Latest news with #AmericanAcademyofOrthopaedicSurgeons
Yahoo
30-05-2025
- Business
- Yahoo
Moximed announces treatment of first subject in trial of knee system
Moximed has announced the treatment of the first subject in the multi-centre MOTION randomised controlled trial (RCT) assessing its MISHA knee system against non-surgical treatment in individuals with medial knee osteoarthritis (OA). This prospective trial is designed to assess the benefits of the MISHA system compared with non-surgical treatment options endorsed by the American Academy of Orthopaedic Surgeons (AAOS) Clinical Practice Guidelines. These include physical therapy, weight management, physical conditioning, intra-articular injections, assistive devices, and various medications. At least 100 participants will be randomised in the trial, which is currently enrolling at approximately ten sites across the US. Enrolment locations include RUSH University Medical Center, NYU Langone Health, and Scripps Health. The primary endpoint of the study is the improvement in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score. In 2023, the MISHA knee system secured marketing authorisation from the US Food and Drug Administration (FDA). The system claims to have demonstrated superiority to high tibial osteotomy (HTO) in two years after the operation. It is specifically designed for those who have not found relief from previous treatments and are either ineligible for or unwilling to undergo joint replacement surgery. Knee OA is said to arise when the joint's natural shock absorbers, the cartilage and meniscus, fail to cushion it, resulting in chronic pain and restricted activity. Moximed noted that as the first implantable shock absorber for the knee, the MISHA system minimises the load on the joint while walking, potentially alleviating pain, preserving joint function, and delaying the need for replacement surgery. The device is implanted on the medial knee and is engineered to move in harmony with the joint, decreasing 30% of the peak force exerted on the knee during walking. Moximed CEO and president Christopher Gleason said: 'Knee OA patients across the country are looking for an effective and less invasive treatment option without activity restrictions. 'The growing commercial adoption of the MISHA knee system reflects the confidence that physicians and patients have in this breakthrough treatment.' "Moximed announces treatment of first subject in trial of knee system" was originally created and published by Medical Device Network, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
NDTV
06-05-2025
- Health
- NDTV
Tips For Students And Working Professionals To Prevent Carpal Tunnel
In today's digital world, prolonged typing, texting, and repetitive hand movements have made carpal tunnel syndrome (CTS) a growing concern, especially among students and working professionals. CTS occurs when the median nerve, which runs through the carpal tunnel in your wrist, becomes compressed. Symptoms like tingling, numbness, and weakness in the hand and fingers can impact daily functioning. According to the National Institute of Neurological Disorders and Stroke (NINDS), early preventive measures and ergonomic awareness can significantly reduce your risk. Whether you're working on a laptop or writing notes for hours, here are practical tips to protect your hands and wrists. Consistent strain can lead to long-term wrist damage Carpal tunnel syndrome doesn't develop overnight, it builds over time due to repetitive stress on the wrist. Poor posture, improper hand positioning, and lack of breaks can all contribute. Students and professionals are particularly vulnerable due to extended hours at computers and smartphones. However, the good news is that small daily changes can prevent the problem altogether. 1. Maintain proper wrist posture Keep your wrists in a neutral, straight position when typing or writing. Avoid bending them up or down. An ergonomic keyboard or wrist pad can help maintain the right alignment, reducing pressure on the median nerve. 2. Take frequent breaks Follow the 20-20-20 rule not just for your eyes, but your hands too. Every 20 minutes, pause for 20 seconds and stretch or shake out your hands. This reduces strain and improves circulation. 3. Use correct typing techniques Type lightly and avoid pounding the keys. Keep your hands floating above the keyboard, with fingers relaxed. Avoid resting your wrists on hard surfaces while working, which can compress the nerves. 