Latest news with #AMPK
Yahoo
22-05-2025
- Health
- Yahoo
Noster research: Gut bacteria-derived molecule found to shrink fat cells and improve metabolism
KYOTO, Japan, May 14, 2025 /PRNewswire/ -- Joint study by University of Shizuoka, Kobe University, and Noster Inc. uncovers a novel postbiotic pathway for obesity prevention. A new collaborative study from the University of Shizuoka, Kobe University, and Kyoto-based biotech company Noster Inc. has revealed that a natural compound produced by beneficial gut bacteria can directly act on fat cells, reducing their size and improving cellular metabolism. These findings, published in Nutrients, point to a new mechanism by which microbiome-derived compounds may help combat obesity and related diseases. The compound—HYA (10-hydroxy-cis-12-octadecenoic acid)—is made when certain gut bacteria, including Lactobacillus, metabolize linoleic acid, a common dietary fat. While HYA has previously been shown to support gut health and inflammation control, this study is the first to demonstrate that it directly alters the behavior of fat cells themselves. "We've known that metabolites from gut bacteria can influence the body, but this is the first clear evidence that HYA acts directly on adipose tissue," says Tetsuya Hosooka, Associate Professor at the University of Shizuoka and senior author of the study. "The discovery that gut bacteria can regulate fat cell function adds an exciting new dimension to our understanding of host–microbe communication." Key findings In the study, mice fed a high-fat diet were supplemented with HYA for five weeks. The fat cells themselves were significantly smaller compared to mice not receiving HYA—indicating a reduction in adipocyte hypertrophy, which is closely associated with insulin resistance and chronic inflammation. The researchers then examined the effects of HYA on cultured fat cells. In these experiments, HYA-treated adipocytes accumulated less fat, showed reduced expression of fat synthesis genes (FAS, ACC1, SCD1), and increased expression of genes involved in fat oxidation (CPT1A). This shift was linked to activation of AMP-activated protein kinase (AMPK), a key energy-regulating enzyme in cells. Importantly, the study found that HYA boosts intracellular calcium levels in fat cells, which in turn activates AMPK. This newly described mechanism is independent of GPR40 and GPR120, two receptors previously thought to mediate HYA's effects, suggesting that a different signaling route is involved. These results reinforce the idea that postbiotics—beneficial substances produced by gut microbes—can influence metabolic health by acting directly on distant tissues. Reference Matsushita R, Sato K, Uchida K, Imi Y, Amano R, Kasahara N, Kitao Y, Oishi Y, Kawaai H, Tomimoto C, et al. A Gut Microbial Metabolite HYA Ameliorates Adipocyte Hypertrophy by Activating AMP-Activated Protein Kinase. Nutrients, 2025; 17(8):1393. Glossary HYA – A natural compound produced by gut bacteria from dietary fat Adipocyte – A cell that stores fat in the body AMPK – An enzyme that regulates how cells use energy Postbiotic – A health-promoting compound made by gut microbes Hypertrophy – The enlargement of individual cells, often seen in obesity Abbreviations AMP (adenosine monophosphate), FAS (fatty acid synthase), ACC1 (acetyl-CoA carboxylase 1), SCD1 (stearoyl-CoA desaturase 1), CPT1A (carnitine acyltransferase 1A), GPR (G protein-coupled receptor) About Noster Inc. Noster Inc. is a biotechnology company based in Kyoto, Japan. The company focuses on postbiotics—compounds produced by gut bacteria—to develop new approaches to healthcare. By collaborating with universities and research institutes, Noster aims to translate microbiome science into real-world solutions for chronic diseases such as obesity, diabetes, and inflammatory conditions. CEO: Kohey Kitao Head Office & Research Center: 35-3 Minamibiraki, Kamiueno-cho, Muko, Kyoto 617-0006, Japan Website: Contact Information Public Relations: Nanami Akatsuka Tel: +81-75-921-5303 / Fax: +81-75-924-2702 Email: contact@ Photo: View original content to download multimedia: SOURCE Noster Inc Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
14-05-2025
- Health
- Yahoo
Noster research: Gut bacteria-derived molecule found to shrink fat cells and improve metabolism
KYOTO, Japan, May 14, 2025 /PRNewswire/ -- Joint study by University of Shizuoka, Kobe University, and Noster Inc. uncovers a novel postbiotic pathway for obesity prevention. A new collaborative study from the University of Shizuoka, Kobe University, and Kyoto-based biotech company Noster Inc. has revealed that a natural compound produced by beneficial gut bacteria can directly act on fat cells, reducing their size and improving cellular metabolism. These findings, published in Nutrients, point to a new mechanism by which microbiome-derived compounds may help combat obesity and related diseases. The compound—HYA (10-hydroxy-cis-12-octadecenoic acid)—is made when certain gut bacteria, including Lactobacillus, metabolize linoleic acid, a common dietary fat. While HYA has previously been shown to support gut health and inflammation control, this study is the first