Roche's Tecentriq With Lurbinectedin Increases Survival to Small-Cell Lung Cancer, Study Says
Roche said Tecentriq combined with lurbinectedin shows significant survival benefits for patients with extensive-stage small cell lung cancer.
The Swiss pharmaceutical company said Tuesday that late-stage trials showed the combination led to a 46% reduction in the risk of the disease progressing or death, and 27% reduction in the risk of death.
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Health Line
an hour ago
- Health Line
Does Drinking Olive Oil Have Any Benefits?
Some people report that drinking olive oil may help clear your system of toxins, ease indigestion, and help you lose weight. However, more research is needed. Olive oil is widely recognized for its health benefits. It boasts anti-inflammatory and antioxidant properties and may help protect against certain chronic diseases. While it's commonly used as a cooking and dipping oil, some people believe that drinking it will allow you to reap its maximum benefits. Why do some people drink olive oil? Some people report drinking olive oil to detox, soothe their stomachs, and for other health benefits, believing that it provides even more benefits than cooking with it or using it on a salad. While there's research suggesting many health benefits of consuming olive oil, there's no research to support the advantages of drinking olive oil over consuming it any other way. More research is needed to determine if there are advantages to drinking your olive oil. What are the potential benefits of drinking olive oil? Studies suggest that drinking olive oil may offer several health benefits. It may help meet the recommended intake of healthy fats Most people eat enough total fat, but many fall short of getting enough polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA), which are found in certain oils, nuts, seeds, and other plant sources. Dietary guidelines recommend that you get no more than 30% of your calories from fat, with less than 10% of those calories from saturated fat. In their 2020-2025 Dietary Guidelines, the World Health Organization (WHO) recommends that people 2 years and older substitute MUFAs and PUFAs for saturated and trans fats. Olive oil is one of the richest plant sources of MUFAs, and consuming it can help you meet your needs of this type of fat. MUFAs are especially beneficial for heart health and may help reduce your risk of heart disease. MUFAs are found in some animal products, but studies suggest their greatest health benefits are achieved by eating plant-based sources of this fat. If you consume insufficient amounts of this fat in your diet, drinking a couple of tablespoons of olive oil daily could help you meet the recommended amount. May relieve constipation Drinking olive oil may relieve constipation, which affects approximately 25% of adults over the age of 60. One 4-week study from 2014 found that giving about 1 teaspoon (4 ml) of olive oil daily to 50 constipated hemodialysis patients reported it significantly softened their stools. Furthermore, consuming olive oil was found to be as effective as mineral oil — a commonly used stool softener — at relieving constipation. More research is needed to understand how drinking olive oil may help relieve constipation. May benefit heart health Olive oil has long been acknowledged as a heart-healthy fat. One compound thought to play a role in supporting heart health is oleic acid, a type of monounsaturated fat found in high quantities in olive oil. When used in place of other fat sources, oleic acid may reduce the risk of heart disease. The Food and Drug Administration (FDA) suggests that replacing fats and oils high in saturated fat with 1.5 tablespoons (22 ml) of oils high in oleic acid daily may reduce your risk of heart disease. To achieve this benefit, it's important to avoid increasing the total calories you eat per day if possible when adding oleic acid to your diet. A 2019 study of 7,447 people who were at high risk of developing cardiovascular disease but didn't have it yet. The study compared participants who followed a Mediterranean diet and consumed at least four tablespoons (60 ml) of olive oil daily, individuals who followed a Mediterranean diet and ate nuts, or individuals who followed a low fat diet for 5 years. Researchers found a lower hazard ratio – a measure of relative risk, in this study, the risk was having a cardiac event – among the group who consumed olive oil than the other two groups. Other studies have found that people who consume a high amount of olive oil may have a reduced risk of heart disease. While there's no shortage of studies