China delays return of Shenzhou-19 crewed spacecraft, Xinhua reports
BEIJING, April 29 (Reuters) - China has delayed the return of the Shenzhou-19 crewed spacecraft due to weather conditions at the landing site, the state-run Xinhua news agency reported on Tuesday.
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Reporting by Xiuhao Chen and Ryan Woo; Editing by Andrew Heavens
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Scottish Sun
5 hours ago
- Scottish Sun
New coronavirus only ‘one small step from spilling over into humans' and sparking widespread outbreak, say scientists
Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) A NEW coronavirus may only be "a small step away from spilling over into humans", scientists have warned - sparking fears of another pandemic. Scientists believe the variant, called HKU5-CoV-2, may infect a broader range of animals than Covid-19 and may have more potential for jumping between species. 1 Dr Michael Letko, a molecular virologist at WSU's College of Veterinary Medicine, lead the research into the concerning variant Credit: Ted S. Warren/College of Veterinary Medicine/WSU American scientists fear the virus - found in China - may be one small mutation away from also being able to infect humans, which could lead to a widespread outbreak. The new study, published in Nature Communications, looked at a lesser-known group of coronaviruses called merbecoviruses. It includes HKU5 and MERS-CoV, which is responsible for the deadly Middle East Respiratory Syndrome. First noted in 2012, the virus typically spreads from infected camels to humans causes severe respiratory disease, which can be fatal to 34 per cent of its victims. The research team, which included scientists at Washington State University (WSU), the California Institute of Technology and the University of North Carolina, sought to understand how merbecoviruses infiltrate the cells of their hosts. While most bugs in the group seemed to pose little threat to people, scientists said one subgroup, HKU5, has concerning traits. Michael Letko, a virologist at WSU's College of Veterinary Medicine, said: "Merbecoviruses – and HKU5 viruses in particular – really hadn't been looked at much, but our study shows how these viruses infect cells. "What we also found is HKU5 viruses may be only a small step away from being able to spill over into humans." Like other coronaviruses, merbecoviruses rely on a spike protein to bind to receptors and invade host cells. Dr Letko's team used virus-like particles containing the part of the spike protein responsible for binding to receptors and tested their ability to infect cells in their lab. World is not prepared for looming Disease X pandemic says Doctor Tedros Ghebreyesus While most merbecoviruses appeared unlikely to be able to infect humans, HKU5 viruses — which have been found across Asia, Europe, Africa and the Middle East — were shown to use a host receptor known as ACE2, the same used by the SARS-CoV-2 virus that causes Covid-19. But for now HKU5 viruses can only use the ACE2 gene in bats and can't deploy it on humans nearly as well. Examining HKU5 viruses found in Asia - where their host is the Japanese house bat - the researchers demonstrated some mutations in the spike protein that may allow the viruses to bind to ACE2 receptors in other species, including humans. 'These viruses are so closely related to MERS, so we have to be concerned if they ever infect humans,' Dr Letko said. 'While there's no evidence they've crossed into people yet, the potential is there — and that makes them worth watching.' Dr Letko said the study and its methods could be used for future research projects and to help the development of new vaccines and treatments. What is the new Covid variant confirmed in the UK? The new strain - called NB.1.8.1 - has been spotted in the parts of the UK, such as Ireland and Wales. It's also cropped up in Europe, the US and Australia, as well as Egypt, the Maldives, Thailand, China and Hong Kong. The World Health Organisation (WHO) recently issued a warning over NB.1.8.1, designating it as a "variant under monitoring" due to its global spread and key mutations. 'Despite a concurrent increase in cases and hospitalisations in some countries where NB.1.8.1 is widespread, current data do not indicate that this variant leads to more severe illness than other variants in circulation,' the WHO said. But while it may not be particularly severe, it may infect people more easily than previous variants, with some evidence suggesting that the variant binds more tightly to human cells. A recent study that has not yet been peer reviewed suggests that a person infected with NB.1.8.1 may be more likely to pass the virus on to someone else, compared to earlier variants. The WHO stressed that, based on available evidence, the variant's risk to public health was "low at the global level". "Currently approved Covid-19 vaccines are expected to remain effective to this variant against symptomatic and severe disease," it added. Symptoms include sore throat, fatigue, fever, mild cough, muscle aches and a blocked nose. Some people may also get