Dose by dose: Story of India's vaccine evolution
As we enter World Immunisation Week, it would be interesting to look at India's immunisation journey which began over two centuries ago when the country's first smallpox vaccine was administered in Mumbai in 1802, laying the foundation for public preventative health care.
More than a century later, preventative immunisation began in earnest in 1948 with the adoption of the International Tuberculosis Campaign, an initiative designed to stop the potentially deadly bacterial disease that mainly affects the lungs and killed an estimated 500,000 people a year in India in the late 1940s.
Yet it wasn't until 1978 that India reached a turning point in its vaccine delivery framework and ability to deliver broader protective health care at scale. That year, the country launched the Expanded Programme on Immunisation (EPI)—later renamed the Universal Immunisation Programme (UIP)— providing free vaccines against 12 vaccine-preventable diseases, including tuberculosis, polio, measles, and hepatitis B for mothers and children.
Today, it stands as one of the world's largest public health programmes, and as one of the world's largest national immunisation programmes, the UIP reaches over 2.67 crore newborns and 2.9 crore pregnant women annually.
Notably, under the aegis of UIP, polio eradication became one of the earliest and most prominent successes for Indian health care. Thanks to years of sustained immunisation drives and nationwide campaigns, and to support from policymakers, health workers, volunteers, Rotary clubs, and other partners, India, part of the World Health Organization's Southeast Asia Region, was certified polio-free in 2014—a significant model for the world to follow.
Despite the country's success in stopping polio, high population density, poor sanitation, the prevalence of marginalised and/or inaccessible communities, and vaccine hesitancy remained. These public health challenges led our government to launch Mission Indradhanush (MI) in December 2014.
Concentrated on 'addressing gaps in immunisation coverage and ensuring that essential vaccines reach those who need them most,' MI focuses on vaccinating women and children against a host of diseases, including diphtheria, pertussis, tetanus, polio, and tuberculosis, meningitis and pneumonia caused by haemophilus influenzae. The initiative has completed twelve phases so far, covering 554 districts across the country, and will continue to provide immunisation coverage to those in need.
In 2023-24, India reached full, national immunisation coverage — a milestone made possible through the consistent and extensive efforts of programs like UIP and MI. Alongside domestic progress, India is also ensuring global progress toward equitable access to vaccines as the largest vaccine producer in the world. Covering 60% of the global vaccine supply, India is remarkably one of the biggest suppliers of low-cost vaccines in the world. During the pandemic, India exported over 298 million Covid-19 vaccine doses to nearly 100 countries during the Vaccine Maitri initiative.
Now, Artificial Intelligence (AI)-integrated innovations such as the Electronic Vaccine Intelligence Network (eVIN) app, a platform that electronically tracks vaccine supply, allow us to further modernise health care delivery across the nation.
This article is authored by Deepak Kapur, chairman, Rotary International India's National PolioPlus Committee (RI-INPPC).
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


Indian Express
an hour ago
- Indian Express
Measles spike in US shows how vaccine hesitancy threatens decades of public-health progress
Vaccines are critical tools for the containment and elimination of infectious diseases. They work not merely by protecting individuals, but by reducing community transmission. There have been several global pushes to improve vaccine uptake over the years, but one major coordinated effort occurred in 2021 in response to the Covid pandemic, which saw the most rapid vaccine introduction in history. Globally, the years with the most vaccine introductions have typically coincided with public health initiatives, funding boosts, or as a response to pandemics. The 1980s and 1990s saw WHO's Expanded Programme on Immunisation (EPI) with DTP (diphtheria-tetanus-pertussis), polio, measles, BCG (tuberculosis) vaccines and Hepatitis B and Hib vaccines introduced in the late 1990s. The 2000s saw accelerated introductions of Hepatitis B, Haemophilus influenzae type B (Hib), and yellow fever vaccines in low-income countries, marking a shift in global access to routine vaccines. The introduction of new and underused vaccines like pneumococcal conjugate vaccine (PCV), rotavirus vaccine, HPV and Measles-Rubella (MR) vaccine marked the next decade. The United States is currently experiencing a significant resurgence of measles, with 1,046 confirmed cases as of May 27. This marks a sharp increase from previous years, with the majority of cases occurring among unvaccinated individuals in regions with declining immunisation rates. Measles was officially eliminated from the US in 2000. This implies that new cases occur only when someone contracts measles abroad and returns to the country. A new study from Johns Hopkins points out that the significant drop in childhood vaccination rates is concerning because herd immunity requires at least 95 per cent vaccination coverage. The MMR vaccine is probably one of the most effective vaccines. A single dose gives 93 per cent protection from infection, and two doses up to 98 per cent. Measles, which can be deadly for unvaccinated children, is highly contagious. Factors like post-pandemic vaccine hesitancy, non-evidence-based fears of the association between the MMR vaccine and autism, and the complacency of populations who may not remember the long-term sequelae of measles infection are behind the dwindling measles vaccination rates in the US. Measles is often regarded as the 'canary in the coalmine' — if cases spread, it is a warning that other disease outbreaks might spring up where there are gaps in vaccination coverage. Its resurgence in the US is a global warning that even advanced health systems are vulnerable without consistent immunisation. Globally, only 83 per cent of children received the first dose of the measles vaccine in 2023; 74 per cent received the second dose. These figures fall short of the 95 per cent coverage needed to prevent outbreaks. India has made significant strides in its immunisation efforts, particularly under the UIP. India achieved a national immunisation coverage of 93.5 per cent in 2023–24, indicating that the majority of children received all recommended vaccines by the age of two. Since its inception, Mission Indradhanush, focused on areas with low immunisation rates, has completed 12 phases, vaccinating 5.46 crore children and 1.32 crore pregnant women across 554 districts. However, the measles upsurge in the US shows one cannot ignore increasing vaccine hesitancy, particularly since it threatens to throw away the gains made in the containment of infectious diseases. In resource-limited settings, this can lead to healthcare systems being overwhelmed and a general delay in uptake of new vaccines. Misinformation has contributed significantly to the declining uptake for vaccines. The flu vaccination rates among NHS staff in the UK, for instance, dropped to their lowest in nearly 15 years in 2024-25. So far, India has remained immune to vaccine hesitancy. Previous experience with successful vaccination campaigns and government endorsements have played an important role in creating a positive perception of vaccines. However, we must remain alert and actively consider putting in place a multi-pronged, culturally nuanced plan to address vaccine hesitancy. The writer is senior scientist, ICMR