to demonstrate that it directly alters the behavior of fat cells themselves. "We've known that metabolites from gut bacteria can influence the body, but this is the first clear evidence that HYA acts directly on adipose tissue," says Tetsuya Hosooka, Associate Professor at the University of Shizuoka and senior author of the study. "The discovery that gut bacteria can regulate fat cell function adds an exciting new dimension to our understanding of host–microbe communication." Key findings In the study, mice fed a high-fat diet were supplemented with HYA for five weeks. The fat cells themselves were significantly smaller compared to mice not receiving HYA—indicating a reduction in adipocyte hypertrophy, which is closely associated with insulin resistance and chronic inflammation. The researchers then examined the effects of HYA on cultured fat cells. In these experiments, HYA-treated adipocytes accumulated less fat, showed reduced expression of fat synthesis genes (FAS, ACC1, SCD1), and increased expression of genes involved in fat oxidation (CPT1A). This shift was linked to activation of AMP-activated protein kinase (AMPK), a key energy-regulating enzyme in cells. Importantly, the study found that HYA boosts intracellular calcium levels in fat cells, which in turn activates AMPK. This newly described mechanism is independent of GPR40 and GPR120, two receptors previously thought to mediate HYA's effects, suggesting that a different signaling route is involved. These results reinforce the idea that postbiotics—beneficial substances produced by gut microbes—can influence metabolic health by acting directly on distant tissues. Reference Matsushita R, Sato K, Uchida K, Imi Y, Amano R, Kasahara N, Kitao Y, Oishi Y, Kawaai H, Tomimoto C, et al. A Gut Microbial Metabolite HYA Ameliorates Adipocyte Hypertrophy by Activating AMP-Activated Protein Kinase. Nutrients, 2025; 17(8):1393. Glossary HYA – A natural compound produced by gut bacteria from dietary fat Adipocyte – A cell that stores fat in the body AMPK – An enzyme that regulates how cells use energy Postbiotic – A health-promoting compound made by gut microbes Hypertrophy – The enlargement of individual cells, often seen in obesity Abbreviations AMP (adenosine monophosphate), FAS (fatty acid synthase), ACC1 (acetyl-CoA carboxylase 1), SCD1 (stearoyl-CoA desaturase 1), CPT1A (carnitine acyltransferase 1A), GPR (G protein-coupled receptor) About Noster Inc. Noster Inc. is a biotechnology company based in Kyoto, Japan. The company focuses on postbiotics—compounds produced by gut bacteria—to develop new approaches to healthcare. By collaborating with universities and research institutes, Noster aims to translate microbiome science into real-world solutions for chronic diseases such as obesity, diabetes, and inflammatory conditions. CEO: Kohey Kitao Head Office & Research Center: 35-3 Minamibiraki, Kamiueno-cho, Muko, Kyoto 617-0006, Japan Website: Contact Information Public Relations: Nanami Akatsuka Tel: +81-75-921-5303 / Fax: +81-75-924-2702 Email: contact@ Photo: View original content to download multimedia: SOURCE Noster Inc Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Business Upturn
02-05-2025
- Health
- Business Upturn
BerbaLean Under Review: Empower Health Labs Berberine AMPK Activator Supplement with Hydrochloric Acid
New York, May 02, 2025 (GLOBE NEWSWIRE) — In This Article, You'll Discover: What makes BerbaLean™ by Empower Health Labs a unique metabolism-boosting formula a unique metabolism-boosting formula How BerbaLean™ works to combat sluggish metabolism using science-backed mechanisms A clear explanation of BerbaLean ingredients, including the roles of Berberine and Hydrochloride (HCL) The real science behind AMPK activation, thermogenesis, lipolysis, and fat-burning at rest A breakdown of the potential BerbaLean side effects and who should avoid taking it Customer feedback and BerbaLean reviews from verified buyers who achieved significant weight loss A transparent overview of BerbaLean pricing, package options, and refund policy Where to buy BerbaLean™ online, including details on bonuses and shipping Why this natural metabolism supplement may offer a sustainable, stimulant-free approach to weight loss TL;DR – Summary of This Article BerbaLean™ by Empower Health Labs is an advanced weight loss and metabolic support formula designed to address the root causes of a sluggish metabolism. Unlike conventional diet pills, BerbaLean™ supports the body's natural ability to burn fat through AMPK activation, thermogenesis, and improved energy conversion. Featuring clinically studied BerbaLean ingredients such as Berberine and Hydrochloride (HCL), the supplement aims to enhance nutrient absorption, curb cravings, and regulate blood sugar levels. The product is well-reviewed, boasting a 4.92-star average from over 50,000 reviews, and is manufactured in a GMP-certified, FDA-registered facility in the USA. BerbaLean™ is suitable for individuals seeking a natural metabolism booster without synthetic stimulants. Transparent BerbaLean pricing includes free U.S. shipping and bonus eBooks on multi-bottle purchases. With a 90-day money-back guarantee, users