Latest news with #Byetta
Medical News Today
03-06-2025
- Health
- Medical News Today
Byetta interactions: Supplements, alcohol, and more
Byetta has possible interactions with alcohol, some other drugs, and certain supplements. Examples include birth control pills and insulin medications. Talk with your doctor to avoid potentially harmful effects from Byetta interactions. An interaction occurs when one substance causes another substance to have a different effect than expected. By learning about possible Byetta interactions, you can work with your doctor to ensure that Byetta is safe and effective for you. » Learn more about Byetta, including details about its uses. Before you start treatment with Byetta, tell your doctor and pharmacist about any prescription, over-the-counter, and other medications you take. By sharing this information with them, you may help prevent possible interactions. To learn whether Byetta interacts with supplements, herbs, or vitamins, see the 'Byetta and other interactions' section. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Here's a table of drugs that can interact with Byetta. Keep in mind that this table doesn't include all drugs that may interact with Byetta. Some of these interactions are described in detail in 'Drug interactions in depth.' In some cases, factors or conditions could prevent your doctor from prescribing Byetta due to the risk of harm. These are known as contraindications. Here are the contraindications of Byetta. Note: Before you start treatment with Byetta, it's important to tell your doctor if these contraindications apply to you. They can determine whether to prescribe Byetta. Byetta and other drugs that contain exenatide can cause DITP. This side effect can be life threatening in rare cases. Due to this risk, doctors typically won't prescribe Byetta if you've had this reaction after using exenatide in the past. Instead, they'll likely prescribe a treatment other than Byetta for your condition. If you've had an allergic reaction to Byetta or any of its ingredients, your doctor will likely not prescribe Byetta. Using the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you. Drinking alcohol can cause your blood sugar level to drop. Consuming alcohol while using Byetta may raise your risk of low blood sugar levels. As a result, your doctor may suggest limiting alcohol consumption and avoiding excessive drinking while you're using Byetta. If you have questions about drinking alcohol during Byetta treatment, talk with your doctor. Here's a closer look at certain drug interactions of Byetta. Byetta interacts with birth control pills. In addition to preventing pregnancy, these medications have some other uses, such as treating premenstrual syndrome (PMS) episodes and managing acne. Byetta can affect how well your body absorbs any medication taken by mouth, including birth control pills. Injecting Byetta and taking a birth control pill at the same time may prevent your body from absorbing the birth control pill correctly. This can make the birth control pill less effective. Here are some birth control pills that may interact with Byetta: ethinyl estradiol/desogestrel (Cyclessa, others) ethinyl estradiol/drospirenone (Yaz, others) ethinyl estradiol/levonorgestrel (Ashlyna, others) ethinyl estradiol/norethindrone (Activella, others) ethinyl estradiol/norgestrel (Cryselle, others) Although Byetta and birth control pills interact, the effects of this interaction can be lowered by taking your pill at least one hour before injecting Byetta. Byetta can interact with insulin medications, which are prescribed for managing blood sugar levels in people with diabetes. Both Byetta and insulin work to lower blood sugar levels. Using them together can help keep blood sugar levels within your goal. However, they also raise the risk of low blood sugar as a side effect. Here are some insulin medications that may interact with Byetta: Although Byetta and insulins interact, they're still sometimes prescribed together. But your doctor may prescribe a lower insulin dosage if you also use Byetta. Talk with your doctor if you experience symptoms of low blood sugar, such as tremors, sweating, or dizziness. They may want to decrease your insulin dosage if you have this side effect during Byetta treatment Byetta interacts with sulfonylureas, which are medications used to manage high blood sugar caused by type 2 diabetes. Sulfonylureas and Byetta both work by lowering blood sugar levels. Using them together can be helpful when blood sugar remains high despite treatment with either drug on its own. But combining them also raises the risk of low blood sugar as a side effect. Here are some sulfonylurea medications that may interact with Byetta: glipizide (Glucotrol XL) glimepiride (Amaryl) glyburide (DiaBeta) Despite the interaction, Byetta and sulfonylureas are still sometimes prescribed together. In this case, your doctor will likely prescribe a lower dosage of the sulfonylurea if they recommend taking it with Byetta. Immediately let your doctor know if you're having symptoms of low blood sugar, such as dizziness, hunger, and irregular heartbeat. They may want to further lower your sulfonylurea dosage. Byetta may have other interactions, such as with supplements, foods, vaccines, or lab tests. Here are some potential interactions with Byetta. Keep in mind that the following information does not include all possible Byetta interactions. Before you start treatment with Byetta, tell your doctor and pharmacist about any supplements, herbs, and vitamins you take. By sharing this information with them, you may help prevent possible interactions. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Byetta interacts with garlic supplements, which may be used for several purposes, such as helping manage blood sugar. Both Byetta and garlic supplements can lower blood sugar levels. So using them together may raise your risk of low blood sugar. Byetta also interacts with green tea supplements, which are used for a range of potential health benefits, including lowering blood sugar and decreasing inflammation in the gut. Since green tea supplements may lower blood sugar levels, using Byetta and a green tea supplement at the same time may raise your risk of low blood sugar levels. For this reason, check with your doctor or pharmacist before using a garlic or green tea supplement if you're prescribed Byetta. They can advise whether this is safe for you. They may recommend that you closely monitor your blood sugar level at home if you use either supplement with Byetta. There are no specific reports of vitamins interacting with Byetta. However, that doesn't mean vitamin interactions won't occur or be recognized in the future. Because of this, you should talk with your doctor or pharmacist before taking any vitamin product with Byetta. Byetta may interact with green tea. Consuming green tea, especially in large amounts, may lower blood sugar. Since Byetta works to lower blood sugar, you may have a higher risk of low blood sugar levels if you consume a lot of green tea while using Byetta. Your doctor can adjust your Byetta dosage according to how much green tea you consume, but they'll likely ask you to keep your green tea consumption consistent. This can help your doctor determine the best Byetta dosage that keeps your blood sugar from staying too high or too low. Garlic supplements may interact with Byetta. But there's no expected interaction with garlic used in food. The amount of garlic in food is usually small. The food is also often divided into multiple servings. The amount of garlic would be much less than in a garlic supplement. If you have additional questions or want more information about eating certain foods during Byetta treatment, talk with your doctor. There aren't any known interactions between Byetta and vaccines. Talk with your doctor or pharmacist to check whether you're due for any vaccines. Byetta isn't known to interact with lab tests. If you have concerns about this medication interacting with lab tests, talk with your doctor. BYETTA INTERACTION WITH CANNABIS OR CBD Cannabis (often called marijuana) and cannabis products, such as cannabidiol (CBD), have not been specifically reported to interact with Byetta. However, as with any drug or supplement, talk with your doctor before using cannabis in combination with Byetta. The impact of cannabis may affect how well you stick to your Byetta treatment plan. Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees. Certain medical conditions and other factors may increase the risk of interactions with Byetta. Before you take this drug, be sure to talk with your doctor about your health history. Byetta may not be the right treatment option if you have certain medical conditions or other factors affecting your health. Health conditions or factors that might interact with Byetta include: Current or past pancreas condition: Byetta side effects include pancreatitis (inflammation in the pancreas). If you have or have had a pancreas condition such as pancreatitis, you may have an increased risk of this side effect. Talk with your doctor to learn more about whether Byetta treatment is safe for you. Byetta side effects include pancreatitis (inflammation in the pancreas). If you have or have had a pancreas condition such as pancreatitis, you may have an increased risk of this side effect. Talk with your doctor to learn more about whether Byetta treatment is safe for you. Digestive system problems, especially delayed stomach emptying: Using Byetta is not recommended if you have a severe digestive condition, especially gastroparesis or another condition that slows stomach emptying. Instead, your doctor can review other treatments for type 2 diabetes that are safer for you to use. Using Byetta is not recommended if you have a severe digestive condition, especially gastroparesis or another condition that slows stomach emptying. Instead, your doctor can review other treatments for type 2 diabetes that are safer for you to use. Kidney condition, including past kidney transplant: Byetta side effects can include worsened kidney function and sudden kidney failure. Before you start using Byetta, let your doctor know if you have chronic kidney disease or another kidney condition. Depending on the severity of your kidney condition, Byetta may not be safe for you to use. Or your doctor may prescribe a lower Byetta dosage depending on your kidney function. Byetta side effects can include worsened kidney function and sudden kidney failure. Before you start using Byetta, let your doctor know if you have chronic kidney disease or another kidney condition. Depending on the severity of your kidney condition, Byetta may not be safe for you to use. Or your doctor may prescribe a lower Byetta dosage depending on your kidney function. Scheduled surgery: Treatment with Byetta can raise the risk of food getting into your lungs during procedures that require anesthesia or sedation, such as surgery. Talk with your doctor before undergoing such procedures during Byetta treatment. They may recommend temporarily pausing Byetta treatment for some time before the procedure, and they can advise when it's safe for you to continue treatment afterward. Treatment with Byetta can raise the risk of food getting into your lungs during procedures that require anesthesia or sedation, such as surgery. Talk with your doctor before undergoing such procedures during Byetta treatment. They may recommend temporarily pausing Byetta treatment for some time before the procedure, and they can advise when it's safe for you to continue treatment afterward. Allergic reaction: If you've had an allergic reaction to Byetta or any of its ingredients, your doctor will likely not prescribe Byetta. Using the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you. If you've had an allergic reaction to Byetta or any of its ingredients, your doctor will likely