Time of India
5 hours ago
- Time of India
NO2 levels in city's air three times higher than safe limits
Gurgaon: Concentration of nitrogen dioxide (NO2) -- a pollutant emitted by burning fuel in vehicles, power plants and industries – exceeded the maximum safe limit by three times in the past two days. Data from the Gwal Pahari air quality monitoring station showed that average NO2 for eight hours was 133µg/m³ on Thursday and 123µg/m³ on Friday. In India, the safe limit for exposure to NO2 is 40µg/m³. The maximum concentration considered safe by the World Health Organization is even lower, at 25 µg/m³. Experts said emissions from vehicles, especially in congested areas, is likely to be the key reason for NO2 pollution. They said NO2 does not get as much regulatory attention as other pollutants such as particulate matter (PM2.5 and PM10), though it is associated with exacerbating respiratory ailments. Shubhansh Tiwari, a research associate at the Centre for Science and Environment (CSE), said on Friday, "Elevated NO₂ levels in the city are predominantly due to vehicular emissions. Old vehicles and traffic congestion are key sources of NO2 here." by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Giao dịch CFD với công nghệ và tốc độ tốt hơn IC Markets Đăng ký Undo Asked about action taken to reduce NO2 emissions, an official of the Haryana State Pollution Control Board (HSPCB) said the agency has allowed a private firm to scrap old vehicles. "This aims to remove polluting vehicles from city roads," the official said. A senior HSPCB official said NO2 levels are likely to have spiked after brief relief due to pre-monsoon showers. "The recent rains had kept nitrogen dioxide levels in check by dispersing pollutants. But with clear skies and calmer weather now, NO2 from vehicular and industrial emissions is building up, especially in traffic-dense areas. Unlike particulate matter, NO2 often flies under the radar, but prolonged exposure can be equally hazardous," the official said. Currently, just one of the four air quality monitoring stations is functioning in the city. Dr Bandana Mishra, who heads the pulmonology and respiratory medicine department at Manipal Hospital in Gurgaon said everyone is at risk from high NO2 exposure, but children and the elderly suffer the most. "Nitrogen dioxide exposure can lead to increased inflammation of the airways, which results in persistent cough wheezing, reduced lung function and a higher frequency of asthma attacks," Dr Mishra said. Get the latest lifestyle updates on Times of India, along with Eid wishes , messages , and quotes !


New Indian Express
6 hours ago
- New Indian Express
When diseases cross borders, so must solidarity
Even as the US, led by President Donald Trump, withdrew from global health engagements through a petulant exit from the World Health Organization (WHO) and the evisceration of its international aid agency, two events in Geneva on May 19 unfurled the flag of global solidarity. One, international negotiations on the Pandemic Treaty ended, with all participating WHO members agreeing on the final text. The treaty was cheered by an anxious world badly bruised by Covid's devastation and wary of more zoonotic pandemics on the horizon. It is the second-ever global health treaty to be concluded under auspices of the WHO, after the Framework Convention for Tobacco Control adopted in 2003. The second was the convening of a forum—Digital Health Without Borders—to advance digital health applications across the world with impact, efficiency and equity. The event, organised by Dr Rajendra Gupta from India, was addressed by WHO's Director General Tedros Adhanom Ghebreyesus and leading digital technology experts as well as prominent representatives from the domains of medicine, nursing and public health. They advocated universal access to impactful digital health technologies to prevent pandemics and promote primary care-led universal health coverage. These affirmations of a 'one world' approach are reassuring in a polarised political environment where the US and some other countries are retreating from adherence to principles of global solidarity. While the US and Argentina have quit the WHO, western European nations like the Netherlands and Germany have reduced their commitments to global aid. Trump and Musk have eviscerated USAID, which was a major contributor to global health programmes aimed at tackling infectious diseases like HIV-AIDS and tuberculosis, as well as maternal and child health protection. Scientific agencies like the National Institutes of Health have been disconnected from global research.