Latest news with #AlbertEinsteinCollegeofMedicine
Yahoo
16-05-2025
- Entertainment
- Yahoo
Bobbi Brown, Lauren Bush Lauren and More Honored at Einstein College of Medicine Spirit of Achievement Luncheon
On Tuesday, the Albert Einstein College of Medicine's Women's Division hosted its annual Spirit of Achievement luncheon honoring makeup artist and Jones Road Beauty founder Bobbi Brown (trailblazer award honoree); founder and chief executive officer of lifestyle brand committed to solving world hunger Feed Lauren Bush Lauren (visionary award honoree), chair and professor at Albert Einstein College of Medicine Teresa Bowman Ph.D. (Ruth L. Gottesman award for scientific advancement honoree) and philanthropist and member of board of trustees at Albert Einstein College of Medicine Linda Altman (leadership award honoree). The event, held at the Rainbow Room in New York, is the longest running benefit luncheon in the city. Prior to the lunch, honorees and attendees mingled over mimosas and posed for the step-and-repeat. More from WWD Skin Care Pioneer Ole Henriksen Announces 'The Glowing Man' Biopic in Cannes All the Beauty Retail Expansions of 2025 Twelve Years After Hitting the Market, Men's Grooming Brand Harry's Is Launching a New Razor Both Brown and Bush Lauren were humbled to be honored with an award from an institution centered around science for their work in beauty and world hunger, respectively. 'I'm honored to share this award with some of my role models, from Eleanor Roosevelt to Gloria Steinem to Meryl Streep,' Brown said during her speech. 'I'm just a nice Jewish girl from Chicago who decided to become a makeup artist. How? Why am I in this room? I'm not sure.' Brown also joked that she hopes 'to tell all the other creative kids that don't get good grades in math and science, there is hope….I'm very honored, especially for someone that got Ds in science to get this science award. It's pretty amazing, but it's really about all the amazing doctors and women that make a big difference.' Ahead of the event, Bush Lauren said: 'I'm very honored to be honored with Bobbi, who's an old friend of mine, and just from an amazing organization doing really important research and clinical care. It's a little surreal, to be honest.' Like Brown, Bush Lauren was humbled by the array of past honorees, which also include Donna Karan, Diane von Furstenberg, Evelyn Lauder and Iris Apfel. Bush Lauren added: '[It's] an honor in itself to be considered amongst those women. For me, I've just been held up and lifted up by so many women, obviously my mom, my family, my sister, my girlfriends and fellow female entrepreneurs have like been my little tribe during the last 20 years of building Feed. Without them and that support Feed certainly would not be here.' While Brown and Bush Lauren were honored for their successes, the focus throughout the event was on the scientific advancements coming out of the college, including Bowman's research on blood stem cells via zebrafish, which respond similarly to humans. Best of WWD The Best Makeup Looks in Golden Globes History A Look Back at Golden Globes Best Makeup on the Red Carpet, From Megan Fox to Sophia Loren [PHOTOS] The Best Hairstyles in Golden Globes History
Yahoo
14-05-2025
- Entertainment
- Yahoo
Robert De Niro Hits the Cannes Red Carpet with Partner Tiffany Chen, Plus Eva Longoria, Selena Gomez and More
Stars have been everywhere this week. At the Cannes Film Festival, Robert De Niro steps out for a rare appearance with his partner, Tiffany Chen, while Eva Longoria dazzles fans upon arrival. In New York, Only Murders in the Building costars Martin Short, Selena Gomez and Steve Martin promote their show while Nick Jonas is out and about. Here are the best photos of celebs out and about this week. Come back tomorrow for more of the latest A-list outings! Robert De Niro and his partner Tiffany Chen arrive in style on the red carpet at the Cannes Film Festival in France on May 13. Martin Short, Selena Gomez and Steve Martin celebrate the upcoming fifth season of Only Murders in the Building at Disney Upfront in New York City on May 13. Eva Longoria is all smiles on the red carpet at the Cannes Film Festival in France on May 13. Nick Jonas looks cool as ever as he takes a stroll around New York City on May 13. Bella Hadid waves