DR MAX PEMBERTON: Every day, I see the dreadful impact of cannabis - and it's far worse than anyone can possibly imagine. Let me tell you what will REALLY happen if it's decriminalised
Day in and day out, I see the tragic human fallout from our lackadaisical attitude towards cannabis. I work in a specialist service for people with emerging severe mental illness and most of my patients have experienced psychosis.
The vast majority of them have used cannabis, and their lives have been shattered by this dreadful drug. Around one third of psychosis cases in the capital are the result of cannabis, according to research by Sir Robin Murray, a professor of Psychiatric Research at King's College London.
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The Sun
37 minutes ago
- The Sun
The ‘golden dose' of Mounjaro that experts warn could be deadly – as slimmers rave about it saving money
A GROWING number of slimmers are trying to squeeze extra jabs out of empty Mounjaro pens in a risky bid to cut costs. The weight-loss injections, which can cost hundreds of pounds a month, are designed to deliver a fixed weekly dose. But online users claim there's still a small amount of drug left after the final shot. They say it can be drawn out with a syringe for a bonus jab, dubbed the 'golden dose'. One TikTok user claimed the trick saved her a fortune. By getting five jabs from a four-dose pen, users reckon they can claw back £615 a year. The reports come after NHS England said only a small number of people will be able to get Mounjaro from their GP. It means most people will still have to pay for it privately - which can cost hundreds of pounds a month. 'The drugs are expensive but weight loss is strongly desired, so as a commodity, these drugs are hotly sought-after,' said Professor Naveed Sattar, a cardiologist and obesity expert at the University of Glasgow, said. 'It's no surprise people are going to such extraordinary lengths," she told the inews. Medics say the DIY hack is dangerous and could lead to infection, overdose or death. "People are reading these tips on online forums and being tempted to use them to save money," said Professor Penny Ward, a pharmaceutical expert at King's College London. Women taking fat jabs need 'effective contraception' - as health chiefs warn of serious harm to unborn babies "But they're risking serious side effects from overdosing by doing this - as well as the potential to develop a life-threatening infection. "The potential to develop a life-threatening infection. It's not a good idea at all," she told MailOnline. Talk of the so-called 'golden dose' is also spreading on Reddit weight-loss forums. In one thread with more than 50 comments, a user wrote: "After four pumps of your uk injection pen they tell you to throw it away. "But there is an extra dose or thereabouts in the pen you can self inject with an insulin needle." Another replied saying: "Known much more on here as the fifth dose." 2 Slimmers have also taken to TikTok to rave about the 'discovery'. In one video, a nurse demonstrates how to use a needle to extract leftover medicine from the pen. She wrote: "I do not condone or encourage anybody to take their golden dose this is just what I am doing." Huge risks Professor Penny warned that this practice can be dangerous for "several" reasons. "These injections contain a slight overfill to ensure the full recommended dose is delivered each time," she said. "But by drawing this out with a separate syringe and using it as a so-called fifth dose, you're exposing yourself to serious risk of infection.' Once the pen has been used, it's no longer sterile, meaning any leftover liquid could be contaminated with harmful bacteria. Injecting it could lead to abscesses or, in extreme cases, life-threatening sepsis. There's also the danger of taking too much. 'If you're using your own syringe, it's difficult to measure the correct amount - you may end up taking more than intended,' she warned. Overdosing on the jab can trigger nasty side effects like vomiting and diarrhoea, or in rare cases, pancreatitis - a serious and painful condition that may need hospital treatment. Around one in five cases result in serious complications, with up to 30 per cent proving fatal. The risk rises sharply with higher doses, as the drug can trigger digestive enzymes that begin attacking the pancreas itself. Symptoms include sudden, severe tummy pain, often spreading to the back, along with fever, nausea and a racing heartbeat. "The bigger the dose, the bigger the risk of pancreatitis," Professor Ward warned. Everything you need to know about fat jabs Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases. Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK. Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market. Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year. How do they work? The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight. They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists. They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients' sugar levels are too high. Can I get them? NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics. Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure. GPs generally do not prescribe the drugs for weight loss. Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk. Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health. Are there any risks? Yes – side effects are common but most are relatively mild. Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea. Dr Sarah Jarvis, GP and clinical consultant at said: 'One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.' Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia. Evidence has so far been inconclusive about whether the injections are damaging to patients' mental health. Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines. Mounjaro - dubbed the "King Kong" of weight loss jabs - works by mimicking hormones released by the body when you're full. This makes people feel fuller for longer and therefore less hungry. It appears to be to be more potent than Wegovy - another popular weight loss jab - causing about 20 per cent weight loss after a year's use, compared with Wegovy's 15 per cent. Mounjaro's active ingredient is tirzepatide, a lab-made compound that mimics two gut hormones - GLP-1 and GIP - which help control blood sugar and appetite. This is why it was initially approved to treat diabetes type 2, which happens when people can't control their blood sugar. But in December 2024, it was also cleared for use on the NHS for weight loss in people with a BMI of over 30, or over 27 plus one weight-related condition. 'Excess solution' should be 'discarded' If you notice there is a considerable amount of medication left in your pen after the last dose, Professor Penny added, it may mean that you're not using the injection properly. "Speak to your pharmacist about your technique, or check that you definitely have the right size syringe, as this can impact the amount of medication left over," she said. A spokesperson for Lilly - the drug's manufacturer - said users should not do this, as the remaining liquid may not be a full dose. 'It is important to note that there will be a residual amount of medicine left after the fourth dose," they said. "This does not correspond to a full dose." 'Any excess solution in the pen after use should be discarded.' Dr Alison Cave, chief safety officer of the Medicines and Healthcare products Regulatory Agency, added: "Medicines are approved according to strict dosage guidelines. "Failure to adhere with these guidelines, such as tampering with pre-dosed injection pens, could harm your health or cause personal injury. "People should follow the dosing directions provided by their healthcare provider when prescribed weight-loss medicines and use as directed in the patient information leaflet." What are the other side effects of weight loss jabs? Like any medication, weight loss jabs can have side effects. Common side effects of injections such as Ozempic include: Nausea: This is the most commonly reported side effect, especially when first starting the medication. It often decreases over time as your body adjusts. Vomiting: Can occur, often in conjunction with nausea. Diarrhea: Some people experience gastrointestinal upset. Constipation: Some individuals may also experience constipation. Stomach pain or discomfort: Some people may experience abdominal pain or discomfort. Reduced appetite: This is often a desired effect for people using Ozempic for weight loss. Indigestion: Can cause a feeling of bloating or discomfort after eating. Serious side effects can also include: Pancreatitis: In rare cases, Ozempic may increase the risk of inflammation of the pancreas, known as pancreatitis, which can cause severe stomach pain, nausea, and vomiting. Kidney problems: There have been reports of kidney issues, including kidney failure, though this is uncommon. Thyroid tumors: There's a potential increased risk of thyroid cancer, although this risk is based on animal studies. It is not confirmed in humans, but people with a history of thyroid cancer should avoid Ozempic. Vision problems: Rapid changes in blood sugar levels may affect vision, and some people have reported blurry vision when taking Ozempic. Hypoglycemia (low blood sugar): Especially if used with other medications like sulfonylureas or insulin.
Telegraph
38 minutes ago
- Telegraph
Who owns the news? It must not be a group of foreign powers
Who owns the news? Much of the Left has been obsessed with the issue for over a century. They have long railed against press barons and their supposed bias. So it is perhaps surprising that this Labour Government is taking such a lackadaisical approach to foreign states having substantial holdings in British newspapers. The last Conservative government back in December 2023 intervened to put on hold and scrutinise the proposed sale of The Telegraph to a company backed by Sheikh Mansour, the deputy prime minister of the United Arab Emirates. Columnists, including Charles Moore, The Telegraph's former editor, rightly argued that even if there was no actual interference in the newspaper's editorial line, there would be the perception that the paper would no longer be independent. This would fatally undermine the newspaper's standing by throwing away its reputation for fearless reporting, whatever the reality of the situation. The then government listened and last year, in the Digital, Media and Competitions Act, introduced a new regulatory regime to restrict foreign state ownership of newspapers and news magazines. But this Act only set out the broad principle, not the details of how it would be implemented. A total ban would come with its own problems. There would be little risk of editorial interference if, say, the sovereign wealth fund of Norway was a passive investor owning 3pc or 4pc in a UK-listed media company. During the consultations, it was proposed that a 5pc limit may be appropriate to allow for such holdings. Last month the new Government announced that the threshold would not be 5pc, but actually 15pc. I and many of my colleagues in the House of Lords have serious misgivings about this much higher limit, but