Mirror Biologics Announces Publication of Clinical Results Showing Potential for Allo-Priming to Provide Broad Protection to Elderly from Respiratory Viral Infection
Wesley Chapel, FL April 28, 2025 --( PR.com )-- Mirror Biologics, Inc today announces publication in the journal Vaccines the results of a clinical trial designed to test the ability of the experimental drug called AlloStim® to modulate the immune system of the elderly in such a manner that the elderly might respond to a viral infection in the same manner as a younger person responds. This type of vaccine protocol is called 'Allo-Priming' and was previously proposed as a possible ' Universal Vaccine ' against respiratory viral infection in the elderly.
The elderly population is at increased risk for severe disease from viral infections, especially viruses circulating in the community such as common cold viruses, the flu (influenza), COVID-19 and respiratory syncytial virus (RSV) leading to hospitalization.
With the aging population, the rates of hospitalization for severe disease from respiratory viral infections are rising. It has been reported that pneumonia is the third most common reason for hospitalization for persons aged 65 years and a major cause of death. The increased incidence of hospitalization in the elderly due to viral infections also has significant repercussions for public health systems and on healthcare costs.
Vaccination programs are designed to help protect against severe disease from some common respiratory viral infections, however the elderly often do not respond well to these vaccines and remain vulnerable to infection, especially those living in assisted living environments. Nursing home-acquired pneumonia occurs in an estimated 1-2 patients for every 1000 days of nursing home residence. Nursing home residents diagnosed with pneumonia and requiring hospitalization have reported mortality ranging from 13 to 41%.
The COVID-19 pandemic highlighted the scale of global unpreparedness to deal with the fast-arising needs of global health threats, causing untold fear and suffering for older people across the world. In addition, this recent pandemic highlighted the problems with attempting to vaccinate against a virus with the capability of rapidly changing its antigenic identity.
Dr. Michael Har-Noy, Chief Medical Officer at Mirror Biologics and corresponding author of the publication stated: 'In this clinical study, Mirror's scientists and clinical collaborators are addressing the problem of how to protect the elderly from the adverse effects of both known and future unknown viral threats, including a future virus with pandemic potential. The clinical results support the potential of our novel approach to modulate the immune system of the elderly in order to reset to be like a new young immune system that is capable of learning to protect showed great potential. Healthy adults over 65 years old were found to have acquired protection against common respiratory viruses that amplified over time, even though no viral antigens were incorporated in the formulation. We are now seeking a partner to assist us to complete the clinical testing necessary to make this experimental approach available to those in need.'
The results of this clinical trial suggest the Allo-Priming might provide the elderly with broad protection against severe disease from any type of respiratory viral infection, including common viruses and mutations, as well as protection from a future unknown pandemic virus without the need for prior knowledge of the type of virus and without the need for annual booster shots.
About Mirror Biologics
Mirror Biologics, Inc. is a private Delaware corporation with headquarters in Tampa, Florida. Mirror also has GMP manufacturing operations in Jerusalem, Israel and additional clinical operations in Thailand and Malaysia. The lead product candidate, AlloStim® is an 'off-the-shelf' non-genetically manipulated, living, immune cell immunotherapy protected by over 200 issued patents worldwide and derived from precursors purified from the blood of healthy donors. AlloStim® is a platform drug, that is broadly applicable to cancer and infectious disease indications. AlloStim® is being evaluated in clinical trials as a possible treatment for metastatic colorectal cancer and advanced liver cancer.
Contact Information:
Mirror Biologics, Inc.
