Silver Hill Receives Transformational Gift
NEW CANAAN, Conn.--(BUSINESS WIRE)--Silver Hill Hospital, a nationally recognized leader in mental health care for adults and adolescents, is thrilled to announce a $5.5 million gift, the largest contribution in the institution's 94-year history.
This unprecedented gift marks a pivotal moment in the history of Silver Hill, empowering the organization to increase access to its signature, individualized healthcare and ensure clinical excellence advancing its mission to reduce suffering from mental illness and addiction.
The generous contribution was made by a family of past and current volunteers who wish to remain anonymous as they continue their involvement with the hospital. It will enable Silver Hill to further key initiatives through focused program investments, campus infrastructure enhancements, and community and neighborhood programs consistent with a recently adopted strategic plan ensuring accessible, clinical excellence for the future.
In addition to outright support for patient financial aid, patient wellness and employee growth, the contribution supports Silver Hill's long-term financial viability through its endowment.
'This magnificent gift was thoughtfully made by a family who understands Silver Hill's ability to heal and wants to make it accessible to more individuals in need,' said Richard Canning, Silver Hill Board Chair. 'Only half of the 50 million Americans who experience mental illness every year get treatment, and the quality of that treatment can vary wildly. The opportunity to be treated by experienced and empathetic professionals in a healing setting is a gift that we want to make available to as many people as possible.'
The right care at the right time
Silver Hill Hospital's 2025-2030 Strategic Plan recognizes that the rates of mental illness and addiction have risen over the past 50 years. And while there are new and effective treatments available, it is a challenge to connect those in need with the right care at the right time. 'We need institutions that can provide comprehensive treatment at all levels of care, train mental health professionals, conduct research, and advocate for public understanding,' said Andrew J. Gerber, MD, PhD, Silver Hill Hospital President and Medical Director.
'In other areas of medicine, this role has been effectively filled by academic medical centers,' Gerber added. 'However, since the 1990s, these institutions have suffered a dramatic reduction in psychiatric clinical services due to managed care pressures and inadequate insurance reimbursement. As a result, many top clinicians have moved to private practice, making it difficult for the most vulnerable patients to find the care that they need.'
Philanthropy's essential role
As a nonprofit, independent psychiatric hospital, Silver Hill is uniquely positioned to fill the void – providing access to care, sharing best practices through a program of research and education, and advocating for parity in mental health reimbursement. Philanthropy is essential to maintaining excellence, and this gift is a strong expression of support for the leadership and staff and a belief in the signature level of care that has made it one of the nation's top healthcare institutions.
'The donors believe deeply in the importance of high-quality mental health care and in Silver Hill's ability to deliver it,' Gerber said. 'We are extremely grateful for this cornerstone gift and hope it will be a catalyst to inspire further philanthropic investment in our vision of a world free from stigma and isolation where psychiatric care is accessible to all.'
For more information about supporting the Silver Hill mission, please visit www.silverhillhospital.org/give, or contact Tim Dougherty, Chief Advancement Officer at 203.801.2397.
About Silver Hill Hospital
Founded in 1931, Silver Hill Hospital is one of the nation's leading independent, nonprofit psychiatric hospitals dedicated to diagnosing and treating adolescents and adults with a broad range of psychiatric and addiction disorders. Located on an idyllic 44-acre campus in New Canaan, CT, Silver Hill provides inpatient, residential and intensive outpatient treatment with plans tailored to each patient's needs. At Silver Hill, twenty board certified psychiatrists work closely with licensed nurses, social workers, counselors, therapists, and other staff to deliver expert care with commitment and compassion. Through the Silver Hill Academy for Research and Education (SHARE), leading clinicians share best practices through Grand Rounds, blogs, videos, webinars, conferences and publications to reach thousands of practitioners across the country each year. A second location, Silver Hill New York, provides intensive outpatient treatment in the heart of Midtown Manhattan, and is piloting the only data-first mental health and addiction treatment program in the country. For more information, visit silverhillhospital.org and our social media channels.