can try it risk-free. In summary, this review highlights BerbaLean™ as a credible and scientifically aligned solution for those looking to enhance their metabolism and achieve sustainable weight loss. Have you ever felt like your metabolism has slowed considerably, making it nearly impossible to lose weight, no matter how hard you try? I've been there and know what it's like to struggle with a sluggish metabolism, where every diet and exercise routine was useless. That's when I came across BerbaLean™, a formula by Empower Labs that claims to fix a sluggish metabolism and help you finally start burning fat the way you've always wanted. Now, I'm not usually one to jump on every health trend that comes my way. I like to do my research first, especially regarding supplements. But BerbaLean caught my attention because it claims to tackle the root cause of slow metabolism. It's not advertised as a quick fix or a magic pill; it's about working with your body to boost its natural metabolism. But let's be honest: with every supplement, there are always pros and cons. And while BerbaLean has its share of rave reviews, it's essential to know what you're putting into your body. That's why I decided to dig deeper into what makes BerbaLean tick—how it works, what's inside, and the side effects that might come with it. Because at the end of the day, it's not just about losing weight; it's about doing it naturally, safely, and sustainably. We'll dive into everything about this specialized formula in this Empower Labs BerbaLean™ review. Formulation: Advanced Weight Loss and Metabolic Health Formula and Support Advanced Weight Loss and Metabolic Health Formula and Support Bottle Contains: 60 capsules / 30 Servings 60 capsules / 30 Servings Ingredients: Berberine, HCL Berberine, HCL Recommended Dosage: 2 capsules daily 2 capsules daily Consumers Rating: 4.92 Stars From 5 Based on 50,000 Reviews 4.92 Stars From 5 Based on 50,000 Reviews Price: Starts at $69 per bottle or as Low as $59, and $49.00 Each with Free Shipping and Bonuses Starts at $69 per bottle or as Low as $59, and $49.00 Each with Free Shipping and Bonuses Refund Policy: 90-day refund policy How BerbaLean™ Works: Renewing A Sluggish Metabolism The idea of fixing my sluggish metabolism on my own sounded too good to be true. But once I started looking into how it works, I realized it's not just a marketing gimmick. BerbaLean uses a targeted approach beyond suppressing appetite or giving you a quick energy boost. BerbaLean starts working when taken in the recommended dose of two capsules each day. Customers report seeing results within a week and some within three months of consistently taking it. What is a Sluggish Metabolism? Before diving into how BerbaLean™ works, it's essential to understand what it means to have a sluggish metabolism. If you're like me, you've probably noticed that some people can eat whatever they want and not gain an ounce, while others seem to gain weight just by looking at food. That's where metabolism comes in—the process by which our bodies convert what we eat into energy. A sluggish metabolism means your body isn't burning calories as efficiently as it should, leading to weight gain, fatigue, and difficulty losing weight. I learned that various factors can cause a slow metabolism, including genetics, age, hormone imbalances, lack of physical activity, and prolonged dieting. When your metabolism slows, your body stores more fat, causing your energy levels to drop. This is where BerbaLean steps in, targeting the very core of these issues. Rebooting Metabolism: The Core Mechanism So, how does BerbaLean reboot a sluggish metabolism? The answer lies in its ability to influence the body's metabolic rate—the speed at which it burns calories. BerbaLean is unique because it doesn't just focus on the typical symptoms of slow metabolism. Instead, it works deeper to optimize the body's internal processes. From what I've learned, BerbaLean™ boosts the basal metabolic rate (BMR), the number of calories your body needs to maintain essential functions at rest, such as breathing, body temperature, cell production and growth, brain and nerve function, muscle contraction, and circulation. By increasing BMR, BerbaLean forces the body to burn more calories, even at rest. This means that you're not only burning calories when you're working out but also when you're sitting and sleeping. It's like turning your body into a calorie-burning machine operating around the clock. Targeting Fat Stores: The Next Step We all know that losing weight isn't just about burning calories—it's about burning the right calories, mainly from fat stores. One of the standout features of BerbaLean is its ability to target these stubborn fat stores specifically. You know, those areas where fat seems to stick no matter what you do—like the belly, thighs, and arms. BerbaLean doesn't just burn calories; it focuses on breaking down stored fat and using it for energy. BerbaLean targets fat by activating lipolysis, the breakdown of fats into free fatty acids and glycerol, making it easier for the body to use these as fuel. This is crucial because, without breaking down these fat stores, the