What is gestational diabetes?
(NewsNation) — Diabetes affects the lives of tens of millions of Americans.
Gestational diabetes is part of this total but specifically affects 5% to 9% of pregnant women in America, per the CDC.
As the name suggests, it is a variant of diabetes that forms in a woman during pregnancy.
Oftentimes, it develops around the 24th week of pregnancy in cases where the body is unable to produce adequate amounts of insulin to combat increased blood sugar levels.
The increased blood sugar levels are a result of hormonal changes throughout the gestation period.
Per the Centers for Disease Controla nd Prevention, symptoms often do not appear.
If they do exist, they are generally mild and can involve urinating more frequently than usual and being thirstier than usual.
The CDC recommends that women be tested to determine if they have gestational diabetes.
The National Institute of Diabetes and Digestive and Kidney Diseases recommends losing extra weight before getting pregnant if you are overweight.
Regularly being physically active before and during pregnancy can decrease the likelihood of developing gestational diabetes.
If one develops gestational diabetes, the likelihood of type 2 diabetes can be heightened, but can be somewhat curtailed by making healthy choices, per the NIDDK.
Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


Medscape
29 minutes ago
- Medscape
Experimental MS Drug Nearly Eliminates Disease Activity
PHOENIX — Frexalimab, a second-generation anti-CD40 ligand monoclonal antibody provides extended tight control of multiple sclerosis (MS) whether measured by relapse or brain imaging at 2-year follow-up, results of an open-label extension (OLE) of a phase 2 trial showed. 'At week 96, there was almost complete suppression of new gadolinium-enhancing lesions with very similar pattern seen with new or enhancing T2 lesions,' said study investigator Stephen Krieger, MD, professor of neurology, Icahn School of Medicine at Mount Sinai, New York City. Two phase 3 international studies with this drug are already enrolling. 'Part of the interest in frexalimab and anti-CD40 therapies is the idea that one can modulate both B- and T-cell activity without cell depletion,' explained Krieger, who presented the long-term open-label data on May 29 at the Consortium of Multiple Sclerosis Centers (CMSC) 2025 Annual Meeting. Near Complete Disease Suppression The latest data suggest frexalimab is fulfilling its promise. Over follow-up to date, there has been nearly complete suppression of gadolinium-enhancing (Gd+) lesions on MRI among those taking the dose now being tested in the phase 3 trials. At 2 years, with an annualized relapse rate of 0.08%, 92% of patients were relapse-free. The randomized portion of this phase 2 trial attracted attention when it was published a year ago in The New England Journal of Medicine , but the 2-year results showed that the efficacy and safety observed at 12 weeks persist. In the controlled trial, 129 patients with relapsing MS were randomized to 300-mg, 400-mg, 600-mg, or 1200-mg frexalimab or matching placebos. Suppression of Gd+ lesions was the primary endpoint. At 12 weeks, the adjusted mean of new Gd+ lesions was 1.4 in the combined placebo groups but 0.3 in the 300-mg frexalimab group and 0.2 in the 1200-mg group. Of those who participated in the randomized portion of the phase 2 trial, 97% continued into the long-term OLE. The OLE consisted of two arms: 1200-mg frexalimab administered intravenously every 4 weeks or 300-mg frexalimab administered subcutaneously every 2 weeks. At the end of 2 years, when 82% of those enrolled in the OLE were still on medication, the adjusted mean for new T1-weighted Gd+ lesions ranged from 0.1 to 0.3 across study arms whether on continuous frexalimab or switched from placebo to frexalimab. For those who were initiated on the 1200-mg dose in the controlled portion of the trial and remained on this dose for the OLE, the mean was 0.1. For the secondary endpoint of new or enlarging T2 lesions, the suppression at 2 years was almost the same. Again, the adjusted mean for new lesions across all arms ranged from 0.1 to 0.3. For those receiving the 1200-mg dose, the mean was 0.2. Mean T2 lesion volume increased in the placebo arm but not in the treatment arms during the randomized phase. After entering the OLE, T2 lesion volume fell in placebo patients now on active therapy. In the 1200-mg arm, the fall in lesion volume during the randomized phase continued into the first 24 weeks of the OLE. After 24 weeks, the lesion volume remained suppressed with no return toward baseline. Those initiated on placebo never caught up after switching to frexalimab. Relapse Rare — 2% at 96 Weeks On the 1200-mg dose of frexalimab, only 8% had any relapse recorded over the extended follow-up. In half, there was a single relapse. Only 2% had three or more relapses. While the Expanded Disability Status Scale score declined slightly among placebo patients once started on active therapy, there was no change from baseline through 96 weeks in patients started on any active therapy. As postulated by earlier preclinical and clinical studies, frexalimab had no effect on lymphocyte counts over time. Over the 96-week follow-up, levels of immunoglobulins remained unchanged, according to Krieger who showed graphs with straight lines for these values over the course of the OLE. Due to the potential of suppressing activation of both T and B cells over time, anti-CD40 therapies have long been considered a promising mechanism for control of MS. However, clinical development of first-generation drugs was abandoned because of an association with thromboembolism. 