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What we do (and don't) know about tinnitus

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UK medicine regulator warns that women taking Mounjaro, Ozempic need to use effective contraception
UK medicine regulator warns that women taking Mounjaro, Ozempic need to use effective contraception

ABC News

time2 hours ago

  • ABC News

UK medicine regulator warns that women taking Mounjaro, Ozempic need to use effective contraception

Women in the UK have been urged to use effective contraception if they are using weight loss drugs after dozens of reports of unintentional pregnancies from people taking the medication. The Medicines and Healthcare products Regulatory Agency (MHRA) warning said women taking popular "skinny jabs" like Ozempic, Mounjaro and Wegovy should "use a barrier form of contraception and do not rely on oral contraception." The warning comes after the agency received 40 reports relating to unintended pregnancies while using such weight loss drugs. Ying Cheong, a consultant in reproductive medicine at the University of Southampton, called the MHRA's advice "both timely and necessary". "Gastrointestinal side-effects such as vomiting and diarrhoea can impair oral contraceptive absorption, increasing the risk of unintended pregnancy," she said. The warning from the MHRA urged women to use "effective contraception while taking these medicines and, in some cases, for up to two months between stopping the medicine and trying to get pregnant." It also made clear that these drugs "must not be taken during pregnancy, while trying to get pregnant, or during breastfeeding." "Anyone who gets pregnant while using them should speak to their healthcare professional and stop the medicine as soon as possible… because there is not enough safety data to know whether taking the medicine could cause harm to the baby," it added. Dr Alison Cave, MHRA Chief Safety Officer said "skinny jabs are medicines licensed to treat specific medical conditions and should not be used as aesthetic or cosmetic treatments." Rebecca Reynolds, a professor of metabolic medicine at the University of Edinburgh, said there was "hardly any available data from human studies" to know if the weight loss drugs were safe in pregnancy. "The data from animal studies suggests the potential for harm with low birth-weight and skeletal abnormalities, though more evidence is needed to assess if there are risks of taking these drugs in humans," she added. The MHRA also warned about the impact of another weight-loss and diabetes injection, Mounjaro, on the effectiveness of oral contraception for people who are overweight. "Those taking Mounjaro who are overweight and are using an oral form of contraception are advised to also use a non-oral form of contraception," it said. The MHRA also added a reminder to people that these medicines "should not be bought from unregulated sellers such as beauty salons or via social media", or taken without a a prescription from a doctor. "Not only does this expose people wanting to lose weight to serious health risks, it is also against the law to sell these medicines in this way," the statement said. ABC/AFP

‘Ashamed': TV reporter claims Sean ‘Diddy' Combs drugged and raped her on a tour bus
‘Ashamed': TV reporter claims Sean ‘Diddy' Combs drugged and raped her on a tour bus

News.com.au

time7 hours ago

  • News.com.au

‘Ashamed': TV reporter claims Sean ‘Diddy' Combs drugged and raped her on a tour bus

A reporter has accused Sean 'Diddy' Combs of drugging and raping her after she tried to get an interview in the midst of his sex trafficking trial. Kathi Steininger claimed she was set to tell her dark story on the stand, but broke her anonymity after she was dismissed, The US Sun reported. Combs, 55, is accused of hiring prostitutes as perverse entertainment for his so-called 'freak offs,' which were sex parties that had a roster of high-profile guests. He would allegedly ply attendees and sex workers with drugs before filming them in compromising positions, and use the tapes as blackmail. At the centre of the charges is his relationship with ex-girlfriend Cassie Ventura, who broke the story wide open when she sued the mega producer in November 2023. In that suit, she accused her ex-lover of raping and beating her, as well as forcing her to take part in the sometimes days-long freak-offs. After the lawsuit was filed and settled out of court, dozens of alleged victims came forward with legal complaints of their own, where they described harrowing brushes with the rapper. Now, Steininger, who is an Austrian national, has claimed in an interview that she was also targeted by the mega producer when she was just 19 years old. In March 2000, the budding journalist scored an on-camera interview with Combs during his European tour, she told Austrian broadcaster PULS 24 on Monday. But at some point during the chat, she claims she was separated from her cameraman and given a drink by Combs, which she believes was drugged. The next thing she knew, the then-teenager was allegedly on the back of a tour bus being raped by the musician. She said she felt too out of it to move or cry for help. 'There was 100 percent something in it,' she said of the drink. 'I would never have gone to bed with that man.' After the alleged attack, she said she felt too 'ashamed' to tell anyone. Steininger claimed she was going to take the stand as part of Combs' ongoing trial, but said her story was out of the statute of limitations because she and Diddy were overseas. After getting that news, she chose to break her anonymity and join the growing chorus of women and men urging for justice. The accuser claimed the alleged attack left her with post-traumatic stress disorder and that she was unable to work. She's reached out to prosecutors in Austria to pursue charges, but because the alleged attack was so long ago, it's also considered outside the statute of limitations. However, she claims that state attorneys told her they would re-examine the case based on the results of Combs' sex trafficking trial. 'I want some kind of punishment for what he did to me,' she said. The US Sun has reached out to Combs' spokesperson for comment.

