Latest news with #DO-HEALTH


Jordan News
3 days ago
- Health
- Jordan News
Simple Habits That Trick Your Body into Staying Young - Jordan News
Simple Habits That Trick Your Body into Staying Young A recent study has found that combining three simple lifestyle factors can significantly slow down the biological aging process in people over the age of 70. اضافة اعلان The promising findings come from the renowned DO-HEALTH study, led by a research team at the University of Zurich under Professor Heike Bischoff-Ferrari. The three-year study involved 777 participants and relied on cutting-edge technology known as epigenetic clocks—developed by scientist Steve Horvath—which track subtle chemical changes in DNA to accurately measure a person's biological age, rather than their chronological age. The Powerful Trio: Omega-3, Vitamin D, and Strength Training The study revealed that the combination of omega-3 supplements, vitamin D, and regular strength exercises significantly slowed down biological aging in people in their seventies. Taking omega-3 supplements alone was shown to reduce biological age by up to four months, regardless of gender or body mass index. However, the most striking results appeared when participants combined all three elements: omega-3, vitamin D, and at-home strength training three times a week. This synergy created a compounding effect that slowed aging much more effectively than any of the components alone. Professor Bischoff-Ferrari explains: "These three elements act through different but complementary mechanisms—omega-3 supports cellular health, vitamin D boosts vital functions, and strength training promotes tissue regeneration. Together, they deliver a much more powerful anti-aging impact." The study adds to earlier findings that this combination also reduces the risk of cancer, frailty, and infections in older adults. However, this is the first time such a direct impact on the aging process itself has been demonstrated. Promising but Early Despite the encouraging results, researchers caution that the study is still in its early stages. It was conducted only on participants in Switzerland, and epigenetic clock technologies are still evolving. Nevertheless, the research team is now planning to expand the study across other European countries, in collaboration with an international alliance focused on extending healthy lifespan. In the end, it seems the key to slowing down time may not lie in a complicated drug or high-tech procedure—but in daily habits that anyone can adopt. Professor Bischoff-Ferrari concludes: "Aging is a complex process, but this study shows that we already have some simple tools to positively influence it." Source: SciTechDaily
Yahoo
13-05-2025
- Health
- Yahoo
The Academy for Health and Lifespan Research Announces the Addition of Leading Scientists Driving Breakthroughs in Aging Research
NEW YORK, May 13, 2025 /PRNewswire/ -- The Academy for Health and Lifespan Research (AHLR, "the Academy"), has announced the induction of 24 distinguished scientists whose groundbreaking contributions are shaping the future of aging and healthspan research. The new members bring a wealth of expertise and groundbreaking research that will significantly enhance the Academy's collective mission to advance the field of aging research. Representing leading universities and institutions worldwide, these researchers have advanced the understanding of the biology of aging, the prevention of age-related diseases, and interventions to extend healthy human lifespan. Their work spans molecular biology, clinical geroscience, genetics, metabolism, and translational science, collectively driving progress toward a healthier future for all generations. The Academy welcomes: Arne Akbar — University College London Professor Akbar is a leading immunologist whose work focuses on how immune function changes with age, particularly in T cell biology and inflammation. Uri Alon — Weizmann Institute of Science Professor Alon is a renowned systems biologist who has redefined approaches to cellular aging through his studies of gene networks and biological robustness. Andrzej Bartke — Southern Illinois School of Medicine Dr. Bartke is a researcher studying the relationship of growth hormone and pace-of-life to aging, as well as the potential of early life interventions to promote healthy aging. Heike A. Bischoff-Ferrari — University of Basel Professor Bischoff-Ferrari is the principal investigator of the 5-country European Healthy Longevity trial and biobank DO-HEALTH. Her research on vitamin D, omega-3 and exercise, connecting clinical outcomes of healthy longevity to biological aging, led to critical advances in preventive medicine for older adults. Anne Brunet — Stanford University Professor Brunet investigates the molecular mechanisms of aging and longevity, particularly using model organisms to understand the regulation of lifespan. Rochelle Buffenstein — University of Illinois-Chicago Dr. Buffenstein, is renowned