to the crowd at the Cannes Film Festival in France on May 13. Quentin Tarantino embraces his wife Daniella at the Cannes Film Festival in France on May 13. Pete Davidson steps out with girlfriend Elsie Hewitt in New York City on May 13. Jason Weinberg, Demi Moore and Merritt Johnson attend Family Equality's Night at the Pier event to raise money for LGBTQ+ families in New York City on May 12. Chandra Wilson reps Grey's Anatomy at Disney Upfront in New York City on May 13. Alfonso Ribeiro looks polished in purple while out in New York City on May 13. Bobbi Brown and Lauren Bush Lauren show their support at Albert Einstein College of Medicine's Spirit Awards in New York City on May 13. Heidi Klum looks radiant in a pink floral dress on her way to the Cannes Film Festival in France on May 13. Renée Zellweger gets sleuthing on the set of Only Murders in the Building in New York City on May 13. Timothée Chalamet and Kylie Jenner sit courtside at the playoff game between the Boston Celtics and the New York Knicks on May 12 in New York City. Travis and Jason Kelce host the Amazon Upfront, announcing the streamer's new projects, in New York City on May 12. Kate Middleton greets guests at the British Fashion Council in London on May 12, where she presents the Queen Elizabeth II Award for British Design. Amy Poehler and Tina Fey reunite at an NBCUniversal event announcing the network's primetime show lineup. Cardi B and NFL star Stefon Diggs fuel dating rumors as they celebrate the New York Knicks' win against the Boston Celtics on May 12 in New York City. Kelly Ripa, Nicole Scherzinger, and Mark Consuelos smile for a group shot while attending the Family Equality Gala on May 12 in New York City. Blake Shelton jams out at NBC's TODAY Citi Concert Series on May 13 in New York City. Justin Theroux walks the blue carpet at the Webby Awards in New York City on May 12. John Cena and wife Shay Shariatzadeh match in purple looks the Amazon Upfront on May 12 in New York City Dave Bautista and Jason Momoa make a grand arrival at the Amazon Upfront in New York City on May 12. Lizzo shows off her new blonde hair at the Amazon Upfront in New York City on May 12. Jurnee Smollett and Ciara celebrate the grand opening of Tory Burch's new flagship store on Rodeo Drive in Los Angeles on May 12. Pauline Chalamet, Kate Hudson and Jodie Turner-Smith look chic at the opening of Tory Burch's new flagship store in Los Angeles on May 12. Ryan Reynolds rocks a double-tan outfit on The Late Show with Stephen Colbert on May 12 in New York City. Maren Morris performs on The Tonight Show Starring Jimmy Fallon on May 12 in New York City Eva Longoria heads out of her hotel in Paris to the Cannes Film Festival on May 13. Robert De Niro and girlfriend Tiffany Chen arrive at the Cannes Film Festival in France on May 13. Halle Berry waves to fans at the Cannes Film Festival on May 13. Tom Brady shows off his famous football handling skills at the Fox Upfront in New York City on May 12. Elizabeth Hurley and Brendan Fraser smile at the Fox Upfront in New York City on May 12. Rob Lowe and Jon Hamm pose together at the Fox Upfront in New York City on May 12. Usher wears Emory University's robes as he gives their graduation commencement speech in Atlanta on May 12. Halle Berry radiates movie star energy as she enters Hotel Martinez in Paris ahead of the Cannes Film Festival on May 12. Tom Cruise dons a classic suit with a patterned tie as he prepares for the BFI Fellowship celebration for him in London on May 12. Days after hosting the ACM Awards, Reba McEntire flies to New York City for the NBCUniversal Upfront event on May 12. Snoop Dogg, in a bright blue tracksuit, carries a speaker as he enters Watch What Happens Live with Andy Cohen in New York City on May 12. Lizzo rocks full platinum blonde hair as she steps out in a black dress at Watch What Happens Live in New York City on May 12. Hannah Waddingham glows on the red carpet at the BFI Chair's Dinner in London on May 12. Bella Hadid goes blonde as she arrives at her hotel ahead of Cannes Film Festival in France on May 12. Gayle King and Nicole Scherzinger pop in vibrant colors at SiriusXM Studios in New York City on May 12. Heidi Klum and her husband Tom Kaulitz match in black at the Cannes Film Festival in France on May 12. Andrew Garfield and Monica