‘Zero deaths': new tech to change cars forever
‘Zero deaths': new tech to change cars forever

News.com.au

time8 hours ago

  • News.com.au

‘Zero deaths': new tech to change cars forever

Some 66 years and a more than million lives saved since engineer Volvo's Nils Bohlin invented the three-point safety belt, the Swedish brand has once again reinvented the humble seat belt with an adaptive restraint system that adjusts to your body shape to lower risk of injury. Primed to be introduced on next-year's mid-size all-electric Volvo EX60 SUV, the next-gen multi-adaptive belt was developed following real-world accidents saw a higher risk of injury for those unfortunates among us not built like mister or misses average. Painstakingly analysing data from over 80,000 people involved in real-life accidents globally over the last five decades, Volvo found that tall occupants were particularly exposed to head injuries, while smaller drivers and passengers were prone to painful fractured ribs. A rethink was needed, that prompted Volvo engineers to introduce an advanced adaptive safety belt. This belt tailors its responses to those onboard to minimise injury following an impact and the clever pioneering tech works even before you've placed your bum on seat. SNEAKY SAFETY Sneakily using a combination of interior and exterior sensors, the Volvo accurately sizes you up by measuring your height, weight, body shape and then takes account of your seating position and posture. While modern safety belts already use load limiters to control forces applied on the human body, the new tech broadens the profile of responses from three- to a Spinal Tap-sounding 11, matching each setting to the individual on board. The belts are now so clever that they even act differently depending on the direction or speed of the vehicle. The result is a restraint system that dishes out higher belt loads for larger occupants that reduces the chance of a head injury, while lighter passengers receive lower belt loads to slash the risk of painful cracked ribs. It's not just weight or height Volvo boffins have catered to. A broad spectrum of load-limiting profiles for whatever shape you are, even includes the heavily pregnant and (thanks to nifty over-the-air software updates) the tech will only get more sophisticated as it matures. Forever at the forefront of safety, the beauty of the original three-point safety belt was not just how effective it was in the Volvo Amazon sedan back in 1959 but how the Swede firm effectively gave the patent away for free, with neither its inventor nor carmaker earning a cent from its use in other brands. DEMOCRATISATION OF SAFETY Further innovations over the years that have democratised safety include the rear-facing child seat (1972), that mimicked how astronauts were positioned for takeoff, the booster cushion (1978) that literally boosted comfort and safety for seat-belt-wearing kids and advanced driver assist tech that includes blind-spot detection (2003) and an early collision avoiding form of autonomous emergency braking that dates back to 2008. Volvo declared that it remains committed to its goal that by 2030 it aims to prevent any fatal or serious injury in its cars, with the ultimate aim of no collision in any of its vehicles. While the world's first mandatory seat belt laws were introduced back in 1970 in Victoria, the rest of the world was much slower to recognise the benefits of the lifesaving tech. In the United States, even up until the mid-1980s, seat belt laws triggered protests over claims they violated civil rights. Today, only the small state of New Hampshire does not require occupants to wear seat belts while driving a vehicle.

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