AIIMS Bhopal detects dominance of new XFG Covid variant, finds no trace of Nimbus strain
Bhopal: AIIMS Bhopal is reporting 'no detection' of NB.1 (Nimbus variant) in their sequenced samples from Madhya Pradesh, despite its classification as a 'Variant Under Monitoring' by the WHO.
AIIMS Bhopal's data shows the early dominance of XFG in MP, while NB.1.8.1 is more prominent in other regions like Delhi, Maharashtra, and Kerala.
Regional Virology Laboratory at AIIMS Bhopal completed sequencing of 44 Covid-19 positive samples collected between May and June 2025. The samples originated from Bhopal (14), Gwalior (22), Tikamgarh (2), and Indore, Khargon, Chhindwara, Lalitpur, Sidhi, and Gaya (one each).
Analysis showed XFG variant as the dominant strain, present in 28 of 44 samples (63.6%). This variant, which developed from the LF.7 variant, was initially identified in May 2025, increased through early June, and became exclusive by late June.
XFG.3, a new sub-variant evolved from XFG lineage, appeared in 5 of the 28 XFG-positive samples. The LF.7 variant, which represented 50% of samples in May, gradually decreased until its complete absence by late June.
Both XFG and LF.7 variants can affect vaccinated individuals but have only caused mild or asymptomatic infections. The WHO has not categorised them as 'Variants of Concern' or 'Variants Under Monitoring.
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AIIMS Bhopal director Dr Ajai Singh said, "AIIMS Bhopal Regional Virology Laboratory is working with scientific rigor to ensure that no emerging viral variant goes undetected. The early detection of variants like XFG and its sub-lineages helps us understand the virus's behavior and take timely precautionary public health measures."
Regular genomic sequencing serves as an essential component of epidemic preparedness and response. AIIMS Bhopal advocates for consistent genomic surveillance of SARS-CoV-2 as a crucial public health activity in Madhya Pradesh and adjacent regions.
This surveillance strategy enables early detection, prompt intervention, and improved readiness against potential future Covid-19 outbreaks or emerging variants.
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