on olive oil and heart disease, more research is needed to support the theory that drinking olive oil may improve heart health. Other benefits In addition to the benefits above, drinking olive oil may have the following effects: Help manage blood sugar: A 2023 study found that olive oil, especially extra virgin, is effective for glycaemic control in individuals with type 2 diabetes. Support bone health: A study of 523 women found that consuming over 18 grams (20 ml) of olive oil daily resulted in significantly higher bone density compared with consuming less than that amount daily. Reduce inflammation: Olive oil may contain several compounds with anti-inflammatory effects, including oleocanthal. Limitations While drinking olive oil may offer several potential health benefits, there are downsides to consider. High in calories and may cause weight gain Olive oil is high in calories, containing 119 per tablespoon (13.5 g). Although the relationship between calorie intake and weight gain is complicated and depends on many factors, it's well established that consuming more calories than you burn contributes to weight gain. Research suggests that increased MUFA intake also increases body weight, suggesting that olive oil could contribute to weight gain if consumed in excess. For this reason, it's important to be aware of your calorie intake, regardless of the source of calories. Other considerations It's important to consider the following when considering drinking olive oil: Provides more benefits when consumed with food: For example, consuming olive oil with tomato products significantly increases the absorption of disease-fighting antioxidants in tomatoes. Can displace healthy foods: Although olive oil is a healthy fat source, it's less nutritious than whole foods. Drinking too much may displace healthier foods, such as other healthy fats, vegetables, and proteins. Potential allergen: Although rare, olive pollen is a potential allergen, and olive oil can cause contact dermatitis in affected individuals. Many benefits are not supported by research: Many of the purported benefits of drinking olive oil are not supported by research but instead endorsed by companies selling olive oil or personal anecdotes. Should you drink olive oil? Olive oil can be part of a healthy diet, affording many health benefits. However, it's unclear whether drinking large amounts of olive oil would provide benefits beyond those associated with the recommended intake. Many studies have documented the benefits of following a diet rich in olive oil, but research supporting the consumption of this oil is limited. Additionally, drinking too much olive oil can displace healthy foods in your diet and may cause you to exceed the recommendations for daily fat or calorie intake.
Forbes
2 hours ago
- Forbes
The 10 Best Body Oils That Provide Long-Lasting Hydration
Body oils are the unsung hydrating heroes of skincare. They offer many of the same benefits of a body lotion, but they're better at creating a barrier to lock in moisture. The best body oils are lightweight, hydrating and nourishing, without a heavy, greasy feel, like our top pick, L'Occitane's Almond Supple Skin Body Oil, and our drugstore favorite, Shea Moisture's Coconut and Hibiscus Body Oil. The best body oils nourish and hydrate without feeling greasy—and can offer additional skin ... More benefits. Body oils deliver radiance-boosting antioxidants and over time can help strengthen the skin barrier. When shopping for the right one, look for superstar ingredients such as squalane, vitamin E and hyaluronic acid for deep, lasting hydration without irritation. After consulting with deputy editor Jane Sung and massage therapist Matthew Perry, we've rounded up all the best body oils that soften and nourish. Amazon Size: 3.3 ounces | Key ingredients: Almond oil, sunflower seed oil, vitamin E | Price per fluid ounce: $16.06Best for: Skip if: L'Occitane's body oil consistently receives top marks for its velvety feel and satin finish. It's made with 50% almond oil that hydrates, softens and makes skin supple, so it's a great post-shower add-on for bare skin-season. One reviewer says it 'makes you look like you're glowing,' and many rave about the fresh almond and warm vanilla scent. Ulta Beauty Size: 8.0 ounces | Key ingredients: Coconut oil, shea butter, hibiscus flower | Price per fluid ounce: $1.62 Best for: Skip if: This body oil is very affordable and multi-purpose: It can be used as a post-shower skin hydrator, massage oil or luxurious spa bath addition. The texture is not sticky, and it doesn't leave a heavy feel, but instead if absorbs well into skin rather than