
Opinion In a black-and-white world, colour me olo
In 1856, an 18-year-old was trying to find the cure for malaria. Instead, he found a way to create the colour purple. William Henry Perkin, a student at London's Royal College of Chemistry, dipped a piece of cloth into his mixture of coal aniline and chromic acid. The cure for malaria was still about a century away, but what Perkin did discover was a way to create the first colour in synthetic form. Researchers from UC Berkeley and the University of Washington this week made a similar discovery. They had laser pulses fired into their eyes and claimed to have found 'olo', an 'incredibly saturated' blue-green, a colour 'never seen before by the human eye'.
The discovery was made using a device called the Oz Vision System, named after Emerald City in L Frank Baum's The Wonderful Wizard of Oz. The colour cannot be seen by the naked eye without laser stimulation. The scientists used the Oz to stimulate only the M (medium) cone cells in the eye, allowing them to view the colour. It was named 'olo' to denote the binary 010, indicating that of the three cone cells in the eye — L (long), M and S (short) — only one, the M, is stimulated.
Scientists have argued that the discovery will be helpful in better understanding colour blindness and how the human brain visualises colour. But it has also been contested because of its limited value. After all, what is a new colour when only a few people can see it? If not material or scientific value, olo certainly seems to add philosophical value to the understanding of the world. In a world given to viewing the Other in strict binaries of black and white, olo, with its blue-green timbre and contested existence, shows that there is always room for ambiguity. It also comes with a simple lesson: There is value in looking at things through someone else's eyes. You may just discover something new.
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Time of India
29-05-2025
- Time of India
Study reveals six foods that are proven to reverse ageing
Image credits: Getty Images Age reversing is currently the north star of the health industry. Every health or age-conscious person, influencer and brand is working towards the goal in one way or another that they make sure to promote if deemed beneficial. The concept of reverse ageing is related to your biological age, which is the age of the body on a physical and cellular level and not on the basis of the years you have been alive. These two ages- chronological and biological, can be different and the less your biological age is the more healthy your body is and the more lifespan you have. Thus, people are always configuring ways to reduce their biological age and stay healthy. The interest in the concept has led to the popularity of influencers such as Bryan Johnson and Mel Robbins who claim to have perfected the esteemed process. Now, a study published in the Aging journal by researchers from the University of Washington and other institutions has suggested that a diet rich in plant-based foods containing natural substances called methyl adaptogens can potentially slow biological ageing. What foods aid reverse ageing? Image credits: Getty Images The team wanted to investigate how dietary choices influenced DNA methylation, a process that regulates gene activity without affecting the DNA sequence itself. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like 5 Books Warren Buffett Wants You to Read In 2025 Blinkist: Warren Buffett's Reading List Undo The more the DNA methylation in specific sites in the genome, the higher a person's biological age is. In the study, the authors followed 43, healthy middle-aged men from Portland, Oregon who had finished an 8-week program that focused on a plant-based nutrient-rich diet along with exercise, sleep and stress reduction. The results showcased that those who consumed food with more polyphenols which have antioxidants and anti-inflammatory properties helped decrease the biological age by interfering with enzymes involved in DNA methylation. The authors recommended the daily consumption of dark leafy greens, cruciferous vegetables like broccoli, cauliflower, cabbage, colourful vegetables, pumpkin and sunflower seeds, beets, lean meats, low-glycemic fruits like apples, grapefruit and cherries and a serving or more from the methyl adaptogen group. They also suggested avoiding dairy, grains, legumes and alcohol. 6 foods that reverse age The study mentioned six foods that the participants consumed that had powerful impacts on declining their biological age. These include: Berries Image credits: Getty Images A half a cup of berries consumed daily can go a long way in reversing your biological age. According to a study published in the National Library of Medicine, berries contain polyphenolic compounds that lower oxidative stress and inflammation and alter the signalling involved in neuronal communication. This helps prevent age-related deficits in cognitive and motor function. Rosemary Image credits: Getty Images The effects of rosemary on hair health and growth have come to major limelight in recent times with doctors and influencers recommending using the herb in oils and waters to treat damaged hair. Now, researchers recommend consuming half a teaspoon of rosemary every day to aid in reversing biological ageing. In a study published in the National Library of Medicine, it was stated that rosemary extracts increased lifespan extension, and AMPK activation and improved cognitive function. Turmeric Image credits: Getty Images Turmeric is called the golden spice for a reason. The condiment has healing properties which have been known for years. But now, researchers recommend eating half a teaspoon of turmeric daily as the main active substance inside it, curcumin has anti-ageing properties as it changes the levels of