hope of finding an effective vaccine for HIV. All of that has been done with South Africa and without access to South African research and communities, it's not going to be possible.' The emergence of some resistance to antiretroviral drugs has also highlighted the importance of trials to find new drugs which can deal with the phenomenon. HIV trials are also looking at honing and improving existing treatment regimes, as well as simplifying and rolling out expensive techniques first used in the developing world. TB trials at risk include studies for new drugs and shorter, safer regimens for treatment and prevention. The cuts have a ripple effect beyond individual trials, because they also weaken research infrastructure which is used and relied on by other funders. That could have a knock-on effect on trials looking at new TB jab possibilities, including the promising new M72/AS01E vaccine candidate. South Africa is now scrabbling for alternative sources of funding to try to salvage as many of the research projects as possible. Dr Ellman said: 'We call on all potential donors to step up, as without sustained investment, we will never end these deadly epidemics.'

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into the world of global news and events? Download our app today from your preferred app store and start exploring.
app-storeplay-store