body would continue to rely on other energy sources, like carbohydrates, instead of using the excess fat. By promoting lipolysis, BerbaLean ensures that your body taps into these reserves, effectively shrinking those stubborn areas over time. Activating Thermogenesis: The Heat Factor Thermogenesis is another key mechanism that BerbaLean uses to fight sluggish metabolism. Thermogenesis is the body's heat production process and plays a significant role in regulating metabolism. When thermogenesis is activated, the body burns more calories to produce heat, which can lead to weight loss. BerbaLean works by triggering the body's natural thermogenic processes, increasing the heat on your metabolism. Think of it like turning up the thermostat in your body's calorie-burning furnace. This process helps burn more calories and makes your body more efficient in using energy from food. It's like turning every meal into an opportunity to burn fat rather than store it. What I found particularly interesting is that BerbaLean doesn't rely on artificial stimulants to activate thermogenesis. Instead, it supports the body's ability to produce heat and burn calories, making it a more natural approach. By boosting thermogenesis, BerbaLean helps you burn more calories during exercise and at rest, making weight loss more achievable. Boosting Energy Levels and Combating Fatigue One of the most frustrating aspects of a sluggish metabolism is the constant feeling of fatigue. I always felt tired, no matter how much sleep I had or how well I ate. This fatigue can make staying active and maintaining a healthy lifestyle even harder. But BerbaLean doesn't just help with weight loss; it also tackles the energy slump that comes with a slow metabolism. By revving up your metabolism and promoting the breakdown of fat for energy, BerbaLean provides a steady source of fuel for your body. This not only helps with weight loss but also boosts overall energy levels. Once my metabolism started to pick up, I felt more energetic and less sluggish throughout the day. This boost in energy made it easier to stay active, which helped keep my metabolism running smoothly. It's like a positive cycle: more energy leads to more activity, which leads to an even faster metabolism. Ready to transform your energy, mood, and weight? Don't wait—BerbaLean™ is your science-backed solution to reviving a sluggish metabolism naturally. How the Ingredients in BerbaLean™ Help You Lose Weight Regarding supplements, I've always believed that knowing what's inside the bottle is just as important as knowing how it works. With BerbaLean, two primary ingredients make this formula stand out: Berberine and HCL (Hydrochloride). Both play a critical role in how BerbaLean helps boost metabolism, target stubborn fat, and support overall health. Let's dive into these ingredients to understand their roles, benefits, and why they're a significant addition to metabolism-boosting supplements. Berberine: The Natural Powerhouse When I first read that Berberine was a main ingredient in BerbaLean, I was curious because it's an ingredient I had no understanding of what it could do. Berberine is a bioactive compound extracted from several plants, including a group of shrubs called Berberis (Barberry), goldenseal, Oregon grape, and Chinese Goldthread. It's been used in traditional Chinese and Ayurvedic medicine for centuries for its anti-inflammatory and antimicrobial properties. But recently, it's gained attention for its potential benefits in managing blood sugar, metabolism, and weight. How Berberine Works in the Body Berberine works by activating an enzyme inside our cells called AMP-activated protein kinase (AMPK). AMPK is often called the body's 'metabolic master switch' because it significantly regulates metabolism. When AMPK is activated, it helps to balance energy production and consumption in the body. This process is essential for burning calories and preventing fat storage. When I learned about Berberine's ability to activate AMPK, it made sense why it's included in BerbaLean. By turning on this enzyme, Berberine can help increase the body's ability to burn calories, even at rest. This activation also helps regulate blood sugar levels, which is crucial because blood sugar spikes can increase fat storage, especially around the belly area. So, Berberine boosts metabolism and supports overall metabolic health, making achieving and maintaining a healthy weight easier. Supporting Blood Sugar and Insulin Sensitivity One of the standout benefits of Berberine is its impact on blood sugar control. Blood sugar and insulin levels are major players for anyone struggling with weight, especially around the midsection. When blood sugar levels spike, the body releases insulin to help cells absorb glucose. However, over time, cells can become resistant to insulin, leading to higher blood sugar levels and more fat storage. This cycle is prevalent in people with sluggish metabolism. Berberine has been shown to improve insulin sensitivity and activate AMPK, which means it helps cells respond better to insulin, allowing for more efficient blood sugar regulation. It also helps your body use sugar more