Latest news with #AnnetteRegan
Yahoo
10-05-2025
- Health
- Yahoo
Whooping cough is surging. Here's what you can do to protect yourself.
When you buy through links on our articles, Future and its syndication partners may earn a commission. Whooping cough, a bacterial infection that can be especially dangerous for babies and young children, is on the rise. Already in 2025 the U.S. has recorded 8,485 cases. That's compared with 4,266 cases during the same period in 2024. Like measles, which is also spreading at unprecedented levels, whooping cough, more formally known as pertussis, can be prevented by a safe and effective vaccine. But with anti-vaccine sentiment increasing and cuts to immunization services, vaccination rates for whooping cough over the past two years have declined in children. The Conversation asked epidemiologist Annette Regan to explain why pertussis has become so prevalent and how families can protect themselves from the disease. Pertussis is a vaccine-preventable disease caused by the bacterium Bordetella pertussis. Researchers in France first identified the B. pertussis bacterium in 1906. The first recorded epidemic of pertussis is thought to have occurred in Paris in 1578. Infection can cause an acute respiratory illness characterized by severe and spasmodic coughing spells. The classic symptom of pertussis is a "whoop" sound caused by someone trying to breath during a bad cough. Severe complications of pertussis include slowed or stopped breathing, pneumonia and seizures. The disease is most severe in young babies, although severe cases and deaths can also occur in older children and adults. Some doctors call pertussis "the 100-day cough" because symptoms can linger for weeks or even months. Related: Whooping cough outbreaks: Why is pertussis on the rise in several countries? The World Health Organization estimates that 24.1 million pertussis cases and 160,700 deaths occur worldwide in children under 5 each year. Pertussis is highly contagious. Upon exposure, 80% of people who have not been previously exposed to the bacterium or vaccinated against the disease will develop an infection. Fortunately, the disease is largely preventable with a safe and effective vaccine, which was first licensed in the U.S. in 1914. During the COVID-19 pandemic between 2020 and 2022, pertussis cases were lower than usual. This may have been a result of limited social contact due to social distancing, masking, school closures and lockdown measures, which reduced the spread of disease overall. In the past two years, however, pertussis cases have surpassed figures from before the pandemic. In 2024, local and state public health agencies reported 35,435 pertussis cases to the Centers for Disease Control and Prevention — a rate five times higher than the 7,063 cases reported in 2023 and nearly double the 18,617 cases reported in 2019 prior to the pandemic. Between October 2024 and April 2025, at least four people in the U.S. have died of pertussis: two infants, one school-age child and one adult. Although vaccines have resulted in a dramatic decline in pertussis infections in the U.S., incidence of the disease has been rising since the 1990s, except for a brief dip during the COVID-19 pandemic. Before the start of routine childhood vaccination for pertussis in 1947, its rates hovered between 100,000 and 200,000 cases per year. With vaccines, rates plunged under 50,000 annually by the late 1950s and under 10,000 per year in the late 1960s. They reached a low of 1,010 cases in 1976. Starting in the 1980s and 1990s, however, the U.S. and several other countries have been seeing a steady resurgence of pertussis cases, which have exceeded 10,000 cases in the U.S. every year from 2003 to 2019. They dropped again during the pandemic until last year's resurgence. There is no single explanation for why cases have been rising recently, but several factors probably contribute. First, pertussis naturally occurs in cyclic epidemics, peaking every two to five years. It is possible that the U.S. is headed into one of these peaks after a period of low activity between 2020 and 2022. However, some scientists have noted that the increase in cases is larger than what would be expected during a usual peak. Some scientists have noted that this apparent resurgence correlates with a change in the type of vaccine used in children. Until the 1990s, the pertussis vaccine contained whole, killed B. pertussis bacteria cells. Whole-cell vaccine can stimulate a long-lasting immune response, but it is also more likely to cause fever and other vaccine reactions in children. In the 1990s, national vaccine programs began to transition to a vaccine that contains purified components of the bacterial cell but not the whole cell. Some scientists now believe that although this partial-cell vaccine is less likely to cause high fevers in children, it provides protection for a shorter time. Immunity after whole-cell vaccination is thought to last 10-12 years compared with three to five years after the partial-cell vaccine. This means people may become susceptible to infection more quickly after vaccination. Vaccination rates are also not as high as they should be and have started falling in children since 2020. In the U.S., the percent of kindergartners who are up to date with recommended pertussis vaccines has declined from 95% during the 2019-20 school