proteins involved in the ageing process such as sirtuins and AMPK and inhibits pro-aging proteins such as NF-κB and mTOR, as mentioned in a National Library of Medicine study . Garlic Image credits: Getty Images Eating 2 cloves of garlic daily is said to be beneficial in reverse ageing. The antioxidant properties in the herb help it to prevent cerebral ageing, inhibit platelet aggregation, and improve blood circulation and energy levels, as cited in a study published in the National Library of Medicine. Green Tea Image credits: Getty Images Two cups of green tea daily is advised to be consumed by the study authors. It is able to delay collagen ageing with the help of its antioxidant mechanism. Additionally, it suppresses melanin production too which makes it a popular anti-ageing remedy, as mentioned in the National Library of Medicine. Oolong Tea Image credits: Getty Images If you are one of those rare people who do not like green tea, then study authors recommend swapping it with Oolong tea. You can also drink both. 3 cups of oolong tea daily is advisable to drink. Oolong tea is made from the leaves of the camellia sinensis plant and is partially oxidised. One step to a healthier you—join Times Health+ Yoga and feel the change


Time of India
25-05-2025
- Time of India
#47: Microplastics- The unwanted passenger in our bodies—and what to do about it
Dr. Nickhil Jakatdar has been working at the cutting edge of preventive health and longevity over the last 10 years with the 3 D's – data, doctors, and dietitians – to go from being diagnosed with heart disease at the age of 41, to now having all his blood markers and body measurements in the green and his epigenetic biological age at 41 while his chronological age is 51. With a Ph.D. in Electrical Engineering and Computer Science from UC Berkeley and more than 60 patents to his name, Dr. Jakatdar has always believed in a scientific, data driven and practical approach to solving problems. He has founded or run 5 startups in the areas of semiconductors, consumer mobile video and molecular diagnostics and serves on the Advisory Boards of the South Asian Heart Center in California, the Center for Information Technology Research in the Interest of Society (CITRIS), has been a TEDx speaker and has been the youngest recipient of the esteemed UC Berkeley Distinguished Alumni Award. LESS ... MORE No one knowingly has plastic as part of their meals, but the reality is: we're likely consuming it every day. Not because we're careless, but because modern life is saturated with it—from our food packaging to the clothes we wear, from bottled water to the air in our homes. According to some estimates, the average person ingests between 39,000 and 52,000 plastic particles annually. That's not clickbait—it's from systematic analyses of real food and water samples: seafood, vegetables, protein powders, even salt. And yes, plastic has been found in human lungs, blood, breast milk, placenta, and brain tissue. But the real question is: what does this mean for our long-term health? What are microplastics? Microplastics are plastic fragments less than 5 mm long, often the result of larger items breaking down over time. Nanoplastics are even smaller—less than 1 micrometer—small enough to potentially pass through cell membranes. These particles come from both obvious and hidden sources: Obvious: bottles, wrappers, takeout containers, synthetic fabrics. Hidden: tea bags, detergent pods, skin creams, household dust, tire particles, and synthetic clothing. How do microplastics enter our bodies? The primary route is ingestion—from drinking water, processed foods, and seafood. But exposure also occurs via: Inhalation of household dust, vehicle tire particles, and airborne fibers. Skin contact, possibly, through products like sunscreen and lotion (this is speculative). Once inside, these particles don't just pass through. Studies have found them embedded in lungs, liver, arteries, testes, placenta, and brain tissue. They're not inert either—they interact with our biology. What is the impact of these microplastics on our bodies? We're early in the research curve, but here's what's emerging: Microplastics may trigger inflammation and oxidative stress, key drivers of aging and chronic disease. Chemical additives in plastics—like BPA and phthalates—are well-known endocrine disruptors, altering hormone signaling. In the gut, they may damage the lining and alter the microbiome, affecting immunity and metabolism. A few human studies have added concern: Plastic particles have been found in artery plaque, and those individuals with higher levels of these particles were 4.5 times more likely to experience heart attacks or strokes. Workers in plastic factories show higher rates of cancer, cardiovascular disease, and premature death. Is this definitive proof? No. But early signs that these microplastics may be affecting our bodies make it worth addressing—especially given how easy it is to reduce exposure. What can you do to reduce exposure? You can't eliminate microplastics completely. But like improving your VO₂ max or reducing insulin resistance, small, consistent steps can shift the trajectory. Here's what I am doing to reduce my plastic load in practical ways: 1. Stop Heating Food in Plastic—Always Plastic breaks down faster with heat. Microwaving or boiling food in plastic causes nanoplastics to leach into your food—even in 'microwave-safe' containers. This is what I do: Use glass or ceramic dishes for heating, whether it is leftovers from a restaurant meal that was packed in a plastic container, frozen meals and 'boil-in-bag' rice or vegetables. Avoid pouring hot liquids into plastic bottles, shakers, or cups. Avoid drinking water from plastic bottles as much as possible because I have no idea when those bottles were left in the sun or in heated areas in the supply-chain to bring it to me. Instead, I carry my water in those 1 liter stainless-steel bottles. 