it is one we can live with. However, there is another aspect of the draft regulations which is unacceptable. The 15pc threshold is not cumulative, it applies to each individual holding. This means that there would be nothing to stop multiple states each owning 15pc of a newspaper. It has been reported that after The Telegraph's proposed takeover by RedBird Capital, Sheikh Mansour intends to retain up to a 15pc stake in the newspaper. With the current proposals there would be nothing to stop, say, Saudi Arabia, Oman and Bahrain from each taking 15pc holdings. A cumulative 60pc of a British newspaper owned by foreign states is a very different proposition. The guarantees against foreign control would have evaporated. Has this potential scenario arisen as a result of an oversight by Lisa Nandy, the Culture Secretary? Alongside 50 of my fellow peers, I have written to Ms Nandy asking for clarification. Signatories include former chancellor Lord Lamont, former trade secretary Lord Lilley, long-time chairman of the 1922 committee Lord Brady, ex-director of public prosecutions Lord Macdonald and the current chairman of Ipso, the independent press regulator, Lord Faulks. Our fears could be easily assuaged by simply amending the proposed regulations to ensure that 15pc is a cap on total foreign ownership. If the move is deliberate, it raises serious questions about this Government's commitment to a free press. The statutory instrument implementing the Government's regulations has now been laid and will shortly come before both Houses of Parliament. If the proposals reach the Lords in their current form, I and many of my colleagues will not be able to support the measure. The Telegraph's ownership has been left in limbo for two years so far. It is time for the new regulatory framework to be put in place that will allow its smooth transfer to new owners. But this must be done in a way that entrenches the traditional freedoms of our press. The issues are much wider than the future of just one newspaper.
The Sun
38 minutes ago
- The Sun
Mum died trapped head-first between rocks as tide rose after possible delay in scrambling firefighters, inquest told
A MUM died trapped head-first between rocks as the tide rose after a possible delay in sending firefighters, an inquest heard. Saffron Cole-Nottage was walking with her dog and daughter on a path at the base of the sea wall in Lowestoft, Suffolk, when the horror unfolded. 5 The 32-year-old lost her footing, with her head becoming trapped between giant boulders as the tide rose on February 2. Saffron screamed for help as her daughter and passers-by frantically attempted to free the mum-of-three. A pre-inquest review heard Saffron was discovered at 7.45pm and a 999 call was made to the East of England Ambulance Service at 7.52pm. Suffolk Area Coroner Darren Stewart OBE said there appeared to have been contact between the ambulance service and Suffolk Fire and Rescue Service at 8.04pm or 8.05pm. A "subsequent call' from the Coastguard to the fire service but firefighters were not dispatched until five minutes later, the court was told. Mr Stewart said he wanted to examine a possible 'inconsistency' in communications between emergency services. He added: 'In essence I want to understand in terms of the chronology whether there has been correct application of the co-ordination arrangements in respect of the best or most appropriate emergency services response. 'On my initial view of the chronology there seems to be some inconsistency in terms of how some of the responses were being co-ordinated. Whether any of that was causative of her death is another matter that must be considered by the court. 'When it comes to rising water levels and the method of death that occurred which is drowning, there is a very limited window of time available to be able to respond and save a life in those circumstances.' Saffron was eventually rescued by emergency crews but tragically couldn't be saved. A post mortem has been carried out but Saffron's cause of death has not been revealed. Mr Stewart said a full inquest would 'examine the circumstances' of how she became trapped in the rocks and then "sadly dying as a result of the water levels rising". He adjourned the inquest for another pre-inquest hearing in September or October, with a view to a full hearing in March or April next year. It previously emerged Saffron was walking along a path under the town's Esplanade promenade, despite signs telling people to keep away from the area. Local likened the path to an 'ice rink' as it was so slippery due to it being covered in algae. Tributes flooded for Saffron, who lived in Lowestoft with her partner and children after moving from Gillingham, Kent. She had two daughters aged 11 and seven and a baby son born last year. Friend Trish Butler said Saffron was 'a beautiful girl inside and out'. She added: 'She was a lovely girl and a wonderful person, and the life and soul wherever she went.' Flowers left at the scene of the tragedy described her as a 'beautiful' mum who would be 'forever missed'. One touching tribute said: 'My beautiful mummy, I love you the world.' Her partner left a hand-written message, saying: 'My darling Saff, What can I really say. There are no words to express how much we will miss you. 'The world is so cruel and to take you in this freak horrific way will not sit well with me for the rest of my life. 'You will be forever missed by so many, and I'm really not sure I'll ever be the same without you. Me and the kids will love you and never forget you. "Until we meet again, love always, Mike and the kids.' 5 5