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QTc Interval Prolongation: QTc interval prolongation can occur, which can increase the risk for ventricular tachyarrhythmias (e.g., torsades de pointes) or sudden death. IBTROZI prolongs the QTc interval in a concentration-dependent manner. In patients who received IBTROZI and underwent at least one post baseline ECG, QTcF increase of >60 msec compared to baseline and QTcF >500 msec occurred in 13% and 2.6% of patients, respectively. 3.4% of patients experienced Grade ≥3. Median time from first dose of IBTROZI to onset of ECG QT prolongation was 22 days (range: 1 day to 38.7 months). Dose interruption and dose reduction each occurred in 2.8% of patients. Significant QTc interval prolongation may occur when IBTROZI is taken with food, strong and moderate CYP3A inhibitors, and/or drugs with a known potential to prolong QTc. Administer IBTROZI on an empty stomach. Avoid concomitant use with strong and moderate CYP3A inhibitors and/or drugs with a known potential to prolong QTc. Hyperuricemia: Hyperuricemia can occur and was reported in 14% of patients, with 16% of these requiring urate-lowering medication without pre-existing gout or hyperuricemia. 0.3% of patients experienced Grade ≥3. Median time to first onset was 2.1 months (range: 7 days to 35.8 months). Dose interruption occurred in 0.3% of patients. Myalgia with Creatine Phosphokinase (CPK) Elevation: Myalgia with or without CPK elevation can occur. Myalgia occurred in 10% of patients. Median time to first onset was 11 days (range: 2 days to 10 months). Concurrent myalgia with increased CPK within a 7-day time period occurred in 0.9% of patients. Dose interruption occurred in 0.3% of patients with myalgia and concurrent CPK elevation. Skeletal Fractures: IBTROZI can increase the risk of fractures. ROS1 inhibitors as a class have been associated with skeletal fractures. 3.4% of patients experienced fractures, including 1.4% Grade 3. Some fractures occurred in the setting of a fall or other predisposing factors. Median time to first onset of fracture was 10.7 months (range: 26 days to 29.1 months). Dose interruption occurred in 0.3% of patients. Embryo-Fetal Toxicity: Based on literature, animal studies, and its mechanism of action, IBTROZI can cause fetal harm when administered to a pregnant woman. ADVERSE REACTIONS Among patients who received IBTROZI, the most frequently reported adverse reactions (≥20%) were diarrhea (64%), nausea (47%), vomiting (43%), dizziness (22%), rash (22%), constipation (21%), and fatigue (20%). The most frequently reported Grade 3/4 laboratory abnormalities (≥5%) were increased ALT (13%), increased AST (10%), decreased neutrophils (5%), and increased creatine phosphokinase (5%). DRUG INTERACTIONS Strong and Moderate CYP3A Inhibitors/CYP3A Inducers and Drugs that Prolong the QTc Interval: Avoid concomitant use. Gastric Acid Reducing Agents: Avoid concomitant use with PPIs and H2 receptor antagonists. If an acid-reducing agent cannot be avoided, administer locally acting antacids at least 2 hours before or 2 hours after taking IBTROZI. OTHER CONSIDERATIONS Pregnancy: Please see important information in Warnings and Precautions under Embryo-Fetal Toxicity. Lactation: Advise women not to breastfeed during treatment and for 3 weeks after the last dose. Effect on Fertility: Based on findings in animals, IBTROZI may impair fertility in males and females. The effects on animal fertility were reversible. Pediatric Use: The safety and effectiveness of IBTROZI in pediatric patients has not been established. Photosensitivity: IBTROZI can cause photosensitivity. Advise patients to minimize sun exposure and to use sun protection, including broad-spectrum sunscreen, during treatment and for at least 5 days after discontinuation. Please see accompanying full Prescribing Information. About Nuvation Bio Nuvation Bio is a global oncology company focused on tackling some of the toughest challenges in cancer treatment by developing therapies that create a profound, positive impact on patients' lives. Our diverse pipeline includes IBTROZI (taletrectinib), a next-generation ROS1 inhibitor; safusidenib, a brain-penetrant IDH1 inhibitor for glioma; NUV-1511, an innovative drug-drug conjugate (DDC) designed for targeted cancer treatment; and NUV-868, a BD2-selective BET inhibitor. Nuvation Bio was founded in 2018 by biopharma industry veteran David Hung, M.D., who previously founded Medivation, Inc., which brought to patients one of the world's leading prostate cancer medicines. Nuvation Bio has offices in New York, San Francisco, Boston, and Shanghai. For more information, visit or follow the company on LinkedIn and X (@nuvationbioinc). Forward-Looking Statements Certain statements included in this press release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements are sometimes accompanied by words such as "believe," "may," "will," "estimate," "continue," "anticipate," "intend," "expect," "should," "would," "plan," "predict," "potential," "seem," "seek," "future," "outlook" and similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, our expectations regarding IBTROZI's therapeutic potential in advanced ROS1+ NSCLC and its potential to become a new standard of care. These statements are based on various assumptions, whether or not identified in this press release, and on the current expectations of the management team of Nuvation Bio and are not predictions of actual performance. These forward-looking statements are subject to a number of risks and uncertainties that may cause actual results to differ from those anticipated by the forward-looking statements, including but not limited to the challenges associated with conducting drug discovery and initiating or conducting clinical studies due to, among other things, difficulties or delays in the regulatory process, enrolling subjects or manufacturing or acquiring necessary products; the emergence or worsening of adverse events or other undesirable side effects; risks associated with preliminary and interim data, which may not be representative of more mature data; and competitive developments. Risks and uncertainties facing Nuvation Bio are described more fully in its Form 10-Q filed with the SEC on May 7, 2025 under the heading "Risk Factors," and other documents that Nuvation Bio has filed or will file with the SEC. You are cautioned not to place undue reliance on the forward-looking statements, which speak only as of the date of this press release. Nuvation Bio disclaims any obligation or undertaking to update, supplement or revise any forward-looking statements contained in this press release. View source version on Contacts Media and Investor ContactsNuvation Bio Investor Contact ir@ Nuvation Bio Media Contact media@ Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
