24-04-2025
Man first in world to join new part of brain cancer trial in Leeds
A man has become the first in the world to join the new part of a brain cancer trial in Leeds.
Ian Johnson, 50, is taking part in a study testing a new drug called AZD1390, which is being used alongside radiotherapy to treat glioblastoma—a type of brain cancer.
The drug is designed to make radiotherapy more effective by stopping cancer cells from repairing themselves after treatment.
Mr Johnson, a senior crown prosecutor and father of two, was diagnosed with glioblastoma in December 2023.
He said: "The diagnosis was a huge shock; I'd always been healthy and had no medical issues before this."
He had surgery to remove the tumour in January, followed by radiotherapy and chemotherapy.
Unfortunately, a scan showed the tumour had returned.
Because his body didn't respond well to chemotherapy, Mr Johnson's doctor referred him to Leeds to explore other treatment options, which is when he learned about the trial using AZD1390.
Mr Johnson added: "The team here has been incredible—supportive, kind, and always there to answer questions."
Since starting the treatment, Mr Johnson says he's been able to continue doing the things he loves, like walking, birdwatching, and spending time with his family.