effectively, reducing the likelihood of storing it as fat. I found this aspect of Berberine particularly appealing because it doesn't just target one aspect of metabolism but improves how the body handles nutrients. Anti-Inflammatory and Antioxidant Properties Another fascinating aspect of Berberine is its anti-inflammatory and antioxidant properties. Chronic inflammation can slow metabolism and contribute to weight gain, especially in people with metabolic disorders. By reducing inflammation, Berberine helps create a healthier environment inside the body, allowing metabolism to function more efficiently. Berberine's antioxidant properties also help fight oxidative stress, which can damage cells and slow metabolic processes. The National Institutes of Health studies show that oxidative stress can impair metabolic processes, and berberine's antioxidant action can help restore normal function, contributing to a more active and efficient metabolism. It's like giving your body the right tools to operate smoothly without the hiccups that can lead to a sluggish metabolism. Berberine's Impact on Gut Health Gut health is another area where Berberine shines. A healthy gut is crucial for an efficient metabolism because it's where nutrients are absorbed and processed. Berberine helps support a balanced gut microbiome, which can improve digestion and nutrient absorption. A healthy gut means fewer digestive issues and better overall energy levels, contributing to a more active metabolism. What I found particularly interesting is that Berberine can even help reduce the absorption of dietary fats, which means fewer calories from fat make it into the bloodstream. This can be a game-changer for anyone struggling with weight, as it directly reduces the calorie intake from fat without requiring drastic dietary changes. HCL (Hydrochloric Acid): The Catalyst for Enhanced Absorption Next, we have HCL, which might initially sound a bit unusual. When I first saw HCL listed as an ingredient, I immediately thought of hydrochloric acid—the stuff in our stomach that helps digestion. However, in the context of BerbaLean, HCL serves a different and equally important purpose. HCL is often included in supplements to enhance digestion and stomach acidity, which allows for the more effective absorption of other key ingredients. The Role of HCL in Enhancing Absorption One of the biggest challenges with supplements is ensuring that the body efficiently absorbs the active ingredients in this BerbaLean formula. It's one thing to swallow a pill; it's another for your body to benefit from what's inside. This is where HCL comes into play. By enhancing the absorption of Berberine and other compounds, HCL ensures that the body gets the maximum benefit from the supplement. HCL does this by lowering the pH in the stomach, which creates a more acidic environment conducive to breaking down foods to improve the absorption of minerals and nutrients and curb cravings. When I learned about this, it made perfect sense—our stomach naturally uses acid to digest food, so adding HCL can help the body more effectively process the supplement. This means you're not just taking BerbaLean and hoping for the best; HCL ensures that the active ingredients are delivered where they're needed most. Supporting Digestive Health Beyond absorption, HCL also plays a role in supporting digestive health. Many people with sluggish metabolisms also experience digestive issues like bloating, gas, or indigestion. By promoting a more acidic environment in the stomach, HCL helps improve the breakdown of food, reducing the likelihood of these uncomfortable symptoms. Better digestion means better nutrient absorption, directly supporting a more efficient metabolism. I noticed that after starting BerbaLean, not only did my energy levels improve, but my digestion felt smoother, too. It wasn't just about losing weight; it was about feeling lighter and more comfortable after meals, which made a big difference in my day-to-day life. The HCL Acid Factor: Debunking Myths I had some reservations when I first saw HCL on the ingredient list. Who wants to put more acid in their body, right? However, the form of HCL used in supplements is safe and specifically designed for treating metabolic alkalosis. One thing to keep in mind is that if you have conditions like acid reflux or ulcers, adding more acid to your stomach might not be the best idea. It's always a good idea to start slow and pay attention to how your body reacts. In my case, BerbaLean's formulation with HCL didn't cause any issues, but everyone's body is different. HCL's Role in Metabolism and Weight Loss While HCLis a key component of stomach acid but doesn't directly burn fat or boost metabolism, it breaks down food, especially proteins, and can stop cravings, which is crucial. Think of it as the catalyst for improving everything else in BerbaLean. HCL indirectly supports all the metabolic benefits BerbaLean offers by ensuring the body can effectively absorb the vitamins and nutrients it needs. Another interesting point is that proper absorption can prevent nutrient deficiencies, which can slow metabolism. For instance, deficiencies in