sitting on top. Reviewers love that this tropical-smelling oil glides on smoothly and doesn't leave a greasy residue like some other options. Nordstrom Size: 5.1 ounces | Key ingredients: Vitamin E, vitamin C, ceramides | Price per fluid ounce: $47.06 Best for: Skip if: Retrouvé's formula is rich and concentrated. It's packed with ingredients like vitamin E, vitamin C, avocado oil, jojoba seed oil and bakuchiol, which work together to reinvigorate dull skin and address the visible signs of aging. In addition to its intense moisturizing properties, it treats fine lines and wrinkles, evens tone, and makes skin glowy, so you'll want to show off skin rather than cover it up. Amazon Size: 4 ounces | Key ingredients: Jojoba oil, coconut oil, argan oil, castor oil, vitamin B, vitamin E | Price per fluid ounce: $8.75 Best for: Skip if: Maude's cold-pressed oil is a hybrid moisturizer, massage oil and after-shower treatment. This formula is rich in fatty acids that soften, moisturize and soothe. It's fragrance free, too, so the scent won't clash with any lotion or perfume, and it's not irritating on sensitive skin. Reviewers note that a little goes a long way with this one. Nordstrom Size: 2 ounces | Key ingredients: Jojoba oil, coconut oil, sunflower oil | Price per fluid ounce: $24 Best for: Skip if: While this is often used as a pre-wash hair and scalp oil, it's also a non-greasy hydrator that can transform dry skin from flaky and parched to soft and supple. It's comprised of six botanical oils—including jojoba, coconut and macadamia nut—that are ultra-nourishing to prevent itchy, cracked skin. Sung uses it regularly and likes the pleasant scent, with notes of bergamot, vetiver and neroli, and how it's not overpowering either. Amazon Size: 5 ounces | Key ingredients: Undaria seaweed, white lupin, botanical oils | Price per fluid ounce: $10.40 Best for: Skip if: Finding a body oil with a smell that is not overbearing or excessively sweet can be a challenge, but Osea's formula's scent—with notes of mango, mandarin, grapefruit, lime and cypress—is light and uplifting. Another favorite of Sung's, this oil is made with algae that gives skin benefits, too. It relieves dry skin and leaves a nice glow without a slippery feel, and it boosts skin elasticity and crepiness for a more youthful appearance. Amazon Size: 4.2 ounces | Key ingredients: Vitamin E, vitamin A, rosemary oil, chamomile oil | Price per fluid ounce: $5.13 Best for: Skip if: This cult favorite body oil has long been used by pregnant women to prevent stretch marks, and it's also a standout for fading old and new scars and hyperpigmentation. This formula has thousands of 5-star reviews on Amazon, and users say it's hydrating and soothing on patchy, dry skin in all seasons. To note: Some say the screw cap packaging can be tricky because the oil comes out quickly. Amazon Size: 4 ounces | Key ingredients: Carrot seed, squalene, evening primrose oil | Price per fluid ounce: $18.75 Best for: Skip if: Those with aging skin may struggle with crepiness, uneven tone and overall dullness, and Esker's formula works to remedy all those things. It contains nourishing antioxidants—carrot seed is its star ingredient—and squalene, evening primrose and jojoba oil to moisturize, smooth, soften and make skin appear more even overall. Amazon Size: 1.6 ounces | Key ingredients: Vitamin E, botanical oils | Price per fluid ounce: $20Best for: Skip if: Body oils naturally leave a sheen on skin, but this one contains micro flecks of shimmer to create an illuminating finish. It's made with seven botanical oils that offer up to eight hours of moisturization, and the vacation-inspired scent contains notes of vanilla, orange blossom and magnolia. Nuxe's muti-purpose oil can be used on the face and hair, too, and it's available in roll-on form. Sephora Size: 13 ounces | Key ingredients: Bacuri butter, prebiotic hibiscus, oil blend | Price per fluid ounce: $2Best for: Skip if: Sol de Janeiro's beach-inspired scents are legendary among tweens, teens and adults, and for good reason. Users rave about the woody floral scent of this cleansing shower oil, which has notes of vanilla orchid, sugared violet and sheer sandalwood. This formula contains an oil blend with coconut and sunflower seed oil to nourish, prebiotic hibiscus to support the skin's microbiome and bacuri butter to lock in moisture so skin stays hydrated throughout the day. The Forbes Vetted beauty and grooming team has researched, reported and written a wide variety of skincare stories on everything from the best vitamin C serums to the best LED face masks. Our general approach to determining the very best body oils was to meticulously research, report on and, in some cases, test a wide variety of available body oils on the market. Body oils are intended to be deeply moisturizing and in some cases offer extra skin benefits, but there are specific ingredients to seek out when shopping. 