for her pioneering research on the naked mole-rat's exceptional longevity and resistance to age-related diseases. Her expertise lies in comparative biology, focusing on aging, proteostasis, and the molecular mechanisms that enable certain mammals to maintain healthspan and resist age-associated decline. Haim Cohen — Bar-Ilan UniversityProfessor Cohen is an expert on metabolic regulation and aging, notably advancing our understanding of sirtuin biology and healthy lifespan extension. Sara Espinoza — Cedars Sinai Medical CenterDr. Espinoza leads translational research focused on frailty, developing strategies to enhance resilience and functional independence in older adults. Toren Finkel — University of PittsburghDr. Finkel's work on oxidative stress, mitochondrial biology, and age-related disease has made major contributions to strategies for extending healthspan. David Glass — Regeneron PharmaceuticalsDr. Glass is a leader in biotech innovation, advancing therapies to combat muscle loss and metabolic decline associated with aging. Derek Huffman — Albert Einstein College of MedicineDr. Huffman's research bridges metabolism, energy regulation, and aging biology, identifying new strategies for combating age-related diseases. Stephen Kritchevsky — Wake Forest School of MedicineProfessor Kritchevsky is a foremost expert in geriatric epidemiology, specializing in the prevention of frailty and disability in older adults. Nathan LeBrasseur — Mayo ClinicDr. LeBrasseur is a translational scientist dedicated to improving mobility and combating muscle loss in aging populations. Dudley Lamming — University of Wisconsin–MadisonDr. Lamming investigates how nutrient signaling pathways like mTOR respond to dietary composition and small molecules, with the goal of developing therapies that slow aging and improve long-term health. Morgan Levine — Altos LabsDr. Levine is a leading biogerontologist known for developing computational models to quantify biological aging across cells, tissues, and organisms. Valter Longo — University of Southern CaliforniaProfessor Longo is an internationally recognized leader in nutrition and fasting research, developing interventions to delay aging and prevent disease. William Mair — Harvard T.H. Chan School of Public HealthDr. Mair explores the effects of dietary and metabolic regulation on cellular mechanisms of aging and longevity. Benjamin Miller — Oklahoma Medical Research Miller is a translational researcher who studies mitochondria and protein homeostasis to implement lifestyle and drug interventions to slow aging. Daniel Promislow — University of Washington Professor Promislow is a leader in the genetics of aging, using comparative biology to uncover the causes of lifespan variation within and across species. Jing Qu — Chinese Academy of SciencesDr. Qu's research focuses on understanding molecular and cellular pathways that drive aging and age-associated diseases. Morten Scheibye-Knudsen — University of CopenhagenDr. Scheibye-Knudsen investigates the molecular basis of human aging and how we can develop interventions leading to healthy aging. John Speakman — University of Aberdeen and Chinese Academy of Sciences Professor Speakman is a globally recognized expert on energy metabolism, obesity, calorie restriction and the biology of aging in diverse species. Dario Valenzano — Leibniz Institute of AgeingDr. Valenzano uses evolutionary genomics and naturally short-lived fish models to decode the genetic architecture of aging. Ned Sharpless — Jupiter BioventuresDr. Sharpless, former Director of the National Cancer Institute, investigates the links between cellular senescence, cancer, and aging. He is the co-founder and Managing Director of Jupiter Bioventures. "We're honored to welcome these outstanding scientists to the Academy," said Nir Barzilai, MD, President of the Academy for Health and Lifespan Research. "As a global organization, we reflect the growing momentum in aging science—from cells to cities to countries. With each new member, we strengthen our shared mission and collective wisdom to extend healthspan and improve quality of life through rigorous, transformative research." About AHLR:The Academy for Health and Lifespan Research (AHLR) is a non-profit organization founded in 2019, dedicated to advancing aging research, supporting scientists, advising on public policy, and fostering collaboration. By uniting the world's leading scientists, laboratories, academic institutions, and drug companies, AHLR strives to encourage breakthroughs in longevity research that are accessible to all. Follow us on X: ahlresearch View original content to download multimedia: SOURCE Academy for Health & Lifespan Research
Yahoo
07-04-2025
- Health
- Yahoo
Common supplement could help you live longer, research suggests