4. Stretch and strengthen your hands Simple exercises like wrist circles, finger stretches, or squeezing a stress ball improve flexibility and reduce stiffness. According to the American Academy of Orthopaedic Surgeons (AAOS), regular stretching can prevent carpal tunnel syndrome symptoms in high-risk individuals. 5. Adjust your workstation ergonomically Ensure your screen is at eye level, chair height supports your lower back, and your elbows are at a 90-degree angle when typing. Poor desk setup is a key contributor to wrist and shoulder strain. 6. Limit continuous smartphone use Prolonged texting or gaming on mobile phones can stress your thumb and wrist. Use voice-to-text features when possible and take breaks from scrolling. Use both hands while typing on phones to distribute the load evenly. 7. Stay physically active A sedentary lifestyle worsens carpal tunnel syndrome symptoms. General physical activity promotes circulation, reduces inflammation, and helps maintain a healthy weight, all factors that indirectly benefit wrist health. 8. Be mindful of early warning signs Tingling, numbness, or pain in your thumb, index, or middle fingers, especially at night, can indicate early carpal tunnel syndrome. Don't ignore these signs. Early intervention can prevent worsening and the need for surgery. 9. Wear a wrist splint at night if needed For those already experiencing mild symptoms, wearing a splint can keep the wrist in a neutral position while sleeping. This helps reduce night-time numbness and discomfort. 10. Stay hydrated and maintain a balanced diet Inflammation can worsen nerve compression. A diet rich in anti-inflammatory foods like leafy greens, berries, turmeric, and omega-3s may help. Stay well-hydrated to keep tendons and joints lubricated. Prevention is better than treatment Carpal tunnel syndrome can be painful and even disabling if left unchecked. Students and professionals should adopt a proactive approach by integrating ergonomic habits, movement, and hand care into their daily routines. As per the National Health Service (NHS UK), early awareness and prevention are key to avoiding chronic wrist conditions. Disclaimer: This content including advice provides generic information only. It is in no way a substitute for a qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.
Time Business News
02-05-2025
- Health
- Time Business News
New Systems Approach For Hip and Knee Pain: Fix the Root Cause, Not Just the Symptoms
Hip and knee pain are among the leading causes of mobility loss, chronic discomfort, and decreased quality of life. Although often addressed separately, these two joints are deeply interconnected — sharing the femur bone and functioning together as part of a complex biomechanical chain. Dysfunction in one joint often destabilizes the other, making a combined approach essential for effective treatment and prevention. 'In my clinical experience, treating hip and knee pain separately often misses the underlying cause of chronic dysfunction,' says Rick Olderman, MSPT. Olderman, an orthopedic physical therapist with more than two decades of experience, has specialized in identifying hidden movement patterns that drive persistent musculoskeletal pain. His work emphasizes restoring natural biomechanics to address pain at its root, rather than merely treating its symptoms. Understanding how the hip and knee interact — and how imbalances can lead to breakdown — is a crucial step toward regaining mobility, reducing pain, and maintaining long-term joint health. Hip and knee pain are closely linked through shared anatomy and movement patterns. Weak gluteal muscles and poor alignment increase joint stress and degeneration risks. Strengthening glutes and improving walking mechanics can significantly reduce joint pain. Ignoring conditions like Anterior Femoral Glide Syndrome (AFGS) can accelerate cartilage damage. Daily habits like avoiding locked knees and using targeted exercises protect joint health. Ignoring the interconnected nature of hip and knee mechanics can lead to progressive joint damage, reduced mobility, and a greater risk of osteoarthritis. Research from the American Academy of Orthopaedic Surgeons (AAOS) shows that addressing biomechanical factors early can significantly improve joint longevity and function. Understanding movement patterns — and correcting them — empowers individuals to move better, hurt less, and maintain independence longer. How the Hip and Knee Joints Work The pelvis is formed from two