gastrointestinal symptoms. It's not the first time concerns have been raised over HKU5. Earlier this year, Chinese scientists warned that HKU5-CoV-2 may be able to jump straight from bats to humans without another animal in between. This suggests a higher potential for zoonotic spillover - when a disease spreads from animal to human. If there is no 'intermediate 'middle animal', it becomes harder to predict and prevent spillover events through interactions such as wildlife trading or hunting. "There is the potential for this new virus to spillover to human, like previous coronaviruses including SARS-CoV-2," said Dr Gary R McLean, a research fellow at the Imperial College London, who was not involved in the study. But he noted that, so far, there is no "evidence" that HKU5-CoV-2 can infect people – the paper is based on tests in a laboratory, showing the bug's "potential". "Hopefully the Chinese authorities now have good surveillance systems in place and the laboratories work to rigid safety standards that minimise the risk of spillover occurring," he said. The WHO has previously listed MERS and Covid as two of several diseases - alongside the mysterious disease X - that could spark a pandemic, but for which there is no specific treatment or vaccine.
Daily Record
12 hours ago
- Daily Record
'I donated my mum's body to Alzheimer's research instead she was blown to pieces'
Her son said 'she was strapped in a chair, and a detonation took place underneath her' One Arizona man thought he was donating his mother's body to science after her harrowing descent in Alzheimer's - only to discover he had been sent her cremated arm before the rest of her body was strapped to a chair and blown up. Jim Stauffer cared for his mother Doris throughout her illness before she died at 74 in 2013. He decided to donate her brain to science hoping to contribute to a cure for Alzheimer's disease. The family contacted Biological Resource Center, a local company that brokered the donation of human bodies for research. Within the hour, BRC dispatched a driver to collect Doris. Jim signed a form authorizing medical research on his mother's body. Ten days later, Jim received his mother's cremated remains - but it turns out her ashes were made up of a singular arm sawn off from her body. The rest of her corpse had met a violent fate. Doris' brain never was used for Alzheimer's research. Instead, her body became part of an Army experiment to measure damage caused by roadside bombs, reports the Irish Star. Internal BRC and military records show that at least 20 other bodies were also used in the blast experiments without permission of the donors or their relatives, a violation of U.S. Army policy. Jim had also ticked a box specifically banning any kind of experiments on Doris. BRC sold donated bodies like Stauffer's for $5,893 each. Jim said: "She was strapped in a chair, and a detonation took place underneath her to get an idea of what the human body goes through when a vehicle is hit by an IED. There was wording on this paperwork about performing tests that may involve explosions, and we said, 'No'." Army officials involved in the project said they never received the consent forms that donors or their families had signed. Rather, the officials said they relied on assurances from BRC that families had agreed to let the bodies be used in such experiments. BRC, which sold more than 20,000 parts from some 5,000 human bodies over a decade, is no longer in business. Its former owner, Stephen Gore, pleaded guilty to fraud in 2022. In a statement to Reuters, Gore said that he always tried to honor the wishes of donors and sent consent forms when researchers requested them. Jim said of Gore "He didn't care about the families, he didn't care about the people." Jim learned of the fate of his mother's body from a Reuters reporter and "curled his lip in anger and clutched his wife Lisa's arm. "We did right," Lisa reassured him. "They just did not honor our wishes." No federal law regulates body brokers like BRC, and no U.S. government agency monitors what happens to cadavers pledged for use in medical education and research. "It is not illegal to sell a whole body or the parts of a body for research or education," said University of Iowa law professor Sheldon F. Kurtz, who helped modify the Uniform Anatomical Gift Act, which has been adopted by 46 states. Although the act was updated in 2006, Kurtz said, "the issue of whole bodies or body parts for research or education never came up during our discussions." Since then, the body trade has become big business. Only one state, New York, keeps detailed records on the industry. According to the most recent data available, companies that did business in New York shipped at least 100,000 body parts across the country from 2011 to 2014. Reuters obtained the data, which have never been made public, from the state's health department. "I feel foolish," said Jim. "I'm not a trusting person, but, you have no idea this is going on." Military officials said they took BRC's word that permission had been given. Records show at least 20 more bodies were blown up without consent.