New research has identified a common supplement that could boost longevity. Omega-3, a "healthy fat" that can help improve brain and heart health, has been found to also slow down biological aging. Researchers in Switzerland studied 777 participants ranging from 70 to 85 years old in a randomized clinical trial called DO-HEALTH over a three-year period. Healthy Eating In Middle Age Has This Key Longevity Benefit The participants took daily omega-3 (1-gram) supplements, as well as a daily vitamin D supplement (2,000 IU), and/or participated in an at-home exercise program. Upon measuring biological aging in the individuals at the end of the trial, researchers found that omega-3 alone slowed biological aging markers. Read On The Fox News App The study, published in the journal Nature, found a three- to four-month rejuvenation in biological aging, a 61% cancer risk reduction and 39% reduction in pre-frailty risk (a risk state that precedes frailty or weakness). Diabetes Risk Lowered By Eating One Surprisingly Sweet Food, Study Suggests This effect was stronger when omega-3 supplementation was combined with daily vitamin D and at least 30 minutes of simple strength training three times per week, according to researchers. Study co-author Professor Heike Bischoff-Ferrari of the University of Basel in Switzerland shared the impact of the clinical trial. "DO-HEALTH is the largest clinical trial to date showing that we can rejuvenate biological aging in humans aged 70 and older, and this with simple strategies," he told Fox News Digital. "As in the same trial, the interventions also reduced cancer risk and early frailty. This is relevant to public health efforts." Click Here To Sign Up For Our Health Newsletter The professor noted that the study findings support the supplementation of 1 gram of algae-based omega-3 daily "as safe and effective." Fox News senior medical analyst Dr. Marc Siegel applauded the findings, noting that the impact over just three years is "significant, with an additive impact of vitamin D." The doctor said he believes omega-3 fatty acids can impact longevity due to their antioxidant properties. For more Health articles, visit "[Antioxidants] work as an anti-inflammatory in the body and are good for heart health," he told Fox News Digital. "Inflammation is behind many chronic diseases that may shorten health span and lifespan, from heart disease to high cholesterol to cancer." Fatty types of fish, including salmon, tuna and mackerel, are also rich sources of omega-3 fatty acids. Those interested in taking omega-3 supplements should see their doctor to discuss potential benefits and risks, experts article source: Common supplement could help you live longer, research suggests
Yahoo
29-03-2025
- Health
- Yahoo
Researchers Say Taking This Supplement Every Day Can Slow Down Aging
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." Researchers just discovered yet another reason you might want to take an omega-3 supplement. When they analyzed data from 777 participants age 70 and older in the DO-HEALTH trial, they found that taking 1 gram of omega-3 fatty acids every day was linked to slower biological aging. Yes, many different factors affect how fast you age, but taking a supplement could be one easy way to help keep your cells younger for longer. Omega-3 fatty acids are involved in the structure of our cell membranes, provide energy for our body and help form signaling molecules for our cardiovascular, pulmonary, immune and endocrine systems, according to the National Institutes of Health. On top of many other health benefits, this new research suggests omega-3 fatty acids may also be a key ingredient in the aging process. 'One of the most critical questions in the field of rejuvenation is whether a treatment exists that can effectively rejuvenate humans not just mice,' says Heike Bischoff-Ferrari, Dr.P.H., M.P.H., a clinical scientist and medical doctor with a focus on healthy longevity at the University of Basel, Switzerland, and co-author of the new study. 'This motivated us to explore whether three simple interventions — omega-3, vitamin D and exercise — influence the most reliable molecular markers of biological age: epigenetic clocks.' Here's everything you need to know. Epigenetic clocks are tools that look for chemical changes that occur in genetic material to identify patterns and, as a result, measure biological age. 'We age in a spectrum,' says Bischoff-Ferrari. 'Some people are biologically younger than their chronological age (age in our passport) and others are biologically older.' A variety of epigenetic clocks have been invented to measure biological age in different ways, so there isn't a single test that can tell you definitively what your biological age is. The researchers who conducted this study used four epigenetic clocks to get a range of measurements. 'The good news is that we know today that only a small part (10 to 30%) of the variability of health span is explained by our genes,' says Bischoff-Ferrari. 