year to 92% in the 2023-24 school year. Even fewer adolescents receive a booster dose. Routine vaccination for children starting in infancy followed by booster doses in adolescents and adults can help keep immunity high. Public health experts recommend that children receive five doses of the pertussis vaccine. According to the recommendations, they should receive the first three doses at 2, 4 and 6 months of age, then two additional doses at 15 months and 4 years of age, with the aim of providing protection through early adolescence. Infants younger than 6 weeks are not old enough to get a pertussis vaccine but are at the greatest risk of severe illness from pertussis. Vaccination during pregnancy can offer protection from birth due to antibodies that pass from the mother to the developing fetus. Many countries, including the U.S., now recommend that women receive one dose of pertussis vaccine between the 27th and 36th week of every pregnancy to protect their babies. To maintain protection against pertussis after childhood, a booster dose of pertussis vaccine is recommended for adolescents at 11 to 12 years of age. The CDC recommends that all adults receive at least one booster dose. Because immunity declines over time, people who are in contact with infants and other high-risk groups, such as caregivers, parents and grandparents, may benefit from additional booster doses. When feasible, the CDC also recommends a booster dose for adults 65 years and older. Vaccine safety studies over the past 80 years have proven the pertussis vaccine to be safe. Around 20% to 40% of vaccinated infants experience local reactions, such as pain, redness and swelling at the vaccination site, and 3% to 5% of vaccinated infants experience a low-grade fever. More severe reactions are much less common and occur in fewer than 1% of vaccinated infants. RELATED STORIES —Measles has long-term health consequences for kids. Vaccines can prevent all of them. —Shingles vaccine may directly guard against dementia, study hints —'We're already on the precipice of disaster': Deadly measles outbreaks could explode across the US in the next 25 years if vaccinations fall, model predicts The vaccine is also highly effective: For the first year after receiving all five doses of the pertussis vaccine, 98% of children are protected from pertussis. Five years after the fifth dose, 65% of vaccinated children remain protected. Booster vaccination during adolescence protects 74% of teens against pertussis, and booster vaccination during pregnancy protects 91% to 94% of immunized babies against hospitalization due to pertussis. Families can talk to their regular health care providers about whether a pertussis vaccine is needed for their child, themselves or other family members. This edited article is republished from The Conversation under a Creative Commons license. Read the original article.
Yahoo
30-04-2025
- Health
- Yahoo
Why Whooping Cough Is Making a Comeback
Whooping cough, a bacterial infection that can be especially dangerous for babies and young children, is on the rise. Already in 2025 the U.S. has recorded 8,485 cases. That's compared with 4,266 cases during the same period in 2024. Like measles, which is also spreading at unprecedented levels, whooping cough, more formally known as pertussis, can be prevented by a safe and effective vaccine. But with anti-vaccine sentiment increasing and cuts to immunization services, vaccination rates for whooping cough over the past two years have declined in children. The Conversation asked epidemiologist Annette Regan to explain why pertussis has become so prevalent and how families can protect themselves from the disease. Pertussis is a vaccine-preventable disease caused by the bacterium Bordetella pertussis. Researchers in France first identified the B. pertussis bacterium in 1906. The first recorded epidemic of pertussis is thought to have occurred in Paris in 1578. Infection can cause an acute respiratory illness characterized by severe and spasmodic coughing spells. The classic symptom of pertussis is a 'whoop' sound caused by someone trying to breath during a bad cough. Severe complications of pertussis include slowed or stopped breathing, pneumonia and seizures. The disease is most severe in young babies, although severe cases and deaths can also occur in older children and adults. Some doctors call pertussis 'the 100-day cough' because symptoms can linger for weeks or even months. The World Health Organization estimates that 24.1 million pertussis cases and 160,700 deaths occur worldwide in children under 5 each year. Pertussis is highly contagious. Upon exposure, 80 percent of people who have not been previously exposed to the bacterium or vaccinated against the disease will develop an infection. Fortunately, the disease is largely preventable with a safe and effective vaccine, which was first licensed in the U.S. in 1914. During the COVID-19 pandemic between 2020 and 2022, pertussis cases were lower than usual. This may have been a result of limited social contact due to social distancing, masking, school closures, and lockdown measures, which reduced the spread of disease overall. In the past two years, however, pertussis cases have surpassed figures from before the pandemic. In 2024, local and state public health agencies reported 35,435 pertussis cases to the Centers for Disease Control and