Thu Bui
619-227-4872
Contact via Email
www.mirrorbio.com
Read the full story here: Mirror Biologics Announces Publication of Clinical Results Showing Potential for Allo-Priming to Provide Broad Protection to Elderly from Respiratory Viral Infection
Press Release Distributed by PR.com
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
2 hours ago
- Yahoo
UAMS chancellor stepping down after 7 years, returning to faculty
UAMS Chancellor Cam Patterson announces a new $31.7 million grant from the National Institutes of Health on July 10, 2024. (Mary Hennigan/Arkansas Advocate) The leader of Arkansas' largest healthcare system will step down after seven years for personal and medical reasons, the University of Arkansas for Medical Sciences announced Tuesday in a news release. Dr. Cam Patterson became the university's chancellor in June 2018. By giving up his position as chancellor and as UAMS Health CEO, he will return to being a faculty member in the university's cardiology department. Patterson 'is facing medical and personal issues that require more attention than he can give them while serving in the chancellor's position,' according to UAMS' news release. 'The work our team has done at UAMS over the last seven-plus years has been the high point of my career,' Patterson said in the release. 'We have a lot to be proud of and I've been the luckiest guy to be a part of it. I am excited about the opportunity to return to the faculty and engage more deeply in the academic and clinical missions at our institution.' UAMS System President Jay Silveria praised Patterson's leadership tenure in the release. 'Leading UAMS is a demanding task, and I appreciate Dr. Patterson's need to do what he feels is best for himself and his family and for the long-term success of the university,' Silveria said. 'His contributions to UAMS came through unusually restrictive times, and he should be celebrated for his efforts to push the institution forward while navigating a challenging environment.' Patterson 'oversaw both challenges and improvement in the university's economic outlook, despite the myriad issues presented by the COVID-19 pandemic and other unforeseen variables,' the release states. One such challenge was a conflict between state and federal mandates regarding COVID-19 vaccinations. The federal Centers for Medicare and Medicaid Services issued a mandate in November 2021 for health workers to be fully vaccinated or receive exemptions, with noncompliant facilities at risk of losing federal funding. The rule directly conflicted with a 2021 Arkansas law that said COVID-19 vaccination 'shall not be a condition of education, employment, entry, or services from the state or a state agency or entity' unless lawmakers approved an exception. Patterson sought an exemption and defended this decision before a legislative committee. Silveria will name an interim UAMS chancellor 'in the coming weeks' and start a national search for Patterson's permanent successor, the news release states. SUPPORT: YOU MAKE OUR WORK POSSIBLE
Yahoo
2 hours ago
- Yahoo
Harris County provides free summer nutrition program for youth
COLUMBUS, Ga. () — Harris County has started it's 'Seamless Summer Feeding Program' for Harris County residents during the summer months. The program is offered to any Harris County resident 18 years of age and younger. The residents of Harris County are provided with a free, well-balanced meal while school is out for summer break. Shelia Baker, the Assistant Superintendent of Support Services in the Harris County School District, shared how she wants this program to aid the children in the community. 'Summer meals are important to fight those food insecurities that some of our children who are most at need would need to have those meals that they would normally get during a school day,' Baker said. The program has two feeding sites available for residents. One is located at Harris County High School and the other at Parks Elementary School. The program offers breakfast and lunch, which are available for pickup or can be enjoyed on site. The intent of the program is to support the community and combat food insecurity, offering meals to those in need of them. Baker says residents who would normally consume their meals at school are now being provided with nutritious meals during the summer months. 'Also, summer meals are important because it keeps children healthy. Children are most active oftentimes during the summer, so it keeps them healthy in that regard,' Baker said. The nutrition program will be open from now until June 26th. For the Harris County High School site, breakfast meals are served from 7:30 a.m. – 8:15 a.m. Lunch meals are served 10:00 a.m. – 12:00 p.m. For the Parks Elementary School location, meals will only be available for pickup from 10:00 a.m. – 12:00 p.m. on Mondays. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
Yahoo
2 hours ago
- Yahoo
Hundreds of Bronx students shine at STEM expo at Yankee Stadium
THE BRONX, N.Y. (PIX11) — It's the third annual STEM Expo at Yankee Stadium! More than 400 students took part in the borough-wide STEM and science fair. From as young as 4 to eighteen years old, Bronx students had a blast inside Yankee Stadium, showcasing their love for science. More Local News Students presented the culmination of their hard work throughout the school year to one another, with hundreds of Bronx's best students presenting their final projects, covering science, math, engineering, gaming, and even robotics. Presentations included a robot that could plant wildflowers, experiments attempting solutions to rising sea levels, and projects delving into finding cures for cancer. Brian Smith with the Yankees says the yearly event is all about empowering the next generation of leaders. The competition is fierce, and everybody gets a medal and an experience of a lifetime. At times, it felt like the students were the teachers for the day. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