key vitamins and minerals can lead to fatigue, poor digestion, and weight gain—all symptoms of a sluggish metabolism. By enhancing absorption, HCL helps ensure the body has the nutrients to keep higher energy levels and the metabolism running smoothly. Struggling to lose weight despite eating right and exercising? BerbaLean™ helps your body work smarter, not harder—start your transformation today. BerbaLean™ Pros and Cons Pros Activate the fat-burning enzyme AMPK Revives slow metabolism Stops cravings for food It gives you more energy Lose weight without giving up your favorite foods or spending hours in a gym. It may help control blood sugar and improve sleep. It may help lower cholesterol and triglyceride levels and improve insulin resistance Bonus guides with bulk purchases Safe for everyday use Free US Shipping Non-GMO formula 90-Day Money Back Guarantee Made in the USA in an FDA-approved facility that follows GMP guidelines Cons Anyone pregnant, nursing, taking medication, or with a medical condition should not take this formula until consulting a doctor before using BerbaLean. Some may experience stomach upset when first taking BerbaLean if they have a sensitive stomach. Unsatisfied customers must return all of the bottles, even if they are empty, for a full refund. Anyone who is taking a berberine supplement with medications to slow blood clotting might increase the risk of bruising and bleeding. BerbaLean Customer Reviews Jenny D – Verified Purchase 'I shed an amazing 34 pounds in just 2 months…' 'I shed an amazing 34 pounds in 2 months, and I've kept it off for two years. This transformation has revamped my entire lifestyle. I've recommended it to my friends and family, and they, too, have experienced similar benefits: reduced cravings and a significant energy boost.' Janice Tucker – Verified Purchase '…complete lifestyle transformation…' 'BerbaLean helped me lose 31 pounds in under two months and had fantastic outcomes: no more cravings and had a surge in energy.' BerbaLean Pricing and Refund Policy Empower Health Labs offers consumers significant savings, free delivery to the United States, and two free eBooks to enhance their overall health. BerbaLean offers three pricing options, with 30 servings in each bottle: 1 Bottle : $69.00 + Free Shipping in the US : $69.00 + Free Shipping in the US 3 Bottles : $59.00 Each at $177.00 Total (saves $30) + Free Shipping in the US : $59.00 Each at $177.00 Total (saves $30) + Free Shipping in the US 6 Bottles: $49.00 Each at $294 Total (saves $120) + Free Shipping in the US Digital eBook bonuses can be downloaded instantly with purchases of 3 or six bottles of BerbaLean. These are: How to Adopt a Nutrient-Rich Lifestyle with Fruits and Veggies Easy Home Detox: Quick and Simple Cleansing Steps for Optimal Weight Loss Every purchase comes with a 90-day refund policy, so you can try BerbaLean risk-free. If it doesn't work, request a refund, and customers must return all of the bottles, even if they are empty, to get a refund—with no questions asked! Unsatisfied customers can contact Empower Health Labs by phone or by sending an email to: Customer service at (800)-974-2790 or [email protected]. Conclusion After thoroughly researching BerbaLean, I feel it's not just another quick-fix weight loss supplement. Its ingredients target sluggish metabolism with the help of the potent ingredients listed in this BerbaLean review and ensure sustainable weight loss results. From boosting energy to supporting overall health, I experienced a genuine difference. If you're struggling with stubborn weight, BerbaLean might be the game-changer you've been looking for. Visit the official Empower Health Labs website to purchase BerbaLean™ today with free shipping and two bonus eBook guides. Frequently Asked Questions (FAQ) About BerbaLean™ What is BerbaLean™? BerbaLean™ is a natural metabolism-boosting supplement developed by Empower Health Labs. It's formulated to support fat-burning, control cravings, and enhance energy levels using clinically-researched ingredients like Berberine and Hydrochloride (HCL). How does BerbaLean™ work to support weight loss? BerbaLean™ works by activating AMPK, the body's 'metabolic master switch,' which increases the basal metabolic rate (BMR). This results in the body burning more calories—even at rest. It also promotes lipolysis (fat breakdown), thermogenesis (calorie-burning heat production), and improves energy levels while balancing blood sugar and insulin sensitivity. What are the main ingredients in BerbaLean™? BerbaLean™ contains: Berberine – Supports AMPK activation, boosts metabolism, reduces inflammation, regulates blood sugar, and improves gut health. – Supports AMPK activation, boosts metabolism, reduces inflammation, regulates blood sugar, and improves gut health. HCL (Hydrochloride) – Enhances nutrient absorption, supports digestion, and ensures optimal uptake of Berberine. What are the benefits of taking BerbaLean™? Revives a sluggish metabolism Burns fat more efficiently, even while at rest Reduces hunger and cravings Enhances energy levels Supports blood sugar balance and insulin sensitivity May help with cholesterol and triglyceride