Barbaro visit Isa Antonetti during a production of Buena Vista Social Club on Broadway in N.Y.C. on May 11. Kylie Jenner wears a pink bikini while enjoying the sun on the Turks and Caicos Islands on May 10. A shaded DJ Khaled holds up the MCM x Snipes collaboration at a launch party held at We The Best x Snipes in Miami. Ashley Madekwe, Shea McGee and Jamie Chung are ready for the spring at An Evening with Tuckerknuck and Studio McGee in West Hollywood, California, on May 8. Jordan Chiles tips her cowboy hat at an afterparty for Beyoncé's Cowboy Carter Tour in L.A. powered by SirDavis American Whisky, Marriott Bonvoy and EDITION on May 8. Terry Crews shows off his biceps in Spotify, FC Barcelona and Travis Scott's Cactus Jack merchandise in Barcelona on May 10. Walton Goggins delivers his opening monologue in his Saturday Night Live hosting debut in New York City on May 10. Gwen Stefani gets ready to take the stage at Wango Tango in Huntington Beach, California, wearing all denim on May 10. Jessie J, her son Sky, mom Rose Cornish and boyfriend Chanan Safir Colman have a family day at The Wiggles' tour stop in London on May 9. Abbott Elementary's William Stanford Davis stops by The Jennifer Hudson Show for a May 12 episode in Burbank, California. A casual Jennifer Lawrence totes a big yellow bag on a stroll in New York City on May 11. Daniel Dae Kim arrives at a closing night screening of Yellow Face in San Francisco on May 11. Michelle Williams' character is pregnant for A Place in Hell scene in New York City on May 11. Harry Hamlin holds an acting masterclass at the SAG-AFTRA Foundation in Los Angeles on May 11. Nicole Scherzinger wears a bright pink biker jacket to the opening night of The Last Bimbo of the Apocalypse in New York City on May 11. Benson Boone and his girlfriend Maggie Thurmon hold hands on a day around Malibu, California, on May 11. Host Alan Cumming looks dapper at the 2025 BAFTA TV Awards in London on May 11. Amber Rose reps the Houston Rockets at the Baddies Africa premiere in West Hollywood, California, on May 11. Megan Thee Stallion is a sheer beauty at the Gold Gala in Los Angeles on May 10. Also at the Gold Gala, H.E.R. sports a stylish pair of shades in Los Angeles on May 10. Meghan Trainor prepares to head onstage in a jewel-studded two-piece at Wango Tango in Huntington Beach, California, on May 10. Teddi Mellencamp arrives in white to Wango Tango in Huntington Beach, California, on May 10. A blonde Doja Cat strikes a pose on the Wango Tango red carpet in Huntington Beach, California, on May 10. Yvette Nicole Brown and her husband Anthony Davis are happy to be at the Spring Break Gala in Los Angeles on May 10. Dressed in a black dress, Michelle Monaghan steps out in the East Village in N.Y.C. on May 10. Timothée Chalamet cheers on the New York Knicks in game three against the Boston Celtics in N.Y.C. on May 10. Justin Theroux bundles up to attend the Poker Face pop-up with his dog Kuma in New York City on May 9. Saweetie celebrates Kali Uchis' new album Sincerely at a party in Hollywood, California, on May 9. Taraji P. Henson rocks an edgy look on The Jennifer Hudson Show for a May 9 episode in Burbank, California. Khloé Kardashian sparkles in sequins with an award at the German Perfume Award Duftstars in Dusseldorf, Germany, on May 8. Nicola Coughlan radiates old Hollywood glam at the 2025 BAFTA Television Awards in London on May 11. Tom Cruise speaks as a guest at the British Film Institute's Southbank location in London on May 11. Heidi Klum smiles for the cameras while walking through the Nice Côte d'Azur Airport ahead of the 2025 Cannes Film Festival in France on May 11. Chanel Iman and Victoria Monét celebrate a new Chasa collection at Porta Via in Beverly Hills, Calif., on May 9. Alan Cumming attends the 2025 BAFTA Television Awards in a dazzling blue blazer and leopard print in London on May 11. Viola Davis is joined by her daughter Genesis at the City Year Los Angeles' 14th annual Spring Break Gala held at SoFi Stadium in Inglewood, Calif., on May 9. Meghan Trainor makes a glamorous appearance in a pink bow outfit and pearl set at iHeartRadio's 102.7 KIIS FM Wango Tango in Huntington Beach, Calif., on May 10. Quinta Brunson smiles for the camera as she attends the City Year Los Angeles' Spring Break Gala in Inglewood, Calif., on