not prescribe Byetta. Using the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you. Breastfeeding: It's not known whether it's safe to use Byetta while breastfeeding. There isn't enough information to determine whether the drug passes into breast milk or what effects Byetta may have on a child who is breastfed. If you're breastfeeding or planning to, talk with your doctor before using Byetta. They can discuss treatment options and ways to feed a child other than breastfeeding. It's not known whether it's safe to use Byetta while breastfeeding. There isn't enough information to determine whether the drug passes into breast milk or what effects Byetta may have on a child who is breastfed. If you're breastfeeding or planning to, talk with your doctor before using Byetta. They can discuss treatment options and ways to feed a child other than breastfeeding. Pregnancy: There haven't been enough clinical trials to determine whether Byetta is safe to use while pregnant. Animal studies show that the drug may cause congenital anomalies (commonly known as birth defects) or pregnancy loss. However, it's important to note that animal studies don't always indicate what may happen in humans. And high blood sugar levels are known to increase certain risks during pregnancy. If you're pregnant or planning to become pregnant, tell your doctor before starting Byetta. They can advise the right treatment plan for you. You can take certain steps to help prevent interactions with Byetta. Your doctor and pharmacist are key resources, so reaching out to them before starting treatment is a helpful first step. For example, it's important that you plan to do the following: Let them know if you drink alcohol or use cannabis. Tell them about any other medications you take, as well as any supplements, herbs, and vitamins. Create a medication list , which your doctor and pharmacist can help you fill out. It's also important to read the Byetta label and other paperwork that may come with the drug. The label may have colored stickers that mention an interaction. The paperwork, sometimes called the medication guide or patient package insert, may contain details about interactions. If Byetta doesn't come with paperwork, you can ask your pharmacist to print a copy. If you need help reading or understanding this information, ask your doctor or pharmacist. You can also help prevent interactions with Byetta by using it exactly as your doctor prescribes. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Diabetes Type 2 Pharmacy / Pharmacist Drugs
Yahoo
13-05-2025
- Health
- Yahoo
GLP-1RAs show anti-cancer benefits beyond weight loss
A study has found that glucagon-like peptide-1 receptor agonists (GLP-1RAs) offer anti-cancer benefits that extend beyond their role in promoting weight loss. The observational study (COM2-0186-22), presented during the European Congress on Obesity (ECO) taking place in Malaga, Spain between 11-14 May and published in the journal eClinicalMedicine, investigated first-generation GLP-1RAs Victoza (liraglutide) and Byetta (exenatide). The study found that GLP1-RAs had a direct effect on reducing obesity-related cancer beyond weight loss, with a 41% lower relative risk compared to bariatric surgery. Researchers analysed electronic health record data and over a median follow-up of 7.5 years, 298 patients were diagnosed with obesity-related cancer. Of these cases, 150 were from 3,178 surgery patients (5.76 cases per 1,000 person-years) compared with 148 cases from 3,178 patients taking GLP-1RAs (5.64 cases per 1,000 person-years). This comes as bariatric surgery in weight reduction is already known to reduce cancer risk. The most common cancer was postmenopausal breast cancer (26%), followed by colorectal cancer (16%), and cancer of the uterus (15%). To assess the comparative effect beyond the extent of weight loss (which mediates the reduction in cancer risk following treatment), the researchers further adjusted the analysis for the percentage of maximal BMI change during follow-up. Co-lead author Dr Yael Wolff Sagy from Clalit Health Services, Tel-Aviv, Israel, said: 'Our study found a similar incidence of obesity-related cancer among patients treated with first-generation GLP-1RAs and with bariatric surgery over an average of 8 years follow-up, despite the relative advantage of surgery in maximising weight loss. But accounting for this advantage revealed the direct effect of GLP-1RAs beyond weight loss to be 41% more effective at preventing obesity-related cancer.' Of the 6,356 study participants, 3,884 (61.1%) were females. At baseline, the mean age was 52.3 years, and the mean BMI was 41.5kg/m². Both obesity and diabetes are linked with an increased risk for many types of cancer, referred to as obesity-related cancer, including colorectal cancer, corpus uteri cancer, meningioma and ovarian cancer, as well as multiple myeloma. Investigators are now calling for randomised trials and larger prospective studies to confirm the anti-cancer effects of GLP-1RAs noted in the observational study and explore the underlying mechanisms. GLP-1RAs are also being investigated in other indications beyond obesity and type 2 diabetes, including Alzheimer's disease, addictive disorders and psychiatric disorders. GLP-1RAs have grown massively in recent years following the release of Novo Nordisk's semaglutide, marketed as Ozempic in type 2 diabetes and Wegovy in obesity, and Eli Lilly's tirzepatide, marketed as Mounjaro in type 2 diabetes and Zepbound in obesity. GlobalData analysis predicts the global GLP-1RA market will reach $168bn by 2033. Research also predicts Novo Nordisk and Eli Lilly will dominate the market, collectively capturing 94% of the total 2030 GLP-1RA sales. GlobalData is the parent company of Clinical Trials Arena. "GLP-1RAs show anti-cancer benefits beyond weight loss" was originally created and published by Clinical Trials Arena, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site.