Prevention — a rate five times higher than the 7,063 cases reported in 2023 and nearly double the 18,617 cases reported in 2019 prior to the pandemic. Between October 2024 and April 2025, at least four people in the U.S. have died of pertussis: two infants, one school-age child, and one adult. Although vaccines have resulted in a dramatic decline in pertussis infections in the U.S., incidence of the disease has been rising since the 1990s, except for a brief dip during the COVID-19 pandemic. Before the start of routine childhood vaccination for pertussis in 1947, its rates hovered between 100,000 and 200,000 cases per year. With vaccines, rates plunged under 50,000 annually by the late 1950s and under 10,000 per year in the late 1960s. They reached a low of 1,010 cases in 1976. Starting in the 1980s and 1990s, however, the U.S. and several other countries have been seeing a steady resurgence of pertussis cases, which have exceeded 10,000 cases in the U.S. every year from 2003 to 2019. They dropped again during the pandemic until last year's resurgence. There's no single explanation for why cases have been rising recently, but several factors probably contribute. First, pertussis naturally occurs in cyclic epidemics, peaking every two to five years. It's possible that the U.S. is headed into one of these peaks, after a period of low activity between 2020 and 2022. However, some scientists have noted that the increase in cases is larger than what would be expected during a usual peak. Some scientists have noted that this apparent resurgence correlates with a change in the type of vaccine used in children. Until the 1990s, the pertussis vaccine contained whole, killed B. pertussis bacteria cells. Whole-cell vaccine can stimulate a long-lasting immune response, but is also more likely to cause fever and other vaccine reactions in children. In the 1990s, national vaccine programs began to transition to a vaccine that contains purified components of the bacterial cell but not the whole cell. Some scientists now believe that although this partial-cell vaccine is less likely to cause high fevers in children, it provides protection for a shorter time. Immunity after whole-cell vaccination is thought to last 10-12 years compared with three to five years after the partial-cell vaccine. This means people may become susceptible to infection more quickly after vaccination. Vaccination rates are also not as high as they should be, and have started falling among children since 2020. In the U.S., the percent of kindergartners who are up to date with recommended pertussis vaccines has declined from 95 percent during the 2019-20 school year, to 92 percent in the 2023 to 24 school year. Even fewer adolescents receive a booster dose. Routine vaccination for children starting in infancy followed by booster doses in adolescents and adults can help keep immunity high. Public health experts recommend that children receive five doses of the pertussis vaccine. According to the recommendations, they should receive the first three doses at 2, 4, and 6 months of age, then two additional doses at 15 months and 4 years of age, with the aim of providing protection through early adolescence. Infants younger than 6 weeks aren't old enough to get a pertussis vaccine, but are at the greatest risk of severe illness from pertussis. Vaccination during pregnancy can offer protection from birth, due to antibodies that pass from the mother to the developing fetus. In fact, many countries, including the U.S., now recommend that women receive one dose of pertussis vaccine between the 27th and 36th week of every pregnancy to protect their babies. To maintain protection against pertussis after childhood, a booster dose of pertussis vaccine is recommended for adolescents at 11 to 12 years of age. The CDC recommends that all adults receive at least one booster dose. Because immunity declines over time, people who are in contact with infants and other high-risk groups — such as caregivers, parents, and grandparents — may benefit from additional booster doses. When feasible, the CDC also recommends a booster dose for adults 65 years and older. Vaccine-safety studies over the past 80 years have proven the pertussis vaccine to be safe. Around 20 percent to 40 percent of vaccinated infants experience local reactions — such as pain, redness, and swelling at the vaccination site — and 3 percent to 5 percent of vaccinated infants experience a low-grade fever. More severe reactions are much less common, and occur in fewer than 1 percent of vaccinated infants. The vaccine is also highly effective: For the first year after receiving all five doses of the pertussis vaccine, 98% of children are protected from pertussis. Five years after the fifth dose, 65 percent of vaccinated children remain protected. Booster vaccination during adolescence protects 74 percent of teens against pertussis, and booster vaccination during pregnancy protects 91 percent to 94 percent of immunized babies against hospitalization due to pertussis. Families can talk to their regular health care providers about whether a pertussis vaccine is needed for their child, themselves or other family members. This article is republished from The Conversation under a Creative Commons license. Read the original article. The post Why Whooping Cough Is Making a Comeback appeared first on Katie Couric Media.
