Scientists use dogs to track down dangerous insects: 'Easier for a dog to smell something than it is for a human to see something'
The Wildlife Society reports that organizations like the New York-New Jersey Trail Conference and Working Dogs for Conservation are putting dogs and their keen sense of smell to good use in the fight against an invasive species: the spotted lanternfly. Sightings of the destructive insect were first confirmed in 2014 in Pennsylvania and have reached at least 18 other states.
As the referenced study published in Ecosphere discovered, humans have spotted visible eggs in vineyards, but canines had 3.4 times more detections than people in more complex areas where the insects overwinter, such as forests. In other words, they can sniff out invasions that aren't obvious to humans.
"The dogs find egg masses by smell," Angela Fuller, professor in the Department of Natural Resources and the Environment at Cornell University, told The Wildlife Society. "So, in a very complex environment, it's easier for a dog to smell something than it is for a human to see something that is small and cryptic."
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These insects are harmful to the environment as they destroy vegetation, including trees. Infestations have killed off entire wine vines in a single growing season.
When plants and trees die, so do several animal habitats and food sources, such as those for beneficial pollinators at the start of the food chain. Most of the planet's oxygen also comes from trees and grass — one tree alone can produce enough oxygen for four people, reports the U.S. Department of Agriculture. Therefore, recruiting pups to protect the health of the plants in these forests and vineyards helps many.
A collaboration between working dogs and nature trails is the perfect storm to battle this invasion. The New York-New Jersey Trail Conference boasts over 2,000 volunteers who help keep trails safe. Working Dogs for Conservation gives shelter dogs new life by training them to sniff out biological threats like invasive seedlings.
The collaboration began in 2019, when experts trained a labrador retriever and a Belgian malinois to find live spotted lanternflies through positive reinforcement. Eventually, training evolved into having the dogs identify egg masses, specifically the ones belonging to the lanternflies.
Other important finds by these working dogs have included Chinese bush clover in Iowa and Yellow star thistle in Colorado. The canines even help the biosecurity of an area by distinguishing between disease-infected and uninfected scat from animals of the same species.
The New York-New Jersey Trail Conference has been building and cleaning trails since 1923. You can do your part by keeping areas clean and alerting local authorities if you spot an invasive species.
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CBS News
7 hours ago
- CBS News
NYU researchers developing technology to detect hidden GPS trackers
Many people use GPS every day, but in the wrong hands, it's a terrifying tool that can help stalkers track their victims. It's been difficult for victims to detect hidden trackers – until now. CBS News New York investigative reporter Tim McNicholas got a look at a promising development from New York University researchers. How to know if there's a GPS tracker on you Mo Satt, a researcher at NYU's Tandon School of Engineering, says there are already ways to detect Bluetooth trackers like Apple AirTags, but solutions are few for GPS trackers. "If a cyber stalker is looking to track someone, they're not gonna use an AirTag because Apple and Samsung and Android have figured out a way to alert people," he said. So, Satt started using a device already on the market called a spectrum analyzer to track signals from nearby electronics. He realized, unlike phones and other devices, GPS trackers send out signals like clockwork to save battery, typically every minute on the dot while moving. That allows him to distinguish a GPS tracker from other devices. Now, he and a team of researchers are working to develop a way for stalking victims to detect those same unique signals. "They won't have to be looking at spikes [on a spectrum analyzer], right? They're just gonna have an app or something that will Bluetooth to their phone, that will talk to a device like this [spectrum analyzer] and say you, with a high degree of probability, you have a tracker with you," Satt said. Satt and his team are now trying to secure additional investors and support to turn their plans into reality. They're presenting their findings this summer at a major cybersecurity conference, and victim advocates say their work, so far, sounds very promising. Man fatally shot in Queens after gunman stuck GPS tracker on car Their research was inspired by tragedies like the death of Tyrone Jones, who was fatally shot inside his car in St. Albans, Queens. The vehicle was riddled with 11 bullets. "There were so many spectators," said Donaya McMillan, Jones' cousin. "It was something that, to this day, I still have nightmares about. As much as I try to remember the beautiful, big smile he has, sometimes I also think about how he looked in that moment." Queens District Attorney Melinda Katz said the shooter, Isaiah Stokes, was hellbent on revenge after Jones asked him to leave a party. According to prosecutors, Stokes – a well-known actor who appeared on shows including "Law and Order," "The Americans" and "Blue Bloods" – stuck a GPS tracker on the bottom of Jones' car a week before the shooting. A judge sentenced Stokes to 25 years to life in prison for the murder in March. McMillan thinks if the technology Satt and his team are developing had been available at the time, her cousin might still be alive. "I think that he would've been able to identify that he was being tracked," she said. "This could've been prevented." While an external GPS tracker was used in this case, many newer cars have tracking software built into the car. Unfortunately, people can be stalked even without someone sneaking a tracker into the car. CBS News New York has reported on stalking victims whose abusive exes still have access to the car's system.