May 9. Mariska Hargitay poses with her son August for a photo as they arrive at the Knicks playoff game at Madison Square Garden in New York City on May 10. Robert Irwin attends the Steve Irwin Gala held in honor of his late father to support the Wildlife Warriors conservationist organization at Las Vegas' Bellagio Resort & Casino on May 10. John Legend, Chrissy Teigen, Sandra Oh and Tan France put on their finest ensembles as they attend the Founders Party at the Gold House Gold Gala on May 10 in Los Angeles. Questlove, Fred Armisen, Dave Grohl and Judd Apatow attend the Ladies & Gentlemen...50 Years of SNL Music event at the Grammy Museum in Los Angeles on May 10. Amber Riley models a chic all-white look as she attends the Black Excellence Brunch by BET PLUS celebrating the Usher: Rendezvous in Paris concert film on May 10 in Los Angeles. Darren Barnet, Brenda Song, Ming-Na Wen, and Harry Shum Jr. pose for a photo as they attend the fourth annual Gold House Gold Gala on May 10 in Los Angeles. Colton Underwood speaks onstage at the third annual Hollywood & Mind Summit on May 9 in Los Angeles. Victoria Monét attends Mother's Day Party With a Purpose presented by the Elaine Welteroth and birthFUND in L.A. on May 10. Mariska Hargitay looks effortlessly cool outside Madison Square Garden in N.Y.C. on May 10. Tyra Banks strikes a pose while attending The Silver Party at The Hermitage in Sydney, Australia on May 10. Ben Stiller sits courtside during a match between the Boston Celtics and the New York Knicks at Madison Square Garden in New York City on May 10. Sophia Bush smiles wide at Mother's Day Party With a Purpose hosted by Elaine Welteroth and birthFUND in Los Angeles on May 10. John Krasinski, Sarah Snook and Matt Damon pose backstage at the Broadway play The Picture of Dorian Gray at The Music Box Theatre in New York City on May 9. Billie Eilish speaks on stage during the Billie Eilish and Support+Feed Present: OVERHEATED Berlin event at Festsaal Kreuzberg in Berlin on May 9. Sarah Paulson makes a fashion forward appearance at the Miu Miu Tales and Tellers event at New York City's Terminal Warehouse on May 9. Justin Hartley is dashing in a suit and shades as he is seen out in New York City on May 9. Hugh Jackman greets fans after performing with Ella Beatty in the off-Broadway play Sexual Misconduct of the Middle Classes on May 8 in New York City. Patti LaBelle takes to the stage on the opening night of The Queens! 4 Legends. 1 Stage Tour at the Michelob ULTRA Arena in Las Vegas on May 9. Shia LaBeouf attends the premiere and Q&A for his new film Henry Johnson in Santa Monica, Calif., on May 9. Chaka Khan gives a showstopping perfrormace onstage during the first night of The Queens! 4 Legends. 1 Stage Tour on May 9 in Las Vegas, Amy Grant lights up the stage as she performs at the Ryman Auditorium in Nashville on May 9. Jesse Metcalfe speaks onstage during day two of the Environmental Media Association IMPACT Summit 2025 presented By Toyota on May 9 in West Hollywood. Buffy the Vampire Slayer co-stars Alyson Hannigan and Sarah Michelle Gellar reunite at the Sirius XM studios in New York City on May 9. Gwyneth Paltrow unveils The Forest Within, an immersive recreation of a Korean forest, in New York City on May 9. Eva Longoria flashes a smile as she arrives at her hotel in Paris on May 9. Henry Golding grabs a quick bite at the Casting Directors' Luncheon in London on May 9. Lily Allen looks chic at the Casting Directors' luncheon in London on May 9. Nina Dobrev and fiancé Shaun White take a stroll through New York City with their dog on May 9. Natasha Lyonne looks gorgeous in a see-through dress after appearing on Late Night with Seth Meyers on May 9 in New York City. Jeff Timmons, Justin Jeffre, Nick Lachey and Drew Lachey of 98 Degrees make a stop at the Sirius XM Studios on May 9 in New York City. Tony Hawk hangs with pal Tony the Tiger at a celebration for his new video game, Tony Hawk's Pro Skater 3 + 4 in Los Angeles on May 8. Read the original article on People
Medscape
06-05-2025
- Health
- Medscape
Novel Shoes May Cut Low Back Pain, Delay Knee Arthroplasty