2. Filter your water—don't just trust the tap (or the bottle) One study found bottled water may contain 100x more nanoplastics than tap. At home, I have made the following changes around drinking water: I use an activated carbon filter at home because it improves taste, removes chlorine and pesticides, retains healthy minerals, and doesn't waste water—unlike Reverse Osmosis, which strips everything and produces wastewater (waste 2-3 liters of water for every 1 liter of filtered water). 3. Prioritize minimally processed, whole foods Highly processed foods tend to have higher microplastic content due to packaging, handling, and contact with plastic processing surfaces. Here is what we do at our home instead: Buy unpackaged produce when possible. Wash and peel root vegetables thoroughly. Opt for fresh cuts of meat or paneer from the store—avoid items that are breaded, pre-marinated, or vacuum-sealed with additives or preservatives. While I personally don't eat much seafood, I recommend buying seafood only from sources that offer wild-caught options, as farmed fish tend to contain higher levels of microplastics and other contaminants. 4. Upgrade your kitchen tools Chopping vegetables on plastic boards or stirring with plastic utensils can release fragments into your food—especially when heated. A few years ago my wife made the following change Moved to hardwood cutting boards. Switched to stainless steel, copper, ceramic, and wrought iron pots, pans, and utensils. 5. Avoid detergent pods and plastic-coated cleaners Pods are made with polyvinyl alcohol (PVA), which doesn't always fully degrade and contributes to environmental plastic load. So we switched to: Liquid or powder detergent in paper-based boxes. Concentrates or refillable containers that skip single-use packaging. However, there is still plastic packaging involved and we haven't found a great solution to this as yet. Ideas welcome! 6. Watch out for plastics in tea, supplements, and skincare Plastics show up in places you'd never expect; this is what surprised me the most because I wouldn't have imagined the following as sources of microplastics—from tea bags sealed with plastic to coatings on capsules and creams. Here are a few changes we made: On those rare occasions I have green tea, I use loose-leaf tea in a stainless-steel infuser. Choose supplements in softgel or powder form with clean ingredient labels. Since the supplement industry isn't regulated, this is one of the trickier ones to manage. I try to find supplements that follow good manufacturing practices (GMP) standards. However, this usually makes those supplements more expensive. Use mineral-based sunscreens (zinc oxide or titanium dioxide) and plastic-free moisturizers. Final thought: My goal in writing about this topic of reducing microplastic exposure isn't to add to your list of things to worry about, but rather to increase awareness. If you can make even a few of the changes above that are practical and easy for you to put into action, you will reduce your risks that much more. Facebook Twitter Linkedin Email Disclaimer Views expressed above are the author's own.


Hindustan Times
09-05-2025
- Hindustan Times
This new tool measures how fast you're ageing and predicts future health risks: Research
Researchers have created a new "body clock" tool that estimates a person's biological age and may predict the risk of disability or death. Developed by the University of Washington (UW) School of Medicine, the tool analyses eight key metrics from a patient's physical exam and bloodwork. The method called the Health Octo Tool, is explained in a May 5 study published in the journal Nature Communications. (Also read: Doctor reveals '1 thing that's proven to slow ageing' and reduces your biological age ) Researchers say the Health Octo Tool offers a more complete view of wellness than standard health checks, which often focus on single diseases. Using data from large longevity studies, the tool predicts disability, geriatric conditions, physical decline, and mortality. According to Dr. Shabnam Salimi, researchers have developed a method that offers a more comprehensive approach to health than traditional assessments, which focus on individual diseases. The Health Octo Tool predicts disability, geriatric syndrome, physical function, and mortality with 90% accuracy or higher. The tool measures "health entropy," or the molecular and cellular damage accumulated over time, impacting organ function and overall ageing. It assigns a "body organ disease number" based on whether any organs, like the heart or lungs, have been affected by disease. The study showed that organ systems age at different rates, leading to the creation of a Bodily System-Specific Age metric and the Bodily-Specific Clock to reflect each organ's biological age. The researchers introduced the concept of the Body Clock, a comprehensive measure of overall intrinsic age and body age, reflecting the rate at which the body ages. The tool includes components like Speed-Body Clock and Speed-Body Age, which track how biological age impacts walking speed, and Disability-Body Clock and Disability-Body Age, which monitor the effects of ageing on cognitive function and physical disability. Dr. Salimi pointed out that seemingly minor conditions, such as untreated hypertension early in life, could significantly affect ageing later. Treating these conditions early could slow biological ageing. The researchers are working on developing a digital app to help individuals track their biological age, monitor ageing progress, and assess the effects of lifestyle changes like diet, exercise, or longevity-targeting medications. "This app will allow people to visualise how their body and each organ system responds to changes," said Salimi.