Associated Press
a day ago
- Associated Press
Neuroscience Based Medications Offer Hope in Addiction Crisis, Says NYC Doctor
Breakthrough Approach to Addiction : NYC Psychiatrist Calls for New Treatment Paradigm Targeting Brain Circuitry Disrupted by Substance Use Disorders 'Neuroscience—Based Medications offer hope in Addiction Crisis'— Eileen DiFrancesco MD NEW YORK, NY, UNITED STATES, June 8, 2025 / / -- Breakthrough Approach to Addiction Treatment Targets Underlying Neural Circuitry Disrupted by Substance Use Disorders Dr. Eileen DiFrancesco , a board certified psychiatrist and expert in psychopharmacology is calling for a paradigm shift and how addiction is treated in the United States. Drawing on over two decades of clinical experience and emerging neuroscientific evidence, Dr. DiFrancesco advocates for the immediate integration of new medications that act on the brain core regulatory systems – specifically those impaired in addiction. These are not traditional addiction, medication, says Dr. DiFrancesco they are part of the new generation of treatments designed to restore function to brain regions disrupted by chronic substance use – including those responsible for impulse control, motivation, and decision-making. Her call comes at a critical moment. According to the most recent national survey, over 48 million Americans suffered from a substance used disorder in the past year. Alcohol alone is linked to an estimate estimated 178,000 deaths annually in the U.S., Representing more than 4 million years of potential life lost Brain Imaging studies by leading scientists have consistently shown that individuals with addiction exhibit profound changes in the prefrontal cortex and related neural circuits that regulate reward, impulse control, and emotional processing. Dr. DiFrancesco argues that the most promising treatments are those that directly target these biological deficits – not just the symptoms of addiction We've reached a tipping point where we can no longer afford to separate addiction from the brain science that explains it, she states this is not about willpower or moral failure. It's about using medications that help normalize the very brain systems that have been hijacked. Dr. DiFrancesco's public appeal follows the release of her educational video, where she explained how modern neuroscience is reshaping our understanding of addiction – and how under utilize treatments may offer new hope to patients and families alike. About Dr. Eileen DiFrancesco Dr. DiFrancesco is a board certified psychiatrist with over 25 years of experience practicing in New York City. She is a recognized leader in psychiatry and psychopharmacology. Before entering private practice, she held triple title at New York Hospital, Cornell and Rockefeller university in the laboratory for biology of addictive diseases. She studied early onset schizophrenia using pet scans, positive emission tomography with Richard M. Pico at Mount Sinai. In addition She spent from almost a decade working with E. Roy. John, who developed quantitative electroencephalography, QEEG also known as brain mapping. Media Contact: XSRXDOCTOR 18 EAST 63RD STREET NEW YORK, NY 10065 PHONE; (917) 699-7845 Email: [email protected] Eileen DiFrancesco M.D. Xsrxdoctor +1 917-699-7845 email us here Legal Disclaimer: EIN Presswire provides this news content 'as is' without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.


