NCCN Foundation Webinar Explains Why People with Cancer Should Consider Participating in Clinical Trials
Leading oncology experts explain the reasons for joining a cancer clinical trial and provide information on how to make it happen.
PLYMOUTH MEETING, Pa., March 17, 2025 /PRNewswire/ -- The National Comprehensive Cancer Network® (NCCN®) is sharing a webinar today that answers critical patient questions about cancer clinical trials. The newly released, on-demand webinar is titled 'Why Should I Consider a Clinical Trial?' It is available for free at NCCN.org/patientwebinars thanks to funding from the NCCN Foundation ®, along with a handout summarizing the key information.
Cancer clinical trials play a critical role in advancing treatment and improving patient outcomes. However, confusion about their purpose, benefits, and accessibility keeps many people from enrolling. This free webinar features leading experts in oncology and patient advocacy, who break down the complex concepts, making them accessible to all.
'Every standard treatment we have today was found by the intellect of science and the courage of patients who participated in clinical trials,' said Ann Fish-Steagall, RN, BSN, SVP Patient Services and Health Care Delivery, LUNGevity, who was one of the presenters. 'Clinical trials provide the medical community with important building blocks to further research and improve treatment options for all.'
'Clinical trials are a cornerstone of cancer research, but many patients are unsure how to approach them,' said Patrick Delaney, Executive Director, NCCN Foundation. 'Our goal with this webinar is to empower individuals with knowledge, address misconceptions, and make the whole process feel less daunting.'
'Diversity in clinical trial participation is essential to ensuring that new treatments work for everyone, regardless of their background,' Delaney continued. 'This session emphasizes the importance of inclusive participation and explores how to make that easier across every demographic.'
The webinar addressed key questions:
What is the Purpose of Cancer Clinical Trials?
What is the Role of Clinical Trials in Cancer Treatment, Including Risks and Benefits?
How do you Access Cancer Clinical Trials?
Tiffany Colvin, CCRP Sr. Director Clinical Trial Operations, Fred Hutch Cancer Center— another presenter—emphasized the dedication of the people involved in running a clinical trial, spanning various areas of healthcare: 'Without collaboration, we couldn't offer the latest and greatest treatment options. We hold ourselves accountable to transparency, quality, safety, and integrity in conducting these clinical trials. Trials offer patients early access to promising new therapies under strict supervision and comprehensive support from a dedicated research team.'
The newly posted on-demand webinar occurred live on February 28. Support was provided by AstraZeneca; Daiichi Sankyo; Genentech, Inc; and GSK.
NCCN has long advocated for clinical trial participation through the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®)—evidence-based, expert consensus-driven recommendations used to guide cancer care decisions around the world. On every guideline, the front cover includes the statement: 'NCCN recognizes the importance of clinical trials and encourages participation when applicable and available. Trials should be designed to maximize inclusiveness and broad representative enrollment.'
To learn more about NCCN's free patient information resources, including award-winning books, webinars, and more, visit NCCN.org/patients.
About the National Comprehensive Cancer Network
The National Comprehensive Cancer Network® (NCCN®) is marking 30 years as a not-for-profit alliance of leading cancer centers devoted to patient care, research, and education. NCCN is dedicated to defining and advancing quality, effective, equitable, and accessible cancer care and prevention so all people can live better lives. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) provide transparent, evidence-based, expert consensus-driven recommendations for cancer treatment, prevention, and supportive services; they are the recognized standard for clinical direction and policy in cancer management and the most thorough and frequently-updated clinical practice guidelines available in any area of medicine. The NCCN Guidelines for Patients® provide expert cancer treatment information to inform and empower patients and caregivers, through support from the NCCN Foundation ®. NCCN also advances continuing education, global initiatives, policy, and research collaboration and publication in oncology. Visit NCCN.org for more information.
About the NCCN Foundation
The NCCN Foundation is marking 15 years of empowering people with cancer and their caregivers by delivering unbiased expert guidance from the world's leading cancer experts through the library of NCCN Guidelines for Patients® and other patient education resources. The NCCN Foundation is also committed to advancing cancer treatment by funding the nation's promising young investigators at the forefront of cancer research. For more information about the NCCN Foundation, visit nccnfoundation.org.