levels Improves digestion and nutrient absorption Promotes healthy weight loss without extreme diets or workouts Are there any side effects of BerbaLean™? BerbaLean™ is considered safe for daily use for most individuals. However, some users with sensitive stomachs may experience mild digestive discomfort when first starting. Individuals who are pregnant, nursing, or taking medications (especially blood thinners or diabetic medications) should consult a healthcare provider before using BerbaLean™. Who should avoid taking BerbaLean™? Pregnant or breastfeeding women Individuals with a sensitive stomach People on medications for blood clotting or diabetes Anyone with known gastrointestinal conditions like ulcers or acid reflux (due to the HCL content) How soon can I expect to see results with BerbaLean™? Some users report noticeable results within the first week, while others may see significant changes over two to three months of consistent use. Effects vary based on individual metabolism, activity levels, and overall lifestyle. What makes BerbaLean™ different from other metabolism boosters? BerbaLean™ targets the root cause of slow metabolism rather than just offering temporary energy boosts. Its ingredients are backed by science, focus on AMPK activation, and work without relying on harsh stimulants, making it a natural and sustainable weight loss aid. What is the recommended dosage for BerbaLean™? The suggested dose is 2 capsules daily, taken with a meal to enhance absorption and minimize stomach discomfort. Is BerbaLean™ made in the USA? Yes. BerbaLean™ is manufactured in an FDA-registered, GMP-certified facility in the United States, ensuring high standards for purity, safety, and quality. How much does BerbaLean™ cost? 1 Bottle : $69.00 (30-day supply) + Free US Shipping : $69.00 (30-day supply) + Free US Shipping 3 Bottles : $59.00 each (Save $30) + Free US Shipping + 2 Bonus eBooks : $59.00 each (Save $30) + Free US Shipping + 2 Bonus eBooks 6 Bottles: $49.00 each (Save $120) + Free US Shipping + 2 Bonus eBooks What is the BerbaLean™ refund policy? BerbaLean™ is backed by a 90-day money-back guarantee. If you're not satisfied for any reason, you can return your bottles—even empty ones—for a full refund. However, all bottles must be returned for a refund to be processed. How can I contact BerbaLean™ customer service? For questions, refunds, or order support: Phone : (800)-974-2790 : (800)-974-2790 Email: [email protected] Are there any bonuses included with a BerbaLean™ purchase? Yes! Orders of 3 or more bottles include two free digital eBooks: How to Adopt a Nutrient-Rich Lifestyle with Fruits and Veggies Easy Home Detox: Quick and Simple Cleansing Steps for Optimal Weight Loss These are designed to complement BerbaLean's metabolism-boosting effects and promote a healthier lifestyle. Start your sustainable weight loss journey today with BerbaLean™—the formula that targets fat at the source and delivers long-term results. Company : BerbaLean : BerbaLean Address : 285 Northeast Ave Tallmadge, OH 44278 U.S.A. : 285 Northeast Ave Tallmadge, OH 44278 U.S.A. Email : [email protected] : [email protected] Order Phone Support: (800)-974-2790 Disclaimers and Disclosures The information provided in this article is for general educational and informational purposes only and is not intended as, nor should it be considered a substitute for, professional medical advice, diagnosis, or treatment. The content reflects the opinions of the original author(s) based on publicly available sources and/or personal experiences. Always consult with a qualified healthcare professional before starting any supplement, especially if you are pregnant, nursing, taking medication, or have any pre-existing medical conditions. Neither the publisher nor any associated parties, including affiliates and distribution partners, are responsible for any errors or omissions in this content or for any outcomes resulting from its use. While every effort has been made to ensure accuracy, results may vary from person to person, and no guarantee is made regarding the efficacy or safety of any product discussed herein. Any claims made about the effectiveness of the BerbaLean™ product have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This article may contain affiliate links. If you click on a link and make a purchase, the publisher or its partners may receive a commission at no additional cost to you. This helps support the continued creation and distribution of content. However, the inclusion of affiliate links does not influence the integrity of the information presented. All product names, logos, brands, and trademarks are the property of their respective owners. Any references to specific products or companies do not constitute an endorsement or guarantee by the publisher or its affiliates. By accessing or using this content, readers acknowledge and agree to these terms. For any questions or concerns related to the content or its accuracy, please contact the product manufacturer directly. Disclaimer: The above press release comes to you under an arrangement with GlobeNewswire. Business Upturn takes no editorial responsibility for the same.