Yahoo
13-05-2025
- Health
- Yahoo
GLP-1RAs show anti-cancer benefits beyond weight loss
A study has found that glucagon-like peptide-1 receptor agonists (GLP-1RAs) offer anti-cancer benefits that extend beyond their role in promoting weight loss. The observational study (COM2-0186-22), presented during the European Congress on Obesity (ECO) taking place in Malaga, Spain between 11-14 May and published in the journal eClinicalMedicine, investigated first-generation GLP-1RAs Victoza (liraglutide) and Byetta (exenatide). The study found that GLP1-RAs had a direct effect on reducing obesity-related cancer beyond weight loss, with a 41% lower relative risk compared to bariatric surgery. Researchers analysed electronic health record data and over a median follow-up of 7.5 years, 298 patients were diagnosed with obesity-related cancer. Of these cases, 150 were from 3,178 surgery patients (5.76 cases per 1,000 person-years) compared with 148 cases from 3,178 patients taking GLP-1RAs (5.64 cases per 1,000 person-years). This comes as bariatric surgery in weight reduction is already known to reduce cancer risk. The most common cancer was postmenopausal breast cancer (26%), followed by colorectal cancer (16%), and cancer of the uterus (15%). To assess the comparative effect beyond the extent of weight loss (which mediates the reduction in cancer risk following treatment), the researchers further adjusted the analysis for the percentage of maximal BMI change during follow-up. Co-lead author Dr Yael Wolff Sagy from Clalit Health Services, Tel-Aviv, Israel, said: 'Our study found a similar incidence of obesity-related cancer among patients treated with first-generation GLP-1RAs and with bariatric surgery over an average of 8 years follow-up, despite the relative advantage of surgery in maximising weight loss. But accounting for this advantage revealed the direct effect of GLP-1RAs beyond weight loss to be 41% more effective at preventing obesity-related cancer.' Of the 6,356 study participants, 3,884 (61.1%) were females. At baseline, the mean age was 52.3 years, and the mean BMI was 41.5kg/m². Both obesity and diabetes are linked with an increased risk for many types of cancer, referred to as obesity-related cancer, including colorectal cancer, corpus uteri cancer, meningioma and ovarian cancer, as well as multiple myeloma. Investigators are now calling for randomised trials and larger prospective studies to confirm the anti-cancer effects of GLP-1RAs noted in the observational study and explore the underlying mechanisms. GLP-1RAs are also being investigated in other indications beyond obesity and type 2 diabetes, including Alzheimer's disease, addictive disorders and psychiatric disorders. GLP-1RAs have grown massively in recent years following the release of Novo Nordisk's semaglutide, marketed as Ozempic in type 2 diabetes and Wegovy in obesity, and Eli Lilly's tirzepatide, marketed as Mounjaro in type 2 diabetes and Zepbound in obesity. GlobalData analysis predicts the global GLP-1RA market will reach $168bn by 2033. Research also predicts Novo Nordisk and Eli Lilly will dominate the market, collectively capturing 94% of the total 2030 GLP-1RA sales. GlobalData is the parent company of Clinical Trials Arena. "GLP-1RAs show anti-cancer benefits beyond weight loss" was originally created and published by Pharmaceutical Technology, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Sign in to access your portfolio