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In a pooled analysis of ARAMIS and ARANOTE, ischemic heart disease occurred in 3.4% of patients receiving NUBEQA and 2.2% receiving placebo, including Grade 3-4 events in 1.4% and 0.3%, respectively. Ischemic events led to death in 0.4% of patients receiving NUBEQA and 0.4% receiving placebo. In ARASENS, ischemic heart disease occurred in 3.2% of patients receiving NUBEQA with docetaxel and 2% receiving placebo with docetaxel, including Grade 3-4 events in 1.3% and 1.1%, respectively. Ischemic events led to death in 0.3% of patients receiving NUBEQA with docetaxel and 0% receiving placebo with docetaxel. Monitor for signs and symptoms of ischemic heart disease. Optimize management of cardiovascular risk factors, such as hypertension, diabetes, or dyslipidemia. Discontinue NUBEQA for Grade 3-4 ischemic heart disease. Seizure – Seizure occurred in patients receiving NUBEQA. In a pooled analysis of ARAMIS and ARANOTE, Grade 1-3 seizure occurred in 0.2% of patients receiving NUBEQA. 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The most common laboratory test abnormalities (≥30%) are anemia (72%), hyperglycemia (57%), decreased lymphocyte count (52%), decreased neutrophil count (49%), increased AST (40%), increased ALT (37%), and hypocalcemia (31%). Clinically relevant adverse reactions in <10% of patients who received NUBEQA with docetaxel included fractures (8%), ischemic heart disease (3.2%), seizures (0.6%), and drug-induced liver injury (0.3%). Drug Interactions Effect of Other Drugs on NUBEQA – Concomitant use of NUBEQA with a combined P-gp and strong or moderate CYP3A4 inducer decreases darolutamide exposure which may decrease NUBEQA activity. Avoid concomitant use of NUBEQA with combined P-gp and strong or moderate CYP3A4 inducers. Concomitant use of NUBEQA with a combined P-gp and strong CYP3A4 inhibitor increases darolutamide exposure which may increase the risk of NUBEQA adverse reactions. Monitor patients more frequently for NUBEQA adverse reactions and modify NUBEQA dosage as needed. Effects of NUBEQA on Other Drugs – NUBEQA is an inhibitor of BCRP transporter. Concomitant use of NUBEQA increases the AUC and Cmax of BCRP substrates, which may increase the risk of BCRP substrate-related toxicities. Avoid concomitant use with drugs that are BCRP substrates where possible. If used together, monitor patients more frequently for adverse reactions, and consider dose reduction of the BCRP substrate drug. NUBEQA is an inhibitor of OATP1B1 and OATP1B3 transporters. Concomitant use of NUBEQA may increase the plasma concentrations of OATP1B1 or OATP1B3 substrates. Monitor patients more frequently for adverse reactions of these drugs and consider dose reduction while patients are taking NUBEQA. Review the Prescribing Information of drugs that are BCRP, OATP1B1, and OATP1B3 substrates when used concomitantly with NUBEQA. For important risk and use information about NUBEQA, please see the accompanying full Prescribing Information. About Metastatic Castration-Sensitive Prostate Cancer Prostate cancer is the second most common cancer in men and the fifth most common cause of cancer death in men worldwide.3 In 2020, an estimated 1.4 million men worldwide were diagnosed with prostate cancer, including nearly 300,000 men in the U.S., and nearly 375,000 men died from the disease worldwide.4,5 At the time of diagnosis, most men have localized prostate cancer, in which their cancer is confined to the prostate gland and can be treated with curative surgery or radiotherapy. Upon relapse when the disease will metastasize or spread, androgen deprivation therapy (ADT) is the cornerstone of treatment for this castration-sensitive, or hormone-sensitive, disease. 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About Bayer Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition. In line with its mission, "Health for all, Hunger for none," the company's products and services are designed to help people and the planet thrive by supporting efforts to master the major challenges presented by a growing and aging global population. Bayer is committed to driving sustainable development and generating a positive impact with its businesses. At the same time, the Group aims to increase its earning power and create value through innovation and growth. The Bayer brand stands for trust, reliability and quality throughout the world. In fiscal 2023, the Group employed around 100,000 people and had sales of 47.6 billion euros. R&D expenses before special items amounted to 5.8 billion euros. For more information, go to © 2025 BayerBAYER, the Bayer Cross and NUBEQA are registered trademarks of Bayer. Find more information at Our online press service is just a click away: Follow us on Facebook: Follow us on X: Forward-Looking Statements This release may contain forward-looking statements based on current assumptions and forecasts made by Bayer management. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. These factors include those discussed in Bayer's public reports, which are available on the Bayer website at The company assumes no liability whatsoever to update these forward-looking statements or to conform them to future events or developments. References Saad F, et al. Darolutamide in combination with androgen-deprivation therapy in patients with metastatic hormone-sensitive prostate cancer from the Phase III ARANOTE trial. J Clin Onc. 2024;42(36):4271-4281. NUBEQA® (darolutamide) [Prescribing Information]. Whippany, NJ: Bayer HealthCare Pharmaceuticals, Inc.; June 2025. Bray F, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Accessed June 2025. Prostate Cancer: Statistics. Accessed June 2025. American Cancer Society. Cancer Facts & Figures 2024. Accessed June 2025. James ND, et al. The Lancet Commission on prostate cancer: planning for the surge in cases. Lancet. 