ilia and the sacrum. Each ilium houses a hip socket called the acetabulum, forming a ball-and-socket joint with the head of the femur (thigh bone). Surrounding the acetabulum is the labrum — a fibrocartilaginous ring that deepens the socket and stabilizes the femoral head through negative air pressure. The gluteus maximus, the body's largest muscle, is critical for maintaining hip stability and controlling movement forces through the joint. At the opposite end of the femur, the knee joint forms where the femur meets the tibia (shin bone). The femoral end divides into two lobes, called condyles, which enable natural rotation during movement. Key structures supporting the knee joint include: The meniscus , which cushions and stabilizes the joint. , which cushions and stabilizes the joint. The anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL), which guide knee motion and prevent instability. Hip pain often stems from a combination of joint dysfunction, muscular imbalances, and structural irregularities. A major contributor is Anterior Femoral Glide Syndrome (AFGS) — a condition where poor gluteal control allows the femoral head to migrate forward within the hip socket. Olderman explains: 'When the glutes don't stabilize the femur correctly, the thigh bone behaves like a washing machine out of balance — creating friction, irritation, and eventual damage inside the hip joint.' Common consequences of AFGS include: Groin pain (often diagnosed as femoral acetabular impingement [FAI] ) ) Hip bursitis , caused by bursal irritation , caused by bursal irritation Labral tears , due to shearing stresses on the labrum , due to shearing stresses on the labrum Piriformis syndrome , leading to sciatic nerve irritation , leading to sciatic nerve irritation Accelerated degeneration contributing to hip osteoarthritis Secondary lower back pain from pelvic instability Knee pain frequently develops when the thigh bone rotates inward excessively, increasing strain on the knee joint. Contributing factors include: Habitually locking the knees while standing or walking, straining cartilage, ligaments, and the popliteus muscle Weak gluteal strength, failing to stabilize femur positioning Structural predispositions such as femoral anteversion (an inward twist of the thigh bone) According to the Mayo Clinic, poor biomechanics — especially involving the hips and knees — is a leading contributor to premature joint deterioration. The gluteus maximus is not just a powerful muscle; it acts as the body's steering system for the hips and knees. Without strong glutes, both joints are left vulnerable to abnormal forces. As Olderman notes: 'The glutes control not just strength, but alignment. When they weaken, the risk of breakdown accelerates.' Recommended Exercise: The Butt Pump Position yourself on your elbows and knees (or lean against a counter). Lift one leg behind you until you feel the buttock muscles engage. Slightly rotate the lifted knee outward to enhance gluteal activation. Pump the lifted leg up and down about an inch, focusing solely on activating the glutes. Perform 2 sets of 30 repetitions, 1–2 times per day. This exercise helps realign the femoral head, stabilize the pelvis, and reduce rotational stress at the knee. Tension in the popliteus muscle, located behind the knee, can lead to joint compression and stiffness, particularly when the knees are habitually locked. Steps to relieve popliteus strain: Stay mindful to avoid locking your knees when standing or walking. when standing or walking. Incorporate regular massage therapy targeting the popliteus muscle to release tension and improve knee mobility. Walking can either support healing or contribute to joint strain, depending on gait mechanics. Supportive walking: Activating the glutes stabilizes the hips and knees and promotes healthier movement patterns. Activating the glutes stabilizes the hips and knees and promotes healthier movement patterns. Strainful walking: Over-striding, poor posture, or locked knees increase stress and dysfunction in both joints. Monitoring posture, stride, and muscle engagement while walking can turn this everyday activity into a powerful tool for joint health. Hip and knee pain rarely exists in isolation. They are often symptoms of broader movement dysfunctions involving the back, pelvis, and lower limbs. For a deeper exploration of how seemingly separate pains are linked, readers can refer to Rick Olderman's book, Pain Patterns: Why You Are in Pain and How to