Daily Mirror
12 hours ago
- Daily Mirror
'I donated mum's body to Alzheimer's research what happened next was horrifying'
Her son said 'she was strapped in a chair, and a detonation took place underneath her' One Arizona man thought he was donating his mother's body to science after her harrowing descent in Alzheimer's - only to discover he had been sent her cremated arm before the rest of her body was strapped to a chair and blown up. Jim Stauffer cared for his mother Doris throughout her illness before she died at 74 in 2013. He decided to donate her brain to science hoping to contribute to a cure for Alzheimer's disease. The family contacted Biological Resource Center, a local company that brokered the donation of human bodies for research. Within the hour, BRC dispatched a driver to collect Doris. Jim signed a form authorising medical research on his mother's body. Ten days later, Jim received his mother's cremated remains - but it turns out her ashes were made up of a singular arm sawn off from her body. The rest of her corpse had met a violent fate. Doris' brain never was used for Alzheimer's research. Instead, her body became part of an Army experiment to measure damage caused by roadside bombs, the Irish Star reports. Internal BRC and military records show that at least 20 other bodies were also used in the blast experiments without permission of the donors or their relatives, a violation of U.S. Army policy. Jim had also ticked a box specifically banning any kind of experiments on Doris. BRC sold donated bodies like Stauffer's for $5,893 each. Jim said: "She was strapped in a chair, and a detonation took place underneath her to get an idea of what the human body goes through when a vehicle is hit by an IED. There was wording on this paperwork about performing tests that may involve explosions, and we said, 'No'." Army officials involved in the project said they never received the consent forms that donors or their families had signed. Rather, the officials said they relied on assurances from BRC that families had agreed to let the bodies be used in such experiments. BRC, which sold more than 20,000 parts from some 5,000 human bodies over a decade, is no longer in business. Its former owner, Stephen Gore, pleaded guilty to fraud in 2022. In a statement to Reuters, Gore said that he always tried to honor the wishes of donors and sent consent forms when researchers requested them. Jim said of Gore "He didn't care about the families, he didn't care about the people." Jim learned of the fate of his mother's body from a Reuters reporter and "curled his lip in anger and clutched his wife Lisa's arm. "We did right," Lisa reassured him. "They just did not honor our wishes." No federal law regulates body brokers like BRC, and no U.S. government agency monitors what happens to cadavers pledged for use in medical education and research. "It is not illegal to sell a whole body or the parts of a body for research or education," said University of Iowa law professor Sheldon F. Kurtz, who helped modify the Uniform Anatomical Gift Act, which has been adopted by 46 states. Although the act was updated in 2006, Kurtz said, "the issue of whole bodies or body parts for research or education never came up during our discussions." Since then, the body trade has become big business. Only one state, New York, keeps detailed records on the industry. According to the most recent data available, companies that did business in New York shipped at least 100,000 body parts across the country from 2011 to 2014. Reuters obtained the data, which have never been made public, from the state's health department. "I feel foolish," said Jim. "I'm not a trusting person, but, you have no idea this is going on." Military officials said they took BRC's word that permission had been given. Records show at least 20 more bodies were blown up without consent.