2024;403:1683-1722. NCT04736199. Darolutamide in Addition to ADT Versus ADT in Metastatic Hormone-sensitive Prostate Cancer (ARANOTE). Accessed June 2025. Piombino C, et al. De novo metastatic prostate cancer: are we moving toward a personalized treatment? Cancers (Basel). 2023;15(20):4945. Helgstrand JT, et al. Trends in incidence and 5-year mortality in men with newly diagnosed, metastatic prostate cancer - A population-based analysis of 2 national cohorts. Cancer. 2018;124(14):2931-2938. Buzzoni C, et al. Metastatic prostate cancer incidence and prostate-specific antigen testing: new insights from the European Randomized Study of Screening for Prostate Cancer. Eur Urol. 2015;68:885-890. Siegel DA, et al. Prostate cancer incidence and survival, by stage and race/ethnicity - United States, 2001-2017. MMWR Morb Mortal Wkly Rep. 2020;69:1473-1480. Hahn AW, et al. Metastatic castration sensitive prostate cancer: optimizing patient selection and treatment. Am Soc Clin Oncol Educ Book. 2018;23;38:363-371. View source version on Contacts Media: Polina Miklush, Tel +1 862.431.8817Email: Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
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RxWellness Spine & Health Acquires AllCare Chiropractic & Injury, Expands Multi-Regional Footprint with Four New Maryland Clinics
HERNDON, Va., June 3, 2025 /PRNewswire/ -- RxWellness Spine & Health, the Mid-Atlantic's leading natural-first healthcare clinic network and platform for integrative care, today announced the strategic partnership and acquisition of AllCare Chiropractic & AllCare Injury, LLC. The transaction adds four established, high-performing clinics—Silver Spring, Baltimore (Federal Hill), Bowie, and Laurel—to the RxWellness family, deepening the company's reach across Washington D.C., Northern Virginia, and Maryland. This expansion marks a pivotal step in RxWellness's multi-state growth strategy, reinforcing its leadership in natural-first, integrated care. Patients across the region will now gain broader access to RxWellness's signature approach—an outcomes-focused model that blends chiropractic, rehabilitation, and regenerative therapies. With a proven framework for scalable integration and expansion through both de novo clinics and strategic acquisitions, RxWellness is uniquely positioned to meet the rising demand for drug-free, results-driven healthcare. "When we founded RxWellness, the mission was simple—deliver life-changing care that's natural, innovative, and rooted in results," said Dr. Philip Golinsky, CEO and Founder. "To now see that vision stretch into multiple states, reaching thousands more people who are seeking a better alternative to drugs or surgery—that's an incredible honor. And we're just getting started." RxWellness is not a traditional chiropractic chain. It is a natural-first, patient-first healthcare platform, built around The Prescription to Wellness®—a proprietary, three-phase model that provides immediate relief, targets root causes, and supports long-term health and vitality. The company integrates chiropractic care, rehabilitative therapy, and regenerative medicine in a seamless, personalized experience designed for both clinical outcomes and operational efficiency. "This partnership is the result of years of behind-the-scenes work from our incredible team," said Phoebe Casey, Chief Strategist and Chief Operating Officer. "From providers to operations, everyone brought their A-game to bring this to life. We're proud to now serve these Maryland communities and deliver on our promise: the highest standard of natural healthcare, at scale." With over 150,000 patients treated, 7,500+ five-star reviews, and features in Modern Luxury DC, ABC7's Good Morning Washington, and The Inc. 5000 (two-time honoree), RxWellness is attracting attention as a category-defining brand at the forefront of natural, non-surgical care. This expansion is part of a broader, disciplined growth strategy that includes: Scalable acquisition integration Strong regional density for brand equity and operational leverage Advanced backend systems to support shared services across locations RxWellness' purposeful and forward-thinking growth strategy is one designed to elevate the standard of care, broaden community access, and partner with leading clinics that align with the company's patient-first philosophy. As the company continues to grow, it remains focused on long-term value creation, with a vision to scale into a national leader in natural healthcare, underpinned by operational excellence, patient trust, and an unwavering mission: to elevate patient health and empower lives by providing natural care solutions for pain-free, drug-free living. About RxWellness Spine & HealthRxWellness Spine & Health is a nationally recognized healthcare organization specializing in non-surgical, natural pain relief and holistic wellness solutions. With a multidisciplinary approach that integrates chiropractic, rehabilitation, physical medicine, and regenerative therapies, RxWellness is redefining the standard for patient-centered care. The company's mission is to make natural healthcare the preferred path—not the alternative. For media inquiries or more information, contact:Dylan CaseyDirector of Marketingdylan@ View original content to download multimedia: SOURCE RxWellness Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
