Latest news with #Clade
The Age
22-04-2025
- Entertainment
- The Age
James Bradley's new novel subverts the classic crime-solving trope
Landfall James Bradley Penguin, $34.99 The progress of Tropical Cyclone Alfred towards landfall across south-east Queensland and northern New South Wales prompted warnings and evacuations in areas not typically in the direct path of such severe weather. As communities in Brisbane, the Gold Coast and Northern Rivers braced for impact, I switched between scrolling news reports and social media updates on Alfred, and reading James Bradley's remarkably prescient novel, Landfall. The third instalment in his critically acclaimed climate fiction series, Landfall builds on the themes of its predecessors, Clade and Ghost Species, along with Bradley's 'climate project' —long and short fiction for adults and young people, essays, journalism and non-fiction books — all centred on exploring the impacts and possible remedies to the human-induced climate crisis. While no stranger to writing eco-thrillers, this time Bradley flips the well-loved Australian trope of the missing child by transporting it from its cliched bush setting into a post-climate-apocalypse Sydney, producing a genre mash-up of cli-fi and detective fiction. 'The Melt' — a tipping point climate event — has seen the great Antarctic ice sheets crash into the ocean, sending water levels rising across the world. The Sydney of Landfall is a world inhabited by characters whose lives are irreparably transformed by climate catastrophe, a city whose flooded streets, scorchingly hot suburbs, and social divides, are both alien and unsettlingly familiar. When five-year-old Casey Mitchell goes missing, suspected abducted, Senior Detective Sadiya Azad and her partner Detective Sargeant Paul Findlay, are dispatched to the city's margins to investigate the case. The 'Floodline', a series of half-submerged houses and apartments strung together with makeshift duckboards and pontoons, is home to Casey's mother, Emma and stepfather, Jay, who immediately becomes a suspect based on his social media links to white supremacist groups. Bradley furnishes the novel with the requisite cast of shady characters to question and eliminate: a convicted paedophile lurking around the scene of the girl's disappearance, the head honcho of an exploitative corporation having an illicit love affair, an ex-junkie relative of a person of interest, and various other crooks and rogues operating in a web of corruption who round out the whodunit. When the body of a seemingly unrelated woman turns up in the boot of a burnt-out car, the case becomes curiouser and curiouser. In Landfall, environmental devastation is not merely a backdrop to the action; it is a central character and driving narrative. The police investigation into Casey's disappearance is hindered by the everyday reality of living with the extreme heat and inundation of a coastal city on the brink of societal collapse. The novel's chapters are titled by days of the week, running Monday through Friday. Each passing day builds the urgency of finding the girl and is amplified by the impending landfall of Nasreem, 'a massive cyclone …building over the Pacific', which is expected to be unprecedented in scale and devastation. Bradley's world-building in this speculative novel is never heavy-handed. Future tech feels near-at-hand: drones collecting footage of protesters, AI assistants and AR lenses, a failing power grid, and street cooling, while the tumultuous world of crop failures, fires, floods and hurricanes is an all too foreseeable future, 'created decades before catching up with the world'.
Sydney Morning Herald
22-04-2025
- Entertainment
- Sydney Morning Herald
James Bradley's new novel subverts the classic crime-solving trope
Landfall James Bradley Penguin, $34.99 The progress of Tropical Cyclone Alfred towards landfall across south-east Queensland and northern New South Wales prompted warnings and evacuations in areas not typically in the direct path of such severe weather. As communities in Brisbane, the Gold Coast and Northern Rivers braced for impact, I switched between scrolling news reports and social media updates on Alfred, and reading James Bradley's remarkably prescient novel, Landfall. The third instalment in his critically acclaimed climate fiction series, Landfall builds on the themes of its predecessors, Clade and Ghost Species, along with Bradley's 'climate project' —long and short fiction for adults and young people, essays, journalism and non-fiction books — all centred on exploring the impacts and possible remedies to the human-induced climate crisis. While no stranger to writing eco-thrillers, this time Bradley flips the well-loved Australian trope of the missing child by transporting it from its cliched bush setting into a post-climate-apocalypse Sydney, producing a genre mash-up of cli-fi and detective fiction. 'The Melt' — a tipping point climate event — has seen the great Antarctic ice sheets crash into the ocean, sending water levels rising across the world. The Sydney of Landfall is a world inhabited by characters whose lives are irreparably transformed by climate catastrophe, a city whose flooded streets, scorchingly hot suburbs, and social divides, are both alien and unsettlingly familiar. When five-year-old Casey Mitchell goes missing, suspected abducted, Senior Detective Sadiya Azad and her partner Detective Sargeant Paul Findlay, are dispatched to the city's margins to investigate the case. The 'Floodline', a series of half-submerged houses and apartments strung together with makeshift duckboards and pontoons, is home to Casey's mother, Emma and stepfather, Jay, who immediately becomes a suspect based on his social media links to white supremacist groups. Bradley furnishes the novel with the requisite cast of shady characters to question and eliminate: a convicted paedophile lurking around the scene of the girl's disappearance, the head honcho of an exploitative corporation having an illicit love affair, an ex-junkie relative of a person of interest, and various other crooks and rogues operating in a web of corruption who round out the whodunit. When the body of a seemingly unrelated woman turns up in the boot of a burnt-out car, the case becomes curiouser and curiouser. In Landfall, environmental devastation is not merely a backdrop to the action; it is a central character and driving narrative. The police investigation into Casey's disappearance is hindered by the everyday reality of living with the extreme heat and inundation of a coastal city on the brink of societal collapse. The novel's chapters are titled by days of the week, running Monday through Friday. Each passing day builds the urgency of finding the girl and is amplified by the impending landfall of Nasreem, 'a massive cyclone …building over the Pacific', which is expected to be unprecedented in scale and devastation. Bradley's world-building in this speculative novel is never heavy-handed. Future tech feels near-at-hand: drones collecting footage of protesters, AI assistants and AR lenses, a failing power grid, and street cooling, while the tumultuous world of crop failures, fires, floods and hurricanes is an all too foreseeable future, 'created decades before catching up with the world'.