Associated Press
a day ago
- Associated Press
Dupixent® (dupilumab) Data at Revolutionizing Atopic Dermatitis (RAD) Conference Reinforce Use in Atopic Dermatitis Patients with Skin of Color
Atopic dermatitis is a chronic disease that disproportionately impacts communities of color Dupixent achieved 75% or greater improvement in overall disease severity, the primary endpoint, in more than three-quarters of treated patients Patients experienced substantial reductions in hyperpigmentation, dry skin and itch from baseline Results support commitment to enhance clinical understanding of chronic diseases in communities of color TARRYTOWN, N.Y. and PARIS, June 07, 2025 (GLOBE NEWSWIRE) -- Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today presented results from the DISCOVER Phase 4, single-arm, open-label trial assessing Dupixent® (dupilumab) in adults and adolescents with moderate-to-severe atopic dermatitis with skin of color. These are the first clinical trial results for Dupixent in a large population of patients with darker skin tones. The results, along with the Dupixent Phase 3 trials, demonstrated patients taking Dupixent experienced improvements in signs and symptoms of atopic dermatitis from baseline across many skin tones. The data were shared in an oral presentation at the 2025 Revolutionizing Atopic Dermatitis (RAD) Conference. 'Atopic dermatitis, a chronic disease with underlying type 2 inflammation, has a high prevalence and quality of life impact on patients with skin of color. Unique clinical features like darker patches of hyperpigmentation versus redness typically seen on lighter skin may lead to less accurate diagnoses and underestimation of disease severity,' said Andrew Alexis, M.D., M.P.H., Professor of Clinical Dermatology at Weill Cornell Medicine. 'The results from the DISCOVER trial showed that Dupixent patients with atopic dermatitis and darker skin not only experienced reduced disease severity and itch but also saw improvements in areas of particular concern including dyspigmentation and dry skin. These data deepen the clinical understanding of atopic dermatitis within this underserved population, including use of newly validated scales.' In the trial, 120 patients with atopic dermatitis and skin of color (82% Black, 11% Asian, 2% American Indian/Alaska Native, 5% Arab, Central American or other) were treated with Dupixent every two weeks using a weight-based dosing regimen. At 24 weeks: The safety results in the DISCOVER trial were generally consistent with the known safety profile of Dupixent in its approved dermatological indications. The overall rate of adverse events (AEs; n=124) in the DISCOVER trial was 42%, with the most common (≥2%) AEs being headache (3%), upper respiratory tract infection (2%), eczema (2%), conjunctivitis (3%) and allergic conjunctivitis (2%). About Atopic Dermatitis in Skin of Color Atopic dermatitis is a chronic skin disease with underlying type 2 inflammation that causes intense, persistent itch and skin lesions that cover much of the body, resulting in skin dryness, cracking, pain, crusting and oozing. In patients with skin of color, the type and location of the lesions can vary, and they are more likely to have hardened skin lesions and severe skin dryness, itch, dyspigmentation and greater disease severity than those with lighter skin. Additionally, redness that is observed on lighter skin typically appears as darkened, grey or violet on darker skin tones. Because the disease presents differently in people with skin of color, it can be misdiagnosed or the severity underestimated, which can contribute to higher levels of healthcare resource utilization. About the DISCOVER Clinical Trial The DISCOVER Phase 4 open-label, single-arm trial evaluated the efficacy and safety of Dupixent in adults and adolescents aged 12 years and older with moderate-to-severe atopic dermatitis and skin of color, as defined by Fitzpatrick skin types IV-VI (those with high melanin; light brown to black). During the 24-week treatment period, all patients in the trial received Dupixent monotherapy every two weeks based on weight after a loading dose: patients weighing ≥30 to <60 kg received 200 mg and patients weighing ≥60 kg received 300 mg. The primary endpoint assessed the proportion of patients who achieved at least 75% improvement on the Eczema Area and Severity Index (EASI-75) at 24 weeks. Secondary endpoints included the proportion of patients who achieved ≥4-point improvement on the Peak-Pruritus Numerical Rating Scale (PP-NRS) at 24 weeks. Additional endpoints included pigmentary changes on the clinician-reported Post-Inflammatory Hyperpigmentation Severity Scale (PHSS; scale: 0-8) and skin dryness on the newly developed patient-reported Xerosis NRS (X-AD; scale: 0-10) at 