
Alzheimer's research at risk as diagnoses rise
More than 7 million American seniors now live with Alzheimer's disease — the highest number ever recorded, according to 2025 data shared in a new Alzheimer's Association report.
Why it matters: As Alzheimer's diagnoses rise, the federal funding for medical research that's critical to preventing and treating it is at risk of being cut.
State of play: Over 17,300 Californians die from Alzheimer's every year, but addressing cognitive decline early can help stave off the disease.
That's especially important with San Diego County's growing senior population — about 16% of residents.
Zoom in: The odds of being diagnosed with Alzheimer's is higher in San Diego than many other parts of the country, at least in part because of the local hospital system.
That doesn't necessarily mean more people have the disease, but more thorough diagnosing can lead to more cases, better care, new tests and treatments.
Between the lines: UC San Diego has the top NIH-funded neuroscience department in the country, and the university's Alzheimer's Disease Research Center is developing potential treatments, monitoring drug safety and running clinical trials aimed at prevention.
That federal funding is at risk of being pulled, which center director Jim Brewer has said would "absolutely cut the knees out" and could delay progress in addressing the disease, particularly through clinical trials.
The latest: The FDA on Friday cleared the first blood test to help diagnose the disease, which could help with early detection.
By the numbers: About 12% of Californians over 65 are living with Alzheimer's, per 2020 data in the report.
That's almost 720,000 people.
At 15%, Imperial County had the ninth-highest prevalence in the country.
Zoom out: The highest rates of seniors with Alzheimer's are in D.C. (16.8%), Maryland (12.9%) and New York (12.7%), according to the association.
Nearly two-thirds of all Americans diagnosed with the disease are women, per data cited in the report. UCSD researchers are currently trying to figure out why.
Warning signs to watch for in high-risk age groups:
Trouble finding the right word.
Difficulty judging distances.
Misplacing things and struggling to retrace steps.
Be smart: Keeping your brain on its toes, so to speak, can help prevent dementia.
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Yahoo
an hour ago
- Yahoo
Exclusive-Kennedy's new vaccine adviser was expert witness against Merck vaccine
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Newsweek
an hour ago
- Newsweek
AAMC Director on NIH cuts: "Health Will Suffer"
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The government recently cancelled $400 million in federal funding to the university—bringing her 15-year research project to an abrupt halt. Rossetti had been working on the CONCERN Study, which had successfully developed an AI model to detect patient deterioration in the hospital setting. The model could identify risk two days earlier than other models that had attempted to predict bad outcomes; CONCERN differentiated itself by tapping into nurses' practices and detecting patterns of concern in their documentation. The study had been receiving funding from the National Institutes of Health (NIH) for about nine years, and had just published its largest research paper to date in Nature Medicine—demonstrating that throughout a multi-site clinical trial, the AI model had decreased mortality risk by 35 percent, cut sepsis risk by 7.5 percent and shortened length of stay by more than half of a day. Then, on a Monday night in March—at around 10 p.m.—the government email came through, alerting Rossetti's team that their funding was slashed. The email did not give any reasoning or provide clarity on the cuts, Rossetti said. She thought that the word "bias," an important scientific consideration for the evaluation of AI models, may have been confused for a DEI concept and flagged by the Trump administration. "There's really nothing controversial in the work that we're doing, the methods we're using," she told me. Newsweek reached out to the NIH on Wednesday afternoon and will update the web version of this newsletter if we receive a comment. Although the research team is exploring new funding avenues, it won't happen overnight, Rossetti added. It takes a long time to submit one grant proposal, and it took three tries to get the original NIH funding for the CONCERN Study. Leaders fear that they won't be able to sustain their teams in the interim—and not just at Columbia, but at academic medical centers across the country. Yesterday, the Association of American Medical Colleges (AAMC) put out a report addressing the cumulative impact of the federal government's actions on academic medicine. So far in 2025, the administration has terminated 1,183 grants and $2 billion of biomedical research funding from U.S. medical schools and hospitals. It also flagged that 50 percent of medical students' loans could be in jeopardy, and critical services that are often provided by academic medical centers—like burn centers, psychiatric services and trauma centers—could be at risk. "The infrastructure that is required to keep an academic medical center moving forward relies on a partnership with the federal government that is closely linked to research, to medical education and to clinical care," Heather Pierce, Senior Director for Science Policy at the AAMC, told me. "And so as different parts of the mission are impacted, you have to rely on other [parts]. That changes an institution's focus and what they can staff, what they can move forward. All of those specialty areas are potentially at risk." There's no substitute for that partnership, Pierce said (as so many other health care executives and researchers have agreed). I've begun conceptualizing all this as a game of Jenga. Yes, our health care system is historically resilient. Yes, our country's best leaders and brightest minds are at its helm. But there are only so many blocks you can pull before the whole tower tumbles. With each project like Rossetti's that is wriggled from the infrastructure, the foundation becomes increasingly unstable. And with every executive order and every Congressional decision, health care leaders' own moves get more precarious. You can view the full AAMC report here—and read on to the Pulse Check section for more of my interview with Pierce. Essential Reading Hospitals are increasingly standing up digital command centers to improve efficiency and oversight of both in-person and virtual services. In my latest deep dive, I connected with four hospitals to learn how these NASA-esque hubs are improving their operations. Get the scoop here. HHS has removed all 17 members of the Advisory Committee for Immunization Practices , which is responsible for advising the CDC on vaccine safety and protocol. The 17 sitting members were appointed by the Biden administration. In a HHS news release, Secretary Robert F. Kennedy Jr. said the move was "prioritizing the restoration of public trust above any specific pro- or anti-vaccine agenda." , which is responsible for advising the CDC on vaccine safety and protocol. The 17 sitting members were appointed by the Biden administration. In a HHS news release, Secretary Robert F. 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If you're interested in learning more about CHAI's work, I encourage you to watch Newsweek's recent webinar on AI governance, featuring CEO Dr. Brian Anderson. UnitedHealth Group's saga continues as the health care giant considers bids that would allow it to exit from Latin America, Reuters reported on Monday. The company lost more than $8 billion in the market last year and has been trying to leave it since 2022—but the situation has grown more urgent in recent months amid leadership shakeups, criminal probes and public discontent, per two unnamed sources. Pulse Check Heather Pierce is the senior director for science policy at the Association of American Medical Colleges. Heather Pierce is the senior director for science policy at the Association of American Medical Colleges. AAMC Usually, I do a Pulse Check with a CEO in the industry—but this week, I felt that the AAMC's report deserved some extra attention. 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Dinner is usually home-cooked during the week, and we often will eat out on weekends. I call it collecting points during the week and spending them on the weekend. I also avoid eating after 8 p.m. to ensure I give myself the best chances of a restful, full night's sleep. I love my wine but limit alcohol to just one drink a week, even in social settings and while traveling." "I start most days—five or six days a week—with oatmeal. It's become a reliable routine. For lunch during the workweek, I go for salads as much as possible. I tend to eat small portions overall. When I travel and it's difficult to avoid fancy meals, eating small portions is really helpful. Dinner is usually home-cooked during the week, and we often will eat out on weekends. I call it collecting points during the week and spending them on the weekend. I also avoid eating after 8 p.m. to ensure I give myself the best chances of a restful, full night's sleep. 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Mental Health: "I give myself digital silence from Friday evening to Sunday morning—no emails or Slack. Sunday afternoons are for planning, reflection, and deep work. I've followed this practice for over a decade. It started during my consulting days when Monday [to] Thursday were always travel days, so you had to get your ducks in a row on Sunday before you took off on Monday morning. I spend time with my family in the mornings before school, and we eat dinner together most nights. I make sure that Saturdays and Sunday mornings are fully reserved for family and friends. "I give myself digital silence from Friday evening to Sunday morning—no emails or Slack. Sunday afternoons are for planning, reflection, and deep work. I've followed this practice for over a decade. It started during my consulting days when Monday [to] Thursday were always travel days, so you had to get your ducks in a row on Sunday before you took off on Monday morning. 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Newsweek