'The rest is determined by our environment, socioeconomic factors and especially lifestyle, such as exercise and diet.' Bischoff-Ferrari and her colleagues used epigenetic clocks to measure the biological ages of people who took 1 gram of an algae-based omega-3 supplement daily, 2,000 IU of vitamin D daily and/or participated in a strength-training exercise program for 30 minutes three times per week. People who took the omega-3 supplement every day for three years had a biological age that was an average of 3 months younger than their chronological age, according to three of the four epigenetic clocks. The fourth clock showed 'there was an additional benefit if omega-3 was combined with vitamin D and exercise,' says Bischoff-Ferrari. Three months may not sound like much, but Bischoff-Ferrari says it's enough to have an impact at the population level. No one knows exactly why omega-3 fatty acids could have such a strong effect on the aging process, but there are plenty of hypotheses. 'Notably, these results complement previous clinical findings in the same trial (DO-HEALTH), which found that omega-3 lowered the rate of falls by 10% and reduced the rate of infections by up to 13%, while omega-3, vitamin D and exercise combined lowered the risk of pre-frailty by 39% and invasive cancer by 61%,' says Bischoff-Ferrari. It seems as though omega-3 fatty acids, vitamin D and exercise could provide a triple-whammy of aging protection. 'It is well-documented in basic science that vitamin D prevents uncontrolled cell growth and has anti-inflammatory benefits,' says Bischoff-Ferrari. Meanwhile, exercise is famous for being 'a major driver of healthy longevity with protective effects on most age-related chronic diseases, such as heart disease, cancer, osteoporosis and diabetes,' she says. This study shows how powerful small lifestyle changes (such as taking a supplement or starting a new exercise regimen) can be when it comes to protecting our health and slowing down the aging process of our cells. As important as they are for our health and longevity, omega-3 fatty acids aren't easily created in our bodies, so we need to source them from food and supplements. Foods rich in omega-3s include fatty fish (such as salmon), nuts (like walnuts), seeds (chia seeds, for instance), plant oils (like soybean oil and fortified foods (such as some eggs, yogurt and drinks). There are three main types of omega-3 fatty acids — ALA, DHA and EPA. There are no set recommendations for the amount of DHA and EPA you should consume, but males age 14 and older should aim for 1.6 grams of ALA every day, while the goal is 1.1 daily grams of ALA for females age 14 and older. People breastfeeding should get 1.3 grams of ALA every day and those who are pregnant should aim for 1.4 grams of ALA. If you're not getting enough from your diet, you may want to ask your doctor about taking an omega-3 supplement.$23.98 at at at You Might Also Like 67 Best Gifts for Women That'll Make Her Smile The Best Pillows for Every Type of Sleeper


Gulf Insider
23-02-2025
- Health
- Gulf Insider
Combination of These Supplements and Exercise May Slow Biological Aging
Approximately one-fourth of people in the United States age 65 and older are in only fair or poor health. While we can't change our chronological age, various lifestyle practices can slow biological aging and delay the onset of chronic disease and frailty. Biological age refers to the health of the cells and tissues, which is dependent upon an array of genetic and environmental factors. A new clinical trial found that omega-3 fatty acid supplements have a small slowing effect on biological aging. Additional slowing occurs when these supplements are combined with vitamin D supplements and home exercise. An influential member of the natural health community, Dr. Joseph Mercola, a board-certified family medicine osteopathic physician, agrees that lifestyle factors can slow aging, yet he takes issue with some of the trial's findings. 'Relying solely on supplements is a poor substitute to get the nutrients your body was built to receive,' he told The Epoch Times in an email. Later in this article, he shares his recommendations for slowing aging. Findings The clinical trial, called the DO-HEALTH trial and published in Nature Aging, involved a prior phase and a current phase. The prior phase found three interventions linked to better health in aging, and the current phase found that the interventions also linked to better biological aging. Interventions Link to Improved Health Lead author Dr. Heike A. Bischoff-Ferrari, a clinical researcher and specialist in geriatric medicine at the University of Zurich, Switzerland, discussed the findings in an email with The Epoch Times. The prior phase of the same trial had more than 2,100 generally healthy adult participants aged 70 and older. 'We found omega-3 fatty acid supplements lowered the rate of falls by 10 percent and reduced the rate of infections by up to 13 percent,' she said. 'Also, the combination of omega-3, vitamin D, and exercise lowered the risk of pre-frailty by 39 percent and invasive cancer by 61 percent.' Click here to read more