'A jojoba and coconut oil base helps to deeply hydrate the skin, allowing for better absorption and long-lasting moisture,' says massage therapist Matthew Perry, learning and development manager at The Now. He also recommends formulas containing vitamins A, C and E, as well as essential fatty acids. 'Rosehip oil helps regenerate skin cells and promote collagen production, and prickly pear seed oil aids in the prevention of skin damage and supports overall skin health with antioxidants,' he says. Perry also suggests calming ingredients such as sandalwood, reishi, and helichrysum to help soothe inflammation, reduce redness and restore balance to the skin. 'Depending on skin sensitivities or allergies, it's best to choose a clean, plant-based formula,' says Perry. 'Avoid body oils with sulfates, parabens or synthetic fragrances, which can irritate the skin. Opt for oils made with organic botanicals that can be easily absorbed.' Fragrance is very personal, so it's important to find a body oil with a scent you like as it will be with you for all, or at least most of, the day. Our best overall pick, L'Occitane's Almond Supple Skin Body Oil, has an almond and warm vanilla scent that is popular with users. Osea's Undaria Algae Body Oil, our choice for best smelling body oil, has a light citrus scent with notes of mango, mandarin, grapefruit, lime and cypress. Nuxe's Shimmering Dry Oil Huile Prodigieuse is also popular for its smell, which evokes vacation vibes with its notes of vanilla, orange blossom and magnolia. Some body oils, like the Maude Oil, are unscented, which can be a great choice if you have sensitive skin or are layering with any sort of perfume or other beauty products that have fragrance. There is a specific time to apply a body oil for peak nourishing and hydrating effects. 'It is best to use body oil right after a bath or shower, while your skin is damp, to help seal in the moisture,' says Perry. 'Alternatively, you can add a few drops of body oil to your bath for a soothing soak. For aromatherapeutic benefits, find a body oil with essential oils and breathe in deeply for a moment of calm.' What Oil Is Best For The Body? Our pick for best body oil overall is L'Occitane's Almond Supple Skin Body Oil for its softening properties and satiny smooth finish. For stretch marks, we like Bio-Oil's Skincare Oil, which works to reduce the appearance of stretch marks, acne scars and hyperpigmentation. If you have exceptionally dry skin, we recommend Roz's Willow Glen Treatment Oil.'Everyone can benefit from a good body oil to hydrate, balance and nourish the skin,' says Perry. Body oils are especially recommended for anyone living in a dry climate to moisturize and restore the skin's natural glow. Combine a body oil with a moisturizing body lotion to double down on the benefits, locking in hydration while delivering essential nutrients to the skin. Is Body Oil Better For You Than Lotion? They can both be a good fit, but they work slightly differently. 'Body oils work by locking in moisture and delivering nutrient-rich ingredients into the skin,' says Perry. 'Unlike water-based lotions, body oils create a protective barrier to help prevent moisture loss while nourishing the skin with antioxidants, vitamins and essential fatty acids that hydrate and restore balance.' What Body Oil Do Dermatologists Recommend? In general, dermatologists recommend body oil formulas with plant-based oils like jojoba, coconut and almond oil as they are deeply moisturizing and tend to be well-tolerated. Many dermatologists recommend Bio-Oil's Skincare Oil to reduce the appearance of acne scarring and stretch marks. If you have sensitive skin, dermatologists will tend to suggest something fragrance free, like the Maude Oil, which is also organic.
Bloomberg
2 hours ago
- Bloomberg
ADHD Feels Like It's Everywhere? Researchers See No Upswell
ADHD may seem like it's everywhere at the moment, but researchers found its prevalence hasn't changed much in recent years. A review by King's College London 's Institute of Psychiatry, Psychology & Neuroscience found that the proportion of people with a medical diagnosis for attention deficit hyperactivity disorder didn't increase meaningfully between 2020 and 2024. The findings published Thursday are based on four studies only, due to the poor quality of most of the others reviewed by the researchers.
