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Time of India
17-05-2025
- Health
- Time of India
Pune woman breaks femur while getting out of bed, doctors detect metabolic disorder
Pune: It was indeed a mystery for the doctors at a private hospital in the city. A 23-year-old woman had come in with a broken femur, the longest and strongest bone in the human body. The doctors first assumed it was a fall injury, but were taken aback when the woman said she had suffered the fracture while simply getting out of bed in the morning. The doctors called for a battery of tests and that's when they discovered that a rare metabolic disorder in her had caused calcium levels to drop, leaving the woman with brittle bones. The problem was in the neck, where the parathyroid gland regulates calcium metabolism and bone strength by secreting parathormone. In the woman's case, excessively high parathormone levels had depleted calcium from her bones. "Tests showing elevated blood calcium and parathormone levels pointed to an underlying metabolic disorder. As for her fracture, we performed an open reduction and stabilised the femur with screws," said Dr Rahul Salunkhe, the woman's treating doctor and head of orthopaedics at DPU Super Speciality Hospital in Pimpri. But doctors still suspected something deeper. The femur - because of its load-bearing nature - does not break so easily. The woman underwent a sonography of the neck and a CT scan, but the tests did not detect any enlargement of the parathyroid gland. "But further investigations with a parathyroid nuclear scan revealed an ectopic parathyroid adenoma, an extremely rare tumour located in the chest cavity. Such tumors account for just 1–2% of all parathyroid adenomas, which made this woman's case very rare," said Dr Anil Menon, head of the hospital's endocrinology department. The tumour had triggered the excess production of parathormone, which led to calcium depletion. The woman was referred to the oncology department where Dr Samir Gupta, head of surgical oncology, and team performed a video-assisted thoracoscopic (keyhole) surgery to remove the tumour. "The procedure uncovered the lesion embedded within the thymus gland, resting over the heart. The surgery was complex, but use of keyhole techniques ensured a quick recovery with minimal scarring," said Dr Gupta. The surgery, performed in Jan this year was a success, doctors said, and after a period of follow-ups, the patient was declared recovered. She was also put on supplemental calcium and Vitamin D therapy while doctors closely monitored her calcium levels. Dr Salunkhe from the orthopaedics department said such serious fractures, especially in young people, needed thorough investigations. He said: "These fractures may not only be indicative of underlying systemic diseases or bone pathology, but also demand timely intervention to restore function and prevent complications."


Zawya
05-03-2025
- Business
- Zawya
MENA sees increased M&A activity in 2024 with 701 deals totaling $92.3bln
Doha: According to the latest EY MENA M&A Insights 2024 report, the MENA region recorded a 3% rise in merger and acquisition (M&A) activity with 701 deals in 2024, compared to 679 deals in 2023. The total deal value in 2024 reached $92.3bn, indicating a 7% increase from the previous year. The GCC region accounted for the majority of dealswith580, amounting to $90bn. This expansion was largely fueled by substantial reforms in the capital markets, strategic policy changes and enhanced efforts to attract foreign investments. Cross-border deals were the major driver of M&A deals in the MENA region, accounting for 52%of the volume and 74% of the value. Brad Watson, EY MENA Strategy and Transactions Leader, says: 'In 2024, the MENA region witnessed positive developments in the M&A space with a y-o-y increase in activity as well as overall deal value. With companies actively seeking opportunities to grow and diversify their operations, cross-border deals were the major driver in terms of volume and value. The top five subsectors were insurance, asset management, real estate and hospitality, power and utilities, and technology – indicating a real interest in the innovative solutions that the MENA region can provide. In addition, there is a focus on strengthening regional relationships with Asian and European countries, enabled MENA countries to gain access to larger and growing markets.' Anil Menon, EY MENA Head of M&A and Equity Capital Markets Leader, says: 'In 2024, technology remained the most attractive sector for investors, accounting for 23% of total inbound and domestic deal volume. We're living through a productivity renaissance fueled by technology and AI, which will manifest in capital allocation and M&A.' 'The deal book (across sectors) for the fiscal year 2025 remains extremely strong and we expect to see continued portfolio momentum and interest in MENA-based assets.' Sovereign wealth funds (SWFs), such as the Abu Dhabi Investment Authority (ADIA) and Mubadala from the United Arab Emirates (UAE), as well as the Public Investment Fund (PIF) from the Kingdom of Saudi Arabia (KSA), continued to lead the deal activity in the region. Outbound deals contributed the largest share of M&A transaction value in 2024 accounting for61% of the total consolidated deal value, with 199transactions amounting to $ MENA region continues to be one of the most attractive destinations for foreign direct investors. © Dar Al Sharq Press, Printing and Distribution. All Rights Reserved. Provided by SyndiGate Media Inc. (