INCHEON, South Korea — A shoe-based biomechanical intervention worn for a short time each day may achieve greater improvements in low back pain and greater reductions in the risk for total knee replacement surgery than standard physical therapy, according to two studies presented at the World Congress on Osteoarthritis (OARSI) 2025 Annual Meeting. 'If you've ever watched somebody who has pain — whether it's knee pain, hip pain, back pain — they walk a little strange,' said presenter Matthew Bartels, MD, MPH, director of Rehabilitation Medicine and professor of physical medicine and rehabilitation at Montefiore Medical Center and Albert Einstein College of Medicine in New York City. But walking differently to compensate for pain can actually make the problem worse, directing the ground force through the affected area of the body, whether the knee or lower back. Bartels presented data from two studies of the US Food and Drug Administration–cleared shoe-based intervention, which 'alters the foot's pressure points to reduce loads, minimize symptoms, and promote neuromuscular control training using adjustable, convex pods under the sole,' according to the researchers. The first was a randomized controlled trial comparing the effects of the intervention and standard physical therapy on pain in 162 patients with low back pain. Participants were randomized in a 2:1 ratio either to the shoe-based intervention from AposHealth — which was individually tailored and calibrated six times over 1 year — or to standard physical therapy. In addition to being presented at OARSI, the trial was recently published in Global Spine Journal . At 1 year after randomization, those who used the shoe-based intervention reported a significantly greater mean 3.5-point reduction in their pain scores, as measured on a 10-point numeric rating scale, compared with a mean 1.8-point reduction in those who received physical therapy. The participants in the intervention also reported better secondary outcomes, including greater improvements in their Patient-Reported Outcomes Measurement Information System function scores, gait speed, and overall quality of life. Bartels told Medscape Medical News that the intervention was likely to have greater compliance than physical therapy because patients could use it at home for as little as 15 minutes at a time and feel the benefits pretty quickly. 'We all know that if you have knee or back pain, physical therapy will make you better, but the problem is, people don't keep the exercises up,' he said. 'This is a treatment that you put the shoes on, and you just wear them doing normal activities for a period, so it doesn't take time out of your day.' Bartels' own experience of his patients using the shoes was that even if patients did stop wearing them once their symptoms improved, they often started using them again if their symptoms returned, 'so they kind of self-dose,' he said. The second study Bartels presented was a poster detailing the results of a retrospective registry review of 95 patients with knee osteoarthritis (OA) who had been prescribed the shoe intervention after exhausting other nonsurgical options to see whether it was associated with a reduction in the likelihood of total knee replacement surgery. The study was also published last year in the Journal of Musculoskeletal Research . After an average follow-up time of 5.6 years, 12.6% of the patients using the shoe had undergone total knee replacement compared with 34.3% of a control group of patients from the same period who received traditional physical therapy. 'Increased use of biomechanical intervention to treat knee OA may help reduce some of the burden on healthcare and society associated with end-stage knee OA by delaying or avoiding surgery,' the researchers wrote. Commenting on the two studies, physical therapist and epidemiologist Garrett Bullock, PhD, DPT, of Wake Forest University School of Medicine, Winston-Salem, North Carolina, said, 'For a specific type of patient that has tried exercise interventions, has tried medication interventions, and a combination of both, that has a decent amount of physical activity, it may be something to explore, particularly to maintain neutral balance or create a better line through the foot.' Bullock told Medscape Medical News that there was always a risk that patients wouldn't adhere to physical therapy, so an intervention that provided education and the tools for self-efficacy could help them to manage their own symptoms.