24 weeks. About Dupixent Dupixent, which was invented using Regeneron's proprietary VelocImmune® technology, is a fully human monoclonal antibody that inhibits the signaling of the interleukin-4 (IL-4) and interleukin-13 (IL-13) pathways and is not an immunosuppressant. The Dupixent development program has shown significant clinical benefit and a decrease in type 2 inflammation in Phase 3 trials, establishing that IL-4 and IL-13 are two of the key and central drivers of the type 2 inflammation that plays a major role in multiple related and often co-morbid diseases. Dupixent has received regulatory approvals in more than 60 countries in one or more indications including certain patients with atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), eosinophilic esophagitis (EoE), prurigo nodularis, chronic spontaneous urticaria (CSU) and chronic obstructive pulmonary disease (COPD) in different age populations. More than 1,000,000 patients are being treated with Dupixent globally.1 About Regeneron's VelocImmune Technology Regeneron's VelocImmune technology utilizes a proprietary genetically engineered mouse platform endowed with a genetically humanized immune system to produce optimized fully human antibodies. When Regeneron's co-Founder, President and Chief Scientific Officer George D. Yancopoulos was a graduate student with his mentor Frederick W. Alt in 1985, they were the first to envision making such a genetically humanized mouse, and Regeneron has spent decades inventing and developing VelocImmune and related VelociSuite ® technologies. Dr. Yancopoulos and his team have used VelocImmune technology to create a substantial proportion of all original, FDA-approved fully human monoclonal antibodies. This includes Dupixent® (dupilumab), Libtayo® (cemiplimab-rwlc), Praluent® (alirocumab), Kevzara® (sarilumab), Evkeeza® (evinacumab-dgnb), Inmazeb® (atoltivimab, maftivimab and odesivimab-ebgn) and Veopoz® (pozelimab-bbfg). In addition, REGEN-COV® (casirivimab and imdevimab) had been authorized by the FDA during the COVID-19 pandemic until 2024. Dupilumab Development Program Dupilumab is being jointly developed by Regeneron and Sanofi under a global collaboration agreement. To date, dupilumab has been studied across more than 60 clinical trials involving more than 10,000 patients with various chronic diseases driven in part by type 2 inflammation. In addition to the currently approved indications, Regeneron and Sanofi are studying dupilumab in a broad range of diseases driven by type 2 inflammation or other allergic processes in Phase 3 trials, including chronic pruritus of unknown origin, bullous pemphigoid, and lichen simplex chronicus. These potential uses of dupilumab are currently under clinical investigation, and the safety and efficacy in these conditions have not been fully evaluated by any regulatory authority. U.S. INDICATIONS DUPIXENT is a prescription medicine used: DUPIXENT is not used to relieve sudden breathing problems and will not replace an inhaled rescue medicine. DUPIXENT is not used to treat any other forms of hives (urticaria). IMPORTANT SAFETY INFORMATION Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®. Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you: Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines; have asthma and use an asthma medicine; or have atopic dermatitis, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, prurigo nodularis, chronic obstructive pulmonary disease, or chronic spontaneous urticaria, and also have asthma. Do not change or stop your other medicines, including corticosteroid medicine or other asthma medicine, without talking to your healthcare provider. This may cause other symptoms that were controlled by those medicines to come back. DUPIXENT can cause serious side effects, including: The most common side effects include: Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088. Use DUPIXENT exactly as prescribed by your healthcare provider. It's an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it's recommended DUPIXENT be administered by or under supervision of an adult. In children 6 months to less than 12 years of age, DUPIXENT should be given by a caregiver. Please see accompanying full Prescribing Information including Patient Information. About Regeneron Regeneron (NASDAQ: REGN) is a leading biotechnology company that invents, develops and commercializes life-transforming medicines for people with serious diseases. Founded and led by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to numerous approved treatments and product candidates in development, most of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurological diseases, hematologic conditions, infectious diseases, and rare diseases. Regeneron pushes the boundaries of scientific