Yahoo
29-04-2025
- Health
- Yahoo
Whooping cough is making a comeback, but the vaccine provides powerful protection
Whooping cough, a bacterial infection that can be especially dangerous for babies and young children, is on the rise. Already in 2025 the U.S. has recorded 8,485 cases. That's compared with 4,266 cases during the same period in 2024. Like measles, which is also spreading at unprecedented levels, whooping cough, more formally known as pertussis, can be prevented by a safe and effective vaccine. But with anti-vaccine sentiment increasing and cuts to immunization services, vaccination rates for whooping cough over the past two years have declined in children. The Conversation asked epidemiologist Annette Regan to explain why pertussis has become so prevalent and how families can protect themselves from the disease. Pertussis is a vaccine-preventable disease caused by the bacterium Bordetella pertussis. Researchers in France first identified the B. pertussis bacterium in 1906. The first recorded epidemic of pertussis is thought to have occurred in Paris in 1578. Infection can cause an acute respiratory illness characterized by severe and spasmodic coughing spells. The classic symptom of pertussis is a 'whoop' sound caused by someone trying to breath during a bad cough. Severe complications of pertussis include slowed or stopped breathing, pneumonia and seizures. The disease is most severe in young babies, although severe cases and deaths can also occur in older children and adults. Some doctors call pertussis 'the 100-day cough' because symptoms can linger for weeks or even months. The World Health Organization estimates that 24.1 million pertussis cases and 160,700 deaths occur worldwide in children under 5 each year. Pertussis is highly contagious. Upon exposure, 80% of people who have not been previously exposed to the bacterium or vaccinated against the disease will develop an infection. Fortunately, the disease is largely preventable with a safe and effective vaccine, which was first licensed in the U.S. in 1914. During the COVID-19 pandemic between 2020 and 2022, pertussis cases were lower than usual. This may have been a result of limited social contact due to social distancing, masking, school closures and lockdown measures, which reduced the spread of disease overall. In the past two years, however, pertussis cases have surpassed figures from before the pandemic. In 2024, local and state public health agencies reported 35,435 pertussis cases to the Centers for Disease Control and Prevention – a rate five times higher than the 7,063 cases reported in 2023 and nearly double the 18,617 cases reported in 2019 prior to the pandemic. Between October 2024 and April 2025, at least four people in the U.S. have died of pertussis: two infants, one school-age child and one adult. Although vaccines have resulted in a dramatic decline in pertussis infections in the U.S., incidence of the disease has been rising since the 1990s, except for a brief dip during the COVID-19 pandemic. Before the start of routine childhood vaccination for pertussis in 1947, its rates hovered between 100,000 and 200,000 cases per year. With vaccines, rates plunged under 50,000 annually by the late 1950s and under 10,000 per year in the late 1960s. They reached a low of 1,010 cases in 1976. Starting in the 1980s and 1990s, however, the U.S. and several other countries have been seeing a steady resurgence of pertussis cases, which have exceeded 10,000 cases in the U.S. every year from 2003 to 2019. They dropped again during the pandemic until last year's resurgence. There is no single explanation for why cases have been rising recently, but several factors probably contribute. First, pertussis naturally occurs in cyclic epidemics, peaking every two to five years. It is possible that the U.S. is headed into one of these peaks after a period of low activity between 2020 and 2022. However, some scientists have noted that the increase in cases is larger than what would be expected during a usual peak. Some scientists have noted that this apparent resurgence correlates with a change in the type of vaccine used in children. Until the 1990s, the pertussis vaccine contained whole, killed B. pertussis bacteria cells. Whole-cell vaccine can stimulate a long-lasting immune response, but it is also more likely to cause fever and other vaccine reactions in children. In the 1990s, national vaccine programs began to transition to a vaccine that contains purified components of the bacterial cell but not the whole cell. Some scientists now believe that although this partial-cell vaccine is less likely to cause high fevers in children, it provides protection for a shorter time. Immunity after whole-cell vaccination is thought to last 10-12 years compared with three to five years after the partial-cell vaccine. This means people may become susceptible to infection more quickly after vaccination. Vaccination rates are also not as high as they should be and have started falling in children since 2020. In the U.S., the percent of kindergartners who are up to date with recommended pertussis vaccines has declined from 95% during the 2019-20 school year to 92% in the 2023-24 school year. Even fewer adolescents receive a booster dose. Routine vaccination for children starting in infancy followed by booster doses in adolescents and adults can help keep immunity high. Public health experts recommend that children receive five doses of the pertussis vaccine. According to the recommendations, they should receive the first three doses at 2, 4 and 6 months of age, then two additional doses at 15 months and 4 years of age, with the aim of providing protection through early adolescence. Infants younger than 6 weeks are not old enough to get a pertussis vaccine but are at the greatest risk of severe illness from pertussis. Vaccination during pregnancy can offer protection from birth due to antibodies that pass from the mother to the developing fetus. Many countries, including the U.S., now recommend that women receive one dose of pertussis vaccine between the 27th and 36th week of every pregnancy to protect their babies. To maintain protection against pertussis after childhood, a booster dose of pertussis vaccine is recommended for adolescents at 11 to 12 years of age. The CDC recommends that all adults receive at least one booster dose. Because immunity declines over time, people who are in contact with infants and other high-risk groups, such as caregivers, parents and grandparents, may benefit from additional booster doses. When feasible, the CDC also recommends a booster dose for adults 65 years and older. Vaccine safety studies over the past 80 years have proven the pertussis vaccine to be safe. Around 20% to 40% of vaccinated infants experience local reactions, such as pain, redness and swelling at the vaccination site, and 3% to 5% of vaccinated infants experience a low-grade fever. More severe reactions are much less common and occur in fewer than 1% of vaccinated infants. The vaccine is also highly effective: For the first year after receiving all five doses of the pertussis vaccine, 98% of children are protected from pertussis. Five years after the fifth dose, 65% of vaccinated children remain protected. Booster vaccination during adolescence protects 74% of teens against pertussis, and booster vaccination during pregnancy protects 91% to 94% of immunized babies against hospitalization due to pertussis. Families can talk to their regular health care providers about whether a pertussis vaccine is needed for their child, themselves or other family members. This article is republished from The Conversation, a nonprofit, independent news organization bringing you facts and trustworthy analysis to help you make sense of our complex world. It was written by: Annette Regan, University of California, Los Angeles Read more: Measles cases are on the rise − here's how to make sure you're protected FDA's greenlighting of maternal RSV vaccine represents a major step forward in protecting young babies against the virus A nagging cough can hang on for weeks or months following a respiratory illness – and there is precious little you can do about it Annette Regan receives funding from the National Institutes of Health, the US Centers for Disease Control and Prevention, and the Global Vaccine Data Network.
Yahoo
28-02-2025
- Health
- Yahoo
As flu cases break records this year, vaccine rates are declining, particularly for children and 65+ adults
In February 2025, flu rates spiked to the highest levels seen in at least 15 years, with flu outpacing COVID-19 infections and hospitalizations for the first time since the beginning of the COVID-19 pandemic. The Centers for Disease Control and Prevention has classified this flu season as having 'high' severity across the U.S. The Conversation asked epidemiologist Annette Regan to explain why this flu season is different from last year's and what people can do to help reduce the spread. Beginning in late January and extending through February 2025, flu hospitalizations have been higher than any other week since before 2009. Most flu cases appear to be from influenza A strains, with a split between influenza A/H3N2 and influenza A/H1N1. These are two different subtypes of the influenza A virus. Researchers believe that historically seasons that are predominated by influenza A/H3N2 infections tend to be more severe, but infections from influenza A/H1N1 can still be very severe. This year's season is also peaking 'late' compared with the past three flu seasons, which peaked in early or late December. Unfortunately, there have been a number of deaths from flu too this season. Since Jan. 1, 2025, alone, over 4,000 people, including 68 children, have died from flu. While the number of deaths do not mark a record number, it shows that flu can be a serious illness, even in children. There are a number of factors behind any severe season, including poor community protection from low immunization rates and low natural immunity, virus characteristics, vaccine effectiveness and increased human contact via travel, office work or schools. Unfortunately, flu vaccination rates have declined since the COVID-19 pandemic. At the end of the 2023-24 flu season, 9.2 million fewer doses were administered in pharmacies and doctors' offices compared with an average year before the pandemic. In addition, since 2022, fewer and fewer doses of flu vaccine have been distributed by private manufacturers. Flu vaccination rates for adults have historically been in the 30% to 60% range, much lower than the recommended 70%. Before the COVID-19 pandemic, flu vaccination rates were increasing by around 1% to 2% every year. Flu vaccination rates began dropping after the COVID-19 pandemic, especially in higher-risk groups. Flu vaccination in children has dropped from 59% in 2019-20 to 46% in 2024-25. In adults 65 years and older, the group with the greatest risk of hospitalization and death, flu vaccination rates dropped from 52% in 2019-20 to 43% in 2024-25. Lower vaccination rates mean a greater portion of the population is not protected by vaccines. Data shows that vaccination reduces the risk of flu hospitalization. Even if a vaccinated person gets infected, they may be less likely to experience severe illness. As a result, low vaccination rates could contribute to higher flu severity this season. However, low vaccination rates are probably not the only reason for the high rates of flu this season. In previous severe seasons, genetic changes to the viruses have made them better at infecting people and more likely to cause severe illness. The effectiveness of annual flu vaccines varies depending on how well the vaccine matches the circulating virus. The effectiveness of vaccines ranges from 19% to 60% in any given season. In the 2023-24 flu season, the vaccine was 42% effective. Similarly, early 2024-25 data from the U.S. shows that the vaccine was 41% to 55% effective against flu hospitalizations in adults and 63% to 78% effective against flu hospitalizations in children. It's important to remember that people often incorrectly refer to 'the flu' when they have a common cold. Flu is caused only by the influenza virus, which tends to be more severe than common colds and more commonly causes a fever. Many of the signs and symptoms for flu, COVID-19 and other respiratory viruses are the same and can range from mild coldlike symptoms to pneumonia and respiratory distress. Common flu symptoms are fever, cough and fatigue, and may also include shortness of breath, a sore throat, nasal congestion, muscle aches and headache. Some symptoms, such as changes in or loss of taste and smell, are more common for COVID-19. For both COVID-19 and flu, the symptoms do not start until about one to four days after infection, and symptoms seem to last longer for COVID-19. The only way to know what virus is causing an infection is to test. This can be done using a rapid test, some of which now test for flu and COVID-19 together, or by seeing a doctor and getting tested using a nasal swab. There are prescription antiviral medications available to treat flu and COVID-19, but they need to be taken near the time that symptoms start. Some people are at high risk of severe flu and COVID-19, such as those who are immunosuppressed, have diabetes or have chronic heart or lung conditions. In these cases, it is important to seek early care and treatment from a health care professional. Some doctors will also prescribe via telehealth calls, which can help reduce the strain on doctors' offices, urgent care centers and emergency rooms when infection rates are high. There are a number of ways people can reduce their risk of getting or spreading flu. Since the flu season is still underway, it's not too late to get a flu vaccine. Even in seasons when the vaccine's effectiveness is low, it is likely to offer better protection compared with remaining unvaccinated. Handwashing and disinfecting high-traffic surfaces can help reduce contact with the flu virus. Taking efforts to avoid contact with sick people can also help, including wearing a mask when in health care facilities. Finally, remember to take care of yourself. Exercising, eating healthy and getting sufficient sleep all help support a healthy immune system, which can help reduce chances of infection. Those who have been diagnosed with flu or are experiencing flu-like symptoms should avoid contact with other people, especially in crowded spaces. Covering coughs and sneezes can help reduce the amount of virus that is spread. This article is republished from The Conversation, a nonprofit, independent news organization bringing you facts and trustworthy analysis to help you make sense of our complex world. It was written by: Annette Regan, University of California, Los Angeles Read more: CDC layoffs strike deeply at its ability to respond to the current flu, norovirus and measles outbreaks and other public health emergencies Bird flu flares up again in Michigan poultry – an infectious disease expert explains the risk to humans, chickens, cows and other animals How do you make a universal flu vaccine? A microbiologist explains the challenges, and how mRNA could offer a promising solution Annette Regan receives research funding from the National Institutes of Health, the US Centers for Disease Control and Prevention, and the Global Vaccine Data Network, and she is employed by the Department of Research & Evaluation at Kaiser Permanente Southern California.