Miami Herald
23-04-2025
- Health
- Miami Herald
Matter Bio Announces Landmark Collaboration to Decode Exceptional Longevity at Unprecedented Scale
Groundbreaking longevity research initiative brings together leading scientists and institutions to decode the genetic basis of extreme lifespan BROOKLYN, NEW YORK / ACCESS Newswire / April 23, 2025 / Matter Bio, a pioneering biotechnology company focused on extending healthspan through advanced genetic interventions, today announced the launch of a groundbreaking longevity research initiative that brings together leading scientists and institutions to decode the genetic basis of extreme lifespan. Leveraging multi-omics technologies - including genomics, transcriptomics, proteomics, and metabolomics- and processing this unique dataset with cutting age AI analysis, the project will integrate data from human supercentenarians and exceptionally long-lived mammalian species, representing one of the most comprehensive efforts in aging science to date. A World-Class Alliance This collaborative network unites Matter Bio's research and development capabilities with premier scientists from top institutions dedicated to uncovering the foundations of healthy aging, including: George Church, Ph.D. (Harvard and MIT)Professor of Genetics at Harvard Medical SchoolNir Barzilai, M.D. (Albert Einstein College of Medicine)Director of the Institute for Aging ResearchJan Vijg, Ph.D. (Albert Einstein College of Medicine)Professor and Chairman of the Department of Gorbunova, Ph.D. (University of Rochester)Co-director of the Rochester Aging Research CenterYousin Suh, Ph.D. (Columbia University)Director of Reproductive Aging and Chaired ProfessorPaul Robbins, Ph.D. (University of Minnesota)Co-Director of the Institute on the Biology of Aging and Metabolism (iBAM)Laura Niedernhofer, M.D., Ph.D. (University of Minnesota)Co-Director of the Institute on the Biology of Aging and Metabolism (iBAM) Additional collaborators include experts affiliated with the American Federation for Aging Research (AFAR). Decades of research have shown a striking correlation: species with extended lifespans consistently exhibit superior genome stability, resulting not only in longer life, but also in drastically reduced rates of cancer and other age-related diseases. This project aims to build on those findings at an unprecedented scale. "At Matter Bio, we're determined to shift the paradigm from disease treatment to preventative health solutions that can significantly extend the healthy human lifespan," said Chris Bradley, M.S., CEO of Matter Bio. "This collaboration brings together extraordinary expertise to drive one of the most comprehensive efforts in longevity science ever undertaken." The consortium will analyze biological data from over 10,000 human centenarians, 20,000 members of their families and will compare these sequences against over 200,000 regular human genome sequences. This data will be analyzed alongside samples from a combination of more than 300 long-lived and short-lived animal species, including the Greenland Shark, thought to be capable of living over 400 years. Multiple tissues and sample types will be studied for each species, generating tens of thousands of data points for the largest comparative analysis of its kind. By systematically comparing long-lived organisms to shorter-lived controls, the research team aims to identify key pro-longevity genes and molecular pathways. These findings will serve as a powerful foundation for developing targeted therapeutics and interventions to extend healthspan and combat age-related diseases. "By uniting large-scale genomic data, powerful computational tools, and advanced gene delivery platforms, we have a rare opportunity to intervene in aging processes in ways never before possible," said Harvard geneticist and co-founder of Matter Bio, Dr. George Church. The initiative also benefits from the expertise of pioneers in aging research. Nir Barzilai, M.D., of Albert Einstein College of Medicine, noted, "Centenarians have a longer health-span and a compression of morbidity rooted in their genetics that slows their aging. Several drugs have been developed in part from data collected from the initial studies (Merck and Ionis). This is an ongoing project, and the team has been working together to prove the concept for this accelerated phase." Jan Vijg, Ph.D., also of Albert Einstein College of Medicine, added, "Pinpointing the genetic signatures that drive longevity is one of the greatest challenges in modern science. Working with Matter Bio to conduct comprehensive multi-omics analysis brings us closer than ever to unraveling these complexities." "Joining forces with Matter Bio will help transition fundamental discoveries in aging research into real-world gene therapies," said Vera Gorbunova, Ph.D., of the University of Rochester. "I'm excited about the potential to address the root causes of aging rather than simply tackling diseases after they occur." This ambitious initiative represents a major leap forward in actionable longevity science - with the potential to reshape the future of medicine and public health for generations to come. About Matter Bio Matter Bio is a biotechnology company at the forefront of longevity science, committed to extending human healthspan by enhancing genomic resilience and unlocking the genetic keys to healthy aging. Our platform harnesses naturally occurring DNA stability variants and delivers them to human cells to dramatically enhance cellular longevity. When cancer is already present, Matter is delivering engineered bacteria to find and kill tumor cells and these efforts are now entering human clinical trials. Through partnerships with leading scientists and institutions, Matter Bio is laying the groundwork for the next generation of preventive healthcare solutions. For more information, please visit SOURCE: Matter Bio press release
The Sun
21-04-2025
- Health
- The Sun
New ‘Diabetes type 5' discovered by scientists who say it's ‘vastly undiagnosed' – do you have the signs?