Associated Press
04-03-2025
- Health
- Associated Press
Registration is Now Open For Tribe Public's CEO Presentation and Q&A Webinar Event MPOX 2025: Navigating the Global Public Health Emergency Featuring GeoVax CEO On March 6, 2025
Mpox remains a global public health crisis in 2025, with Clade 1b exhibiting higher transmissibility and severity than Clade 2. The Democratic Republic of the Congo (DRC) is the epicenter, with over 60,000 suspected cases and 1,300 deaths in 2024 alone. The virus has now spread to multiple countries, including the U.S., Canada, and Europe, raising concerns about global containment. The U.S. has confirmed four Clade 1b cases (California, Georgia, New Hampshire, and New York), prompting the need for urgent action. The current vaccine supply chain is inadequate, relying heavily on a single non-U.S. manufacturer. Delays in vaccine distribution, high costs, and limited production capacity have exacerbated the crisis, particularly in Africa, where vaccine stockpiles remain largely unused due to logistical and political challenges. GEO-MVA, the GeoVax Mpox vaccine candidate is advancing to clinical evaluation, anticipated for H2 '25. ATLANTA, GA - March 4, 2025 ( NEWMEDIAWIRE) - GeoVax Labs, Inc. (Nasdaq: GOVX), a clinical-stage biotechnology company developing immunotherapies and vaccines against cancers and infectious diseases, announces that Chairman & CEO, David Dodd will present at Tribe Public's CEO Presentation and Q&A Webinar Event titled 'MPOX 2025: Navigating the Global Public Health Emergency.' The Event is scheduled to begin at 8:30am Pacific/11:30am Eastern on Thursday, March 6, 2025. To register to join the complimentary, ZOOM webinar-based event, please visit Once registered, participants may begin forwarding their questions for GeoVax's management to Tribe Public at [email protected] or share their questions via the ZOOM chat feature during the event. Tribe Public's Managing Member, John F. Heerdink, Jr., will host the event and relay all questions to management. About GeoVax GeoVax Labs, Inc. is a clinical-stage biotechnology company developing novel vaccines for many of the world's most threatening infectious diseases and therapies for solid tumor cancers. The company's lead clinical program is GEO-CM04S1, a next-generation COVID-19 vaccine for which GeoVax was recently awarded a BARDA-funded contract to sponsor a 10,000-participant Phase 2b clinical trial to evaluate the efficacy of GEO-CM04S1 versus an approved COVID-19 vaccine. In addition, GEO-CM04S1 is currently in three Phase 2 clinical trials, being evaluated as (1) a primary vaccine for immunocompromised patients such as those suffering from hematologic cancers and other patient populations for whom the current authorized COVID-19 vaccines are insufficient, (2) a booster vaccine in patients with chronic lymphocytic leukemia (CLL) and (3) a more robust, durable COVID-19 booster among healthy patients who previously received the mRNA vaccines. In oncology the lead clinical program is evaluating a novel oncolytic solid tumor gene-directed therapy, Gedeptin(R), having recently completed a multicenter Phase 1/2 clinical trial for advanced head and neck cancers. A Phase 2 clinical trial in first recurrent head and neck cancer, evaluating Gedeptin(R) combined with an immune checkpoint inhibitor is planned. GeoVax has a strong IP portfolio in support of its technologies and product candidates, holding worldwide rights for its technologies and products. The Company has a leadership team who have driven significant value creation across multiple life science companies over the past several decades. For more information about the current status of our clinical trials and other updates, visit our website : About Tribe Public LLC Tribe Public LLC is a San Francisco, CA based organization that hosts complimentary worldwide webinar & in-person meeting events across 36 venue sites in the U.S. Tribe's events focus on issues that the Tribe members care about with an emphasis on hosting management teams from companies from all sectors & financial organizations that are seeking to increase awareness of their products, progress and plans. Tribe members primarily include Family Offices, Portfolio Managers, Registered Investment Advisors, Accredited Investors, Sell Side Analysts, and members of media. Tribe Members are encouraged to express their interest in speakers they care about and want to learn from at the Tribe Public website via the Tribe's FREE 'Wish List' process. Visit Tribe Public's Website to learn more: 678-384-7220 212-698-8696 Media Contact: 202-779-0929