Stop It . The book offers insights into movement-based solutions for chronic musculoskeletal problems. You can also visit his website, for free access to a masterclass video on pain patterns. Rick Olderman, MSPT, is an orthopedic physical therapist, author, and clinical expert specializing in the movement-based treatment of chronic musculoskeletal pain. His work bridges the gap between traditional therapy and long-term pain resolution by focusing on biomechanical correction. Disclaimer: This article is for educational purposes only and is not a substitute for professional medical advice. Please consult a qualified healthcare provider for evaluation and treatment of persistent pain. TIME BUSINESS NEWS
Globe and Mail
11-03-2025
- Business
- Globe and Mail
Joint Replacement Devices Market to Hit USD 31.09 Billion by 2030 with 4.8% CAGR
Browse 333 market data Tables and 63 Figures spread through 375 Pages and in-depth TOC on "Joint Replacement Devices Market by Product (Knee, Hip, Shoulder, Ankle, Elbow, Wrist, Bone Grafts), Surgery (Total, Partial, Revision), Type(Cemented, Cementless, Hybrid), Procedure type, End user (Hospitals, ASC, Trauma, Clinic) - Global Forecast to 2030 The global joint replacement devices market, valued at US$22.50 billion in 2023, is forecasted to grow at a robust CAGR of 4.8%, reaching US$23.42 billion in 2024 and an impressive US$31.09 billion by 2030. The main factor driving this market is the increasing rate of orthopaedic disorders, especially among the baby boomer population. Additionally, the market is growing due to various initiatives by major companies, including the introduction of new joint replacement devices. The rising demand for joint replacement devices is further supported by the growing number of hospitals and surgical centers and improved healthcare access in developing countries. The key players in this market focus on expanding their reach in emerging economies by applying various strategies such as collaborations and agreements, further driving market growth. Browse in-depth TOC on " Joint Replacement Devices Market" 333 - Tables 63 - Figures 375 - Pages The joint replacement devices market is segmented based on product into knee replacement devices, hip replacement devices, shoulder replacement devices, elbow replacement devices, ankle implants, wrist replacement devices, other replacement devices, and bone graft substitutes. The knee replacement devices segment is expected to hold major share of the market in 2023. The increase in number of knee replacement procedures and the increasing incidence of knee osteoarthritis is driving the growth of this segment. Each year more than 70,000 knee replacement procedures are performed in England and wales each year (Source: NHS). In the year 2022, the revision and primary knee and hip arthroplasty procedures performed were 3,149,042 from 2012 to 2022 i.e., 23% growth in procedural cases (Source: American Academy of Orthopaedic Surgeons). By surgery type, the joint replacement devices market is segmented into total replacement, partial replacement, and revision replacement. In 2023, the total replacement segment held a significant share of the market 2023. The growth in this segment is driven by the increasing number joint replacement surgeries such as hip and knee replacement and increasing incidence of osteoarthritis. In case of total replacement, the damaged cartilage along with the bone is replaced with an artificial implant that mimics the shape of the natural joint and help individual to carry out the day-to-day activities. By type, the joint replacement devices market is segmented into cemented fixation, cementless fixation, reverse hybrid fixation, and hybrid fixation. In the year 2023, the cemented fixation segment held largest share of the market. There are multiple factors attributing to the largest share of the segment such as enhanced bone fixation, improved stability of an implant in patient's body, and enhanced assistance drives the growth of the segment. Cemented fixation also enables the delivery of antibiotics at the targeted site, helps to reduce thigh pain, and enhances the survival of an implant. By technique, the joint replacement devices market is segmented into traditional surgery, minimally invasive surgery and computer assisted surgery. In 2023, the minimally invasive surgery held largest share in the global joint replacement devices market by technique. The factors contributing to its largest share are need for smaller