INmune Bio's Alzheimer's drug fails to meet main goal in mid-stage study
(Reuters) -INmune Bio said on Monday its experimental Alzheimer's drug failed to improve cognitive functions in patients with early stages of the mind-robbing disease in a mid-stage study, sending its shares plunging nearly 59% in premarket trading.
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Business Insider
2 hours ago
- Business Insider
Indian geologists head to Zambia to explore cobalt, copper under landmark 9,000km² deal
India has dispatched a team of geologists to Zambia to begin surveying a vast 9,000 square kilometre zone allocated for the exploration of critical minerals, including cobalt and copper. India dispatched geologists to Zambia to survey a vast area for critical minerals. The focus is on cobalt and copper exploration to support clean energy initiatives. Zambia's mineral reserves are pivotal for global energy transitions and economic partnerships. This move is part of India's accelerating efforts to secure key raw materials essential to its clean energy transition and electric vehicle (EV) manufacturing ambitions. The Indian geologists are focused on locating cobalt—a critical component in batteries for electric vehicles and mobile phones—as well as scouting for copper, which plays a vital role in power generation, electronics, and construction. According to Indian government sources cited by Reuters, the geological team will assess the mineral potential of the allocated land—an area roughly the size of Cyprus—over a multi-year program. Earlier this year, India announced plans to explore and mine critical minerals in the Democratic Republic of the Congo, Zambia, Tanzania, and Australia. Mines Secretary V.L. Kantha Rao said the government is working with an Indian mining firm - KABIL and other partners to secure mineral assets in these countries through diplomatic missions. " We will take two to three years in doing this exploration and we hope that after exploration we will be able to get the mining rights also," Rao said. According to sources, the geological team will conduct multiple visits to the African nation during the project's duration. Upon evaluating the region's mining potential, the Indian government plans to seek a mining lease from Zambian authorities and potentially partner with private companies for the development phase. Zambia's vast mineral deposits Zambia is Africa's second-largest copper producer, trailing only the Democratic Republic of the Congo. Earlier this year, Zambia agreed to grant India exclusive rights to explore this zone. The country also holds significant reserves of cobalt and other critical minerals that are increasingly vital to the global energy transition. However, the nation's mining sector has not fully lived up to its potential in recent years. Challenges such as underinvestment, policy uncertainty, and infrastructure constraints have hindered growth and deterred major international players. Despite these obstacles, Zambia remains a key target for countries seeking to diversify mineral supply chains away from traditional markets. With renewed government efforts to attract foreign investment and modernize the mining industry, Zambia is positioning itself as a strategic hub for the exploration and export of minerals essential to the global shift toward clean energy and digital technologies. As major economies seek to reduce dependence on China and diversify supply chains, countries like India are intensifying their outreach to resource-rich African nations. Zambia, which has been courting foreign investors to revive its mining sector, views partnerships like this as key to unlocking new revenue streams and boosting domestic capacity. Last year, U.S.-based KoBold Metals, backed by billionaires including Bill Gates and Jeff Bezos, announced the discovery of a major copper deposit in Zambia—an important milestone in the country's push to position itself within the global energy transition. At the same time, Zambia made strides in attracting electric vehicle (EV) investments, with Build Your Dreams (BYD), the world's largest EV manufacturer, expanding into the country through a partnership with Pilatus Electric Mobility Zambia Limited (PEM). Together, these developments signal rising investor confidence in Zambia's strategic position within the global EV supply chain, further showcasing the country's vast mineral potential and reinforcing the government's efforts to attract foreign investment aimed at reviving and expanding its mining sector.
Time Business News
3 hours ago
- Time Business News
Understanding Neurology: The Cornerstone of Brain and Nervous System Health
Neurology, a vital branch of medicine, focuses on diagnosing, treating, and managing disorders of the nervous system. This complex system, comprising the brain, spinal cord, and peripheral nerves, governs every bodily function—from movement and sensation to cognition and emotion. As the medical community advances neurology has become increasingly important in improving quality of life for patients suffering from neurological disorders. This article explores the significance of neurology, common neurological conditions, modern diagnostic techniques, treatment approaches, and future directions in this ever-evolving field. What Is Neurology? Neurology is the specialized medical discipline concerned with disorders of the nervous system. Neurologists study the anatomy, functions, and pathologies related to the brain, spinal cord, nerves, and muscles. Unlike psychiatry, which deals primarily with mental health disorders, neurology addresses physical dysfunctions arising from nerve damage or disease. The nervous system controls vital processes, including: Voluntary and involuntary movements Sensory perceptions such as touch, pain, and temperature Coordination and balance Memory, thinking, and emotions Regulation of organs and glands When something disrupts these functions, neurology steps in to understand and manage the underlying causes. Common Neurological Disorders Neurology covers a wide spectrum of conditions. Some of the most prevalent neurological disorders include: 1. Stroke A stroke occurs when blood flow to parts of the brain is interrupted, leading to tissue damage. It is a leading cause of disability and requires immediate neurological intervention. 2. Epilepsy Characterized by recurrent seizures, epilepsy results from abnormal electrical activity in the brain. Neurologists diagnose seizure types and customize medication regimens. 3. Multiple Sclerosis (MS) An autoimmune disorder, MS causes the immune system to attack nerve coverings, leading to muscle weakness, vision problems, and coordination issues. 