'Frexalimab has been engineered to avoid these events through a change in the Fc receptors with reduces downstream inflammatory events,' said Krieger. The long-term data support this premise. Over 2 years, there was one pulmonary embolism, but this exception was observed in a patient with a viral illness and a genetic predisposition for an inflammatory response, according to Krieger. When surveying other adverse events, 'nothing jumps out' in the OLE relative to the randomized phase. One potential exception is a rise in liver function tests observed in two (4%) patients on the 1200-mg dose. Only one of these patients discontinued therapy, and the levels returned to normal over time in both. The effects of the anti-CD40 mechanism on both the adaptive and innate immune systems suggest frexalimab might offer efficacy for both progressive and relapsing MS. In the ongoing phase 3 program, one of the trials (FREXALT) is enrolling patients with relapsing MS. The other (FREVIVA) is enrolling patients with progressive disease. Fulfilling its Promise Commenting on the results, Amit Bar-Or, MD, Chief of the Multiple Sclerosis Division, the Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, described frexalimab as 'a very interesting drug.' He agreed that the CD40 ligand is a promising target in MS but cautioned that these phase 2 data cannot answer the most interesting questions. This includes the more robust evidence of safety and efficacy from phase 3 trials, but it remains unclear whether the benefits extend beyond controlling relapsing disease. 'I think there is particular interest in whether it will also show extended benefit in progressive MS, and this will be a major focus of interest from the next set of studies,' Bar-Or said.


CBS News
an hour ago
- CBS News
Texas woman dies from brain-eating amoeba after using tap water for sinus rinse
How to stay safe from the brain-eating amoeba Parasite called Naegleria fowleri has been found in several states and is blamed for 3 deaths in the U.S. this year Parasite called Naegleria fowleri has been found in several states and is blamed for 3 deaths in the U.S. this year A Texas woman died from an infection caused by a brain-eating amoeba after using tap water in a nasal irrigation device, according to the Centers for Disease Control and Prevention. A case report from the agency said the woman died of primary amebic meningoencephalitis, or PAM, a rare but often fatal brain infection caused by the Naegleria fowleri organism. The previously healthy 71-year-old developed severe symptoms, including fever, headache and altered mental status, within four days after using the nasal irrigation device, the case report said. Despite medical treatment for a suspected PAM infection, eight days after the symptoms began, she developed seizures and died. The tap water she used for the sinus rinse came from an RV's water system at a campground in Texas, according to the case report. The CDC recommends the use of distilled, sterile or boiled and cooled tap water for nasal irrigation. PAM is also typically associated with recreational water activities, as the amoeba thrives in warm freshwater lakes, rivers and hot springs. Infections can occur if water containing the ameba goes up the nose and to the brain. To reduce your risk, the CDC suggests holding your nose or wearing a nose clip if you are jumping or diving into fresh water or keeping your head above water in hot springs. In rare cases, people have also become infected from pools and splash pads that did not have enough chlorine, the CDC says. You cannot, however, get a Naegleria fowleri infection from swallowing contaminated water or from someone else who is infected.
Yahoo
an hour ago
- Yahoo
ADPH releases report of first case of West Nile virus of 2025
ALABAMA (WDHN) – Alabama's state department of public health has released their report of the first case of the West Nile Virus of 2025. The report was released, as mosquito season intensifies. The West Nile Virus comes from birds and mosquitos, and symptoms include a headache, nausea and a skin rash. The ADPH said 8 out of 10 infected with the West Nile Virus do not show any symptom, while the outbreak of the virus has become more common. Last year, 34 cases of the West Nile Virus happened in Alabama, according to the CDC. The ADPH reported a case of dengue fever and malaria by residents, who traveled outside of the state as well. To keep away from mosquitos this season, clean and empty items that hold water, cover water containers, keep grass trimmed and use indoor insect spray. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.