incision, reduced pain, and increased awareness among individuals for early detection. Regarding end users, the joint replacement devices market is fragmented into hospitals & surgical centers and ambulatory care centers & trauma units, and orthopedic clinics. The major share of the market was contributed by hospitals & surgical centers segment in 2023. Consistent rise in new funding opportunities and increasing focus on research specifically in healthcare by various public and private organizations are fueling the segment growth. Furthermore, increasing number of hospitals and advanced surgical centers which are equipped with new and innovative surgical equipment support the growth of the segment. The joint replacement devices market is segmented by region into Europe, North America, Asia Pacific, Latin America, and Middle East & Africa. In 2023, North America region accounted for the major market share, followed by Europe and Asia Pacific. The significant share of North America in this market is attributed to the existence of major key players, change in lifestyle, increasing geriatric population, and rising prevalence of bone disorders. Furthermore, factors such as increasing healthcare expenditure and growing number of various joint replacement treatments due to increase in awareness among common people coupled with early detection supports the market growth in this region. The joint replacement devices market is consolidated. As of 2023, the key players operating in the global joint replacement devices market are Zimmer Biomet Holdings, Inc. (US), Stryker Corporation (US), Johnson & Johnson MedTech (US), Smith+Nephew (UK), (Germany). In 2023, Zimmer Biomet Holdings, Inc. (US), Stryker Corporation (US), Johnson & Johnson MedTech (US) held a significant share of the joint replacement devices market. These players have adopted key strategies such as acquisitions, partnerships, and expansions in the last four to five years that contributed to their position in the joint replacement devices market. Stryker Corporation (US) Stryker Corporation is among the leading companies in the global joint replacement devices market. The organization has a robust presence in the global market including regions like Europe, North America, the Middle East, Africa, and the Asia Pacific. The company its brand presence in more than 75 countries across the global market. The company provides joint replacement devices through its Orthopaedics & Spine division business segment. The company focuses on improving its product portfolio and making new additions to the same. It focuses on innovation and offers unique products to sustain its leading position in the market. The company also focuses on R&D and bring technologically advanced products in the market for its customers addressing their unmet needs. Zimmer Biomet Holdings, Inc. (US) Zimmer Biomet is one of the leading companies in the joint replacement devices market. It is involved in the manufacturing and marketing of a range of medical devices and related products in healthcare industry. The company offers joint replacement devices through its Knees, Hips, and S.E.T segments. The company holds a robust presence across multiple countries such as Germany, France, Italy, Switzerland, Spain, the UK, Japan, South Korea, China, Australia, New Zealand, Taiwan, India, Hong Kong, Thailand, Singapore, and Malaysia. Also, the company distributes its products across Central & Eastern Europe, Benelux, Nordic, and the Middle East & Africa. Zimmer Biomet maintains a strong product portfolio, has a robust brand value among joint replacement devices end users, and strong R&D capabilities. Johnson & Johnson MedTech (US) Johnson & Johnson MedTech is another major player operating in the joint replacement devices market. The company is involved in the manufacturing, R&D, and marketing of joint replacement devices and other healthcare products globally. It offers joint replacement devices under the MedTech business unit. The company is dedicated to offering technologically advanced products focused on enhancing clinical outcomes. The company made a collaboration with CrossRoads Extremity Systems (US) with an aim to improve orthopaedic care with new and innovative ideas, hoping to give patients enhanced health results. The company holds a remarkable market share in more than 60 countries across diverse territories such as Asia Pacific, North America, Middle East & Africa, and Europe. For more information, Inquire Now!
