
Signs of Terry Pratchett's dementia hidden in his novels
Scientists reading between the lines of Terry Pratchett's novels believe they have spotted early signs of the author's dementia years before he was diagnosed. A study of 33 of Pratchett's Discworld books found he used simpler language in his later works, which can be a sign of dementia. The British fantasy writer, who died 10 years ago this week, revealed in 2007 that he had a rare form of Alzheimer's disease. The latest research suggests signs of linguistic decline were evident as early as 1998's The Last Continent. As time went on, Pratchett used less varied nouns, verbs and adjectives in his work, researchers told the New Scientist, despite an increase in the overall word count of his books. "This demonstrates a long preclinical period of dementia and the subtle impairments that aren't necessarily picked up by traditional cognitive tests," Loughborough University researcher Thom Wilcockson told the magazine. Pratchett had a form of the disease called posterior cortical atrophy, which damages the rear of the brain. People living with it tend to have problems with their vision and may struggle with words and numbers, the UK's Alzheimer's Society says. It says the first symptoms tend to occur when people are in their 50s or 60s, but early signs are "often subtle" and do not immediately prompt a diagnosis. Pratchett was 59 when he was diagnosed, saying he could no longer type and had given up his driving licence. He continued writing and his 41st and final Discworld book, The Shepherd's Crown, was published in 2015, six months after his death at the age of 66. He also donated money to Alzheimer's research in the hope a cure would be found before he died. Marking the anniversary of his death, Pratchett's former assistant Rob Wilkins said the author "indisputably lives on" in the minds of his readers. "While his words live on, so does Terry, and that will be the case, no question, not just for this one decade so quickly gone but for many further decades to come, "he said. Agatha Christie's detective novels have similarly been put under the microscope in the past, by researchers in Canada who suggested she too might have had Alzheimer's. They said the breadth of her vocabulary appeared to have dropped by 15 to 30 per cent towards the end of her life, with more repeated phrases in her work. Researchers found similar trends in the work of the 20th-century novelist Iris Murdoch, who was known to have Alzheimer's when she died in 1999. Her final novel, Jackson's Dilemma, was measured as using the simplest language of all her works.
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Middle East Eye
7 days ago
- Middle East Eye
Alaa Abd el-Fattah's mother at risk of ‘sudden death', doctor says
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Arabian Post
29-05-2025
- Arabian Post
Humansa and i-Cognitio Sciences Unveil the World's First AI-Powered Retinal Imaging for Alzheimer's Risk Detection
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(From left to right: Dr. Sanja Tomovska, member of the Humansa International Advisory Committee; Ms. Elaine Jiang, Founding Partner of Humansa; Professor Vincent Mok Chung-tong, Mok Hing Yiu Professor of Medicine of CUHK; Mr. Vincent Wong, Chief Commercial & Applied AI Officer of Humansa; Ms. Charmaine So, Wellness Coach at Humansa; Mr. Don So, CEO of Humansa.) The Humansa BrainSpark Program is a timely response to the alarming statistics in developed Asia-Pacific regions, where the mean life expectancy has reached 85 years. Yet, 1 in 3 individuals aged 85 or above may suffer from dementia, a devastating disease that robs individuals of their independence and quality of life. Research shows that 45% of dementia cases can be prevented or delayed by optimizing modifiable risk factors, making early detection and personalized interventions critical. ADVERTISEMENT A Revolutionary Approach to Brain Health The Humansa BrainSpark Program embodies a proactive approach to brain health by offering: Comprehensive Brain Health Assessment: Powered by state-of-the-art AI retinal imaging technology (i-Cog Brain Health) led and developed by Prof. Vincent Mok's team, the program evaluates brain health and identifies early signals of Alzheimer's disease. The AI model, developed and validated using nearly 13,000 fundus photographs from 648 Alzheimer's patients and 3,240 cognitively normal subjects, demonstrated accuracies ranging from 80% to 92% among various