A NEW form of diabetes linked to malnutrition, not obesity, has been officially recognised. Named Type 5 diabetes, the disease is estimated to affect 25million people worldwide. It mainly strikes malnourished, lean teens and young adults in low and middle-income countries. The International Diabetes Federation (IDF) voted to classify the condition previously known as Maturity Onset Diabetes of the Young (MODY) at its World Diabetes Congress in Bangkok on April 8th. 'It has historically been vastly underdiagnosed and poorly understood,' said Professor Meredith Hawkins of Albert Einstein College of Medicine, said. 'The IDF's recognition of it as 'Type 5 diabetes' is an important step toward raising awareness of a health problem that is so devastating to so many people," she added. Globally, around 830 million adults are living with diabetes, mostly Type 1 and Type 2, according to a 2022 study. Both types affect the body's ability to control blood sugar levels. In Type 1 diabetes, the body can't produce insulin - a hormone that helps move sugar from the blood into cells for energy. This causes high blood sugar, which can damage organs. In Type 2 diabetes, the body still makes insulin but becomes resistant to it, so sugar stays in the blood instead of entering the cells. Over time, this also leads to high blood sugar levels. Type 5 diabetes is different. It's caused by malnutrition, which leads to low insulin production. The leaves the body unable to make enough insulin to manage blood sugar properly. It's not due to a total lack of insulin like Type 1, or insulin resistance like Type 2 - rather the body doesn't produce enough, often because of poor nutrition. 40 Day Health Challenge GP Dr Sumi Dunne on signs and symptoms of diabetes to watch out for Unlike Types 1 and 2, Type 5 is also usually inherited. If a parent carries the gene, their child has a 50 per cent chance of developing it, as the gene makes them more vulnerable to the condition. Type 5 diabetes typically appears in early teens or 20s, especially in young men in Asia and Africa with a body mass index (BMI) of 19. A healthy BMI is between 18 and 24.9, suggesting that those with Type 5 diabetes tend to be on the thinner side of healthy. Professor Nihal Thomas, of Christian Medical College in India, told The Indian Express: 'The disease causes pancreatic beta cells to function abnormally, which leads to insufficient production of insulin. "Due to the lack of formal recognition, this condition has been understudied and misdiagnosed.' Doctors often mistake it for Type 1 diabetes - but giving insulin can be dangerous, Prof Hawkins told Medscape Medical News. 'Malnutrition-related diabetes is more common than tuberculosis and nearly as common as HIV/AIDS,' Prof Hawkins said. 'But the lack of an official name has hindered efforts to diagnose patients or find effective therapies.' She first heard about the condition in 2005 when doctors from several countries described a strange form of diabetes. "The patients were young and thin, which suggested that they had Type 1 diabetes, which can be managed with insulin injections to regulate blood sugar levels. "But insulin didn't help these patients and in some cases caused dangerously low blood sugar," she said, according to Medical Express. The patients did not seem to have Type 2 diabetes either, as it is typically associated with obesity, which the doctor said "was very confusing." In 2010, Prof Hawkins founded Einstein's Global Diabetes Institute. More than a decade later in 2022, Prof Hawkins and her colleagues at the Christian Medical College demonstrated that this form of diabetes was fundamentally different from Type 1 and 2. She said people with Type 5 diabetes have a profound defect in the capacity to secrete insulin which wasn't recognised before. This means their bodies can't properly absorb and store nutrients, especially sugar and fat to put on any weight, or store muscle. As a result, they often stay very thin, even if they're eating enough. 'This finding has revolutionised how we think about this condition and how we should treat it," she said. But there's still no standard treatment, with many patients dying within a year of diagnosis. Prof Hawkins said diets high in protein and low in carbohydrates, along with targeted micronutrients, may help. But she warned: 'This needs to be carefully studied now that there is global will and an official mandate from [IDF] to do so.'