Globe and Mail
10-03-2025
- Business
- Globe and Mail
Smith+Nephew to highlight breakthrough Sports Medicine technologies for joint repair at AAOS 2025
Smith+Nephew (LSE:SN, NYSE:SNN), the global medical technology company, today announces it will showcase the latest advancements in Sports Medicine for joint repair at the American Academy of Orthopaedic Surgeons Annual Meeting in San Diego this week. Some of the highlighted technologies will include: Spatial Surgery Smith+Nephew continues to pioneer in Sports Medicine and is excited to introduce a new category called Spatial Surgery - a revolutionary new frontier in arthroscopic surgical innovation. This 510(k)-pending technology called the TESSA ◊ Spatial Surgery System (Tracking Enabled Spatial Surgery Assistant) plans to combine personalized operative planning with a real-time, tracking enabled device using advanced imaging and augmented reality guidance to assist a surgeon in decision making. Learn more at CARTIHEAL ◊ AGILI-C ◊ Cartilage Repair Implant Smith+Nephew's CARTIHEAL AGILI-C Cartilage Repair Implant is an FDA approved device that was previously granted breakthrough designation and is now evolving the cartilage repair landscape. The unique properties of the implant enable physicians to surgically treat patients that previously had no access to cartilage repair procedures. 1-3 In a large randomized controlled trial, when compared to the surgical standard of care, * the CARTIHEAL AGILI-C implant demonstrated: Proven clinical superiority: Patients treated with the CARTIHEAL AGILI-C Implant reported significantly better knee function, pain relief, and mobility improvements over a 4-year period. 1,4 ** Significantly lower risk of TKA or osteotomy: Patients' risk of additional knee reconstruction/realignment surgery at 4 years. 4 Different patient profiles – same great results: The scaffold treats a broad group of patients across age, lesion size, and presence of osteoarthritis while delivering clinically meaningful results. 1,4, ** The use of the CARTIHEAL AGILI-C Implant in the presence of osteoarthritis will be featured during OrthoDome at AAOS on Wednesday, March 12, from 11:16-11:31 am PST. You can learn more by visiting the CARTIHEAL AGILI-C webpage here. REGENETEN ◊ Bioinductive Implant The REGENETEN Bioinductive Implant is a scaffold made from highly purified type I collagen fibers and has changed the way surgeons treat tendon injuries for more than ten years. 5-8 Clinical studies in rotator cuff repair have demonstrated results that surpass the current standard of care: 3x reduction in the risk of re-tear in a randomized controlled trial versus standard repair alone augmenting repair of medium-to-large full-thickness tears (at 1-year). 9*** Accelerated recovery and return to activity when used as an isolated treatment (compared with takedown and suture anchor repair), 10,11 while leading to consistent tendon healing for partial-thickness tears. 9,12 Well established technique used in >150,000 patients, with a proprietary delivery and fixation system resulting in a 15-minute procedure. 9 In addition to continued value in rotator cuff repair, usage of the REGENETEN Implant continues to increase in tendons around the body, including those in the hip, knee, and foot & ankle, where surgeons recognize its potential to improve tendon healing. You can learn more by visiting the REGENETEN webpage here. To learn more about Smith+Nephew's Sports Medicine joint repair solutions and enabling technologies, please visit our booth (#3729) at the American Academy of Orthopaedic Surgeons Annual Meeting in San Diego March 11-13, 2025, or visit Media Enquiries Dave Snyder +1 (978) 749-1440 Smith+Nephew * Debridement or microfracture ** Over a 2- and 4-year follow-up *** Re-tear: 8.3% vs 25.8%; Relative risk=0.32 [95% Confidence Interval 0.13- 0.83]; p=0.0106. References Altschuler N, Zaslav KR, Di Matteo B, et al. Aragonite-Based Scaffold Versus Microfracture and Debridement for the Treatment of Knee Chondral and Osteochondral Lesions: Results of a Multicenter Randomized Controlled Trial. Am J Sports Med. 2023;51(4):957-967 Kon E, Di Matteo B, Verdonk P, et al. Aragonite-Based Scaffold for the Treatment of Joint Surface Lesions in Mild to Moderate Osteoarthritic Knees: Results of a 2-Year Multicenter Prospective Study. Am J Sports Med. 2021;49(3):588-598 Kon E, Filardo G, Shani J, et al. Osteochondral regeneration with a novel aragonite-hyaluronate biphasic scaffold: up to 12-month follow-up study in a goat model. J Orthop Surg Res. 2015;10:81 Conte P, Anzillotti G, Crawford DC, et al. Differential analysis of the impact of lesions' location on clinical and radiological outcomes after the implantation of a novel aragonite-based scaffold to treat knee cartilage defects. Int Orthop. 