datasets of multi-ethnicities and multi-countries. The study was led by CUHK in collaboration with Universities in Singapore (National University of Singapore, Duke-National University, Nanyang Technological University), China (Tsinghua University), US (Mayo Clinic) and UK (Queen's University Belfast). The findings were published in the prestigious Lancet Digital Health journal in 2022. Tailor-Made Lifestyle Solutions: The Humansa BrainSpark Program offers tailor-made solutions that go beyond standard care, focusing on early detection and prevention of major chronic diseases, including Alzheimer's and dementia. By combining advanced AI technology with personalized care, Humansa provides lifestyle interventions, medical support, and preventive strategies tailored to each individual's unique risk profile. Additionally, Humansa's signature membership program offers a holistic anti-aging solution. This comprehensive package includes personalized recommendations on supplements, the frequency of restorative therapies, and other longevity strategies, empowering individuals to take proactive steps toward better brain health and overall well-being. Professor Vincent Mok, Founding Director of i-Cognitio Sciences and Mok Hing Yiu Professor of Medicine of CUHK explains, 'The retina is an extension of the brain, and through non-invasive fundus photography, we can detect changes in the blood vessels and nerves of the retina that are associated with Alzheimer's disease. These changes can appear 10–15 years before symptoms develop, giving us a critical window for early intervention. This AI model can identify early microvascular changes associated with Alzheimer's disease that may not be detected even by conventional MRI, making it a powerful tool for identifying high-risk cases in both clinical and community settings.' ADVERTISEMENT Regarding the Humansa BrainSpark Program, Professor Mok adds, 'This program is an innovative initiative that combines cutting-edge AI technology with personalized care approach. It encourages individuals to take proactive steps to protect their brain health, enabling early preventive treatments and lifestyle changes that can slow cognitive decline and preserve quality of life.' Aligning with Humansa's Methodology to Longevity The newly launched Humansa BrainSpark Program is a cornerstone of Humansa's methodology to longevity and its signature Future Health Program, which emphasizes prevention, early detection, and personalized care. Cognitive function is a critical pillar of Humansa's longevity strategy, as maintaining brain health is essential for living a long, independent, and fulfilling life. Don So, CEO of Humansa, shares, 'At Humansa, we believe that aging is not a passive process—it's a skill, a choice, and a science. Cognitive function is at the heart of our longevity strategy because it directly impacts an individual's ability to live independently and enjoy life to the fullest. The symptoms may show up decades later, but the seeds are often planted much earlier. The silent inflammation, the unchecked insulin resistance, and the daily choices—small and seemingly insignificant—that quietly shape your destiny. The Brain Health Program is a testament to our commitment to empowering individuals to live longer, healthier lives by providing them with the tools and knowledge to protect their brain health.' A Call to Action The Humansa BrainSpark Program combines cutting-edge technology with personalized care, offering individuals a proactive way to protect their brain health and live longer, healthier lives. For more information or to schedule an assessment, please visit Hashtag: #Humansa The issuer is solely responsible for the content of this announcement. About Humansa Founded in 2020, Humansa is a pioneering health and wellness brand dedicated to empowering individuals to extend their healthspan and live life to the fullest. Headquartered in Hong Kong, Humansa operates over 40 centers and partners with a trusted network across the world. By integrating cutting-edge science with personalized care, Humansa is redefining the future of health and longevity. Our offerings span proactive health assessments, evidence-based treatments, and continuous health optimization, setting a new standard in preventive and precision health. Explore more at: About i-Cognitio Sciences i-Cognitio Sciences is a spin-off medical technology company from CUHK, specializing in AI-driven ocular imaging technologies for brain health evaluation.