discovery and accelerates drug development using our proprietary technologies, such as VelociSuite, which produces optimized fully human antibodies and new classes of bispecific antibodies. We are shaping the next frontier of medicine with data-powered insights from the Regeneron Genetics Center® and pioneering genetic medicine platforms, enabling us to identify innovative targets and complementary approaches to potentially treat or cure diseases. For more information, please visit or follow Regeneron on LinkedIn, Instagram, Facebook or X. About Sanofi Sanofi is an R&D driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. We apply our deep understanding of the immune system to invent medicines and vaccines that treat and protect millions of people around the world, with an innovative pipeline that could benefit millions more. Our team is guided by one purpose: we chase the miracles of science to improve people's lives; this inspires us to drive progress and deliver positive impact for our people and the communities we serve, by addressing the most urgent healthcare, environmental, and societal challenges of our time. Sanofi is listed on EURONEXT: SAN and NASDAQ: SNY. Regeneron Forward-Looking Statements and Use of Digital Media This press release includes forward-looking statements that involve risks and uncertainties relating to future events and the future performance of Regeneron Pharmaceuticals, Inc. ('Regeneron' or the 'Company'), and actual events or results may differ materially from these forward-looking statements. Words such as 'anticipate,' 'expect,' 'intend,' 'plan,' 'believe,' 'seek,' 'estimate,' variations of such words, and similar expressions are intended to identify such forward-looking statements, although not all forward-looking statements contain these identifying words. These statements concern, and these risks and uncertainties include, among others, the nature, timing, and possible success and therapeutic applications of products marketed or otherwise commercialized by Regeneron and/or its collaborators or licensees (collectively, 'Regeneron's Products') and product candidates being developed by Regeneron and/or its collaborators or licensees (collectively, 'Regeneron's Product Candidates') and research and clinical programs now underway or planned, including without limitation Dupixent®(dupilumab); uncertainty of the utilization, market acceptance, and commercial success of Regeneron's Products and Regeneron's Product Candidates and the impact of studies (whether conducted by Regeneron or others and whether mandated or voluntary), including the studies discussed or referenced in this press release, on any of the foregoing; the likelihood, timing, and scope of possible regulatory approval and commercial launch of Regeneron's Product Candidates and new indications for Regeneron's Products, such as Dupixent for the treatment of chronic pruritus of unknown origin, bullous pemphigoid, lichen simplex chronicus, and other potential indications; the ability of Regeneron's collaborators, licensees, suppliers, or other third parties (as applicable) to perform manufacturing, filling, finishing, packaging, labeling, distribution, and other steps related to Regeneron's Products and Regeneron's Product Candidates; the ability of Regeneron to manage supply chains for multiple products and product candidates and risks associated with tariffs and other trade restrictions; safety issues resulting from the administration of Regeneron's Products (such as Dupixent) and Regeneron's Product Candidates in patients, including serious complications or side effects in connection with the use of Regeneron's Products and Regeneron's Product Candidates in clinical trials; determinations by regulatory and administrative governmental authorities which may delay or restrict Regeneron's ability to continue to develop or commercialize Regeneron's Products and Regeneron's Product Candidates; ongoing regulatory obligations and oversight impacting Regeneron's Products, research and clinical programs, and business, including those relating to patient privacy; the availability and extent of reimbursement or copay assistance for Regeneron's Products from third-party payors and other third parties, including private payor healthcare and insurance programs, health maintenance organizations, pharmacy benefit management companies, and government programs such as Medicare and Medicaid; coverage and reimbursement determinations by such payors and other third parties and new policies and procedures adopted by such payors and other third parties; changes in laws, regulations, and policies affecting the healthcare industry; competing drugs and product candidates that may be superior to, or more cost effective than, Regeneron's Products and Regeneron's Product Candidates (including biosimilar versions of Regeneron's Products); the extent to which the results from the research and development programs conducted by Regeneron and/or its collaborators or licensees may be replicated in other studies and/or lead to advancement of product candidates to clinical trials, therapeutic applications, or regulatory approval; unanticipated expenses; the costs of developing, producing, and selling products; the ability of Regeneron to meet any of its financial projections or guidance and changes to the assumptions underlying those projections or guidance; the potential for any license, collaboration, or supply agreement, including Regeneron's agreements with Sanofi and Bayer (or their respective affiliated companies, as applicable), to be cancelled or terminated; the impact of public health outbreaks, epidemics, or pandemics on Regeneron's business; and risks associated with litigation and other proceedings and government investigations relating to the Company and/or its operations (including the pending civil proceedings initiated or joined by the U.S. Department of Justice and the U.S. Attorney's Office for the District of Massachusetts), risks associated with intellectual property of other parties and pending or future litigation relating thereto (including without limitation the patent litigation and other related proceedings relating to EYLEA®(aflibercept) Injection), the ultimate outcome of any such proceedings and investigations, and the impact any of the foregoing may have on Regeneron's business, prospects, operating results, and financial condition. A more complete description of these and other material risks can be found in Regeneron's filings with the U.S. Securities and Exchange Commission, including its Form 10-K for the year ended December 31, 2024 and its Form 10-Q for the quarterly period ended March 31, 2025. Any forward-looking statements are made based on management's current beliefs and judgment, and the reader is cautioned not to rely on any forward-looking statements made by Regeneron. Regeneron does not undertake any obligation to update (publicly or otherwise) any forward-looking statement, including without limitation any financial projection or guidance, whether as a result of new information, future events, or otherwise. Regeneron uses its media and investor relations website and social media outlets to publish important information about the Company, including information that may be deemed material to investors. Financial and other information about Regeneron is routinely posted and is accessible on Regeneron's media and investor relations website ( and its LinkedIn page ( Sanofi Disclaimers or Forward-Looking Statements This media update contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates regarding the marketing and other potential of the product, or regarding potential future revenues from the product. Forward-looking statements are generally identified by the words 'expects', 'anticipates', 'believes', 'intends', 'estimates', 'plans', and similar expressions. Although Sanofi's management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of Sanofi, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. These risks and uncertainties include among other things, unexpected regulatory actions or delays, or government regulation generally, that could affect the availability or commercial potential of the product, the fact that product may not be commercially successful, the uncertainties inherent in research and development, including future clinical data and analysis of existing clinical data relating to the product, including post marketing, unexpected safety, quality or manufacturing issues, competition in general, risks associated with intellectual property and any related future litigation and the ultimate outcome of such litigation, and volatile economic and market conditions, and the impact that global crises may have on us, our customers, suppliers, vendors, and other business partners, and the financial condition of any one of them, as well as on our employees and on the global economy as a whole. The risks and uncertainties also include the uncertainties discussed or identified in the public filings with the SEC and the AMF made by Sanofi, including those listed under 'Risk Factors' and 'Cautionary Statement Regarding Forward-Looking Statements' in Sanofi's annual report on Form 20-F for the year ended December 31, 2024. Other than as required by applicable law, Sanofi does not undertake any obligation to update or revise any forward-looking information or statements. All trademarks mentioned in this press release are the property of the Sanofi group except for VelociSuite and Regeneron Genetics Center . 1 Data on File