Web Release
01-03-2025
- Health
- Web Release
LYMA FORMULA NOW INCLUDES NEW INGREDIENT FOR "EXERCISE IN A PILL" TO COMBAT THE EFFECTS OF A SEDENTARY LIFESTYLE
The rise of the desk jockey sees Brits sit for as long as 8.9 hours per-day*2 and Americans sit almost 6 hours per-day*2 – and our sedentary lifestyles are known to be damaging to our health The LYMA Supplement is the only award-winning nutraceutical to include ten patented, peer-reviewed ingredients (targeting focus, immunity, beauty), in the doses proven to work, and it is now adding an eleventh The new ingredient is a patented adaptogen that studies have found to mimic some of the effects of exercise such as fat-burning and energy producing metabolic processes* It can be beneficial for those on Ozempic, as studies have is found to support muscle maintenance*4 – muscle loss is a commonly reported side effect of the weight loss drug LYMA Supplement £199 / $269 is available NOW ( The LYMA Supplement is an award-winning nutraceutical that includes 10 patented, peer-reviewed ingredients and now LYMA is adding an 11th ingredient to the formulation that can deliver a metabolic reset*5. Available from 25th February 2025. WHY METABOLISM IS OUR SUPERPOWER Together with optimal nutrition, the human body requires regular exercise and the need to be active as a prerequisite for human health. Our nutritional needs are rooted in life conditions that existed over 10,000 years ago, only today, diet and lifestyles are radically different. When firing on all cylinders, our metabolism regulates the body's whole system processes, but the rise in technology (which has resulted in us leading sedentary lifestyles) together with the ageing process has resulted in a dramatic rise in cases of underperforming metabolisms, weight gain and inflammation – the catalyst of many modern chronic diseases. The WHO statistics outline a concerning trend among adults worldwide, uncovering nearly one-third (31 per cent) of adults do not meet their recommended levels of physical activity, an increase of 5% since 2010*. THE PROVEN POWER OF THE NEW LYMA SUPPLEMENT The introduction of ActivAMP® into the LYMA Supplement adds to the brand's anti-ageing innovations. ActivAMP® is a patented adaptogenic herb extract of gynostemma pentaphyllum containing a family of compounds that upregulate alarmins, including the sestrins, which are produced during exercise. The production of these sestrins activates an energy-sensing enzyme called AMP-kinase (AMPK), typically stimulated by physical activity and fasting, the AMPK enzyme increases the production of cellular energy and metabolic activity throughout the body . The Science: Professor Paul Clayton PhD, clinical pharmacologist and world leading expert in the fast-developing science of preventative ageing, and LYMA Director of Science: 'The LYMA Supplement is already a world class product, and never before has so much validated science and patented technology been combined into one formula and this new ingredient further adds to that. ActivAMP® is the first of a new class of natural compounds called 'exercise mimetics'. Hailed by some as 'exercise in a pill,' it flips on AMPK – the metabolic master switch, to induce the benefits of exercise. ActivAMP® is also recommended for anyone taking Ozempic, as it may protect the muscle loss induced by weight-loss injections, which over the long haul, carries some major health risk factors. If you choose to use a semaglutide injectable like Ozempic, adding ActivAMP®, may ensure that you lose fat while keeping your valuable muscle.' LYMA Founder, Lucy Goff also comments 'When I read our science team's report on the research behind this new ingredient, I knew straight away we had to formulate it into the LYMA Supplement. This clinically proven ingredient is the only one of its kind, with clinical trials to prove it can help burn fat and enhance performance for years to come. It presents all the metabolic benefits of exercise in a pill, that's truly remarkable for people with busy lives that want to maximise their wellbeing.' A DAILY DOSE OF THE NEW LYMA SUPPLEMENT CAN TURBO-CHARGE A WORKOUT For those who are fully dedicated to their workouts the ingredient is also found to have some positive implications for athletic performance*5. It is also found to optimize glucose uptake, enabling muscles to better convert glucose to energy for higher endurance and less physical fatigue*3*5. The condition and operation of the metabolism is fundamental to long-term health, particularly when regulating metabolic activity in the liver, skeletal muscle and brain. When we master our body's metabolic switch, longevity becomes a realisable goal for all.