4. Parkinson's Disease This progressive disorder affects movement due to the loss of dopamine-producing neurons, causing tremors, stiffness, and slow movements. 5. Alzheimer's Disease and Dementia Neurology also addresses cognitive decline conditions, including Alzheimer's, which affects memory and reasoning skills. 6. Peripheral Neuropathy Damage to peripheral nerves causes numbness, pain, or weakness, often related to diabetes or injury. Diagnostic Advances in Neurology The complexity of neurological disorders demands precise diagnostic tools. Recent technological advancements have transformed how neurologists assess nervous system health: Magnetic Resonance Imaging (MRI) MRI provides detailed images of brain and spinal cord structures without radiation exposure. Functional MRI (fMRI) highlights active brain regions during tasks. Computed Tomography (CT) Scan CT scans quickly detect brain hemorrhages, tumors, and other acute abnormalities, crucial in stroke diagnosis. Electroencephalogram (EEG) EEG measures electrical activity in the brain, helping diagnose epilepsy and other seizure disorders. Nerve Conduction Studies and Electromyography (EMG) These tests assess nerve and muscle function, essential in diagnosing peripheral neuropathy and neuromuscular diseases. Lumbar Puncture (Spinal Tap) Analyzing cerebrospinal fluid can reveal infections, inflammation, or bleeding affecting the nervous system. Treatment Modalities in Neurology Neurological treatment is multifaceted, often combining medication, therapy, and sometimes surgery: Pharmacological Treatments Medications like antiepileptics, muscle relaxants, and dopamine agonists play a central role in managing neurological diseases. Physical and Occupational Therapy Rehabilitation helps patients regain mobility, strength, and independence after neurological injuries or disease progression. Surgical Interventions Procedures such as deep brain stimulation for Parkinson's or removal of brain tumors are critical for select patients. Lifestyle and Supportive Care Diet, exercise, counseling, and caregiver support improve overall patient outcomes and quality of life. The Role of Neurology in Modern Healthcare Neurology is pivotal in addressing the growing burden of neurological diseases worldwide. With aging populations and rising prevalence of chronic conditions, neurologists are essential in early diagnosis, intervention, and long-term management. Furthermore, neurology intersects with other specialties such as psychiatry, rehabilitation medicine, and neurosurgery, fostering a multidisciplinary approach that enhances patient care. Future Directions in Neurology Exciting innovations are shaping the future of neurology: Precision Medicine Tailoring treatments based on genetic and biomarker information promises more effective and individualized care. Neurotechnology Emerging tools like brain-computer interfaces and advanced neurostimulation devices are revolutionizing treatment options. Artificial Intelligence (AI) AI algorithms improve diagnostic accuracy by analyzing complex imaging and clinical data. Regenerative Medicine Research into stem cells and nerve regeneration offers hope for repairing damaged nervous tissue. Conclusion Neurology remains a cornerstone of modern medicine, dedicated to unraveling the mysteries of the nervous system and improving countless lives. With advancements in diagnostics, therapeutics, and technology, neurologists are better equipped than ever to tackle the challenges posed by neurological disorders. For healthcare professionals and patients alike, staying informed about the latest developments in neurology is vital. Whether it's managing chronic diseases like Parkinson's or addressing acute conditions such as stroke, the field of neurology continues to evolve—offering new hope, better outcomes, and a deeper understanding of the human brain and nervous system. TIME BUSINESS NEWS
Business Insider
3 hours ago
- Business Insider
South Africa's Ramaphosa makes fresh demands as Trump's tariff deadline approaches
As the July 9 deadline for the implementation of President Trump's tariffs approaches, South Africa's President Cyril Ramaphosa has renewed calls for extended negotiations with the United States. South African President Cyril Ramaphosa advocated for continued negotiations with the United States regarding looming tariffs. The current tariff proposal includes a 31% rate on U.S. imports from South Africa, prompting Pretoria to request a reduction to 10%. The Trump administration asserts that these measures address trade imbalances and protect domestic industries. Pretoria's Department of Trade, Industry and Competition confirmed on Tuesday that South Africa has formally requested more time to finalize a trade agreement before the 31% tariff on U.S. imports from South Africa takes full effect. According to a statement from South Africa's Department of Trade, Industry and Competition, the country is pushing for a worst-case tariff cap of 10% as negotiations with the United States continue. Reuters reports that South African officials recently met with Assistant U.S. Trade Representative for Africa, Connie Hamilton, in Luanda, where they were informed that Washington is developing a standardized template for its trade engagements with African nations. ' In view of this development... African countries, including South Africa, have advocated for the extension of the 90-day deadline to enable countries to prepare their proposed deals in accordance with the new template,' the department said. Trump's trade tariff Recall that U.S. President Donald Trump issued a decree imposing tariffs that range from 10% for countries such as Kenya, Ghana, and Ethiopia, to as high as 30% for South Africa and 50% for Lesotho, as part of his administration's broader recalibration of trade relations with Africa. The tariff, initially announced in April as part of Trump's broader ' reciprocal trade ' policy, was temporarily paused for 90 days to allow room for negotiations. However, with the grace period nearing its end, pressure is mounting on both sides to reach a compromise that preserves South Africa's preferential access to the U.S. market under frameworks like the African Growth and Opportunity Act (AGOA). Ramaphosa's administration argues that the tariffs disproportionately harm South African manufacturers and exporters, many of whom rely on the U.S. as a key market. The South African government has emphasized its long-standing economic and diplomatic ties with Washington, positioning the current dispute as a test of mutual cooperation under changing global trade dynamics. The Trump administration, however, maintains that the tariffs are necessary to correct what it sees as imbalanced trade practices and to protect American industries from unfair competition.