2 hours ago
- Newsweek
Avocado's New Health Benefit Revealed
Based on facts, either observed and verified firsthand by the reporter, or reported and verified from knowledgeable sources. Newsweek AI is in beta. Translations may contain inaccuracies—please refer to the original content. In news that may have many a millennial lunging for a slice of toast, eating an avocado a day has been linked to better sleep and boosted heart health as a result. Analysis of the largest randomized controlled trial on avocado consumption to date found a link between eating the fruit daily and improved sleep duration, despite the study being designed really to explore the superfood's impact on general health. The study had been supported by the Avocado Nutrition Center and marks the first time avocado intake has been associated with better sleep. "Sleep is emerging as a key lifestyle factor in heart health, and this study invites us to consider how nutrition—and foods like avocado—can play a role in improving it," said paper author and nutritional sciences professor Kristina Petersen of Penn State University in a statement. "Cardiovascular health is influenced by many factors, and while no single food is a silver bullet, some—like avocados—offer a range of nutrients that support multiple aspects of heart health." A stock image of a plate containing avocado on brown bread. A stock image of a plate containing avocado on brown bread. Getty Images Lisa Moskovitz, a registered dietitian and CEO at The NY Nutrition Group, spoke with Newsweek about the findings, giving avocados her seal of approval too. "Avocados are a superfood offering an assortment of heart-healthy nutrients—from cholesterol-lowering monounsaturated fats and fiber to blood pressure-regulating potassium and magnesium," she said. "There is a lot going on in a relatively small package. "I always recommend this Mediterranean staple to my clients as part of a wholesome, healthy and disease-fighting balanced diet." The study involved 969 racially and ethnically diverse American adults, all with elevated waist circumferences—a cardiovascular risk factor that affects nearly 60 percent of U.S. adults. Participants were randomized into two groups: one group consumed one avocado per day while the other had fewer than two avocados per month. Both groups otherwise maintained their usual diets over a six-month period. Although sleep was not the intended focus of the trial, the team's analysis revealed that those in the daily avocado group self-reported longer sleep durations. This finding adds to the growing scientific consensus around the fruit's health-promoting potential. Crucially, it also connects avocado intake to one of the American Heart Association's Life's Essential 8™—a set of key health behaviors and clinical measures that promote optimal cardiovascular health. Alongside sleep, the Essential 8 includes diet quality, physical activity, nicotine exposure, body weight, blood pressure, blood lipids and blood glucose. While the study showed modest reductions in LDL cholesterol and total cholesterol levels, and an increase in overall diet quality measured by the Healthy Eating Index 2015, there were no significant effects on the other Essential 8 components. However, the researchers note that this avenue—avocados and sleep—is ripe for future exploration. Why Do Avocados Improve Sleep? Avocados contain several nutrients that may play a role in sleep regulation. One-third of a medium avocado delivers 13 milligrams of tryptophan, an amino acid precursor to melatonin, the hormone that helps regulate sleep-wake cycles. It also contains 45 micrograms of folate, essential for melatonin production, and 15 milligrams of magnesium, which contributes to muscle relaxation and, as a result, improves sleep quality. Then there is the fruit's signature nutrient profile: 3 grams of fiber—one-third of which is soluble fiber known to reduce cholesterol—and 5 grams of heart-healthy monounsaturated fats, which help lower LDL cholesterol levels and reduce the risk of stroke and heart disease. Do you have a tip on a science story that Newsweek should be covering? Do you have a question about heart health? Let us know via science@ Reference Damani, J. J., Kris‐Etherton, P. M., Lichtenstein, A. H., Matthan, N. R., Sabaté, J., Li, Z., Reboussin, D., & Petersen, K. S. (2025). Effect of Daily Avocado Intake on Cardiovascular Health Assessed by Life's Essential 8: An Ancillary Study of HAT, a Randomized Controlled Trial. Journal of the American Heart Association, 14(5).