2024;48(12):3117-3126 Bokor DJ, et al. Muscles Ligaments Tendons J. 2016;6(1):16-25. Warren JR, et al. J Shoulder Elbow Surg. 2024;33(11):2515-2529 Bokor DJ, et al. Muscles Ligaments Tendons J. 2015;5(3):144-150. Smith+Nephew 2020 REGENETEN Collagen Implant Physical Characteristics. Internal Report Internal Report. 15009769 Ruiz Ibán MÁ, et al. Arthroscopy. 2024;40(6):1760-1773. Camacho Chacón JA, et al. J Shoulder Elbow Surg. 2024;33(9):1894-1904. Bushnell BD, et al. Orthop J Sports Med. 2021;9(8):23259671211027850. Schlegel TF, Abrams JS, Bushnell BD, Brock JL, Ho CP. Radiologic and clinical evaluation of a bioabsorbable collagen implant to treat partial-thickness tears: a prospective multicenter study. J Shoulder Elbow Surg. 2018 27(2):242-251 About Smith+Nephew Smith+Nephew is a portfolio medical technology business focused on the repair, regeneration and replacement of soft and hard tissue. We exist to restore people's bodies and their self-belief by using technology to take the limits off living. We call this purpose 'Life Unlimited'. Our 17,000 employees deliver this mission every day, making a difference to patients' lives through the excellence of our product portfolio, and the invention and application of new technologies across our three global business units of Orthopaedics, Sports Medicine & ENT and Advanced Wound Management. Founded in Hull, UK, in 1856, we now operate in around 100 countries, and generated annual sales of $5.8 billion in 2024. Smith+Nephew is a constituent of the FTSE100 (LSE:SN, NYSE:SNN). The terms 'Group' and 'Smith+Nephew' are used to refer to Smith & Nephew plc and its consolidated subsidiaries, unless the context requires otherwise. For more information about Smith+Nephew, please visit and follow us on X, LinkedIn, Instagram or Facebook. Forward-looking Statements This document may contain forward-looking statements that may or may not prove accurate. For example, statements regarding expected revenue growth and trading profit margins, market trends and our product pipeline are forward-looking statements. Phrases such as "aim", "plan", "intend", "anticipate", "well-placed", "believe", "estimate", "expect", "target", "consider" and similar expressions are generally intended to identify forward-looking statements. Forward-looking statements involve known and unknown risks, uncertainties and other important factors that could cause actual results to differ materially from what is expressed or implied by the statements. For Smith+Nephew, these factors include: conflicts in Europe and the Middle East, economic and financial conditions in the markets we serve, especially those affecting healthcare providers, payers and customers; price levels for established and innovative medical devices; developments in medical technology; regulatory approvals, reimbursement decisions or other government actions; product defects or recalls or other problems with quality management systems or failure to comply with related regulations; litigation relating to patent or other claims; legal and financial compliance risks and related investigative, remedial or enforcement actions; disruption to our supply chain or operations or those of our suppliers; competition for qualified personnel; strategic actions, including acquisitions and disposals, our success in performing due diligence, valuing and integrating acquired businesses; disruption that may result from transactions or other changes we make in our business plans or organisation to adapt to market developments; relationships with healthcare professionals; reliance on information technology and cybersecurity; disruptions due to natural disasters, weather and climate change related events; changes in customer and other stakeholder sustainability expectations; changes in taxation regulations; effects of foreign exchange volatility; and numerous other matters that affect us or our markets, including those of a political, economic, business, competitive or reputational nature. Please refer to the documents that Smith+Nephew has filed with the U.S. Securities and Exchange Commission under the U.S. Securities Exchange Act of 1934, as amended, including Smith+Nephew's most recent annual report on Form 20-F, which is available on the SEC's website at www. for a discussion of certain of these factors. Any forward-looking statement is based on information available to Smith+Nephew as of the date of the statement. All written or oral forward-looking statements attributable to Smith+Nephew are qualified by this caution. Smith+Nephew does not undertake any obligation to update or revise any forward-looking statement to reflect any change in circumstances or in Smith+Nephew's expectations.