Emirates Woman
27-05-2025
- Emirates Woman
7 editor-approved facials to book in Dubai
With a myriad of facials including microdermabrasion, laser facial, hydrafacials and more, finding the right facial for you in the most important task. Dubai offers a wide range of facial treatments catering to all skin types and concerns, from luxurious spa experiences to advanced dermatological procedures. Popular options include HydraFacial for deep hydration and cleansing, chemical peels for skin resurfacing, and oxygen facials for instant glow and rejuvenation. Clinics like Facette Facial Bar provide personalised treatments, while high-end resorts such as Atlantis The Royal and One&Only The Palm offer indulgent experiences in stunning settings. Whether you're looking for anti-ageing solutions, acne treatment, or a pre-event glow, Dubai's facials combine innovation with luxury for visibly refreshed skin. To narrow it down, Emirates Woman has created a guide of all must-try facials for glowing skin. Facette Facial Bar Facette Facial Bar has just opened its second branch in Jumeirah Al Wasl. The Fire & Ice Facial clinical treatment and Red Carpet favorite by iS Clinical is designed to rapidly and safely resurface the skin, diminishing the appearance of fine lines and wrinkles while smoothing, softening, and encouraging overall skin rejuvenation. Excellent for all skin types and ages, this facial results in a complexion that is dramatically refined, with no downtime, peeling, or other negative side effects. It takes place for 60 minutes and is priced at Dhs787.50. For more information visit Skin Laundry Known for their laser facials, Skin Laundry has garnered a name for themselves in Dubai. With just 15 minutes and zero downtime, lasers have been made a thing with Skin Laundry. The Power Fractional Facial is a high-intensity laser for visible results. This 30-minute powerhouse facial uses fractional laser technology to treat deeper skin concerns with faster results. It stimulates collagen, improves texture, and reduces pigmentation with 1–3 days of light downtime. For more information visit Sisters Beauty Lounge Known for extravagant beauty list, experience the ultimate in British skincare with the SISTERS X Elemis Pro-Collagen Facial, a luxury anti-aging treatment designed to deeply hydrate, firm, and restore your skin's youthful glow. Powered by the award-winning Pro-Collagen range, this facial delivers clinically proven results, smoothing fine lines while boosting elasticity and radiance. Whether you choose the 60-minute glow-boosting treatment or indulge in the 90-minute version with deep extraction and a relaxing massage, this is skincare at its most indulgent. Prices for this start at Dhs700. It's available at the various locations in Dubai including Dubai Mall, Mall of The Emirates, The Village Mall, City Center Mirdif, City Walk and JBR. For more information visit Heleo4® Heleo4® is a non-invasive cosmetic and aesthetic procedure aimed at cellular rejuvenation and improvement of the skin's natural resources . The innovative concept is a perfect standalone skin revitalization procedure as well as a preparatory step before any cosmetic treatments for maximum effectiveness and the best long-lasting results . The uniqueness lies in its innovative approach targeting processes that stimulate the division of healthy and young cells. The facial is available at various clinics in Dubai ranging from Evolution Clinic, Milyne Esthetic Clinic and more. For more information visit Blended Wellness View this post on Instagram A post shared by Blended (@blendedwellnessdxb) Experience a revitalising treatment designed to boost lymphatic circulation and support your body's natural detoxification. Using gentle, rhythmic movements and detoxifying essential oils, this massage helps reduce water retention, ease heaviness, and restore a sense of lightness. Perfect for renewing your energy, it leaves you feeling refreshed, balanced, and in harmony with your body. The Detox and Flow facial for 60 minutes is priced at Dhs650 for 60 minutes at Blended Wellness' latest branch in Dubai Marina. For more information visit Orskin Aesthetics As one of the most transformative facials on the market right now – the DMK Enzyme Facial is a must-try. This treatment works by oxygenating the skin through reverse osmosis, detoxifying at a cellular level and leaving the complexion visibly firmer, smoother and more radiant. Designed to restore your skin's natural vitality, it combines advanced enzyme therapy with rejuvenating techniques to deliver visible, long-lasting results. For more information visit – For more on luxury lifestyle, news, fashion and beauty follow Emirates Woman on Facebook and Instagram Images: Supplied Feature Image: