Latest news with #BryanJohnson
Daily Mail
7 hours ago
- Health
- Daily Mail
Longevity experts reveal when humans will start living to 1,000... and it's sooner than you think
What if you could live forever, staying healthy and young for centuries? Scientists and tech pioneers now believe this dream could become reality. In Silicon Valley, entrepreneurs like Bryan Johnson follow intense routines, like his 'Blueprint' plan, to slow or reverse aging, and companies like Altos Labs are testing treatments that have already extended the lives of mice. Experts say we're on the cusp of technologies that could make immortality possible, and they've even set dates for when this future might arrive. Three visionaries stand out in this quest: futurologist Dr. Ian Pearson, Google 's Ray Kurzweil, and biomedical researcher Aubrey de Grey. Pearson predicts that by 2050, the wealthy will use advanced tech to live forever, perhaps by uploading their minds to computers or android bodies. Kurzweil believes that by 2029, artificial intelligence (AI) will match human intelligence, starting a merger between humans and machines that leads to immortality by 2045. De Grey argues that medical advances could make aging a curable disease by 2050, allowing people to live to 1,000 or beyond. Each of the next three breakthroughs offers a different path to immortality. They're not just about living longer - they're about changing what it means to be human. 2050: Immortality for the Elite By 2050, the wealthiest people could achieve immortality through a mix of cutting-edge technologies, predicts futurologist Dr Ian Pearson. He has suggested that advances in computing, genetic engineering, and robotics will let people live forever, either in enhanced bodies or as digital minds. 'By 2050, it will only really be for the rich and famous,' Pearson said, noting that these technologies will start expensive but become affordable by the 2060s for middle-class people. Pearson also envisioned a world where medical treatments fix deadly conditions, like heart disease or cancer, before they become fatal. Genetic engineering could reverse aging, keeping cells young and healthy. Meanwhile, technologies like brain-computer interfaces might let people 'upload' their minds into virtual reality or android bodies. 'This would allow people to have multiple existences and identities, or to carry on living long after their biological death,' Pearson explained. Although only the ultra-rich will be able to afford these breakthroughs at first, Pearson is optimistic that anyone under the age of 50 has got a good chance of affording this in their lifetime, and anyone under 40 will almost definitely will have access to immortality. His vision depends on technologies already in development, like 3D-printed organs and AI-driven medicine, scaling up dramatically in the next few decades. 2029: The Dawn of Human-Machine Hybrids By 2029, artificial intelligence will match human intelligence, kicking off a new era where humans merge with machines, according to Ray Kurzweil, a renowned futurist and former Google engineer. Kurzweil, who accurately predicted computers beating chess champions and the rise of smartphones, believes this milestone will lead to immortality by 2045, a point he calls 'The Singularity.' Kurzweil has predicted that AI will transform society, making necessities like food and housing cheaper and connecting human brains to the cloud via devices like Elon Musk's Neuralink. 'A key capability in the 2030s will be to connect the upper ranges of our neocortices to the cloud, which will directly extend our thinking,' he wrote in the 2024 book 'The Singularity Is Nearer.' According to Kurzweil, this merger will multiply human intelligence millions of times, letting us solve problems faster and live in new ways. By 2045, the futurist said humans could become cyborgs, capable of copying their minds or downloading into new bodies printed with advanced tech. 'Rather than AI being a competitor, it will become an extension of ourselves,' he explained. This vision starts in 2029, when AI reaches human levels of ability, setting the stage for a future where immortality means becoming part machine, part human. 2050: Curing Aging Like a Disease Aubrey de Grey, a Cambridge-educated scientist with a striking two-foot beard, believes aging is a disease we can cure. Through his Longevity Escape Velocity Foundation, de Grey has researched ways to repair the body's cells, potentially letting people live to 1,000. He's famously said the first person to reach 1,000 has already been born. De Grey's approach, called 'integrative rejuvenation,' uses multiple treatments to fix cellular damage, like clearing out harmful waste or repairing DNA. If medical advances keep pace with aging, humans could reach 'longevity escape velocity,' where life expectancy grows faster than time passes. 'Aging is a disease,' de Grey argued, saying that we should treat it like we treat cancer or diabetes. With a two-foot beard, Cambridge-educated author and 'immortalist' Aubrey de Grey believes that 'aging is a disease' and that will soon be possible to live until the age of 1,000 Other experts, like Dr Andrew Steele, author of 'Ageless,' have agreed that new drugs like senolytics could lead to healthier aging, even if not full immortality. Senolytics are a new class of drug designed to eliminate dead, 'zombie cells' from the body before they accumulate and contribute to harmful inflammation. 'We're at a point where we understand enough about the process that we can start to try to intervene,' Steele said. By 2050, de Grey's vision could make death from aging a thing of the past, offering a medical path to eternal life.
New York Post
a day ago
- Health
- New York Post
These 2 drugs made mice live 30% longer — why Bryan Johnson has warned of downsides
Biohackers, chew on this. Anti-aging aficionados have tried it all — including taking certain drugs off-label in the hopes they will lead to longer, healthier lives. A new study out of Germany provides fresh evidence that this approach may be worthwhile. Researchers at the Max Planck Institute for Biology of Aging found that a combination of two cancer drugs prolonged the lives of mice by about 30%. 4 Biohackers have tried it all — including taking certain drugs off-label in the hopes they will lead to longer, healthier lives. Prostock-studio – But buyer beware. One of the drugs, rapamycin, has sparked controversy over its safety and effectiveness in humans. Biohacking buff Bryan Johnson, 47, even admitted to dumping it from his regimen. Rapamycin is an immunosuppressant used to prevent organ rejection in transplant patients. The pill was found in the new study to increase mouse lifespan by 15% to 20% on its own. Rapamycin inhibits the mTOR pathway, which regulates major body functions such as protein synthesis, cell growth and the clearing of 'zombie' cells that don't function properly but refuse to die. Because it suppresses the immune system, one major downside of rapamycin is that it increases the risk of infections. Other potential side effects include elevated levels of cholesterol and triglycerides in the blood, gastrointestinal problems, skin issues, headaches, fatigue and drug interactions. 4 Prominent anti-aging enthusiast Bryan Johnson, 47, admitted to recently dumping rapamycin from his regimen. SXSW Conference & Festivals via Getty Images Johnson had experimented with different doses of the drug over five years before he stopped taking it in September. 'Despite the immense potential from pre-clinical trials, my team and I came to the conclusion that the benefits of lifelong dosing of rapamycin do not justify the hefty side effects (intermittent skin/soft tissue infections, lipid abnormalities, glucose elevations, and increased resting heart rate),' Johnson wrote in January. Rapamycin, along with trametinib, worked wonders in the new study. 4 The one-two punch of rapamycin and trametinib influenced gene expression differently than each drug by itself. K. Link / Max Planck Institute for Biology of Ageing Trametinib is used to treat certain types of melanoma and low-grade glioma, among other cancers. It interferes with the signals that tell cancer cells to multiply. Trametinib extended the mouse lives by 5% to 10% alone — and it was even better with rapamycin. 'Trametinib, especially in combination with rapamycin, is a good candidate to be tested in clinical trials as a geroprotector,' study author Sebastian Grönke said. 'We hope that our results will be taken up by others and tested in humans. Our focus is on optimizing the use of trametinib in animal models.' 4 Combination therapy was found to be more successful than the individual drugs. The Washington Post via Getty Images The one-two punch of rapamycin and trametinib influenced gene expression differently than each drug by itself. Researchers found lower amounts of harmful inflammation in the tissue and brain, and cancer didn't develop as fast. The findings were published this week in the journal Nature Aging. 'While we do not expect a similar extension to human lifespans as we found in mice, we hope that the drugs we're investigating could help people to stay healthy and disease-free for longer late in life,' co-senior author Linda Partridge said. 'Further research in humans in years to come will help us to elucidate how these drugs may be useful to people, and who might be able to benefit.'
Yahoo
2 days ago
- Business
- Yahoo
Billionaire Bryan Johnson says Bitcoin and human health have a ‘lot in common'
Billionaire Bryan Johnson says Bitcoin and human health have a 'lot in common' originally appeared on TheStreet. Biohacker and tech entrepreneur Bryan Johnson made a daring—and somewhat poetic—comparison between Bitcoin and human health. In a post on X that drew considerable attention, Johnson said, "Bitcoin, we have a lot in common…" and proceeded to break down how his personal longevity goals align with Bitcoin's principles. Using the commonly known phrases associated with crypto, Johnson wrote, "number go up, number go down," as he was alluding to Bitcoin's volatility and also his work to lower his resting heart rate before bed. He describes this trivial habit as making him happy, helping him sleep better, and even earning him more money, which means it is the "best thing for your health." He also pointed to the last Bitcoin halving, forecasted for 2140, and said that people should not miss it, implying the value of extending human life. He also said that Johnson, who is currently the front leader of the "Rejuvenation Olympics," biologically ages at a rate of 0.54—so when Johnson ages 6 months, that represents approximately 1.8 calendar years to the rest of the population. Comparing the limited supply of Bitcoin, Johnson stated, "There will only ever be 21 M. You only have one body; it's the most precious asset you own." His post also referenced another key principle of the crypto ecosystem: "don't trust, verify." In this case, Johnson emphasized the importance of objective health data, rather than trends, and advocated for a science-based perspective. By comparing biological longevity to digital scarcity, Johnson not only resonated with the crypto community but also re-framed the conversation around aging into a new, tech-based paradigm. Billionaire Bryan Johnson says Bitcoin and human health have a 'lot in common' first appeared on TheStreet on May 29, 2025 This story was originally reported by TheStreet on May 29, 2025, where it first appeared.
Time of India
2 days ago
- Health
- Time of India
Study reveals six foods that are proven to reverse ageing
Image credits: Getty Images Age reversing is currently the north star of the health industry. Every health or age-conscious person, influencer and brand is working towards the goal in one way or another that they make sure to promote if deemed beneficial. The concept of reverse ageing is related to your biological age, which is the age of the body on a physical and cellular level and not on the basis of the years you have been alive. These two ages- chronological and biological, can be different and the less your biological age is the more healthy your body is and the more lifespan you have. Thus, people are always configuring ways to reduce their biological age and stay healthy. The interest in the concept has led to the popularity of influencers such as Bryan Johnson and Mel Robbins who claim to have perfected the esteemed process. Now, a study published in the Aging journal by researchers from the University of Washington and other institutions has suggested that a diet rich in plant-based foods containing natural substances called methyl adaptogens can potentially slow biological ageing. What foods aid reverse ageing? Image credits: Getty Images The team wanted to investigate how dietary choices influenced DNA methylation, a process that regulates gene activity without affecting the DNA sequence itself. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like 5 Books Warren Buffett Wants You to Read In 2025 Blinkist: Warren Buffett's Reading List Undo The more the DNA methylation in specific sites in the genome, the higher a person's biological age is. In the study, the authors followed 43, healthy middle-aged men from Portland, Oregon who had finished an 8-week program that focused on a plant-based nutrient-rich diet along with exercise, sleep and stress reduction. The results showcased that those who consumed food with more polyphenols which have antioxidants and anti-inflammatory properties helped decrease the biological age by interfering with enzymes involved in DNA methylation. The authors recommended the daily consumption of dark leafy greens, cruciferous vegetables like broccoli, cauliflower, cabbage, colourful vegetables, pumpkin and sunflower seeds, beets, lean meats, low-glycemic fruits like apples, grapefruit and cherries and a serving or more from the methyl adaptogen group. They also suggested avoiding dairy, grains, legumes and alcohol. 6 foods that reverse age The study mentioned six foods that the participants consumed that had powerful impacts on declining their biological age. These include: Berries Image credits: Getty Images A half a cup of berries consumed daily can go a long way in reversing your biological age. According to a study published in the National Library of Medicine, berries contain polyphenolic compounds that lower oxidative stress and inflammation and alter the signalling involved in neuronal communication. This helps prevent age-related deficits in cognitive and motor function. Rosemary Image credits: Getty Images The effects of rosemary on hair health and growth have come to major limelight in recent times with doctors and influencers recommending using the herb in oils and waters to treat damaged hair. Now, researchers recommend consuming half a teaspoon of rosemary every day to aid in reversing biological ageing. In a study published in the National Library of Medicine, it was stated that rosemary extracts increased lifespan extension, and AMPK activation and improved cognitive function. Turmeric Image credits: Getty Images Turmeric is called the golden spice for a reason. The condiment has healing properties which have been known for years. But now, researchers recommend eating half a teaspoon of turmeric daily as the main active substance inside it, curcumin has anti-ageing properties as it changes the levels of proteins involved in the ageing process such as sirtuins and AMPK and inhibits pro-aging proteins such as NF-κB and mTOR, as mentioned in a National Library of Medicine study . Garlic Image credits: Getty Images Eating 2 cloves of garlic daily is said to be beneficial in reverse ageing. The antioxidant properties in the herb help it to prevent cerebral ageing, inhibit platelet aggregation, and improve blood circulation and energy levels, as cited in a study published in the National Library of Medicine. Green Tea Image credits: Getty Images Two cups of green tea daily is advised to be consumed by the study authors. It is able to delay collagen ageing with the help of its antioxidant mechanism. Additionally, it suppresses melanin production too which makes it a popular anti-ageing remedy, as mentioned in the National Library of Medicine. Oolong Tea Image credits: Getty Images If you are one of those rare people who do not like green tea, then study authors recommend swapping it with Oolong tea. You can also drink both. 3 cups of oolong tea daily is advisable to drink. Oolong tea is made from the leaves of the camellia sinensis plant and is partially oxidised. One step to a healthier you—join Times Health+ Yoga and feel the change
Time of India
3 days ago
- Business
- Time of India
2140 Bitcoin halving: Who is Bryan Johnson, the billionaire known for anti-ageing experiments and plans to live until 2140 to see Bitcoin's last halving?
Bryan Johnson Wants to Witness Bitcoin's Final Halving last bitcoin halving is in 2140i'm gonna be here for that and make sure you are too Bryan Johnson (@bryan_johnson) May 26, 2025 What Is Bitcoin Halving and Why Does Year 2140 Matter? What Do We Have in Common With Bitcoin? Bitcoin, we have a lot in common... number go upnumber go down- lower your resting heart rate before bed. It will boost your sleep, improve your mood and help you make more money. Best thing for your health. last bitcoin halving in 2140- we all want to be around for this,…— Bryan Johnson (@bryan_johnson) May 28, 2025 FAQs ADVERTISEMENT Billionaire biotech entrepreneur Bryan Johnson has revealed a bold plan to be alive for more than a century from now, as he intends to witness the final Bitcoin halving in the year 2140, as per a American entrepreneur and venture capitalist , recently wrote in a social media post on X (formerly Twitter) that, "Last Bitcoin halving is in 2140. I'm gonna be here for that — and make sure you are too," quoted The Street. His post was accompanied with a promotional poster for a conference where he is scheduled to speak from May 27 to May 29 in Las Vegas, as per the to The Street report, Bitcoin halving is a regular feature of the code in cryptocurrencies as almost every four years, the miner's reward for mining new Bitcoins is halved. This process reduces the total amount of Bitcoins mined over time, as per the is projected that the last bitcoin will be mined sometime in the year 2140, and at that time, the Bitcoin release will stop, and "the total number will reach a hard cap of 21 million", reported The who spends millions each year to change his biological age using experimental regenerative techniques , wrote another post on X, saying, "Bitcoin, we have a lot in go up, number go down" adding, "last bitcoin halving in 2140, we all want to be around for this, don't miss out," as per his X post on May 29. He highlighted in his post that, "1 BTC = 1 BTC, 1 YEAR = 0.5 MONTHS."He said he plans to be alive in 2140 to witness the last Bitcoin halving and wants others to be there the year when the final Bitcoin is expected to be mined, hitting its 21 million cap.
